GB0615327D0 - Culture medium containing kinase inhibitors and uses thereof - Google Patents

Culture medium containing kinase inhibitors and uses thereof

Info

Publication number
GB0615327D0
GB0615327D0 GBGB0615327.4A GB0615327A GB0615327D0 GB 0615327 D0 GB0615327 D0 GB 0615327D0 GB 0615327 A GB0615327 A GB 0615327A GB 0615327 D0 GB0615327 D0 GB 0615327D0
Authority
GB
United Kingdom
Prior art keywords
culture medium
medium containing
kinase inhibitors
containing kinase
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0615327.4A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Edinburgh
Original Assignee
University of Edinburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0606392.9A external-priority patent/GB0606392D0/en
Priority to GBGB0615327.4A priority Critical patent/GB0615327D0/en
Application filed by University of Edinburgh filed Critical University of Edinburgh
Publication of GB0615327D0 publication Critical patent/GB0615327D0/en
Priority to GBGB0700479.9A priority patent/GB0700479D0/en
Priority to PCT/GB2007/001163 priority patent/WO2007113505A2/en
Priority to EP07732217A priority patent/EP1999249B8/en
Priority to AT07732217T priority patent/ATE530637T1/de
Priority to GB0706239A priority patent/GB2436737B/en
Priority to JP2009502219A priority patent/JP5680850B2/ja
Priority to US11/694,351 priority patent/US9074180B2/en
Priority to CA002645170A priority patent/CA2645170A1/en
Priority to EP11182239A priority patent/EP2457995A1/en
Priority to TW096111227A priority patent/TW200815597A/zh
Priority to AU2007232393A priority patent/AU2007232393A1/en
Priority to CN200780036720.1A priority patent/CN101657535B/zh
Priority to EP07766403A priority patent/EP2049654A2/en
Priority to CN201410720584.XA priority patent/CN104531610A/zh
Priority to AU2007280216A priority patent/AU2007280216B2/en
Priority to US11/832,317 priority patent/US8431395B2/en
Priority to JP2009522328A priority patent/JP5456467B2/ja
Priority to GB0716426A priority patent/GB2451523B/en
Priority to PCT/GB2007/002913 priority patent/WO2008015418A2/en
Priority to IL193495A priority patent/IL193495A0/en
Priority to US12/581,981 priority patent/US20100041137A1/en
Priority to JP2013011454A priority patent/JP5728036B2/ja
Priority to US13/857,449 priority patent/US20130333058A1/en
Priority to JP2013127052A priority patent/JP2013176400A/ja
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0273—Cloned vertebrates
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/101—Bovine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/103—Ovine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/108—Swine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/235—Leukemia inhibitory factor [LIF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Reproductive Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Gynecology & Obstetrics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
GBGB0615327.4A 2006-03-30 2006-08-01 Culture medium containing kinase inhibitors and uses thereof Ceased GB0615327D0 (en)

Priority Applications (25)

