MX2008011853A - Derivados de pirazolo[1,5-a]pirimidina y sus metodos de uso. - Google Patents

Derivados de pirazolo[1,5-a]pirimidina y sus metodos de uso.

Info

Publication number
MX2008011853A
MX2008011853A MX2008011853A MX2008011853A MX2008011853A MX 2008011853 A MX2008011853 A MX 2008011853A MX 2008011853 A MX2008011853 A MX 2008011853A MX 2008011853 A MX2008011853 A MX 2008011853A MX 2008011853 A MX2008011853 A MX 2008011853A
Authority
MX
Mexico
Prior art keywords
phenyl
trifluoromethyl
pyrazolo
amino
pyrimidin
Prior art date
Application number
MX2008011853A
Other languages
English (en)
Spanish (es)
Inventor
Dan Maarten Berger
Ariamala Gopalsamy
George Diamantidis
Darrin William Hopper
Zhong Li
Dennis William Powell
Mengxiao Shi
Gregory M Ciszewski
Jeremy I Levin
Kyung-Hee Kim
Edward James Salaski
Nancy Torres
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of MX2008011853A publication Critical patent/MX2008011853A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX2008011853A 2006-03-17 2007-03-15 Derivados de pirazolo[1,5-a]pirimidina y sus metodos de uso. MX2008011853A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78363106P 2006-03-17 2006-03-17
PCT/US2007/006539 WO2007109093A2 (en) 2006-03-17 2007-03-15 Pyrazolo[1,5-a]pyrimidine derivatives and methods of use thereof

Publications (1)

Publication Number Publication Date
MX2008011853A true MX2008011853A (es) 2008-09-29

Family

ID=38522947

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008011853A MX2008011853A (es) 2006-03-17 2007-03-15 Derivados de pirazolo[1,5-a]pirimidina y sus metodos de uso.

Country Status (9)

Country Link
US (1) US20070219186A1 (https=)
EP (1) EP1996594A2 (https=)
JP (1) JP2009530296A (https=)
CN (1) CN101405289A (https=)
AU (1) AU2007227557A1 (https=)
BR (1) BRPI0708813A2 (https=)
CA (1) CA2643968A1 (https=)
MX (1) MX2008011853A (https=)
WO (1) WO2007109093A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100029657A1 (en) * 2008-02-29 2010-02-04 Wyeth Bridged, Bicyclic Heterocyclic or Spiro Bicyclic Heterocyclic Derivatives of Pyrazolo[1, 5-A]Pyrimidines, Methods for Preparation and Uses Thereof
WO2009108827A1 (en) * 2008-02-29 2009-09-03 Wyeth Fused tricyclic pyrazolo[1, 5-a]pyrimidines, methods for preparation and uses thereof
CN102223798A (zh) * 2008-09-24 2011-10-19 巴斯夫欧洲公司 用于防治无脊椎动物害虫的吡唑化合物
WO2010138820A2 (en) * 2009-05-28 2010-12-02 President And Fellows Of Harvard College N,n-diarylurea compounds and n,n'-diarylthiourea compounds as inhibitors of translation initiation
US9745320B2 (en) 2013-01-18 2017-08-29 Guangzhou Maxinovel Pharmaceuticals Co., Ltd. Five-and-six-membered heterocyclic compound, and preparation method, pharmaceutical composition and use thereof
US9242969B2 (en) * 2013-03-14 2016-01-26 Novartis Ag Biaryl amide compounds as kinase inhibitors
CR20190157A (es) 2016-08-31 2019-08-13 Agios Pharmaceuticals Inc Inhibidores de procesos metabólicos celulares
CN117659025A (zh) * 2017-10-30 2024-03-08 科罗拉多州立大学董事会法人团体 Toll样受体8（tlr8）特异性拮抗剂及其制备方法和用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4626538A (en) * 1983-06-23 1986-12-02 American Cyanamid Company [7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidines
US5219857A (en) * 1986-10-16 1993-06-15 American Cyanamid Company Method of treating cognitive and related neural behavioral problems
US4847256A (en) * 1986-10-16 1989-07-11 American Cyanamid Company 4,5-dihydro and 4,5,6,7-tetrahydropyrazolo(1,5-A)-pyrimidines
US5126340A (en) * 1986-10-16 1992-06-30 American Cyanamid Company 4-[(substituted)alkylcarbonyl]-4,5-dihydro and -4,5,6,7-tetrahydro-7-[(substituted)-phenyl]pyrazolo[1,5-a]pyrimidine-3-carbonitriles
US4963553A (en) * 1986-10-16 1990-10-16 American Cyanamid Co. 4-[(substituted) alkylcarbonyl]-4,5-dihydro- and -4,5,6,7-tetrahydro-7-[(substituted)phenyl]pyrazolo[1,5-a]pyrimidines
US5013737A (en) * 1988-02-22 1991-05-07 American Cyanamid Company 2,4,8-Trisubstituted-3H,6H-1,4,5A,8A-tetraazaacenaphtylene-3,5-(4H)-diones and 2,4-8-trisubstituted-4,5-dihydro-5-thioxo-3H,6H-1,4,5A,8A-tetrazaacenaphthylen-3-ones
US4916137A (en) * 1988-02-22 1990-04-10 American Cyanamid Company 5-(Substituted-amino)-8-(phenyl or substituted-phenyl)-3H,6H-1,4,5A,8A-tetraazaacenaphthylen-3-ones and treatment of neural behavior disorders
US20070179161A1 (en) * 2003-03-31 2007-08-02 Vernalis (Cambridge) Limited. Pyrazolopyrimidine compounds and their use in medicine
ES2222813B1 (es) * 2003-07-24 2005-12-16 Ferrer Internacional, S.A. N-(3-(3-sustituidas-pirazolo(1,5-a)pirimidin-7-il)-fenil)-sulfonamidas y composiciones y metodos relacionados.
WO2006033795A2 (en) * 2004-09-17 2006-03-30 Wyeth Substituted pyrazolo [1, 5-a] pyrimidines for inhibiting abnormal cell growth
WO2006033796A1 (en) * 2004-09-17 2006-03-30 Wyeth SUBSTITUTED PYRAZOLO [1,5-a] PYRIMIDINES AND PROCESS FOR MAKING SAME
EP1736475A1 (en) * 2005-06-21 2006-12-27 Ferrer Internacional, S.A. Halogenated pyrazolo[1,5-a]pyrimidines, processes, uses, compositions and intermediates

Also Published As

Publication number Publication date
BRPI0708813A2 (pt) 2011-05-24
WO2007109093A2 (en) 2007-09-27
EP1996594A2 (en) 2008-12-03
JP2009530296A (ja) 2009-08-27
WO2007109093A3 (en) 2008-01-24
US20070219186A1 (en) 2007-09-20
AU2007227557A1 (en) 2007-09-27
CA2643968A1 (en) 2007-09-27
CN101405289A (zh) 2009-04-08

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