GB0615327D0 - Culture medium containing kinase inhibitors and uses thereof - Google Patents
Culture medium containing kinase inhibitors and uses thereofInfo
- Publication number
- GB0615327D0 GB0615327D0 GBGB0615327.4A GB0615327A GB0615327D0 GB 0615327 D0 GB0615327 D0 GB 0615327D0 GB 0615327 A GB0615327 A GB 0615327A GB 0615327 D0 GB0615327 D0 GB 0615327D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- culture medium
- medium containing
- kinase inhibitors
- containing kinase
- inhibitor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 239000001963 growth medium Substances 0.000 title 1
- 229940043355 kinase inhibitor Drugs 0.000 title 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 title 1
- 108091008794 FGF receptors Proteins 0.000 abstract 1
- 102000044168 Fibroblast Growth Factor Receptor Human genes 0.000 abstract 1
- 102000001267 GSK3 Human genes 0.000 abstract 1
- 108060006662 GSK3 Proteins 0.000 abstract 1
- 229940124647 MEK inhibitor Drugs 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000002829 mitogen activated protein kinase inhibitor Substances 0.000 abstract 1
- NFVJNJQRWPQVOA-UHFFFAOYSA-N n-[2-chloro-5-(trifluoromethyl)phenyl]-2-[3-(4-ethyl-5-ethylsulfanyl-1,2,4-triazol-3-yl)piperidin-1-yl]acetamide Chemical compound CCN1C(SCC)=NN=C1C1CN(CC(=O)NC=2C(=CC=C(C=2)C(F)(F)F)Cl)CCC1 NFVJNJQRWPQVOA-UHFFFAOYSA-N 0.000 abstract 1
- 239000004017 serum-free culture medium Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
- A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0273—Cloned vertebrates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/101—Bovine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/103—Ovine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/108—Swine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/235—Leukemia inhibitory factor [LIF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Environmental Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Reproductive Health (AREA)
- Chemical & Material Sciences (AREA)
- Gynecology & Obstetrics (AREA)
- Developmental Biology & Embryology (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Biodiversity & Conservation Biology (AREA)
- Animal Husbandry (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pathology (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (25)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0615327.4A GB0615327D0 (en) | 2006-03-30 | 2006-08-01 | Culture medium containing kinase inhibitors and uses thereof |
| GBGB0700479.9A GB0700479D0 (en) | 2006-08-01 | 2007-01-10 | Culture medium containing kinase inhibitors, and uses thereof |
| AU2007232393A AU2007232393A1 (en) | 2006-03-30 | 2007-03-30 | Culture medium containing kinase inhibitors. and uses thereof |
| AT07732217T ATE530637T1 (de) | 2006-03-30 | 2007-03-30 | Kulturmedium mit kinasehemmern und verwendung |
| JP2009502219A JP5680850B2 (ja) | 2006-03-30 | 2007-03-30 | キナーゼインヒビターを含む培養培地およびその使用 |
| EP07732217A EP1999249B8 (en) | 2006-03-30 | 2007-03-30 | Culture medium containing kinase inhibitors. and uses thereof |
| CA002645170A CA2645170A1 (en) | 2006-03-30 | 2007-03-30 | Culture medium containing kinase inhibitors, and uses thereof |
| US11/694,351 US9074180B2 (en) | 2006-03-30 | 2007-03-30 | Culture medium containing kinase inhibitors, and uses thereof |
| PCT/GB2007/001163 WO2007113505A2 (en) | 2006-03-30 | 2007-03-30 | Culture medium containing kinase inhibitors. and uses thereof |
