JP2009539991A5 - - Google Patents
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- JP2009539991A5 JP2009539991A5 JP2009515463A JP2009515463A JP2009539991A5 JP 2009539991 A5 JP2009539991 A5 JP 2009539991A5 JP 2009515463 A JP2009515463 A JP 2009515463A JP 2009515463 A JP2009515463 A JP 2009515463A JP 2009539991 A5 JP2009539991 A5 JP 2009539991A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- composition according
- sugar
- compound
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 26
- 150000001875 compounds Chemical class 0.000 claims 8
- 239000000178 monomer Substances 0.000 claims 4
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 claims 3
- PFTAWBLQPZVEMU-ZFWWWQNUSA-N (+)-epicatechin Natural products C1([C@@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-ZFWWWQNUSA-N 0.000 claims 3
- PFTAWBLQPZVEMU-UKRRQHHQSA-N (-)-epicatechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-UKRRQHHQSA-N 0.000 claims 3
- ADRVNXBAWSRFAJ-UHFFFAOYSA-N catechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3ccc(O)c(O)c3 ADRVNXBAWSRFAJ-UHFFFAOYSA-N 0.000 claims 3
- 235000005487 catechin Nutrition 0.000 claims 3
- 229950001002 cianidanol Drugs 0.000 claims 3
- LPTRNLNOHUVQMS-UHFFFAOYSA-N epicatechin Natural products Cc1cc(O)cc2OC(C(O)Cc12)c1ccc(O)c(O)c1 LPTRNLNOHUVQMS-UHFFFAOYSA-N 0.000 claims 3
- 235000012734 epicatechin Nutrition 0.000 claims 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 2
- 230000017531 blood circulation Effects 0.000 claims 2
- 230000003920 cognitive function Effects 0.000 claims 2
- 229940074391 gallic acid Drugs 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 230000001965 increasing effect Effects 0.000 claims 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 125000001424 substituent group Chemical group 0.000 claims 2
- 241001465754 Metazoa Species 0.000 claims 1
- 244000299461 Theobroma cacao Species 0.000 claims 1
- 235000009470 Theobroma cacao Nutrition 0.000 claims 1
- 235000013361 beverage Nutrition 0.000 claims 1
- 229940119429 cocoa extract Drugs 0.000 claims 1
- 230000003930 cognitive ability Effects 0.000 claims 1
- 235000009508 confectionery Nutrition 0.000 claims 1
- 238000010276 construction Methods 0.000 claims 1
- 230000007423 decrease Effects 0.000 claims 1
- 230000007123 defense Effects 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81394806P | 2006-06-15 | 2006-06-15 | |
| US60/813,948 | 2006-06-15 | ||
| PCT/US2007/013820 WO2007146306A2 (en) | 2006-06-15 | 2007-06-13 | Methods and compositions for improving cognitive function |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009539991A JP2009539991A (ja) | 2009-11-19 |
| JP2009539991A5 true JP2009539991A5 (enExample) | 2011-03-03 |
| JP5751753B2 JP5751753B2 (ja) | 2015-07-22 |
Family
ID=38832498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009515463A Active JP5751753B2 (ja) | 2006-06-15 | 2007-06-13 | 認知機能改善のための方法及び組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US9283203B2 (enExample) |
| EP (2) | EP2034989A4 (enExample) |
| JP (1) | JP5751753B2 (enExample) |
| CN (1) | CN101505745A (enExample) |
| AU (1) | AU2007258335B2 (enExample) |
| CA (1) | CA2659099A1 (enExample) |
| IL (1) | IL195787A (enExample) |
| RU (1) | RU2496492C2 (enExample) |
| WO (1) | WO2007146306A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7514107B2 (en) * | 2002-03-21 | 2009-04-07 | Mars, Incorporated | Treatment of diseases involving defective gap junctional communication |