Application Number Priority Date Filing Date Title
GBGB0615327.4A GB0615327D0 (en) 2006-03-30 2006-08-01 Culture medium containing kinase inhibitors and uses thereof
GBGB0700479.9A GB0700479D0 (en) 2006-08-01 2007-01-10 Culture medium containing kinase inhibitors, and uses thereof
AU2007232393A AU2007232393A1 (en) 2006-03-30 2007-03-30 Culture medium containing kinase inhibitors. and uses thereof
TW096111227A TW200815597A (en) 2006-03-30 2007-03-30 Culture medium containing kinase inhibitors, and uses thereof
EP07732217A EP1999249B8 (en) 2006-03-30 2007-03-30 Culture medium containing kinase inhibitors. and uses thereof
PCT/GB2007/001163 WO2007113505A2 (en) 2006-03-30 2007-03-30 Culture medium containing kinase inhibitors. and uses thereof
AT07732217T ATE530637T1 (de) 2006-03-30 2007-03-30 Kulturmedium mit kinasehemmern und verwendung
GB0706239A GB2436737B (en) 2006-03-30 2007-03-30 Culture medium containing kinase inhibitors,and uses thereof
JP2009502219A JP5680850B2 (ja) 2006-03-30 2007-03-30 キナーゼインヒビターを含む培養培地およびその使用
US11/694,351 US9074180B2 (en) 2006-03-30 2007-03-30 Culture medium containing kinase inhibitors, and uses thereof
CA002645170A CA2645170A1 (en) 2006-03-30 2007-03-30 Culture medium containing kinase inhibitors, and uses thereof
EP11182239A EP2457995A1 (en) 2006-03-30 2007-03-30 Culture medium containing kinase inhibitors, and uses thereof
PCT/GB2007/002913 WO2008015418A2 (en) 2006-08-01 2007-08-01 Pluripotent cells from rat and other species
CN200780036720.1A CN101657535B (zh) 2006-08-01 2007-08-01 源于大鼠及其它动物的多潜能细胞
EP07766403A EP2049654A2 (en) 2006-08-01 2007-08-01 Pluripotent cells from rat and other species
GB0716426A GB2451523B (en) 2006-08-01 2007-08-01 Pluripotent cells from rat and other species
CN201410720584.XA CN104531610A (zh) 2006-08-01 2007-08-01 源于大鼠及其它动物的多潜能细胞
AU2007280216A AU2007280216B2 (en) 2006-08-01 2007-08-01 Pluripotent cells from rat and other species
US11/832,317 US8431395B2 (en) 2006-08-01 2007-08-01 Pluripotent cells from rat and other species
JP2009522328A JP5456467B2 (ja) 2006-08-01 2007-08-01 ラットおよび他種由来の多能性細胞
IL193495A IL193495A0 (en) 2006-03-30 2008-08-17 Culture medium containing kinase inhibitors and uses thereof
US12/581,981 US20100041137A1 (en) 2006-03-30 2009-10-20 Culture medium containing kinase inhibitors, and uses thereof
JP2013011454A JP5728036B2 (ja) 2006-03-30 2013-01-24 キナーゼインヒビターを含む培養培地およびその使用
US13/857,449 US20130333058A1 (en) 2006-08-01 2013-04-05 Pluripotent Cells From Rat and Other Species
JP2013127052A JP2013176400A (ja) 2006-08-01 2013-06-17 ラットおよび他種由来の多能性細胞

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0606392.9A GB0606392D0 (en) 2006-03-30 2006-03-30 Culture medium containing kinase inhibitors, and uses thereof
GBGB0615327.4A GB0615327D0 (en) 2006-03-30 2006-08-01 Culture medium containing kinase inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
GB0615327D0 true GB0615327D0 (en) 2006-09-13

Family

ID=37809760

Family Applications (3)

Application Number Title Priority Date Filing Date
GBGB0615327.4A Ceased GB0615327D0 (en) 2006-03-30 2006-08-01 Culture medium containing kinase inhibitors and uses thereof
GBGB0700479.9A Ceased GB0700479D0 (en) 2006-08-01 2007-01-10 Culture medium containing kinase inhibitors, and uses thereof
GB0716426A Expired - Fee Related GB2451523B (en) 2006-08-01 2007-08-01 Pluripotent cells from rat and other species

Family Applications After (2)

Application Number Title Priority Date Filing Date
GBGB0700479.9A Ceased GB0700479D0 (en) 2006-08-01 2007-01-10 Culture medium containing kinase inhibitors, and uses thereof
GB0716426A Expired - Fee Related GB2451523B (en) 2006-08-01 2007-08-01 Pluripotent cells from rat and other species

Country Status (7)

