JP2009532494A - 高血圧処置のためのレニン阻害剤 - Google Patents

高血圧処置のためのレニン阻害剤 Download PDF

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Publication number
JP2009532494A
JP2009532494A JP2009504386A JP2009504386A JP2009532494A JP 2009532494 A JP2009532494 A JP 2009532494A JP 2009504386 A JP2009504386 A JP 2009504386A JP 2009504386 A JP2009504386 A JP 2009504386A JP 2009532494 A JP2009532494 A JP 2009532494A
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Japan
Prior art keywords
renin inhibitor
hypertension
discontinuation
blood pressure
administration
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Pending
Application number
JP2009504386A
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English (en)
Japanese (ja)
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JP2009532494A5 (enExample
Inventor
アンドリュー・サットリン
Original Assignee
ノバルティス アクチエンゲゼルシャフト
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38420678&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2009532494(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ノバルティス アクチエンゲゼルシャフト filed Critical ノバルティス アクチエンゲゼルシャフト
Publication of JP2009532494A publication Critical patent/JP2009532494A/ja
Publication of JP2009532494A5 publication Critical patent/JP2009532494A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A61K31/175—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2009504386A 2006-04-03 2007-03-30 高血圧処置のためのレニン阻害剤 Pending JP2009532494A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78884206P 2006-04-03 2006-04-03
PCT/US2007/065564 WO2007118023A1 (en) 2006-04-03 2007-03-30 Renin inhibitors for the treatment of hypertension

Publications (2)

Publication Number Publication Date
JP2009532494A true JP2009532494A (ja) 2009-09-10
JP2009532494A5 JP2009532494A5 (enExample) 2010-04-30

Family

ID=38420678

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009504386A Pending JP2009532494A (ja) 2006-04-03 2007-03-30 高血圧処置のためのレニン阻害剤

Country Status (20)

Country Link
US (1) US20090062395A1 (enExample)
EP (1) EP2004167A1 (enExample)
JP (1) JP2009532494A (enExample)
KR (1) KR20080108515A (enExample)
CN (1) CN101415413A (enExample)
AU (1) AU2007234917B2 (enExample)
BR (1) BRPI0710095A2 (enExample)
CA (1) CA2645260A1 (enExample)
CL (1) CL2007000912A1 (enExample)
IL (1) IL193905A0 (enExample)
MA (1) MA30387B1 (enExample)
MX (1) MX2008012729A (enExample)
NO (1) NO20084625L (enExample)
NZ (1) NZ571251A (enExample)
RU (1) RU2008143055A (enExample)
SG (1) SG170830A1 (enExample)
TN (1) TNSN08383A1 (enExample)
TW (1) TW200806283A (enExample)
WO (1) WO2007118023A1 (enExample)
ZA (1) ZA200807615B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009087116A1 (en) * 2008-01-11 2009-07-16 Novartis Ag Use of spp100 for the treatment of acute mi
CN102212012A (zh) * 2010-04-12 2011-10-12 上海源力生物技术有限公司 一种合成阿利克伦的中间体及其制备方法
EP2768971A1 (en) 2011-10-20 2014-08-27 Institut National de la Santé et de la Recherche Médicale (INSERM) Methods for the detection and the treatment of cardiac remodeling
AU2020259450A1 (en) * 2019-04-18 2021-11-18 EyePoint Pharmaceuticals, Inc. Methods of treating hypertension with activators of Tie-2

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005089729A2 (en) * 2004-03-17 2005-09-29 Novartis Ag Galenic formulations of organic compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5659065A (en) * 1994-04-18 1997-08-19 Novartis Corporation Alpha-aminoalkanoic acids and reduction products
MY119161A (en) * 1994-04-18 2005-04-30 Novartis Ag Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities
US5606078A (en) * 1994-04-18 1997-02-25 Ciba-Geigy Corporation 3,5-Disubstituted tetrahydrofuran-2-ones
JP2005537822A (ja) * 2002-06-28 2005-12-15 ノバルティス アクチエンゲゼルシャフト 有機化合物の使用
US20040266743A1 (en) * 2003-05-09 2004-12-30 Pharmacia Corporation Combination of an aldosterone receptor antagonist and a renin inhibitor
WO2005037317A2 (en) * 2003-10-17 2005-04-28 Cornell Research Foundation, Inc. Mast cell-derived renin
ES2310293T3 (es) * 2004-09-27 2009-01-01 Pantarhei Bioscience B.V. Tratamiento o prevencion de sangrados no programados en mujeres bajo medicacion que contiene progestogeno.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005089729A2 (en) * 2004-03-17 2005-09-29 Novartis Ag Galenic formulations of organic compounds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6012022283; Ｈｙｐｅｒｔｅｎｓｉｏｎ ｖｏｌ．４２, 2003, ｐ．１１３７-１１４３ *

Also Published As

Publication number Publication date
US20090062395A1 (en) 2009-03-05
MX2008012729A (es) 2008-10-14
MA30387B1 (fr) 2009-05-04
AU2007234917A1 (en) 2007-10-18
NO20084625L (no) 2008-11-03
IL193905A0 (en) 2009-08-03
EP2004167A1 (en) 2008-12-24
CL2007000912A1 (es) 2008-03-14
TW200806283A (en) 2008-02-01
KR20080108515A (ko) 2008-12-15
SG170830A1 (en) 2011-05-30
BRPI0710095A2 (pt) 2011-08-02
WO2007118023A1 (en) 2007-10-18
AU2007234917B2 (en) 2011-05-12
CA2645260A1 (en) 2007-10-18
NZ571251A (en) 2011-12-22
ZA200807615B (en) 2009-10-28
TNSN08383A1 (en) 2009-12-29
CN101415413A (zh) 2009-04-22
RU2008143055A (ru) 2010-05-10

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