AU2006305879B2 - PDX1-expressing dorsal and ventral foregut endoderm - Google Patents
PDX1-expressing dorsal and ventral foregut endoderm Download PDFInfo
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- AU2006305879B2 AU2006305879B2 AU2006305879A AU2006305879A AU2006305879B2 AU 2006305879 B2 AU2006305879 B2 AU 2006305879B2 AU 2006305879 A AU2006305879 A AU 2006305879A AU 2006305879 A AU2006305879 A AU 2006305879A AU 2006305879 B2 AU2006305879 B2 AU 2006305879B2
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- cells
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- foregut endoderm
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- C—CHEMISTRY; METALLURGY
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
- C12N5/0678—Stem cells; Progenitor cells; Precursor cells
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0679—Cells of the gastro-intestinal tract
- C12N5/068—Stem cells; Progenitors
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/117—Keratinocyte growth factors (KGF-1, i.e. FGF-7; KGF-2, i.e. FGF-12)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/119—Other fibroblast growth factors, e.g. FGF-4, FGF-8, FGF-10
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/405—Cell cycle regulated proteins, e.g. cyclins, cyclin-dependant kinases
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/41—Hedgehog proteins; Cyclopamine (inhibitor)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/415—Wnt; Frizzeled
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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- C12N2510/00—Genetically modified cells
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- Chemical & Material Sciences (AREA)
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- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Developmental Biology & Embryology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2012202481A AU2012202481B2 (en) | 2005-10-27 | 2012-04-30 | PDX1-expressing dorsal and ventral foregut endoderm |
| AU2015221494A AU2015221494B2 (en) | 2005-10-27 | 2015-09-03 | Pdx1- expressing dorsal and ventral foregut endoderm |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73091705P | 2005-10-27 | 2005-10-27 | |
| US60/730,917 | 2005-10-27 | ||
| PCT/US2006/042413 WO2007051038A2 (en) | 2005-10-27 | 2006-10-27 | Pdx1-expressing dorsal and ventral foregut endoderm |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2012202481A Division AU2012202481B2 (en) | 2005-10-27 | 2012-04-30 | PDX1-expressing dorsal and ventral foregut endoderm |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2006305879A1 AU2006305879A1 (en) | 2007-05-03 |
| AU2006305879B2 true AU2006305879B2 (en) | 2012-05-10 |
Family
ID=37769419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2006305879A Active AU2006305879B2 (en) | 2005-10-27 | 2006-10-27 | PDX1-expressing dorsal and ventral foregut endoderm |
Country Status (10)
| Country | Link |
|---|---|
| US (6) | US20070122905A1 (enExample) |
| EP (3) | EP3584311A1 (enExample) |
| JP (5) | JP5404047B2 (enExample) |
| CN (1) | CN101351547A (enExample) |
| AU (1) | AU2006305879B2 (enExample) |
| CA (2) | CA2627645C (enExample) |
| DK (2) | DK1957636T3 (enExample) |
| ES (2) | ES2687233T3 (enExample) |
| PL (1) | PL1957636T3 (enExample) |
| WO (1) | WO2007051038A2 (enExample) |
Families Citing this family (99)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003014313A2 (en) * | 2001-08-06 | 2003-02-20 | Bresagen, Ltd. | Alternative compositions and methods for the culture of stem cells |
