AU2007280216B2 - Pluripotent cells from rat and other species - Google Patents

Pluripotent cells from rat and other species Download PDF

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Publication number
AU2007280216B2
AU2007280216B2 AU2007280216A AU2007280216A AU2007280216B2 AU 2007280216 B2 AU2007280216 B2 AU 2007280216B2 AU 2007280216 A AU2007280216 A AU 2007280216A AU 2007280216 A AU2007280216 A AU 2007280216A AU 2007280216 B2 AU2007280216 B2 AU 2007280216B2
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cells
cell
pluripotent
rat
culture
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Ceased
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AU2007280216A
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AU2007280216A1 (en
Inventor
Austin Gerard Smith
Qi-Long Ying
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University of Edinburgh
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University of Edinburgh
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Priority to AU2013201718A priority Critical patent/AU2013201718B2/en
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0273Cloned vertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0606Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/101Bovine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/103Ovine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/108Swine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/115Basic fibroblast growth factor (bFGF, FGF-2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/16Activin; Inhibin; Mullerian inhibiting substance
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]
    • C12N2501/235Leukemia inhibitory factor [LIF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70Enzymes

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Reproductive Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Gynecology & Obstetrics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2007280216A 2006-08-01 2007-08-01 Pluripotent cells from rat and other species Ceased AU2007280216B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2013201718A AU2013201718B2 (en) 2006-08-01 2013-03-20 Pluripotent cells from rat and other species

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0615327.4 2006-08-01
GBGB0615327.4A GB0615327D0 (en) 2006-03-30 2006-08-01 Culture medium containing kinase inhibitors and uses thereof
GBGB0700479.9A GB0700479D0 (en) 2006-08-01 2007-01-10 Culture medium containing kinase inhibitors, and uses thereof
GB0700479.9 2007-01-10
PCT/GB2007/002913 WO2008015418A2 (en) 2006-08-01 2007-08-01 Pluripotent cells from rat and other species

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2013201718A Division AU2013201718B2 (en) 2006-08-01 2013-03-20 Pluripotent cells from rat and other species

Publications (2)

Publication Number Publication Date
AU2007280216A1 AU2007280216A1 (en) 2008-02-07
AU2007280216B2 true AU2007280216B2 (en) 2012-12-20

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AU2007280216A Ceased AU2007280216B2 (en) 2006-08-01 2007-08-01 Pluripotent cells from rat and other species

Country Status (7)