| AU2007258335B2 (en) | 2006-06-15 | 2013-11-14 | Mars Incorporated | Methods and compositions for improving cognitive function |
| GB0719544D0 (en) * | 2007-10-08 | 2007-11-14 | Barry Callebaut Ag | Cocoa extract and use thereof |
| GB0719545D0 (en) * | 2007-10-08 | 2007-11-14 | Barry Callebaut Ag | Novel use of cocoa extract |
| GB0719542D0 (en) * | 2007-10-08 | 2007-11-14 | Barry Callebaut Ag | Use of cocoa extract |
| CN101530410B (zh) * | 2009-04-10 | 2010-12-29 | 浙江萧山医院 | 原花青素类化合物用于制备抗血管性痴呆产品的用途 |
| JP2010275275A (ja) * | 2009-06-01 | 2010-12-09 | Ito En Ltd | 集中力向上用組成物及び飲食物 |
| AU2011254726B2 (en) | 2010-05-19 | 2014-03-06 | Upfield Europe B.V. | Theobromine for increasing HDL-cholesterol |
| US8791699B2 (en) * | 2010-06-01 | 2014-07-29 | Children's Hospital Medical Center | Simultaneous ASL/bold functional MRI |
| US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
| US20140180060A1 (en) * | 2012-12-17 | 2014-06-26 | Todd Parrish | Methods and Systems for Automated Functional MRI in Clinical Applications |
| US20140255900A1 (en) * | 2013-03-09 | 2014-09-11 | University Of Georgia Research Foundation, Inc. | Dual task mental deficiency assessment systems and methods |
| US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
| WO2015089503A2 (en) * | 2013-12-13 | 2015-06-18 | Northwestern University | Methods of treating brain disorders or identifying biomarkers related thereto |
| US20150216468A1 (en) * | 2014-01-31 | 2015-08-06 | Konica Minolta Laboratory U.S.A., Inc. | Method and system for real-time insight detection using eeg signals |
| US20160158240A1 (en) * | 2014-12-05 | 2016-06-09 | The Hershey Company | Compositions Containing Defined Caffeine and Theobromine Levels with Enhanced Cognitive Properties |
| US20160225087A1 (en) * | 2015-01-29 | 2016-08-04 | Imatchative, Inc. | Preference assessment for decison alternatives |
| EP3638801A4 (en) | 2017-07-26 | 2021-03-24 | Yacyshyn, Vincent | DISPOSAL OF POLYPHENOLS CONTAMINANTS FROM STARTING CHARGE POLYPHENOLS |
| RU2727757C2 (ru) * | 2018-06-27 | 2020-07-23 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Саратовский государственный медицинский университет им. В.И. Разумовского" Министерства здравоохранения Российской Федерации | Способ повышения запоминания визуальных образов |
| US11173187B2 (en) | 2018-11-13 | 2021-11-16 | Immortazyme Company Ltd. | Concentrated oil-based polyphenol composition and a method of producing the oil-based polyphenol composition |
| JP7126300B1 (ja) * | 2022-03-30 | 2022-08-26 | 金印株式会社 | 背外側前頭前野の血流増加剤、背外側前頭前野の活性化剤、背外側前頭前野の血流増加のための食品、及び背外側前頭前野を活性化させるための食品 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3158749B2 (ja) | 1992-12-16 | 2001-04-23 | ヤマハ株式会社 | 半導体装置 |
| US5554645A (en) | 1994-10-03 | 1996-09-10 | Mars, Incorporated | Antineoplastic cocoa extracts and methods for making and using the same |
| US6297273B1 (en) | 1996-04-02 | 2001-10-02 | Mars, Inc. | Use of cocoa solids having high cocoa polyphenol content in tabletting compositions and capsule filling compositions |
| US6312753B1 (en) | 1996-09-06 | 2001-11-06 | Mars, Incorporated | Cocoa components, edible products having enriched polyphenol content, methods of making same and medical uses |
