AU2007238000B2 - Glucagon-like peptide 1(GLP-1) pharmaceutical formulations - Google Patents
Glucagon-like peptide 1(GLP-1) pharmaceutical formulations Download PDFInfo
- Publication number
- AU2007238000B2 AU2007238000B2 AU2007238000A AU2007238000A AU2007238000B2 AU 2007238000 B2 AU2007238000 B2 AU 2007238000B2 AU 2007238000 A AU2007238000 A AU 2007238000A AU 2007238000 A AU2007238000 A AU 2007238000A AU 2007238000 B2 AU2007238000 B2 AU 2007238000B2
- Authority
- AU
- Australia
- Prior art keywords
- glp
- fdkp
- diketopiperazine
- solution
- particle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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- 239000008194 pharmaceutical composition Substances 0.000 title abstract description 7
- GCYXWQUSHADNBF-AAEALURTSA-N preproglucagon 78-108 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 GCYXWQUSHADNBF-AAEALURTSA-N 0.000 title description 8
- DTHNMHAUYICORS-KTKZVXAJSA-N Glucagon-like peptide 1 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 DTHNMHAUYICORS-KTKZVXAJSA-N 0.000 claims abstract description 809
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Classifications
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Landscapes
- Health & Medical Sciences (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2013201640A AU2013201640A1 (en) | 2006-04-14 | 2013-03-19 | Glucagon-like peptide 1(GLP-1) pharmaceutical formulations |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74488206P | 2006-04-14 | 2006-04-14 | |
| US60/744,882 | 2006-04-14 | ||
| PCT/US2007/066728 WO2007121411A2 (en) | 2006-04-14 | 2007-04-16 | Glucagon-like peptide 1(glp-1) pharmaceutical formulations |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2013201640A Division AU2013201640A1 (en) | 2006-04-14 | 2013-03-19 | Glucagon-like peptide 1(GLP-1) pharmaceutical formulations |
Publications (2)
| Publication Number | Publication Date |
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| AU2007238000A1 AU2007238000A1 (en) | 2007-10-25 |
| AU2007238000B2 true AU2007238000B2 (en) | 2013-01-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| AU2007238000A Ceased AU2007238000B2 (en) | 2006-04-14 | 2007-04-16 | Glucagon-like peptide 1(GLP-1) pharmaceutical formulations |
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| EP (1) | EP2010155A2 (https=) |
| JP (3) | JP5415938B2 (https=) |
| KR (3) | KR20150042304A (https=) |
| CN (2) | CN104288756A (https=) |
| AU (1) | AU2007238000B2 (https=) |
| BR (1) | BRPI0709964A2 (https=) |
| CA (1) | CA2646400A1 (https=) |
| HK (1) | HK1206241A1 (https=) |
| MX (1) | MX2008013216A (https=) |
| RU (3) | RU2409349C2 (https=) |
| WO (1) | WO2007121411A2 (https=) |
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| KR102584844B1 (ko) | 2009-06-12 | 2023-10-04 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
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| CN102985125A (zh) | 2010-06-21 | 2013-03-20 | 曼金德公司 | 干粉药物输送系统和方法 |
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| WO2015086728A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Exendin-4 peptide analogues as dual glp-1/gip receptor agonists |
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| AR105284A1 (es) | 2015-07-10 | 2017-09-20 | Sanofi Sa | Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón |
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- 2007-04-16 CA CA002646400A patent/CA2646400A1/en active Pending
- 2007-04-16 WO PCT/US2007/066728 patent/WO2007121411A2/en not_active Ceased
- 2007-04-16 KR KR1020157008571A patent/KR20150042304A/ko not_active Ceased
- 2007-04-16 CN CN201410514033.8A patent/CN104288756A/zh active Pending
- 2007-04-16 BR BRPI0709964-9A patent/BRPI0709964A2/pt not_active IP Right Cessation
- 2007-04-16 KR KR1020087027774A patent/KR101438839B1/ko active Active
- 2007-04-16 AU AU2007238000A patent/AU2007238000B2/en not_active Ceased
- 2007-04-16 JP JP2009505655A patent/JP5415938B2/ja not_active Expired - Fee Related
- 2007-04-16 EP EP20070760728 patent/EP2010155A2/en not_active Withdrawn
- 2007-04-16 CN CNA200780013424XA patent/CN101453988A/zh active Pending
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2014
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2015
- 2015-07-16 HK HK15106772.4A patent/HK1206241A1/xx unknown
- 2015-11-30 JP JP2015233125A patent/JP2016104736A/ja active Pending
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| WO2001000654A2 (en) * | 1999-06-29 | 2001-01-04 | Pharmaceutical Discovery Corporation | Purification and stabilization of peptide and proteins in pharmaceutical agents |
| WO2002098348A2 (en) * | 2001-06-01 | 2002-12-12 | Eli Lilly And Company | Glp-1 formulations with protracted time action |
| US20040038865A1 (en) * | 2002-08-01 | 2004-02-26 | Mannkind Corporation | Cell transport compositions and uses thereof |
| WO2007033316A2 (en) * | 2005-09-14 | 2007-03-22 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007121411A3 (en) | 2007-12-13 |
| JP5415938B2 (ja) | 2014-02-12 |
| RU2409349C2 (ru) | 2011-01-20 |
| WO2007121411A2 (en) | 2007-10-25 |
| RU2008144965A (ru) | 2010-05-20 |
| KR101438839B1 (ko) | 2014-10-02 |
| KR20150042304A (ko) | 2015-04-20 |
| KR20140072138A (ko) | 2014-06-12 |
| RU2542500C2 (ru) | 2015-02-20 |
| RU2014152320A (ru) | 2016-07-20 |
| CN104288756A (zh) | 2015-01-21 |
| KR101558829B1 (ko) | 2015-10-08 |
| EP2010155A2 (en) | 2009-01-07 |
| BRPI0709964A2 (pt) | 2011-08-02 |
| KR20080111533A (ko) | 2008-12-23 |
| CA2646400A1 (en) | 2007-10-25 |
| JP5898156B2 (ja) | 2016-04-06 |
| RU2010137392A (ru) | 2012-03-20 |
| CN101453988A (zh) | 2009-06-10 |
| AU2007238000A1 (en) | 2007-10-25 |
| HK1206241A1 (en) | 2016-01-08 |
| JP2014043445A (ja) | 2014-03-13 |
| MX2008013216A (es) | 2008-10-27 |
| JP2016104736A (ja) | 2016-06-09 |
| JP2009533476A (ja) | 2009-09-17 |
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