| GB0706239A GB2436737B (en) | 2006-03-30 | 2007-03-30 | Culture medium containing kinase inhibitors,and uses thereof |
| EP11182239A EP2457995A1 (en) | 2006-03-30 | 2007-03-30 | Culture medium containing kinase inhibitors, and uses thereof |
| TW096111227A TW200815597A (en) | 2006-03-30 | 2007-03-30 | Culture medium containing kinase inhibitors, and uses thereof |
| CN201410720584.XA CN104531610A (zh) | 2006-08-01 | 2007-08-01 | 源于大鼠及其它动物的多潜能细胞 |
| US11/832,317 US8431395B2 (en) | 2006-08-01 | 2007-08-01 | Pluripotent cells from rat and other species |
| AU2007280216A AU2007280216B2 (en) | 2006-08-01 | 2007-08-01 | Pluripotent cells from rat and other species |
| GB0716426A GB2451523B (en) | 2006-08-01 | 2007-08-01 | Pluripotent cells from rat and other species |
| JP2009522328A JP5456467B2 (ja) | 2006-08-01 | 2007-08-01 | ラットおよび他種由来の多能性細胞 |
| EP07766403A EP2049654A2 (en) | 2006-08-01 | 2007-08-01 | Pluripotent cells from rat and other species |
| PCT/GB2007/002913 WO2008015418A2 (en) | 2006-08-01 | 2007-08-01 | Pluripotent cells from rat and other species |
| CN200780036720.1A CN101657535B (zh) | 2006-08-01 | 2007-08-01 | 源于大鼠及其它动物的多潜能细胞 |
| IL193495A IL193495A0 (en) | 2006-03-30 | 2008-08-17 | Culture medium containing kinase inhibitors and uses thereof |
| US12/581,981 US20100041137A1 (en) | 2006-03-30 | 2009-10-20 | Culture medium containing kinase inhibitors, and uses thereof |
| JP2013011454A JP5728036B2 (ja) | 2006-03-30 | 2013-01-24 | キナーゼインヒビターを含む培養培地およびその使用 |
| US13/857,449 US20130333058A1 (en) | 2006-08-01 | 2013-04-05 | Pluripotent Cells From Rat and Other Species |
| JP2013127052A JP2013176400A (ja) | 2006-08-01 | 2013-06-17 | ラットおよび他種由来の多能性細胞 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0606392.9A GB0606392D0 (en) | 2006-03-30 | 2006-03-30 | Culture medium containing kinase inhibitors, and uses thereof |
| GBGB0615327.4A GB0615327D0 (en) | 2006-03-30 | 2006-08-01 | Culture medium containing kinase inhibitors and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB0615327D0 true GB0615327D0 (en) | 2006-09-13 |
Family
ID=37809760
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB0615327.4A Ceased GB0615327D0 (en) | 2006-03-30 | 2006-08-01 | Culture medium containing kinase inhibitors and uses thereof |
| GBGB0700479.9A Ceased GB0700479D0 (en) | 2006-08-01 | 2007-01-10 | Culture medium containing kinase inhibitors, and uses thereof |
| GB0716426A Expired - Fee Related GB2451523B (en) | 2006-08-01 | 2007-08-01 | Pluripotent cells from rat and other species |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB0700479.9A Ceased GB0700479D0 (en) | 2006-08-01 | 2007-01-10 | Culture medium containing kinase inhibitors, and uses thereof |
| GB0716426A Expired - Fee Related GB2451523B (en) | 2006-08-01 | 2007-08-01 | Pluripotent cells from rat and other species |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8431395B2 (enExample) |
| EP (1) | EP2049654A2 (enExample) |
| JP (2) | JP5456467B2 (enExample) |
| CN (2) | CN101657535B (enExample) |
| AU (1) | AU2007280216B2 (enExample) |
| GB (3) | GB0615327D0 (enExample) |
| WO (1) | WO2008015418A2 (enExample) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7682828B2 (en) | 2003-11-26 | 2010-03-23 | Whitehead Institute For Biomedical Research | Methods for reprogramming somatic cells |
| US8357666B2 (en) * | 2005-08-01 | 2013-01-22 | Nupotential, Inc. | Reprogramming a cell by inducing a pluripotent gene through RNA interference |