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US (2) US8431395B2 (enExample)
EP (1) EP2049654A2 (enExample)
JP (2) JP5456467B2 (enExample)
CN (2) CN101657535B (enExample)
AU (1) AU2007280216B2 (enExample)
GB (3) GB0615327D0 (enExample)
WO (1) WO2008015418A2 (enExample)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7682828B2 (en) 2003-11-26 2010-03-23 Whitehead Institute For Biomedical Research Methods for reprogramming somatic cells
US8357666B2 (en) * 2005-08-01 2013-01-22 Nupotential, Inc. Reprogramming a cell by inducing a pluripotent gene through RNA interference
US9074180B2 (en) * 2006-03-30 2015-07-07 The University Court Of The University Of Edinburgh Culture medium containing kinase inhibitors, and uses thereof
CN105861443A (zh) * 2007-04-07 2016-08-17 怀特黑德生物医学研究所 体细胞重编程
US9080145B2 (en) 2007-07-01 2015-07-14 Lifescan Corporation Single pluripotent stem cell culture
EP2198012B1 (en) * 2007-07-18 2014-12-31 Cellartis AB Cardiomyocyte-like cell clusters derived from hbs cells
CA3114827C (en) 2007-07-31 2023-09-05 Lifescan, Inc. Differentiation of human embryonic stem cells to pancreatic endocrine
EP3078738B1 (en) 2007-08-31 2020-05-20 Whitehead Institute for Biomedical Research Wnt pathway stimulation in reprogramming somatic cells
ES2690554T3 (es) * 2008-03-17 2018-11-21 The Scripps Research Institute Enfoques químicos y genéticos combinados para la generación de células madre pluripotentes inducidas
AU2009234423A1 (en) * 2008-04-07 2009-10-15 Nupotential, Inc. Reprogramming a cell by inducing a pluripotent gene through RNA interference
CN105671065A (zh) 2008-06-13 2016-06-15 怀特黑德生物医学研究所 细胞编程和重编程
AU2009267137A1 (en) 2008-06-30 2010-01-07 Centocor Ortho Biotech Inc. Differentiation of pluripotent stem cells
US8735156B2 (en) 2008-12-01 2014-05-27 The Board Of Regents Of The University Of Texas System Production and use of rat spermatogonial stem cell lines
ES2645869T3 (es) * 2008-12-17 2017-12-11 The Scripps Research Institute Generación y mantenimiento de células madre
US20110088107A1 (en) * 2009-04-24 2011-04-14 Yaqub Hanna Compositions and methods for deriving or culturing pluripotent cells
ES2638464T3 (es) * 2009-10-16 2017-10-20 The Scripps Research Institute Inducción de células pluripotentes
CN102762717A (zh) * 2009-12-01 2012-10-31 日本国立癌症研究中心 使用大鼠胚胎干细胞构建嵌合大鼠的方法
WO2011081222A1 (ja) * 2009-12-29 2011-07-07 武田薬品工業株式会社 膵ホルモン産生細胞の製造法
AU2011235212B2 (en) 2010-03-31 2014-07-31 The Scripps Research Institute Reprogramming cells
JPWO2011125948A1 (ja) * 2010-04-02 2013-07-11 独立行政法人理化学研究所 Es細胞の製造方法
EP3399026B1 (en) 2010-06-14 2024-06-26 The Scripps Research Institute Reprogramming of cells to a new fate
CN102344490B (zh) * 2010-07-30 2014-03-05 中国科学院上海生命科学研究院 抗小鼠Stk40的多克隆抗体及其制备
WO2012020845A1 (ja) * 2010-08-09 2012-02-16 武田薬品工業株式会社 膵ホルモン産生細胞の製造法
US10214722B2 (en) * 2010-09-07 2019-02-26 Technion Research & Development Foundation Limited Methods for expanding and maintaining human pluripotent stem cells (PSCs) in an undifferentiated state in a single cell suspension culture
JP6090855B2 (ja) * 2010-11-17 2017-03-08 国立大学法人京都大学 心筋細胞および/または心筋前駆細胞増殖剤ならびに心筋細胞および/または心筋前駆細胞の増殖方法
CN106893692B (zh) 2010-12-22 2021-11-26 菲特治疗公司 用于单细胞分选与增强ipsc重新编程的细胞培养平台
EP2668286A4 (en) * 2011-01-24 2015-07-01 Univ Ben Gurion METHOD FOR EVALUATING A MENTAL DISEASE
ES2902650T3 (es) 2011-06-21 2022-03-29 Novo Nordisk As Inducción eficiente de endodermo definitivo a partir de células madre pluripotentes
HUE068728T2 (hu) 2011-08-05 2025-01-28 Regeneron Pharma Humanizált univerzális könnyûláncú egerek
MX378871B (es) 2011-12-20 2025-03-10 Regeneron Pharma Ratones con cadena ligera humanizada.
JP6275120B2 (ja) 2012-04-25 2018-02-07 リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. 大きい標的化ベクターによるヌクレアーゼ媒介標的化
JP6475172B2 (ja) 2013-02-20 2019-02-27 リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. ラットの遺伝子組換え
EP3456831B1 (en) 2013-04-16 2021-07-14 Regeneron Pharmaceuticals, Inc. Targeted modification of rat genome
WO2014197934A1 (en) 2013-06-14 2014-12-18 The University Of Queensland Renal progenitor cells
MX388127B (es) 2013-12-11 2025-03-19 Regeneron Pharma Metodos y composiciones para la modificacion dirigida de un genoma.
SG10201807292YA (en) 2014-03-04 2018-09-27 Fate Therapeutics Inc Improved reprogramming methods and cell culture platforms
WO2015155738A2 (en) 2014-04-09 2015-10-15 Christopher Rudd Use of gsk-3 inhibitors or activators which modulate pd-1 or t-bet expression to modulate t cell immunity
JP6652334B2 (ja) 2014-05-31 2020-02-19 Jcrファーマ株式会社 ウリジンとn−アセチル−d−マンノサミンとを含有する培地
BR112016028564A2 (pt) 2014-06-06 2018-01-30 Regeneron Pharma método para modificar um locus-alvo em uma célula.
SG10201911411YA (en) 2014-06-26 2020-02-27 Regeneron Pharma Methods and compositions for targeted genetic modifications and methods of use
CA3176380A1 (en) 2014-11-21 2016-05-26 Regeneron Pharmaceuticals, Inc. Methods and compositions for targeted genetic modification using paired guide rnas
BR112017013104A2 (pt) 2014-12-19 2018-05-15 Regeneron Pharma métodos para modificar um locus genômico alvo em uma célula, para intensificar a recombinação homóloga em um locus genômico alvo em uma célula e para produzir uma geração f0 de um animal não humano.
CA2981277A1 (en) * 2015-03-30 2016-10-06 Ajinomoto Co., Inc. Human serum albumin-containing culture medium for growth of neural stem cells
AU2016338680B2 (en) 2015-10-16 2022-11-17 Fate Therapeutics, Inc. Platform for the induction and maintenance of ground state pluripotency
MA45479A (fr) 2016-04-14 2019-02-20 Janssen Biotech Inc Différenciation de cellules souches pluripotentes en cellules de l'endoderme de l'intestin moyen
JP2019537729A (ja) 2016-09-28 2019-12-26 オルガノボ インコーポレイテッド アッセイにおける人工腎臓組織の使用
WO2019208787A1 (ja) * 2018-04-27 2019-10-31 株式会社カネカ 原始腸管細胞の製造方法
SG11202104941YA (en) * 2018-11-21 2021-06-29 Agency Science Tech & Res Generation of mature kupffer cells
CN111238897B (zh) * 2020-02-18 2023-03-28 上海市皮肤病医院 生物标本的处理方法与处理剂
CN116096860A (zh) * 2020-07-02 2023-05-09 阿塞尔塔有限公司 来自延迟胚胎的哺乳动物牲畜多能干细胞系
EP4386082A4 (en) * 2021-08-10 2025-08-20 Kaneka Corp PROCESS FOR THE PRODUCTION OF PLURIPOTENT STEM CELLS
CN115927166A (zh) * 2022-12-06 2023-04-07 云南省第一人民医院 一种大鼠原始内胚层干细胞分离建系的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005085427A1 (ja) * 2004-03-04 2005-09-15 Dainippon Sumitomo Pharma Co., Ltd. ラット胚性幹細胞

