AU2007234917B2 - Renin inhibitors for the treatment of hypertension - Google Patents

Renin inhibitors for the treatment of hypertension Download PDF

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Publication number
AU2007234917B2
AU2007234917B2 AU2007234917A AU2007234917A AU2007234917B2 AU 2007234917 B2 AU2007234917 B2 AU 2007234917B2 AU 2007234917 A AU2007234917 A AU 2007234917A AU 2007234917 A AU2007234917 A AU 2007234917A AU 2007234917 B2 AU2007234917 B2 AU 2007234917B2
Authority
AU
Australia
Prior art keywords
discontinuation
weeks
hypertension
blood pressure
days
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2007234917A
Other languages
English (en)
Other versions
AU2007234917A1 (en
Inventor
Andrew Satlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38420678&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2007234917(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Publication of AU2007234917A1 publication Critical patent/AU2007234917A1/en
Application granted granted Critical
Publication of AU2007234917B2 publication Critical patent/AU2007234917B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A61K31/175—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2007234917A 2006-04-03 2007-03-30 Renin inhibitors for the treatment of hypertension Ceased AU2007234917B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78884206P 2006-04-03 2006-04-03
US60/788,842 2006-04-03
PCT/US2007/065564 WO2007118023A1 (en) 2006-04-03 2007-03-30 Renin inhibitors for the treatment of hypertension

Publications (2)

Publication Number Publication Date
AU2007234917A1 AU2007234917A1 (en) 2007-10-18
AU2007234917B2 true AU2007234917B2 (en) 2011-05-12

Family

ID=38420678

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007234917A Ceased AU2007234917B2 (en) 2006-04-03 2007-03-30 Renin inhibitors for the treatment of hypertension

Country Status (20)

Country Link
US (1) US20090062395A1 (enExample)
EP (1) EP2004167A1 (enExample)
JP (1) JP2009532494A (enExample)
KR (1) KR20080108515A (enExample)
CN (1) CN101415413A (enExample)
AU (1) AU2007234917B2 (enExample)
BR (1) BRPI0710095A2 (enExample)
CA (1) CA2645260A1 (enExample)
CL (1) CL2007000912A1 (enExample)
IL (1) IL193905A0 (enExample)
MA (1) MA30387B1 (enExample)
MX (1) MX2008012729A (enExample)
NO (1) NO20084625L (enExample)
NZ (1) NZ571251A (enExample)
RU (1) RU2008143055A (enExample)
SG (1) SG170830A1 (enExample)
TN (1) TNSN08383A1 (enExample)
TW (1) TW200806283A (enExample)
WO (1) WO2007118023A1 (enExample)
ZA (1) ZA200807615B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009087116A1 (en) * 2008-01-11 2009-07-16 Novartis Ag Use of spp100 for the treatment of acute mi
CN102212012A (zh) * 2010-04-12 2011-10-12 上海源力生物技术有限公司 一种合成阿利克伦的中间体及其制备方法
EP2768971A1 (en) 2011-10-20 2014-08-27 Institut National de la Santé et de la Recherche Médicale (INSERM) Methods for the detection and the treatment of cardiac remodeling
AU2020259450A1 (en) * 2019-04-18 2021-11-18 EyePoint Pharmaceuticals, Inc. Methods of treating hypertension with activators of Tie-2

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0678503B1 (de) * 1994-04-18 1999-09-01 Novartis AG Delta-Amino-gamma-hydroxy-omega-aryl-alkansäureamide mit Enzym-, insbesondere Renin-hemmenden Eigenschaften

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5659065A (en) * 1994-04-18 1997-08-19 Novartis Corporation Alpha-aminoalkanoic acids and reduction products
US5606078A (en) * 1994-04-18 1997-02-25 Ciba-Geigy Corporation 3,5-Disubstituted tetrahydrofuran-2-ones
JP2005537822A (ja) * 2002-06-28 2005-12-15 ノバルティス アクチエンゲゼルシャフト 有機化合物の使用
US20040266743A1 (en) * 2003-05-09 2004-12-30 Pharmacia Corporation Combination of an aldosterone receptor antagonist and a renin inhibitor
WO2005037317A2 (en) * 2003-10-17 2005-04-28 Cornell Research Foundation, Inc. Mast cell-derived renin
PE20142101A1 (es) * 2004-03-17 2014-12-27 Novartis Ag Composiciones farmaceuticas de aliskiren
ATE401913T1 (de) * 2004-09-27 2008-08-15 Pantarhei Bioscience Bv Behandlung oder prävention von unplanmässigen blutungen bei frauen unter progestogenhaltiger medikation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0678503B1 (de) * 1994-04-18 1999-09-01 Novartis AG Delta-Amino-gamma-hydroxy-omega-aryl-alkansäureamide mit Enzym-, insbesondere Renin-hemmenden Eigenschaften

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
MEALEY, N. Drugs of the Future. 2001. Vol.26(12): 1139-1148 *
NUSSBERGER, J et al. Hypertension. 2002. Vol.39: 1-8 *
STANTON et al. Hypertension. 2003. Vol.42(6): 1137-1143 *
WOOD et al. Biochemical and Biophysical Research Communications. 2003. Vol.308(4):698-705 *
WOOD, J. Journal of Hypertension. 2005. Vol.23(2): 417-426 *

Also Published As

Publication number Publication date
BRPI0710095A2 (pt) 2011-08-02
IL193905A0 (en) 2009-08-03
RU2008143055A (ru) 2010-05-10
NZ571251A (en) 2011-12-22
AU2007234917A1 (en) 2007-10-18
CL2007000912A1 (es) 2008-03-14
SG170830A1 (en) 2011-05-30
CA2645260A1 (en) 2007-10-18
CN101415413A (zh) 2009-04-22
TW200806283A (en) 2008-02-01
NO20084625L (no) 2008-11-03
MA30387B1 (fr) 2009-05-04
MX2008012729A (es) 2008-10-14
EP2004167A1 (en) 2008-12-24
ZA200807615B (en) 2009-10-28
WO2007118023A1 (en) 2007-10-18
US20090062395A1 (en) 2009-03-05
KR20080108515A (ko) 2008-12-15
JP2009532494A (ja) 2009-09-10
TNSN08383A1 (en) 2009-12-29

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired