AU2007227557A1 - Pyrazolo[1,5-a]pyrimidine derivatives and methods of use thereof - Google Patents

Pyrazolo[1,5-a]pyrimidine derivatives and methods of use thereof Download PDF

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Publication number
AU2007227557A1
AU2007227557A1 AU2007227557A AU2007227557A AU2007227557A1 AU 2007227557 A1 AU2007227557 A1 AU 2007227557A1 AU 2007227557 A AU2007227557 A AU 2007227557A AU 2007227557 A AU2007227557 A AU 2007227557A AU 2007227557 A1 AU2007227557 A1 AU 2007227557A1
Authority
AU
Australia
Prior art keywords
phenyl
trifluoromethyl
pyrazolo
benzamide
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2007227557A
Other languages
English (en)
Inventor
Dan Maarten Berger
Gregory M. Ciszewski
George Diamantidis
Ariamala Gopalsamy
Darrin William Hopper
Kyung-Hee Kim
Jeremy I. Levin
Zhong Li
Dennis William Powell
Edward James Salaski
Mengxiao Shi
Nancy Torres
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Publication of AU2007227557A1 publication Critical patent/AU2007227557A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2007227557A 2006-03-17 2007-03-15 Pyrazolo[1,5-a]pyrimidine derivatives and methods of use thereof Abandoned AU2007227557A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78363106P 2006-03-17 2006-03-17
US60/783,631 2006-03-17
PCT/US2007/006539 WO2007109093A2 (en) 2006-03-17 2007-03-15 Pyrazolo[1,5-a]pyrimidine derivatives and methods of use thereof

Publications (1)

Publication Number Publication Date
AU2007227557A1 true AU2007227557A1 (en) 2007-09-27

Family

ID=38522947

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007227557A Abandoned AU2007227557A1 (en) 2006-03-17 2007-03-15 Pyrazolo[1,5-a]pyrimidine derivatives and methods of use thereof

Country Status (9)

Country Link
US (1) US20070219186A1 (https=)
EP (1) EP1996594A2 (https=)
JP (1) JP2009530296A (https=)
CN (1) CN101405289A (https=)
AU (1) AU2007227557A1 (https=)
BR (1) BRPI0708813A2 (https=)
CA (1) CA2643968A1 (https=)
MX (1) MX2008011853A (https=)
WO (1) WO2007109093A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009108827A1 (en) * 2008-02-29 2009-09-03 Wyeth Fused tricyclic pyrazolo[1, 5-a]pyrimidines, methods for preparation and uses thereof
US20100029657A1 (en) * 2008-02-29 2010-02-04 Wyeth Bridged, Bicyclic Heterocyclic or Spiro Bicyclic Heterocyclic Derivatives of Pyrazolo[1, 5-A]Pyrimidines, Methods for Preparation and Uses Thereof
EP2346335B1 (en) * 2008-09-24 2018-11-14 Basf Se Pyrazole compounds for controlling invertebrate pests
CA2763589A1 (en) * 2009-05-28 2010-12-02 President And Fellows Of Harvard College N,n'-diarylurea compounds and n,n'-diarylthiourea compounds as inhibitors of translation initiation
WO2014111037A1 (zh) * 2013-01-18 2014-07-24 上海昀怡健康管理咨询有限公司 五元并六元杂环化合物、其制备方法、药物组合物和应用
US9242969B2 (en) * 2013-03-14 2016-01-26 Novartis Ag Biaryl amide compounds as kinase inhibitors
JP6832430B2 (ja) 2016-08-31 2021-02-24 アジオス ファーマシューティカルズ， インコーポレイテッド 細胞代謝過程の阻害剤
CN111542515B (zh) * 2017-10-30 2023-12-05 科罗拉多州立大学董事会法人团体 Toll样受体8(tlr8)特异性拮抗剂及其制备方法和用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4626538A (en) * 1983-06-23 1986-12-02 American Cyanamid Company [7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidines
US5219857A (en) * 1986-10-16 1993-06-15 American Cyanamid Company Method of treating cognitive and related neural behavioral problems
US5126340A (en) * 1986-10-16 1992-06-30 American Cyanamid Company 4-[(substituted)alkylcarbonyl]-4,5-dihydro and -4,5,6,7-tetrahydro-7-[(substituted)-phenyl]pyrazolo[1,5-a]pyrimidine-3-carbonitriles
US4963553A (en) * 1986-10-16 1990-10-16 American Cyanamid Co. 4-[(substituted) alkylcarbonyl]-4,5-dihydro- and -4,5,6,7-tetrahydro-7-[(substituted)phenyl]pyrazolo[1,5-a]pyrimidines
US4847256A (en) * 1986-10-16 1989-07-11 American Cyanamid Company 4,5-dihydro and 4,5,6,7-tetrahydropyrazolo(1,5-A)-pyrimidines
US5013737A (en) * 1988-02-22 1991-05-07 American Cyanamid Company 2,4,8-Trisubstituted-3H,6H-1,4,5A,8A-tetraazaacenaphtylene-3,5-(4H)-diones and 2,4-8-trisubstituted-4,5-dihydro-5-thioxo-3H,6H-1,4,5A,8A-tetrazaacenaphthylen-3-ones
US4916137A (en) * 1988-02-22 1990-04-10 American Cyanamid Company 5-(Substituted-amino)-8-(phenyl or substituted-phenyl)-3H,6H-1,4,5A,8A-tetraazaacenaphthylen-3-ones and treatment of neural behavior disorders
US20070179161A1 (en) * 2003-03-31 2007-08-02 Vernalis (Cambridge) Limited. Pyrazolopyrimidine compounds and their use in medicine
ES2222813B1 (es) * 2003-07-24 2005-12-16 Ferrer Internacional, S.A. N-(3-(3-sustituidas-pirazolo(1,5-a)pirimidin-7-il)-fenil)-sulfonamidas y composiciones y metodos relacionados.
WO2006033796A1 (en) * 2004-09-17 2006-03-30 Wyeth SUBSTITUTED PYRAZOLO [1,5-a] PYRIMIDINES AND PROCESS FOR MAKING SAME
WO2006033795A2 (en) * 2004-09-17 2006-03-30 Wyeth Substituted pyrazolo [1, 5-a] pyrimidines for inhibiting abnormal cell growth
EP1736475A1 (en) * 2005-06-21 2006-12-27 Ferrer Internacional, S.A. Halogenated pyrazolo[1,5-a]pyrimidines, processes, uses, compositions and intermediates

Also Published As

Publication number Publication date
EP1996594A2 (en) 2008-12-03
US20070219186A1 (en) 2007-09-20
CA2643968A1 (en) 2007-09-27
MX2008011853A (es) 2008-09-29
WO2007109093A2 (en) 2007-09-27
JP2009530296A (ja) 2009-08-27
CN101405289A (zh) 2009-04-08
WO2007109093A3 (en) 2008-01-24
BRPI0708813A2 (pt) 2011-05-24

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period