AU2006323961A1 - Methods for generating antigen-specific effector T cells - Google Patents
Methods for generating antigen-specific effector T cells Download PDFInfo
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- AU2006323961A1 AU2006323961A1 AU2006323961A AU2006323961A AU2006323961A1 AU 2006323961 A1 AU2006323961 A1 AU 2006323961A1 AU 2006323961 A AU2006323961 A AU 2006323961A AU 2006323961 A AU2006323961 A AU 2006323961A AU 2006323961 A1 AU2006323961 A1 AU 2006323961A1
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| PCT/EP2006/069549 WO2007065957A2 (en) | 2005-12-09 | 2006-12-11 | Methods for generating antigen-specific effector t cells |
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| US7994298B2 (en) | 2004-09-24 | 2011-08-09 | Trustees Of Dartmouth College | Chimeric NK receptor and methods for treating cancer |
| JP2008521406A (ja) | 2004-11-24 | 2008-06-26 | フレッド ハッチンソン キャンサー リサーチ センター | 養子免疫療法のためのｉｌ−２１の使用法および腫瘍抗原の同定法 |
| ATE461215T1 (de) * | 2005-09-05 | 2010-04-15 | Immatics Biotechnologies Gmbh | Tumor-assoziierte peptide, welche an unterschiedliche menschliche leukozytenantigene der klasse ii binden |
| HRP20161191T1 (hr) | 2007-01-31 | 2016-11-18 | Yeda Research And Development Company Limited | Preusmjerene, genetski projektirane t regulacijske stanice i njihova uporaba u suspenziji autoimunih i upalnih bolesti |
| US8859229B2 (en) * | 2007-02-02 | 2014-10-14 | Yale University | Transient transfection with RNA |
| US10155038B2 (en) | 2007-02-02 | 2018-12-18 | Yale University | Cells prepared by transient transfection and methods of use thereof |
| US9249423B2 (en) | 2007-02-02 | 2016-02-02 | Yale University | Method of de-differentiating and re-differentiating somatic cells using RNA |
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| KR100900837B1 (ko) | 2007-12-07 | 2009-06-04 | (주)두비엘 | 리포펩타이드와 폴리(ｉ:ｃ)를 아쥬반트로 포함하는 강력한백신 조성물 |
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| DK2279253T3 (en) * | 2008-04-09 | 2017-02-13 | Maxcyte Inc | Construction and application of therapeutic compositions of freshly isolated cells |
| US20140161782A1 (en) * | 2008-06-09 | 2014-06-12 | Targazyme, Inc. | Augmentation of cell therapy efficacy including treatment with alpha 1-3 fucoslytransferase |
| EP2352756B1 (en) | 2008-11-24 | 2012-09-19 | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH | High affinity t cell receptor and use thereof |
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| GB0911566D0 (en) * | 2009-07-03 | 2009-08-12 | Immunocore Ltd | T cell receptors |
| US9273283B2 (en) | 2009-10-29 | 2016-03-01 | The Trustees Of Dartmouth College | Method of producing T cell receptor-deficient T cells expressing a chimeric receptor |
| WO2011059836A2 (en) | 2009-10-29 | 2011-05-19 | Trustees Of Dartmouth College | T cell receptor-deficient t cell compositions |
| US12492376B2 (en) | 2009-10-29 | 2025-12-09 | The Trustees Of Dartmouth College | T-cell receptor-deficient T cell compositions |
| BR112013006718B1 (pt) * | 2010-09-20 | 2021-12-07 | Tron - Translationale Onkologie An Der Universitätsmedizin Der Johannes Gutenberguniversität Mainz Gemeinnutzige Gmbh | Receptor de células t com especificidade para ny-eso-1, composição farmacêutica compreendendo o mesmo e uso do mesmo |
| CN110200997A (zh) * | 2011-03-23 | 2019-09-06 | 弗雷德哈钦森癌症研究中心 | 用于细胞免疫治疗的方法和组合物 |
| US9833476B2 (en) | 2011-08-31 | 2017-12-05 | The Trustees Of Dartmouth College | NKP30 receptor targeted therapeutics |
| AU2013243952A1 (en) | 2012-04-02 | 2014-10-30 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| US10501512B2 (en) | 2012-04-02 | 2019-12-10 | Modernatx, Inc. | Modified polynucleotides |
| US10501513B2 (en) | 2012-04-02 | 2019-12-10 | Modernatx, Inc. | Modified polynucleotides for the production of oncology-related proteins and peptides |
| JP6389166B2 (ja) | 2012-05-07 | 2018-09-12 | トラスティーズ・オブ・ダートマス・カレッジ | 抗ｂ７−ｈ６抗体、融合タンパク質、及びこれらを使用する方法 |
| WO2014043170A1 (en) * | 2012-09-11 | 2014-03-20 | Corning Incorporated | Consumable cryopreserved cells transiently overexpressing gene(s) encoding drug transporter proteins(s) and/or drug metabolizing enzyme(s) |
| CN102911267B (zh) * | 2012-09-19 | 2014-04-02 | 南方医科大学 | 一种结核/hiv抗原肽双特异性tcr、其重组逆转录病毒载体与应用 |
| CA2934729C (en) * | 2014-01-29 | 2021-08-17 | University Health Network | Methods and compositions for producing a cell expressing a t cell receptor |
| WO2016095934A2 (en) * | 2014-12-14 | 2016-06-23 | El Abd Hisham Mohamed Magdy | A novel genetic device to engineer cell behavior |
| WO2016127257A1 (en) | 2015-02-12 | 2016-08-18 | University Health Network | Chimeric antigen receptors |
| CN108778291B (zh) * | 2016-01-06 | 2020-11-10 | 健康研究公司 | 包含重组t细胞受体的组合物和文库以及使用重组t细胞受体的方法 |
| JP6952225B2 (ja) * | 2016-03-18 | 2021-10-20 | 北海道公立大学法人 札幌医科大学 | Ｔ細胞レセプターとその利用 |
| SG11201708680PA (en) * | 2016-03-31 | 2017-11-29 | Lion Tcr Pte Ltd | Non-activated t cells expressing exogenous virus-specific t cell receptor (tcr) |
| ES3008636T3 (en) | 2016-06-02 | 2025-03-24 | Immunocore Ltd | Dosing regimen for gp100-specific tcr - anti-cd3 scfv fusion protein |
| KR20200016224A (ko) | 2017-05-02 | 2020-02-14 | 이뮤노믹 쎄라퓨틱스, 인크. | 암 항원을 포함하는 lamp (리소솜 연관 막 단백질) 구축물 |
| CN107630005A (zh) * | 2017-09-19 | 2018-01-26 | 深圳市北科生物科技有限公司 | 表达plac1特异性tcr的t细胞及其应用 |
| EP3684821A4 (en) | 2017-09-19 | 2021-06-16 | The University Of British Columbia | ANTI-HLA-A2 ANTIBODIES AND METHOD OF USING THEREOF |
| CN107557339A (zh) * | 2017-09-19 | 2018-01-09 | 深圳市北科生物科技有限公司 | 特异性识别plac1的t细胞及其与细胞因子的联合的应用 |
| KR102740924B1 (ko) | 2017-09-20 | 2024-12-13 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 신규한 항-ｈｌａ-ａ2 항체 및 이의 용도 |
| WO2019196088A1 (en) * | 2018-04-13 | 2019-10-17 | Syz Cell Therapy Co. | Methods of obtaining tumor-specific t cell receptors |
| WO2019241549A1 (en) | 2018-06-15 | 2019-12-19 | A2 Biotherapeutics, Inc. | Foxp3-expressing car-t regulatory cells |
| CN110627895B (zh) * | 2018-06-25 | 2021-03-23 | 北京大学 | 肺癌特异性tcr及其分析技术和应用 |
| US12134637B2 (en) | 2018-07-12 | 2024-11-05 | Bgi Shenzhen | MART-1(27-35) epitope-specific T cell receptor |
| WO2021026522A2 (en) * | 2019-08-08 | 2021-02-11 | Cedars-Sinai Medical Center | Method of generating activated t cells for cancer therapy |
| US12378521B2 (en) | 2020-04-15 | 2025-08-05 | Amgen Inc. | Method for enhancing production of genetically engineered autologous T cells |
| US12241086B2 (en) | 2020-04-15 | 2025-03-04 | Amgen Inc. | Process for generating genetically engineered autologous T cells |
| CN112941030B (zh) * | 2021-01-25 | 2023-08-08 | 吉林大学 | 一种抗原特异性Treg及其制备方法和应用 |
| AU2022288058A1 (en) | 2021-06-07 | 2023-11-16 | Agonox, Inc. | Cxcr5, pd-1, and icos expressing tumor reactive cd4 t cells and their use |
| WO2024008274A1 (en) * | 2022-07-04 | 2024-01-11 | Universiteit Antwerpen | T regulatory cell modification |
| CN117797253A (zh) * | 2024-02-29 | 2024-04-02 | 诺未科技（北京）有限公司 | 一种能扩展t细胞抗原表位的肿瘤疫苗及其制备方法 |
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| US8211422B2 (en) * | 1992-03-18 | 2012-07-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Chimeric receptor genes and cells transformed therewith |
| EP1188825A1 (en) * | 2000-09-18 | 2002-03-20 | Universiteit Leiden | T cell receptor transfer into a candidate effector cell or a precursor thereof |
| US7723111B2 (en) * | 2001-03-09 | 2010-05-25 | The United States Of America As Represented By The Department Of Health And Human Services | Activated dual specificity lymphocytes and their methods of use |
| GB0111015D0 (en) * | 2001-05-04 | 2001-06-27 | Norsk Hydro As | Genetic material |
| JP2007512030A (ja) * | 2003-11-25 | 2007-05-17 | アルゴス・セラピューティクス・インコーポレーテッド | ｍＲＮＡをトランスフェクションした抗原提示細胞 |
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| WO2007065957A2 (en) | 2007-06-14 |
| KR20080077272A (ko) | 2008-08-21 |
| EP1960527A2 (en) | 2008-08-27 |
| WO2007065957A3 (en) | 2007-07-26 |
| CN101415827A (zh) | 2009-04-22 |
| JP2009518021A (ja) | 2009-05-07 |
| EP1795599A1 (en) | 2007-06-13 |
| CA2631785A1 (en) | 2007-06-14 |
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