AU2007258335B2 - Methods and compositions for improving cognitive function - Google Patents

Methods and compositions for improving cognitive function Download PDF

Info

Publication number
AU2007258335B2
AU2007258335B2 AU2007258335A AU2007258335A AU2007258335B2 AU 2007258335 B2 AU2007258335 B2 AU 2007258335B2 AU 2007258335 A AU2007258335 A AU 2007258335A AU 2007258335 A AU2007258335 A AU 2007258335A AU 2007258335 B2 AU2007258335 B2 AU 2007258335B2
Authority
AU
Australia
Prior art keywords
compound
composition
cocoa
switch
sugar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2007258335A
Other languages
English (en)
Other versions
AU2007258335A1 (en
Inventor
Susan T. Francis
Stephen French
Amar P. Inamdar
Ian Andrew Macdonald
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mars Inc
Original Assignee
Mars Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mars Inc filed Critical Mars Inc
Publication of AU2007258335A1 publication Critical patent/AU2007258335A1/en
Application granted granted Critical
Publication of AU2007258335B2 publication Critical patent/AU2007258335B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G1/00—Cocoa; Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/30—Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/32—Cocoa products, e.g. chocolate; Substitutes therefor characterised by the composition containing organic or inorganic compounds
    • A23G1/48—Cocoa products, e.g. chocolate; Substitutes therefor characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds or extracts
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G1/00—Cocoa; Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/30—Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/56—Liquid products; Solid products in the form of powders, flakes or granules for making liquid products, e.g. for making chocolate milk, drinks and the products for their preparation, pastes for spreading or milk crumb
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G2200/00—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents
    • A23G2200/14—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents containing fruits, nuts, e.g. almonds, seeds, plants, plant extracts or essential oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Confectionery (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pyrane Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2007258335A 2006-06-15 2007-06-13 Methods and compositions for improving cognitive function Active AU2007258335B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81394806P 2006-06-15 2006-06-15
US60/813,948 2006-06-15
PCT/US2007/013820 WO2007146306A2 (en) 2006-06-15 2007-06-13 Methods and compositions for improving cognitive function

Publications (2)

Publication Number Publication Date
AU2007258335A1 AU2007258335A1 (en) 2007-12-21
AU2007258335B2 true AU2007258335B2 (en) 2013-11-14

Family

ID=38832498

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007258335A Active AU2007258335B2 (en) 2006-06-15 2007-06-13 Methods and compositions for improving cognitive function

Country Status (9)

Country Link
US (3) US9283203B2 (enExample)
EP (2) EP2034989A4 (enExample)
JP (1) JP5751753B2 (enExample)
CN (1) CN101505745A (enExample)
AU (1) AU2007258335B2 (enExample)
CA (1) CA2659099A1 (enExample)
IL (1) IL195787A (enExample)
RU (1) RU2496492C2 (enExample)
WO (1) WO2007146306A2 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7514107B2 (en) * 2002-03-21 2009-04-07 Mars, Incorporated Treatment of diseases involving defective gap junctional communication
AU2007258335B2 (en) 2006-06-15 2013-11-14 Mars Incorporated Methods and compositions for improving cognitive function
GB0719544D0 (en) * 2007-10-08 2007-11-14 Barry Callebaut Ag Cocoa extract and use thereof
GB0719545D0 (en) * 2007-10-08 2007-11-14 Barry Callebaut Ag Novel use of cocoa extract
GB0719542D0 (en) * 2007-10-08 2007-11-14 Barry Callebaut Ag Use of cocoa extract
CN101530410B (zh) * 2009-04-10 2010-12-29 浙江萧山医院 原花青素类化合物用于制备抗血管性痴呆产品的用途
JP2010275275A (ja) * 2009-06-01 2010-12-09 Ito En Ltd 集中力向上用組成物及び飲食物
AU2011254726B2 (en) 2010-05-19 2014-03-06 Upfield Europe B.V. Theobromine for increasing HDL-cholesterol
US8791699B2 (en) * 2010-06-01 2014-07-29 Children's Hospital Medical Center Simultaneous ASL/bold functional MRI
US9265458B2 (en) 2012-12-04 2016-02-23 Sync-Think, Inc. Application of smooth pursuit cognitive testing paradigms to clinical drug development
US20140180060A1 (en) * 2012-12-17 2014-06-26 Todd Parrish Methods and Systems for Automated Functional MRI in Clinical Applications
US20140255900A1 (en) * 2013-03-09 2014-09-11 University Of Georgia Research Foundation, Inc. Dual task mental deficiency assessment systems and methods
US9380976B2 (en) 2013-03-11 2016-07-05 Sync-Think, Inc. Optical neuroinformatics
WO2015089503A2 (en) * 2013-12-13 2015-06-18 Northwestern University Methods of treating brain disorders or identifying biomarkers related thereto
US20150216468A1 (en) * 2014-01-31 2015-08-06 Konica Minolta Laboratory U.S.A., Inc. Method and system for real-time insight detection using eeg signals
US20160158240A1 (en) * 2014-12-05 2016-06-09 The Hershey Company Compositions Containing Defined Caffeine and Theobromine Levels with Enhanced Cognitive Properties
US20160225087A1 (en) * 2015-01-29 2016-08-04 Imatchative, Inc. Preference assessment for decison alternatives
EP3638801A4 (en) 2017-07-26 2021-03-24 Yacyshyn, Vincent DISPOSAL OF POLYPHENOLS CONTAMINANTS FROM STARTING CHARGE POLYPHENOLS
RU2727757C2 (ru) * 2018-06-27 2020-07-23 Федеральное государственное бюджетное образовательное учреждение высшего образования "Саратовский государственный медицинский университет им. В.И. Разумовского" Министерства здравоохранения Российской Федерации Способ повышения запоминания визуальных образов
US11173187B2 (en) 2018-11-13 2021-11-16 Immortazyme Company Ltd. Concentrated oil-based polyphenol composition and a method of producing the oil-based polyphenol composition
JP7126300B1 (ja) * 2022-03-30 2022-08-26 金印株式会社 背外側前頭前野の血流増加剤、背外側前頭前野の活性化剤、背外側前頭前野の血流増加のための食品、及び背外側前頭前野を活性化させるための食品

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030180406A1 (en) * 2002-03-21 2003-09-25 Helmut Sies Treatment of diseases involving defective gap junctional communication
WO2005123096A2 (en) * 2004-06-14 2005-12-29 Mars, Incorporated Compositions and methods of use of dimer digallates
WO2006126895A2 (en) * 2005-05-23 2006-11-30 Mathias Alfons Everhard Frevel Cognitive abilities improving agent
AU2006263666A1 (en) * 2005-06-29 2007-01-04 Mars, Incorporated Thermally-processed cocoa products useful for vascular health improvement

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3158749B2 (ja) 1992-12-16 2001-04-23 ヤマハ株式会社 半導体装置
US5554645A (en) 1994-10-03 1996-09-10 Mars, Incorporated Antineoplastic cocoa extracts and methods for making and using the same
US6297273B1 (en) 1996-04-02 2001-10-02 Mars, Inc. Use of cocoa solids having high cocoa polyphenol content in tabletting compositions and capsule filling compositions
US6312753B1 (en) 1996-09-06 2001-11-06 Mars, Incorporated Cocoa components, edible products having enriched polyphenol content, methods of making same and medical uses
US6015913A (en) 1996-09-06 2000-01-18 Mars, Incorporated Method for producing fat and/or solids from cocoa beans
US6558713B2 (en) 1996-09-06 2003-05-06 Mars, Incorporated Health of a mammal by administering a composition containing at least one cocoa polyphenol ingredient
US20030017998A1 (en) * 1997-05-16 2003-01-23 Snow Alan D. Proanthocyanidins for the treatment of amyloid and alpha-synuclein diseases
US6207842B1 (en) 1997-10-09 2001-03-27 Mars Incorporated Process for preparing procyanidin(4-6 or 4-8) oligomers and their derivatives
US7011856B2 (en) * 1998-08-05 2006-03-14 Amino Up Chemical Co., Ltd. Composition for the treatment of symptoms and conditions associated with aging
US6156912A (en) 1999-04-09 2000-12-05 Mars, Incorporated 88, 66, and 68 catechin and epicatechin dimers and methods for their preparation
US7015338B1 (en) 1999-04-15 2006-03-21 Mars Incorporated Synthetic methods for preparing procyanidin oligomers
CA2395695A1 (en) * 1999-12-30 2001-07-12 Proteotech, Inc. Catechins and green tea extract for the treatment of amyloidosis in alzheimer's disease and other amyloidoses
US6627232B1 (en) 2000-06-09 2003-09-30 Mars Incorporated Method for extracting cocoa procyanidins
JP5290488B2 (ja) 2000-09-28 2013-09-18 プレジデント アンド フェロウズ オブ ハーバード カレッジ 酸化物、ケイ酸塩及びリン酸塩の気相成長
US6733797B1 (en) * 2000-11-15 2004-05-11 William K. Summers Neuroceutical for improving memory and cognitive abilities
US7585523B2 (en) * 2002-08-27 2009-09-08 Targeted Medical Pharma Composition and method to augment and sustain neurotransmitter production
CN1845750B (zh) * 2003-09-02 2014-05-07 尤尼根公司 用于预防及治疗认知衰退和年龄相关的记忆障碍的无取代b环类黄酮和黄烷混合物的组合物
AU2007258335B2 (en) * 2006-06-15 2013-11-14 Mars Incorporated Methods and compositions for improving cognitive function

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030180406A1 (en) * 2002-03-21 2003-09-25 Helmut Sies Treatment of diseases involving defective gap junctional communication
WO2005123096A2 (en) * 2004-06-14 2005-12-29 Mars, Incorporated Compositions and methods of use of dimer digallates
WO2006126895A2 (en) * 2005-05-23 2006-11-30 Mathias Alfons Everhard Frevel Cognitive abilities improving agent
AU2006263666A1 (en) * 2005-06-29 2007-01-04 Mars, Incorporated Thermally-processed cocoa products useful for vascular health improvement

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Williamson, G. et al. "Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies" Am. J. Clin Nutr. (2005) Vol.81 (suppl) pages 243S to 255S *

Also Published As

Publication number Publication date
IL195787A (en) 2015-09-24
US10695318B2 (en) 2020-06-30
WO2007146306A2 (en) 2007-12-21
EP2034989A2 (en) 2009-03-18
RU2496492C2 (ru) 2013-10-27
IL195787A0 (en) 2009-09-01
US10201522B2 (en) 2019-02-12
AU2007258335A1 (en) 2007-12-21
US20190209518A1 (en) 2019-07-11
RU2009101047A (ru) 2010-07-20
EP2034989A4 (en) 2011-02-16
JP5751753B2 (ja) 2015-07-22
US20160243076A1 (en) 2016-08-25
EP3744324A1 (en) 2020-12-02
JP2009539991A (ja) 2009-11-19
CA2659099A1 (en) 2007-12-21
WO2007146306A3 (en) 2008-11-13
US9283203B2 (en) 2016-03-15
US20080161386A1 (en) 2008-07-03
CN101505745A (zh) 2009-08-12

Similar Documents

Publication Publication Date Title
US10695318B2 (en) Methods and compositions for improving cognitive function
Massee et al. The acute and sub-chronic effects of cocoa flavanols on mood, cognitive and cardiovascular health in young healthy adults: a randomized, controlled trial
Scholey et al. Consumption of cocoa flavanols results in acute improvements in mood and cognitive performance during sustained mental effort
US8852656B2 (en) Sleep improvement composition
JP2009527487A (ja) ココア製品及び心血管状態を無糖ココアで処置する方法
US10130602B2 (en) Use of L-carnitine, salts and derivatives thereof for reducing or preventing fatigue and improving cognitive function
JP2010500973A (ja) アルギナーゼ濃度／活性の改善
JP7693243B2 (ja) 認知機能改善剤
CA2634127C (en) Skin protection and improvement
US20160158240A1 (en) Compositions Containing Defined Caffeine and Theobromine Levels with Enhanced Cognitive Properties
JP2021187785A (ja) 精神性疲労、意欲低下または眠気の改善剤
Cox et al. Polyphenols for brain and cognitive health
US20170354659A1 (en) Compositions containing defined caffeine and theobromine levels with enhanced cognitive properties
CN111480841A (zh) 具有神经营养功能的植物提取物，其制备方法和应用
Karatas et al. The Effects of Long-Term Cocoa Flavanols Intake on Cognitive Functions and Mood, and the Physiological Mechanisms Underlying These Effects: A Literature Review
WO2024262600A1 (ja) 認知資源の消費効率向上用組成物
Sasaki et al. The Effects of Dark Chocolate on Cognitive Performance during Cognitively Demanding Tasks
JP2020532580A (ja) キサントフィルおよびオメガ−３脂肪酸を含む組成物ならびにその使用法
Altınok et al. The acute effects of cocoa flavanols on cognitive control and response inhibition: A randomised crossover trial
Marashli The Difference in Caffeine Consumption among College Students at the Beginning and End of the Semester
Haskell et al. The Impact of Epicatechin on Human Cognition: The Ro
TW202345785A (zh) 背外側前額葉皮質的血流增加劑、背外側前額葉皮質的活化劑、用於增加背外側前額葉皮質的血流之食品及用於使背外側前額葉皮質活化之食品
Ahles et al. Aronia Melanocarpa Extract supplementation a< ects brain vascular function and cognitive performance: A randomized, double-blind, placebo-controlled, cross-over study in older adults with overweight or obesity
Srisuwan Prevention of Dementia Through Modifiable Risk Factors
KR20070046731A (ko) 뇌기능 개선용 조성물

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)