Country Link
US (2) US8431395B2 (enExample)
EP (1) EP2049654A2 (enExample)
JP (2) JP5456467B2 (enExample)
CN (2) CN104531610A (enExample)
AU (1) AU2007280216B2 (enExample)
GB (3) GB0615327D0 (enExample)
WO (1) WO2008015418A2 (enExample)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7682828B2 (en) * 2003-11-26 2010-03-23 Whitehead Institute For Biomedical Research Methods for reprogramming somatic cells
US8357666B2 (en) * 2005-08-01 2013-01-22 Nupotential, Inc. Reprogramming a cell by inducing a pluripotent gene through RNA interference
WO2007113505A2 (en) * 2006-03-30 2007-10-11 The University Court Of The University Of Edinburgh Culture medium containing kinase inhibitors. and uses thereof
MX348010B (es) 2007-04-07 2017-05-23 Whitehead Inst Biomedical Res Reprogramacion de celulas somaticas.
US9080145B2 (en) 2007-07-01 2015-07-14 Lifescan Corporation Single pluripotent stem cell culture
CN101918541A (zh) * 2007-07-18 2010-12-15 塞拉提斯股份公司 衍生自hBS细胞的心肌细胞样细胞簇
RU2473685C2 (ru) 2007-07-31 2013-01-27 Лайфскен, Инк. Дифференцировка человеческих эмбриональных стволовых клеток
WO2009032194A1 (en) 2007-08-31 2009-03-12 Whitehead Institute For Biomedical Research Wnt pathway stimulation in reprogramming somatic cells
JP5951254B2 (ja) * 2008-03-17 2016-07-13 ザ スクリプス リサーチ インスティテュート 人工多能性幹細胞を作製するための化学的手法と遺伝的手法の組み合わせ法
CN102083982A (zh) * 2008-04-07 2011-06-01 纽珀滕索有限公司 通过rna干扰引入复能基因而重编程细胞
WO2009152529A2 (en) 2008-06-13 2009-12-17 Whitehead Institute For Biomedical Research Nine Cambridge Center Programming and reprogramming of cells
CA2729121C (en) 2008-06-30 2019-04-09 Centocor Ortho Biotech Inc. Differentiation of pluripotent stem cells
US8735156B2 (en) 2008-12-01 2014-05-27 The Board Of Regents Of The University Of Texas System Production and use of rat spermatogonial stem cell lines
SG172160A1 (en) * 2008-12-17 2011-07-28 Scripps Research Inst Generation and maintenance of stem cells
EP2421956A4 (en) * 2009-04-24 2013-10-02 Whitehead Biomedical Inst COMPOSITIONS AND METHODS FOR OBTAINING OR CULTURING PLURIPOTENTER CELLS
MX389666B (es) 2009-10-16 2025-03-19 Scripps Research Inst Induccion de celulas pluripotentes.
WO2011068103A1 (ja) 2009-12-01 2011-06-09 独立行政法人国立がん研究センター ラット胚性幹細胞を用いたキメララットの作製法
EP2505639B1 (en) * 2009-12-29 2018-09-19 Takeda Pharmaceutical Company Limited Method for manufacturing pancreatic-hormone-producing cells
CA2800498C (en) 2010-03-31 2021-11-16 The Scripps Research Institute Reprogramming cells
EP2554659A4 (en) * 2010-04-02 2013-09-25 Riken PROCESS FOR PREPARING ES CELLS
WO2011159726A2 (en) 2010-06-14 2011-12-22 The Scripps Research Institute Reprogramming of cells to a new fate
CN102344490B (zh) * 2010-07-30 2014-03-05 中国科学院上海生命科学研究院 抗小鼠Stk40的多克隆抗体及其制备
AU2011290123B2 (en) * 2010-08-09 2016-11-10 Takeda Pharmaceutical Company Limited Method of producing pancreatic hormone-producing cells
CA3150342A1 (en) * 2010-09-07 2012-03-15 Technion Research & Development Foundation Limited Novel methods and culture media for culturing pluripotent stem cells
EP2640829A4 (en) * 2010-11-17 2014-06-11 Univ Kyoto CARDIOMYOCYTE AND / OR CARDIOVORA CELL PROLIFERATING AGENTS AND METHOD FOR PROLIFERATING CARDIOMYOCYTES AND / OR CARDIOVORA CELLS
US9732319B2 (en) 2010-12-22 2017-08-15 Fate Therapeutics, Inc. Cell culture platform for single cell sorting and enhanced reprogramming of iPSCs
EP2668286A4 (en) * 2011-01-24 2015-07-01 Univ Ben Gurion METHOD FOR EVALUATING A MENTAL DISEASE
WO2012175633A1 (en) 2011-06-21 2012-12-27 Novo Nordisk A/S Efficient induction of definitive endoderm from pluripotent stem cells
ES2872081T3 (es) 2011-08-05 2021-11-02 Regeneron Pharma Ratones con cadena ligera universal humanizada
SMT201900296T1 (it) 2011-12-20 2019-07-11 Regeneron Pharma Topi di catena leggera umanizzata
ES2683071T3 (es) 2012-04-25 2018-09-24 Regeneron Pharmaceuticals, Inc. Direccionamiento mediado por nucleasas con grandes vectores de direccionamiento
MX2015010841A (es) 2013-02-20 2016-05-09 Regeneron Pharma Modificacion genetica de ratas.
DK3456831T3 (da) 2013-04-16 2021-09-06 Regeneron Pharma Målrettet modifikation af rottegenom
NZ715302A (en) 2013-06-14 2021-12-24 Univ Queensland Renal progenitor cells
MX388127B (es) 2013-12-11 2025-03-19 Regeneron Pharma Metodos y composiciones para la modificacion dirigida de un genoma.
CN120536341A (zh) 2014-03-04 2025-08-26 菲特治疗公司 改良的重编程方法和细胞培养平台
WO2015155738A2 (en) 2014-04-09 2015-10-15 Christopher Rudd Use of gsk-3 inhibitors or activators which modulate pd-1 or t-bet expression to modulate t cell immunity
JP6652334B2 (ja) * 2014-05-31 2020-02-19 Jcrファーマ株式会社 ウリジンとn−アセチル−d−マンノサミンとを含有する培地
DK3152312T3 (da) 2014-06-06 2020-04-06 Regeneron Pharma Fremgangsmåder og sammensætninger til modifikation af et mållocus
DK3161128T3 (en) 2014-06-26 2018-11-05 Regeneron Pharma METHODS AND COMPOSITIONS FOR TARGETED GENTICAL MODIFICATIONS AND PROCEDURES FOR USE THEREOF
EP3221457B1 (en) 2014-11-21 2019-03-20 Regeneron Pharmaceuticals, Inc. Methods and compositions for targeted genetic modification using paired guide rnas
MX388784B (es) 2014-12-19 2025-03-20 Regeneron Pharma Métodos y composiciones para la modificación genética dirigida a través de direccionamiento múltiple de una sola etapa.
EP3279318A4 (en) * 2015-03-30 2018-08-29 Ajinomoto Co., Inc. Human serum albumin-containing culture medium for growth of neural stem cells
CN117737124A (zh) 2015-10-16 2024-03-22 菲特治疗公司 用于诱导和维护基态多能性的平台
WO2017180361A1 (en) 2016-04-14 2017-10-19 Janssen Biotech, Inc. Differentiation of pluripotent stem cells to intestinal midgut endoderm cells
AU2017335841A1 (en) 2016-09-28 2019-04-04 Organovo, Inc. Use of engineered renal tissues in assays
US20210246429A1 (en) * 2018-04-27 2021-08-12 Kaneka Corporation Method for producing primitive gut tube cells
EP3884042A4 (en) * 2018-11-21 2022-08-24 Agency For Science, Technology And Research GENERATION OF TIRES AND COPPER CELLS
CN111238897B (zh) * 2020-02-18 2023-03-28 上海市皮肤病医院 生物标本的处理方法与处理剂
AU2021300644A1 (en) * 2020-07-02 2023-03-02 Accellta Ltd. Mammalian livestock pluripotent stem cells from delayed embryos
WO2023017806A1 (ja) * 2021-08-10 2023-02-16 株式会社カネカ 多能性幹細胞の製造方法
CN115927166A (zh) * 2022-12-06 2023-04-07 云南省第一人民医院 一种大鼠原始内胚层干细胞分离建系的方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9308271D0 (en) 1993-04-21 1993-06-02 Univ Edinburgh Method of isolating and/or enriching and/or selectively propagating pluripotential animal cells and animals for use in said method
EP0716690A1 (en) 1993-08-30 1996-06-19 Northwestern University Rat pluripotent embryonic stem cells and method of obtaining and using same
AU4984697A (en) * 1996-10-11 1998-05-11 The Texas A & M University System Methods for the generation of primordial germ cells and transgenic animal species
US6214795B1 (en) * 1996-11-12 2001-04-10 Praecis Pharmaceuticals, Inc. Peptide compounds useful for modulating FGF receptor activity
JP2001508302A (ja) 1997-01-10 2001-06-26 ライフ テクノロジーズ,インコーポレイテッド 胚性幹細胞血清置換
WO1999027076A1 (en) * 1997-11-25 1999-06-03 Arc Genomic Research Pluripotent embryonic stem cells and methods of obtaining them
GB9819912D0 (en) 1998-09-11 1998-11-04 Univ Edinburgh Propagation and/or derivation of embryonic stem cells
US7455983B2 (en) * 2000-01-11 2008-11-25 Geron Corporation Medium for growing human embryonic stem cells
US20020045260A1 (en) * 2000-10-17 2002-04-18 Shih-Chieh Hung Method of isolating mesenchymal stem cells
JP2002176973A (ja) 2000-12-14 2002-06-25 Shigeo Saito 哺乳動物胚性幹細胞とその樹立方法並びにその継代培養方法
ATE306810T1 (de) 2002-03-05 2005-11-15 Artemis Pharmaceuticals Gmbh Durch inzucht erzeugte von embryonalen stammzellen abgeleitete mäuse
GB0210539D0 (en) 2002-05-08 2002-06-19 Univ Edinburgh Control of es cell self renewal and lineage specification, and medium therefor
US7338957B2 (en) 2003-08-28 2008-03-04 Irm Llc Compounds and compositions as protein kinase inhibitors
EP2722387B1 (en) * 2003-12-23 2019-12-11 Viacyte, Inc. Definitive endoderm
KR101386690B1 (ko) 2004-03-04 2014-04-22 도쿠리츠교세이호진 고쿠리츠간켄큐센터 래트 배아 줄기 세포
BRPI0509580A (pt) 2004-03-30 2007-11-27 Pfizer Prod Inc combinações de inibidores de transdução de sinal
WO2005110438A2 (en) * 2004-04-15 2005-11-24 Massachusetts Institute Of Technology Methods and products related to the intracellular delivery of polysaccharides
WO2006026473A2 (en) 2004-08-25 2006-03-09 University Of Georgia Research Foundation, Inc. METHODS AND COMPOSITIONS UTILIZING MYC AND GSK3ß TO MANIPULATE THE PLURIPOTENCY OF EMBRYONIC STEM CELLS
AU2006257859B2 (en) 2005-06-10 2009-12-10 Irm Llc Compounds that maintain pluripotency of embryonic stem cells
ATE446509T1 (de) * 2005-11-28 2009-11-15 Choongwae Pharma Corp Serumfreie expansion von zellen in kultur
WO2007113505A2 (en) * 2006-03-30 2007-10-11 The University Court Of The University Of Edinburgh Culture medium containing kinase inhibitors. and uses thereof
CN101410060A (zh) * 2006-04-03 2009-04-15 皇家飞利浦电子股份有限公司 测定插入患者体内的对象周围的组织
JP2009537520A (ja) 2006-05-15 2009-10-29 アイアールエム・リミテッド・ライアビリティ・カンパニー Fgf受容体キナーゼ阻害剤のための組成物および方法

Also Published As

Publication number Publication date
AU2007280216A1 (en) 2008-02-07
US20080066197A1 (en) 2008-03-13
GB2451523A (en) 2009-02-04
CN104531610A (zh) 2015-04-22
GB0716426D0 (en) 2007-10-10
CN101657535B (zh) 2016-03-02
JP5456467B2 (ja) 2014-03-26
CN101657535A (zh) 2010-02-24
AU2007280216B2 (en) 2012-12-20
US20130333058A1 (en) 2013-12-12
EP2049654A2 (en) 2009-04-22
US8431395B2 (en) 2013-04-30
GB2451523A8 (en) 2009-02-18
WO2008015418A3 (en) 2008-04-10
GB0700479D0 (en) 2007-02-21
JP2009545302A (ja) 2009-12-24
WO2008015418A2 (en) 2008-02-07
JP2013176400A (ja) 2013-09-09
GB2451523B (en) 2010-03-17

Similar Documents

Publication Publication Date Title
GB0700479D0 (en) Culture medium containing kinase inhibitors, and uses thereof
WO2007113505A3 (en) Culture medium containing kinase inhibitors. and uses thereof
GB0505970D0 (en) Culture medium containing kinase inhibitor, and uses thereof
WO2010008486A3 (en) Pluripotent cell lines and methods of use thereof
MX2008013582A (es) Derivados de pirimidina como inhibidores de fosfatidilinositol-3-c inasa.
GB2446525A (en) Stem cell culture medium and method
MY153727A (en) Pyridazinone derivatives
AU2017263716A1 (en) Haematopoietic stem/progenitor cells
PL2094107T3 (pl) Kompozycja redukująca zawartość mikotoksyny
DK2049501T3 (da) Hydroxyleret og methoxyleret cyclopenta [D]-pyrimidiner som AKT-proteinkinase-inhibitorer
EP2497470B8 (en) Imidazotriazines and imidazopyrimidines as kinase inhibitors
WO2012065067A3 (en) Immortalization of epithelial cells and methods of use
UA99311C2 (en) Inhibitors of c-fms kinase
MX2009012708A (es) Derivados de piridazinona.
SG179085A1 (en) Pi3 kinase inhibitors and uses thereof
ATE530636T1 (de) Zellkultur
TN2011000207A1 (en) Akt and p70 s6 kinase inhibitors
WO2010035136A3 (en) Expansion of embryonic stem cells
IL217321A0 (en) Novel (6-oxo-1,6 - dihydro - pyrimidin - 2 - yl) - amide derivatives, prepartion thereof, and pharamaceutical use thereof as akt (pkb) phosphorylation inhibitors
MX2009008122A (es) Composiciones farmaceuticas y metodos para utilizar temozolomida e inhibidores de quinasa multidirigidos.
WO2007084949A3 (en) Modulators of cardiac cell hypertrophy and hyperplasia
WO2007109067A3 (en) Non-random aptamer libraries and methods for making
SG151171A1 (en) Association between an anti-atherothrombotic and an angiotensin- converting enzyme inhibitor
HK1133578A (en) Kinase inhibitors, and methods of using and identifying kinase inhibitors
HK40089747A (en) Halogenated-heteroaryl and other heterocyclic kinase inhibitors, and uses thereof

Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)