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9308271D0 (en) 1993-04-21 1993-06-02 Univ Edinburgh Method of isolating and/or enriching and/or selectively propagating pluripotential animal cells and animals for use in said method
WO1995006716A1 (en) 1993-08-30 1995-03-09 Northwestern University Rat pluripotent embryonic stem cells and method of obtaining and using same
EP0941310A1 (en) 1996-10-11 1999-09-15 THE TEXAS A&M UNIVERSITY SYSTEM Methods for the generation of primordial germ cells and transgenic animal species
US6214795B1 (en) * 1996-11-12 2001-04-10 Praecis Pharmaceuticals, Inc. Peptide compounds useful for modulating FGF receptor activity
EP0986635A4 (en) 1997-01-10 2001-11-07 Life Technologies Inc SERUM SUBSTITUTE FOR EMBRYONIC STEM CELLS
WO1999027076A1 (en) * 1997-11-25 1999-06-03 Arc Genomic Research Pluripotent embryonic stem cells and methods of obtaining them
GB9819912D0 (en) 1998-09-11 1998-11-04 Univ Edinburgh Propagation and/or derivation of embryonic stem cells
US7455983B2 (en) * 2000-01-11 2008-11-25 Geron Corporation Medium for growing human embryonic stem cells
US20020045260A1 (en) * 2000-10-17 2002-04-18 Shih-Chieh Hung Method of isolating mesenchymal stem cells
JP2002176973A (ja) 2000-12-14 2002-06-25 Shigeo Saito 哺乳動物胚性幹細胞とその樹立方法並びにその継代培養方法
DE60301953T2 (de) 2002-03-05 2006-07-27 Artemis Pharmaceuticals Gmbh Durch inzucht erzeugte von embryonalen stammzellen abgeleitete mäuse
GB0210539D0 (en) 2002-05-08 2002-06-19 Univ Edinburgh Control of es cell self renewal and lineage specification, and medium therefor
US7338957B2 (en) 2003-08-28 2008-03-04 Irm Llc Compounds and compositions as protein kinase inhibitors
KR101221302B1 (ko) * 2003-12-23 2013-01-11 비아싸이트, 인크. 완전 내배엽
JP2007530654A (ja) 2004-03-30 2007-11-01 ファイザー・プロダクツ・インク シグナル伝達阻害剤の組合せ
WO2005110438A2 (en) * 2004-04-15 2005-11-24 Massachusetts Institute Of Technology Methods and products related to the intracellular delivery of polysaccharides
US20080268533A1 (en) 2004-08-25 2008-10-30 University Of Georgia Research Foundation, Inc. Methods and Compositions Utilizing Myc and Gsk3Beta to Manipulate the Pluripotency of Embryonic Stem Cells
MX2007015610A (es) 2005-06-10 2008-02-21 Irm Llc Compuestos que mantienen la fluripotencia de las celulas totipotentes embrionarias.
US20070128669A1 (en) 2005-11-28 2007-06-07 Institute For Chemical Genomics Serum-free expansion of cells in culture
US9074180B2 (en) 2006-03-30 2015-07-07 The University Court Of The University Of Edinburgh Culture medium containing kinase inhibitors, and uses thereof
US20090281418A1 (en) * 2006-04-03 2009-11-12 Koninklijke Philips Electomics N.V. Determining tissue surrounding an object being inserted into a patient
EP2018167A4 (en) 2006-05-15 2010-07-14 Irm Llc COMPOSITIONS AND METHODS AS INHIBITORS OF FGF RECEPTOR KINASES

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005085427A1 (ja) * 2004-03-04 2005-09-15 Dainippon Sumitomo Pharma Co., Ltd. ラット胚性幹細胞

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BAHARVAND, H. et al Development, Growth & Differentiation. February 2006, Vol.48, No.2, pages 117-128. *
LI, X. et al. Molecular Reproduction amd Development. October 2005, Vol.72, no.2, pages 152-160 *

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Publication number Publication date
WO2008015418A3 (en) 2008-04-10
EP2049654A2 (en) 2009-04-22
GB0716426D0 (en) 2007-10-10
GB0615327D0 (en) 2006-09-13
CN101657535A (zh) 2010-02-24
GB0700479D0 (en) 2007-02-21
GB2451523B (en) 2010-03-17
CN104531610A (zh) 2015-04-22
JP5456467B2 (ja) 2014-03-26
US20130333058A1 (en) 2013-12-12
US8431395B2 (en) 2013-04-30
JP2009545302A (ja) 2009-12-24
AU2007280216A1 (en) 2008-02-07
CN101657535B (zh) 2016-03-02
GB2451523A (en) 2009-02-04
US20080066197A1 (en) 2008-03-13
WO2008015418A2 (en) 2008-02-07
JP2013176400A (ja) 2013-09-09
GB2451523A8 (en) 2009-02-18

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