| US6015913A (en) | 1996-09-06 | 2000-01-18 | Mars, Incorporated | Method for producing fat and/or solids from cocoa beans |
| US6558713B2 (en) | 1996-09-06 | 2003-05-06 | Mars, Incorporated | Health of a mammal by administering a composition containing at least one cocoa polyphenol ingredient |
| US20030017998A1 (en) * | 1997-05-16 | 2003-01-23 | Snow Alan D. | Proanthocyanidins for the treatment of amyloid and alpha-synuclein diseases |
| US6207842B1 (en) | 1997-10-09 | 2001-03-27 | Mars Incorporated | Process for preparing procyanidin(4-6 or 4-8) oligomers and their derivatives |
| US7011856B2 (en) * | 1998-08-05 | 2006-03-14 | Amino Up Chemical Co., Ltd. | Composition for the treatment of symptoms and conditions associated with aging |
| US6156912A (en) | 1999-04-09 | 2000-12-05 | Mars, Incorporated | 88, 66, and 68 catechin and epicatechin dimers and methods for their preparation |
| US7015338B1 (en) | 1999-04-15 | 2006-03-21 | Mars Incorporated | Synthetic methods for preparing procyanidin oligomers |
| CA2395695A1 (en) * | 1999-12-30 | 2001-07-12 | Proteotech, Inc. | Catechins and green tea extract for the treatment of amyloidosis in alzheimer's disease and other amyloidoses |
| US6627232B1 (en) | 2000-06-09 | 2003-09-30 | Mars Incorporated | Method for extracting cocoa procyanidins |
| JP5290488B2 (ja) | 2000-09-28 | 2013-09-18 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | 酸化物、ケイ酸塩及びリン酸塩の気相成長 |
| US6733797B1 (en) * | 2000-11-15 | 2004-05-11 | William K. Summers | Neuroceutical for improving memory and cognitive abilities |
| US7514107B2 (en) * | 2002-03-21 | 2009-04-07 | Mars, Incorporated | Treatment of diseases involving defective gap junctional communication |
| US7585523B2 (en) * | 2002-08-27 | 2009-09-08 | Targeted Medical Pharma | Composition and method to augment and sustain neurotransmitter production |
| CN1845750B (zh) * | 2003-09-02 | 2014-05-07 | 尤尼根公司 | 用于预防及治疗认知衰退和年龄相关的记忆障碍的无取代b环类黄酮和黄烷混合物的组合物 |
| CA2569986A1 (en) * | 2004-06-14 | 2005-12-29 | Mars, Incorporated | Compositions and methods of use of dimer digallates |
| NZ540257A (en) * | 2005-05-23 | 2008-06-30 | Mathias Alfons Everhard Frevel | Cognitive abilities improving agent obtained from Pinus bark |
| EP1896442A2 (en) * | 2005-06-29 | 2008-03-12 | Mars, Incorporated | Thermally-processed cocoa products useful for vascular health improvement |
| AU2007258335B2 (en) * | 2006-06-15 | 2013-11-14 | Mars Incorporated | Methods and compositions for improving cognitive function |
-
2007
- 2007-06-13 AU AU2007258335A patent/AU2007258335B2/en active Active
- 2007-06-13 WO PCT/US2007/013820 patent/WO2007146306A2/en not_active Ceased
- 2007-06-13 CA CA002659099A patent/CA2659099A1/en not_active Abandoned
- 2007-06-13 EP EP07809501A patent/EP2034989A4/en not_active Withdrawn
- 2007-06-13 EP EP20169605.1A patent/EP3744324A1/en active Pending
- 2007-06-13 CN CNA2007800304791A patent/CN101505745A/zh active Pending
- 2007-06-13 JP JP2009515463A patent/JP5751753B2/ja active Active
- 2007-06-13 RU RU2009101047/15A patent/RU2496492C2/ru active
- 2007-06-15 US US11/818,604 patent/US9283203B2/en active Active
-
2008
- 2008-12-08 IL IL195787A patent/IL195787A/en active IP Right Grant
-
2016
- 2016-02-03 US US15/014,255 patent/US10201522B2/en active Active
-
2019
- 2019-01-07 US US16/241,373 patent/US10695318B2/en active Active
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