| US9074180B2 (en) * | 2006-03-30 | 2015-07-07 | The University Court Of The University Of Edinburgh | Culture medium containing kinase inhibitors, and uses thereof |
| CN105861443A (zh) * | 2007-04-07 | 2016-08-17 | 怀特黑德生物医学研究所 | 体细胞重编程 |
| US9080145B2 (en) | 2007-07-01 | 2015-07-14 | Lifescan Corporation | Single pluripotent stem cell culture |
| EP2198012B1 (en) * | 2007-07-18 | 2014-12-31 | Cellartis AB | Cardiomyocyte-like cell clusters derived from hbs cells |
| CA3114827C (en) | 2007-07-31 | 2023-09-05 | Lifescan, Inc. | Differentiation of human embryonic stem cells to pancreatic endocrine |
| EP3078738B1 (en) | 2007-08-31 | 2020-05-20 | Whitehead Institute for Biomedical Research | Wnt pathway stimulation in reprogramming somatic cells |
| ES2690554T3 (es) * | 2008-03-17 | 2018-11-21 | The Scripps Research Institute | Enfoques químicos y genéticos combinados para la generación de células madre pluripotentes inducidas |
| AU2009234423A1 (en) * | 2008-04-07 | 2009-10-15 | Nupotential, Inc. | Reprogramming a cell by inducing a pluripotent gene through RNA interference |
| CN105671065A (zh) | 2008-06-13 | 2016-06-15 | 怀特黑德生物医学研究所 | 细胞编程和重编程 |
| AU2009267137A1 (en) | 2008-06-30 | 2010-01-07 | Centocor Ortho Biotech Inc. | Differentiation of pluripotent stem cells |
| US8735156B2 (en) | 2008-12-01 | 2014-05-27 | The Board Of Regents Of The University Of Texas System | Production and use of rat spermatogonial stem cell lines |
| ES2645869T3 (es) * | 2008-12-17 | 2017-12-11 | The Scripps Research Institute | Generación y mantenimiento de células madre |
| US20110088107A1 (en) * | 2009-04-24 | 2011-04-14 | Yaqub Hanna | Compositions and methods for deriving or culturing pluripotent cells |
| ES2638464T3 (es) * | 2009-10-16 | 2017-10-20 | The Scripps Research Institute | Inducción de células pluripotentes |
| CN102762717A (zh) * | 2009-12-01 | 2012-10-31 | 日本国立癌症研究中心 | 使用大鼠胚胎干细胞构建嵌合大鼠的方法 |
| WO2011081222A1 (ja) * | 2009-12-29 | 2011-07-07 | 武田薬品工業株式会社 | 膵ホルモン産生細胞の製造法 |
| AU2011235212B2 (en) | 2010-03-31 | 2014-07-31 | The Scripps Research Institute | Reprogramming cells |
| JPWO2011125948A1 (ja) * | 2010-04-02 | 2013-07-11 | 独立行政法人理化学研究所 | Es細胞の製造方法 |
| EP3399026B1 (en) | 2010-06-14 | 2024-06-26 | The Scripps Research Institute | Reprogramming of cells to a new fate |
| CN102344490B (zh) * | 2010-07-30 | 2014-03-05 | 中国科学院上海生命科学研究院 | 抗小鼠Stk40的多克隆抗体及其制备 |
| WO2012020845A1 (ja) * | 2010-08-09 | 2012-02-16 | 武田薬品工業株式会社 | 膵ホルモン産生細胞の製造法 |
| US10214722B2 (en) * | 2010-09-07 | 2019-02-26 | Technion Research & Development Foundation Limited | Methods for expanding and maintaining human pluripotent stem cells (PSCs) in an undifferentiated state in a single cell suspension culture |
| JP6090855B2 (ja) * | 2010-11-17 | 2017-03-08 | 国立大学法人京都大学 | 心筋細胞および/または心筋前駆細胞増殖剤ならびに心筋細胞および/または心筋前駆細胞の増殖方法 |
| CN106893692B (zh) | 2010-12-22 | 2021-11-26 | 菲特治疗公司 | 用于单细胞分选与增强ipsc重新编程的细胞培养平台 |
| EP2668286A4 (en) * | 2011-01-24 | 2015-07-01 | Univ Ben Gurion | METHOD FOR EVALUATING A MENTAL DISEASE |
| ES2902650T3 (es) | 2011-06-21 | 2022-03-29 | Novo Nordisk As | Inducción eficiente de endodermo definitivo a partir de células madre pluripotentes |
| HUE068728T2 (hu) | 2011-08-05 | 2025-01-28 | Regeneron Pharma | Humanizált univerzális könnyûláncú egerek |
| MX378871B (es) | 2011-12-20 | 2025-03-10 | Regeneron Pharma | Ratones con cadena ligera humanizada. |
| JP6275120B2 (ja) | 2012-04-25 | 2018-02-07 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. | 大きい標的化ベクターによるヌクレアーゼ媒介標的化 |
