AU2007298508B2 - Process for the synthesis of ibandronate sodium - Google Patents

Process for the synthesis of ibandronate sodium Download PDF

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Publication number
AU2007298508B2
AU2007298508B2 AU2007298508A AU2007298508A AU2007298508B2 AU 2007298508 B2 AU2007298508 B2 AU 2007298508B2 AU 2007298508 A AU2007298508 A AU 2007298508A AU 2007298508 A AU2007298508 A AU 2007298508A AU 2007298508 B2 AU2007298508 B2 AU 2007298508B2
Authority
AU
Australia
Prior art keywords
methyl
formula
amino
methylpentyl
propionate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2007298508A
Other languages
English (en)
Other versions
AU2007298508A1 (en
Inventor
Maruti Ganpati Ghagare
Rajendra Narayanrao Kankan
Dharamaraj Ramchandra Rao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cipla Ltd
Original Assignee
Cipla Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipla Ltd filed Critical Cipla Ltd
Publication of AU2007298508A1 publication Critical patent/AU2007298508A1/en
Application granted granted Critical
Publication of AU2007298508B2 publication Critical patent/AU2007298508B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/04—Sodium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
AU2007298508A 2006-06-23 2007-06-22 Process for the synthesis of ibandronate sodium Ceased AU2007298508B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN994/MUM/2006 2006-06-23
IN994MU2006 2006-06-23
PCT/IN2007/000255 WO2008035367A2 (en) 2006-06-23 2007-06-22 Process for the synthesis of ibandronate sodium

Publications (2)

Publication Number Publication Date
AU2007298508A1 AU2007298508A1 (en) 2008-03-27
AU2007298508B2 true AU2007298508B2 (en) 2012-02-09

Family

ID=39144580

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007298508A Ceased AU2007298508B2 (en) 2006-06-23 2007-06-22 Process for the synthesis of ibandronate sodium

Country Status (11)

Country Link
US (1) US8178712B2 (enExample)
EP (1) EP2038291B1 (enExample)
JP (1) JP5571378B2 (enExample)
KR (1) KR101425429B1 (enExample)
AT (1) ATE473990T1 (enExample)
AU (1) AU2007298508B2 (enExample)
CA (1) CA2652420C (enExample)
DE (1) DE602007007773D1 (enExample)
NZ (1) NZ573137A (enExample)
WO (1) WO2008035367A2 (enExample)
ZA (1) ZA200810024B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2041148A1 (en) * 2006-07-03 2009-04-01 Generics Ýuk¨Limited Novel process for the preparation of bisphosphonic acids
CN102093416B (zh) * 2011-03-17 2013-07-24 南京恒生制药有限公司 一种合成伊班膦酸钠的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2534391C2 (de) * 1975-08-01 1983-01-13 Henkel KGaA, 4000 Düsseldorf 1-Hydroxy-3-aminoalkan-1,1-diphosphonsäuren
JPS5414931A (en) * 1977-07-05 1979-02-03 Seitetsu Kagaku Co Ltd Preparation of n-benzylglycine
DE3623397A1 (de) * 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
JPS63190868A (ja) * 1986-08-21 1988-08-08 Kanegafuchi Chem Ind Co Ltd 光学活性スルホニルオキシ化合物及びその化合物を用いる光学活性アミンの製造方法
JPH11322687A (ja) * 1998-05-12 1999-11-24 Koei Chem Co Ltd ホルムアミド類の製造方法
JPH11349494A (ja) * 1998-06-03 1999-12-21 Toray Ind Inc 光学分割用分離剤および光学異性体の吸着分離方法
JP2001294558A (ja) * 2000-04-12 2001-10-23 Honshu Chem Ind Co Ltd ノルボルネンー２−カルボン酸エステル類及びその製造方法
ES2337063T3 (es) 2003-08-21 2010-04-20 Sun Pharmaceuticals Industries Ltd. Proceso para la preparacion de acido bisfosfonico.
JP4191008B2 (ja) * 2003-11-04 2008-12-03 花王株式会社 アミノカルボン酸エステルの製造法
US7723542B2 (en) 2003-12-23 2010-05-25 Trifarma S.P.A. Process for the preparation of alkyl- and aryl-diphosphonic acids and salts thereof
MX2007000087A (es) * 2004-06-23 2007-11-06 Teva Pharma Acido ibandronico solido y cristalino.
US7214818B2 (en) * 2004-10-29 2007-05-08 Hoffmann-La Roche Inc. Method for synthesizing bisphosphonate

Also Published As

Publication number Publication date
US20100228052A1 (en) 2010-09-09
AU2007298508A1 (en) 2008-03-27
EP2038291A2 (en) 2009-03-25
DE602007007773D1 (de) 2010-08-26
WO2008035367A2 (en) 2008-03-27
CA2652420C (en) 2014-01-14
CA2652420A1 (en) 2008-03-27
EP2038291B1 (en) 2010-07-14
KR20090023394A (ko) 2009-03-04
WO2008035367B1 (en) 2008-08-07
KR101425429B1 (ko) 2014-08-01
JP5571378B2 (ja) 2014-08-13
ATE473990T1 (de) 2010-07-15
US8178712B2 (en) 2012-05-15
NZ573137A (en) 2011-03-31
JP2009541305A (ja) 2009-11-26
ZA200810024B (en) 2009-10-28
WO2008035367A3 (en) 2008-05-22

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired