JP5751753B2 - 認知機能改善のための方法及び組成物 - Google Patents

認知機能改善のための方法及び組成物 Download PDF

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JP5751753B2
JP5751753B2 JP2009515463A JP2009515463A JP5751753B2 JP 5751753 B2 JP5751753 B2 JP 5751753B2 JP 2009515463 A JP2009515463 A JP 2009515463A JP 2009515463 A JP2009515463 A JP 2009515463A JP 5751753 B2 JP5751753 B2 JP 5751753B2
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compound
cocoa
agent
switch
cognitive
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Japanese (ja)
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JP2009539991A (ja
JP2009539991A5 (enExample
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フレンチ，ステファン
ピー イナムダー，アマー
ピー イナムダー，アマー
アンドルー マクドナルド，イアン
アンドルー マクドナルド，イアン
ティー フランシス，スーザン
ティー フランシス，スーザン
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Mars Inc
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Mars Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G1/00—Cocoa; Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/30—Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/32—Cocoa products, e.g. chocolate; Substitutes therefor characterised by the composition containing organic or inorganic compounds
    • A23G1/48—Cocoa products, e.g. chocolate; Substitutes therefor characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds or extracts
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G1/00—Cocoa; Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/30—Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/56—Liquid products; Solid products in the form of powders, flakes or granules for making liquid products, e.g. for making chocolate milk, drinks and the products for their preparation, pastes for spreading or milk crumb
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G2200/00—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents
    • A23G2200/14—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents containing fruits, nuts, e.g. almonds, seeds, plants, plant extracts or essential oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Confectionery (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pyrane Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2009515463A 2006-06-15 2007-06-13 認知機能改善のための方法及び組成物 Active JP5751753B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81394806P 2006-06-15 2006-06-15
US60/813,948 2006-06-15
PCT/US2007/013820 WO2007146306A2 (en) 2006-06-15 2007-06-13 Methods and compositions for improving cognitive function

Publications (3)

Publication Number Publication Date
JP2009539991A JP2009539991A (ja) 2009-11-19
JP2009539991A5 JP2009539991A5 (enExample) 2011-03-03
JP5751753B2 true JP5751753B2 (ja) 2015-07-22

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JP2009515463A Active JP5751753B2 (ja) 2006-06-15 2007-06-13 認知機能改善のための方法及び組成物

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US (3) US9283203B2 (enExample)
EP (2) EP2034989A4 (enExample)
JP (1) JP5751753B2 (enExample)
CN (1) CN101505745A (enExample)
AU (1) AU2007258335B2 (enExample)
CA (1) CA2659099A1 (enExample)
IL (1) IL195787A (enExample)
RU (1) RU2496492C2 (enExample)
WO (1) WO2007146306A2 (enExample)

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* Cited by examiner, † Cited by third party
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US7514107B2 (en) * 2002-03-21 2009-04-07 Mars, Incorporated Treatment of diseases involving defective gap junctional communication
AU2007258335B2 (en) 2006-06-15 2013-11-14 Mars Incorporated Methods and compositions for improving cognitive function
GB0719544D0 (en) * 2007-10-08 2007-11-14 Barry Callebaut Ag Cocoa extract and use thereof
GB0719545D0 (en) * 2007-10-08 2007-11-14 Barry Callebaut Ag Novel use of cocoa extract
GB0719542D0 (en) * 2007-10-08 2007-11-14 Barry Callebaut Ag Use of cocoa extract
CN101530410B (zh) * 2009-04-10 2010-12-29 浙江萧山医院 原花青素类化合物用于制备抗血管性痴呆产品的用途
JP2010275275A (ja) * 2009-06-01 2010-12-09 Ito En Ltd 集中力向上用組成物及び飲食物
AU2011254726B2 (en) 2010-05-19 2014-03-06 Upfield Europe B.V. Theobromine for increasing HDL-cholesterol
US8791699B2 (en) * 2010-06-01 2014-07-29 Children's Hospital Medical Center Simultaneous ASL/bold functional MRI
US9265458B2 (en) 2012-12-04 2016-02-23 Sync-Think, Inc. Application of smooth pursuit cognitive testing paradigms to clinical drug development
US20140180060A1 (en) * 2012-12-17 2014-06-26 Todd Parrish Methods and Systems for Automated Functional MRI in Clinical Applications
US20140255900A1 (en) * 2013-03-09 2014-09-11 University Of Georgia Research Foundation, Inc. Dual task mental deficiency assessment systems and methods
US9380976B2 (en) 2013-03-11 2016-07-05 Sync-Think, Inc. Optical neuroinformatics
WO2015089503A2 (en) * 2013-12-13 2015-06-18 Northwestern University Methods of treating brain disorders or identifying biomarkers related thereto
US20150216468A1 (en) * 2014-01-31 2015-08-06 Konica Minolta Laboratory U.S.A., Inc. Method and system for real-time insight detection using eeg signals
US20160158240A1 (en) * 2014-12-05 2016-06-09 The Hershey Company Compositions Containing Defined Caffeine and Theobromine Levels with Enhanced Cognitive Properties
US20160225087A1 (en) * 2015-01-29 2016-08-04 Imatchative, Inc. Preference assessment for decison alternatives
EP3638801A4 (en) 2017-07-26 2021-03-24 Yacyshyn, Vincent DISPOSAL OF POLYPHENOLS CONTAMINANTS FROM STARTING CHARGE POLYPHENOLS
RU2727757C2 (ru) * 2018-06-27 2020-07-23 Федеральное государственное бюджетное образовательное учреждение высшего образования "Саратовский государственный медицинский университет им. В.И. Разумовского" Министерства здравоохранения Российской Федерации Способ повышения запоминания визуальных образов
US11173187B2 (en) 2018-11-13 2021-11-16 Immortazyme Company Ltd. Concentrated oil-based polyphenol composition and a method of producing the oil-based polyphenol composition
JP7126300B1 (ja) * 2022-03-30 2022-08-26 金印株式会社 背外側前頭前野の血流増加剤、背外側前頭前野の活性化剤、背外側前頭前野の血流増加のための食品、及び背外側前頭前野を活性化させるための食品

Family Cites Families (22)

* Cited by examiner, † Cited by third party
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JP3158749B2 (ja) 1992-12-16 2001-04-23 ヤマハ株式会社 半導体装置
US5554645A (en) 1994-10-03 1996-09-10 Mars, Incorporated Antineoplastic cocoa extracts and methods for making and using the same
US6297273B1 (en) 1996-04-02 2001-10-02 Mars, Inc. Use of cocoa solids having high cocoa polyphenol content in tabletting compositions and capsule filling compositions
US6312753B1 (en) 1996-09-06 2001-11-06 Mars, Incorporated Cocoa components, edible products having enriched polyphenol content, methods of making same and medical uses
US6015913A (en) 1996-09-06 2000-01-18 Mars, Incorporated Method for producing fat and/or solids from cocoa beans
US6558713B2 (en) 1996-09-06 2003-05-06 Mars, Incorporated Health of a mammal by administering a composition containing at least one cocoa polyphenol ingredient
US20030017998A1 (en) * 1997-05-16 2003-01-23 Snow Alan D. Proanthocyanidins for the treatment of amyloid and alpha-synuclein diseases
US6207842B1 (en) 1997-10-09 2001-03-27 Mars Incorporated Process for preparing procyanidin(4-6 or 4-8) oligomers and their derivatives
US7011856B2 (en) * 1998-08-05 2006-03-14 Amino Up Chemical Co., Ltd. Composition for the treatment of symptoms and conditions associated with aging
US6156912A (en) 1999-04-09 2000-12-05 Mars, Incorporated 88, 66, and 68 catechin and epicatechin dimers and methods for their preparation
US7015338B1 (en) 1999-04-15 2006-03-21 Mars Incorporated Synthetic methods for preparing procyanidin oligomers
CA2395695A1 (en) * 1999-12-30 2001-07-12 Proteotech, Inc. Catechins and green tea extract for the treatment of amyloidosis in alzheimer's disease and other amyloidoses
US6627232B1 (en) 2000-06-09 2003-09-30 Mars Incorporated Method for extracting cocoa procyanidins
JP5290488B2 (ja) 2000-09-28 2013-09-18 プレジデント アンド フェロウズ オブ ハーバード カレッジ 酸化物、ケイ酸塩及びリン酸塩の気相成長
US6733797B1 (en) * 2000-11-15 2004-05-11 William K. Summers Neuroceutical for improving memory and cognitive abilities
US7514107B2 (en) * 2002-03-21 2009-04-07 Mars, Incorporated Treatment of diseases involving defective gap junctional communication
US7585523B2 (en) * 2002-08-27 2009-09-08 Targeted Medical Pharma Composition and method to augment and sustain neurotransmitter production
CN1845750B (zh) * 2003-09-02 2014-05-07 尤尼根公司 用于预防及治疗认知衰退和年龄相关的记忆障碍的无取代b环类黄酮和黄烷混合物的组合物
CA2569986A1 (en) * 2004-06-14 2005-12-29 Mars, Incorporated Compositions and methods of use of dimer digallates
NZ540257A (en) * 2005-05-23 2008-06-30 Mathias Alfons Everhard Frevel Cognitive abilities improving agent obtained from Pinus bark
EP1896442A2 (en) * 2005-06-29 2008-03-12 Mars, Incorporated Thermally-processed cocoa products useful for vascular health improvement
AU2007258335B2 (en) * 2006-06-15 2013-11-14 Mars Incorporated Methods and compositions for improving cognitive function

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Publication number Publication date
IL195787A (en) 2015-09-24
US10695318B2 (en) 2020-06-30
WO2007146306A2 (en) 2007-12-21
EP2034989A2 (en) 2009-03-18
RU2496492C2 (ru) 2013-10-27
IL195787A0 (en) 2009-09-01
US10201522B2 (en) 2019-02-12
AU2007258335A1 (en) 2007-12-21
US20190209518A1 (en) 2019-07-11
RU2009101047A (ru) 2010-07-20
EP2034989A4 (en) 2011-02-16
US20160243076A1 (en) 2016-08-25
EP3744324A1 (en) 2020-12-02
JP2009539991A (ja) 2009-11-19
CA2659099A1 (en) 2007-12-21
WO2007146306A3 (en) 2008-11-13
US9283203B2 (en) 2016-03-15
AU2007258335B2 (en) 2013-11-14
US20080161386A1 (en) 2008-07-03
CN101505745A (zh) 2009-08-12

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