| JP6475172B2 (ja) | 2013-02-20 | 2019-02-27 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. | ラットの遺伝子組換え |
| EP3456831B1 (en) | 2013-04-16 | 2021-07-14 | Regeneron Pharmaceuticals, Inc. | Targeted modification of rat genome |
| WO2014197934A1 (en) | 2013-06-14 | 2014-12-18 | The University Of Queensland | Renal progenitor cells |
| MX388127B (es) | 2013-12-11 | 2025-03-19 | Regeneron Pharma | Metodos y composiciones para la modificacion dirigida de un genoma. |
| SG10201807292YA (en) | 2014-03-04 | 2018-09-27 | Fate Therapeutics Inc | Improved reprogramming methods and cell culture platforms |
| WO2015155738A2 (en) | 2014-04-09 | 2015-10-15 | Christopher Rudd | Use of gsk-3 inhibitors or activators which modulate pd-1 or t-bet expression to modulate t cell immunity |
| JP6652334B2 (ja) | 2014-05-31 | 2020-02-19 | Jcrファーマ株式会社 | ウリジンとn−アセチル−d−マンノサミンとを含有する培地 |
| BR112016028564A2 (pt) | 2014-06-06 | 2018-01-30 | Regeneron Pharma | método para modificar um locus-alvo em uma célula. |
| SG10201911411YA (en) | 2014-06-26 | 2020-02-27 | Regeneron Pharma | Methods and compositions for targeted genetic modifications and methods of use |
| CA3176380A1 (en) | 2014-11-21 | 2016-05-26 | Regeneron Pharmaceuticals, Inc. | Methods and compositions for targeted genetic modification using paired guide rnas |
| BR112017013104A2 (pt) | 2014-12-19 | 2018-05-15 | Regeneron Pharma | métodos para modificar um locus genômico alvo em uma célula, para intensificar a recombinação homóloga em um locus genômico alvo em uma célula e para produzir uma geração f0 de um animal não humano. |
| CA2981277A1 (en) * | 2015-03-30 | 2016-10-06 | Ajinomoto Co., Inc. | Human serum albumin-containing culture medium for growth of neural stem cells |
| AU2016338680B2 (en) | 2015-10-16 | 2022-11-17 | Fate Therapeutics, Inc. | Platform for the induction and maintenance of ground state pluripotency |
| MA45479A (fr) | 2016-04-14 | 2019-02-20 | Janssen Biotech Inc | Différenciation de cellules souches pluripotentes en cellules de l'endoderme de l'intestin moyen |
| JP2019537729A (ja) | 2016-09-28 | 2019-12-26 | オルガノボ インコーポレイテッド | アッセイにおける人工腎臓組織の使用 |
| WO2019208787A1 (ja) * | 2018-04-27 | 2019-10-31 | 株式会社カネカ | 原始腸管細胞の製造方法 |
| SG11202104941YA (en) * | 2018-11-21 | 2021-06-29 | Agency Science Tech & Res | Generation of mature kupffer cells |
| CN111238897B (zh) * | 2020-02-18 | 2023-03-28 | 上海市皮肤病医院 | 生物标本的处理方法与处理剂 |
| CN116096860A (zh) * | 2020-07-02 | 2023-05-09 | 阿塞尔塔有限公司 | 来自延迟胚胎的哺乳动物牲畜多能干细胞系 |
| EP4386082A4 (en) * | 2021-08-10 | 2025-08-20 | Kaneka Corp | PROCESS FOR THE PRODUCTION OF PLURIPOTENT STEM CELLS |
| CN115927166A (zh) * | 2022-12-06 | 2023-04-07 | 云南省第一人民医院 | 一种大鼠原始内胚层干细胞分离建系的方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9308271D0 (en) | 1993-04-21 | 1993-06-02 | Univ Edinburgh | Method of isolating and/or enriching and/or selectively propagating pluripotential animal cells and animals for use in said method |
| WO1995006716A1 (en) | 1993-08-30 | 1995-03-09 | Northwestern University | Rat pluripotent embryonic stem cells and method of obtaining and using same |
| EP0941310A1 (en) | 1996-10-11 | 1999-09-15 | THE TEXAS A&M UNIVERSITY SYSTEM | Methods for the generation of primordial germ cells and transgenic animal species |
| US6214795B1 (en) * | 1996-11-12 | 2001-04-10 | Praecis Pharmaceuticals, Inc. | Peptide compounds useful for modulating FGF receptor activity |
| EP0986635A4 (en) | 1997-01-10 | 2001-11-07 | Life Technologies Inc | SERUM SUBSTITUTE FOR EMBRYONIC STEM CELLS |
| WO1999027076A1 (en) * | 1997-11-25 | 1999-06-03 | Arc Genomic Research | Pluripotent embryonic stem cells and methods of obtaining them |
| GB9819912D0 (en) | 1998-09-11 | 1998-11-04 | Univ Edinburgh | Propagation and/or derivation of embryonic stem cells |
| US7455983B2 (en) * | 2000-01-11 | 2008-11-25 | Geron Corporation | Medium for growing human embryonic stem cells |
| US20020045260A1 (en) * | 2000-10-17 | 2002-04-18 | Shih-Chieh Hung | Method of isolating mesenchymal stem cells |
| JP2002176973A (ja) | 2000-12-14 | 2002-06-25 | Shigeo Saito | 哺乳動物胚性幹細胞とその樹立方法並びにその継代培養方法 |
| DE60301953T2 (de) | 2002-03-05 | 2006-07-27 | Artemis Pharmaceuticals Gmbh | Durch inzucht erzeugte von embryonalen stammzellen abgeleitete mäuse |
| GB0210539D0 (en) | 2002-05-08 | 2002-06-19 | Univ Edinburgh | Control of es cell self renewal and lineage specification, and medium therefor |
| US7338957B2 (en) | 2003-08-28 | 2008-03-04 | Irm Llc | Compounds and compositions as protein kinase inhibitors |
| KR101221302B1 (ko) * | 2003-12-23 | 2013-01-11 | 비아싸이트, 인크. | 완전 내배엽 |
| KR101386690B1 (ko) | 2004-03-04 | 2014-04-22 | 도쿠리츠교세이호진 고쿠리츠간켄큐센터 | 래트 배아 줄기 세포 |
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| US9074180B2 (en) | 2006-03-30 | 2015-07-07 | The University Court Of The University Of Edinburgh | Culture medium containing kinase inhibitors, and uses thereof |
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| EP2018167A4 (en) | 2006-05-15 | 2010-07-14 | Irm Llc | COMPOSITIONS AND METHODS AS INHIBITORS OF FGF RECEPTOR KINASES |
-
2006
- 2006-08-01 GB GBGB0615327.4A patent/GB0615327D0/en not_active Ceased
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2007
- 2007-01-10 GB GBGB0700479.9A patent/GB0700479D0/en not_active Ceased
- 2007-08-01 AU AU2007280216A patent/AU2007280216B2/en not_active Ceased
- 2007-08-01 WO PCT/GB2007/002913 patent/WO2008015418A2/en not_active Ceased
- 2007-08-01 US US11/832,317 patent/US8431395B2/en not_active Expired - Fee Related
- 2007-08-01 CN CN200780036720.1A patent/CN101657535B/zh not_active Expired - Fee Related
- 2007-08-01 GB GB0716426A patent/GB2451523B/en not_active Expired - Fee Related
- 2007-08-01 JP JP2009522328A patent/JP5456467B2/ja not_active Expired - Fee Related
- 2007-08-01 CN CN201410720584.XA patent/CN104531610A/zh active Pending
- 2007-08-01 EP EP07766403A patent/EP2049654A2/en not_active Withdrawn
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2013
- 2013-04-05 US US13/857,449 patent/US20130333058A1/en not_active Abandoned
- 2013-06-17 JP JP2013127052A patent/JP2013176400A/ja active Pending
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| Publication number | Publication date |
|---|---|
| WO2008015418A3 (en) | 2008-04-10 |
| EP2049654A2 (en) | 2009-04-22 |
| GB0716426D0 (en) | 2007-10-10 |
| CN101657535A (zh) | 2010-02-24 |
| GB0700479D0 (en) | 2007-02-21 |
| GB2451523B (en) | 2010-03-17 |
| CN104531610A (zh) | 2015-04-22 |
| JP5456467B2 (ja) | 2014-03-26 |
| AU2007280216B2 (en) | 2012-12-20 |
| US20130333058A1 (en) | 2013-12-12 |
| US8431395B2 (en) | 2013-04-30 |
| JP2009545302A (ja) | 2009-12-24 |
| AU2007280216A1 (en) | 2008-02-07 |
| CN101657535B (zh) | 2016-03-02 |
| GB2451523A (en) | 2009-02-04 |
| US20080066197A1 (en) | 2008-03-13 |
| WO2008015418A2 (en) | 2008-02-07 |
| JP2013176400A (ja) | 2013-09-09 |
| GB2451523A8 (en) | 2009-02-18 |
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