| US8647873B2 (en) | 2004-04-27 | 2014-02-11 | Viacyte, Inc. | PDX1 expressing endoderm |
| US7541185B2 (en) * | 2003-12-23 | 2009-06-02 | Cythera, Inc. | Methods for identifying factors for differentiating definitive endoderm |
| US20050266554A1 (en) * | 2004-04-27 | 2005-12-01 | D Amour Kevin A | PDX1 expressing endoderm |
| WO2005063971A2 (en) | 2003-12-23 | 2005-07-14 | Cythera, Inc | Definitive endoderm |
| US20090010900A1 (en) * | 2004-07-07 | 2009-01-08 | The University Of North Carlolina At Chapel Hill | Embryonic Stem Cell Derivatives, and Methods of Making and Using the Same |
| WO2006020919A2 (en) * | 2004-08-13 | 2006-02-23 | University Of Georgia Research Foundation, Inc. | Compositions and methods for self-renewal and differentiation in human embryonic stem cells |
| US8017395B2 (en) | 2004-12-17 | 2011-09-13 | Lifescan, Inc. | Seeding cells on porous supports |
| ES2400916T3 (es) | 2005-06-08 | 2013-04-15 | Janssen Biotech, Inc. | Una terapia celular para degeneración ocular |
| DK1957636T3 (en) | 2005-10-27 | 2018-10-01 | Viacyte Inc | PDX1-EXPRESSING DORSAL AND VENTRAL FORTARM ENDODERM |
| AU2007220759A1 (en) | 2006-02-23 | 2007-09-07 | Viacyte, Inc. | Compositions and methods useful for culturing differentiable cells |
| DK2650360T3 (da) | 2006-03-02 | 2019-10-07 | Viacyte Inc | Endokrine prekursorceller, pancreatiske hormon udtrykkende celler og fremgangsmåder til fremstilling |
| US7695965B2 (en) | 2006-03-02 | 2010-04-13 | Cythera, Inc. | Methods of producing pancreatic hormones |
| US11254916B2 (en) | 2006-03-02 | 2022-02-22 | Viacyte, Inc. | Methods of making and using PDX1-positive pancreatic endoderm cells |
| US8741643B2 (en) | 2006-04-28 | 2014-06-03 | Lifescan, Inc. | Differentiation of pluripotent stem cells to definitive endoderm lineage |
| WO2008013664A2 (en) | 2006-07-26 | 2008-01-31 | Cythera, Inc. | Methods of producing pancreatic hormones |
| US9080145B2 (en) | 2007-07-01 | 2015-07-14 | Lifescan Corporation | Single pluripotent stem cell culture |
| EP2562248B1 (en) * | 2007-07-18 | 2021-06-09 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
| EP2610336A1 (en) | 2007-07-31 | 2013-07-03 | Lifescan, Inc. | Differentiation of human embryonic stem cells |
| US9005962B2 (en) * | 2007-08-24 | 2015-04-14 | The University Court Of The University Of Edinburgh | Regionalised endoderm cells and uses thereof |
| MX2010005805A (es) * | 2007-11-27 | 2010-06-09 | Lifescan Inc | Diferenciacion de celulas madre embrionarias humanas. |
| MX2010009251A (es) | 2008-02-21 | 2010-11-25 | Centocor Ortho Biotech Inc | Metodos, placas de superficie modificada y composiciones para la fijacion, el cultivo y el desprendimiento celular. |
| US8338170B2 (en) | 2008-04-21 | 2012-12-25 | Viacyte, Inc. | Methods for purifying endoderm and pancreatic endoderm cells derived from human embryonic stem cells |
| US8623648B2 (en) | 2008-04-24 | 2014-01-07 | Janssen Biotech, Inc. | Treatment of pluripotent cells |
| US20090298178A1 (en) * | 2008-06-03 | 2009-12-03 | D Amour Kevin Allen | Growth factors for production of definitive endoderm |
| ES2697798T3 (es) | 2008-06-30 | 2019-01-28 | Janssen Biotech Inc | Diferenciación de células madre pluripotentes |
| RU2522001C2 (ru) | 2008-10-31 | 2014-07-10 | Сентокор Орто Байотек Инк. | Дифференцирование человеческих эмбриональных стволовых клеток в линию панкреатических эндокринных клеток |
| KR102025158B1 (ko) | 2008-10-31 | 2019-09-25 | 얀센 바이오테크 인코포레이티드 | 인간 배아 줄기 세포의 췌장 내분비 계통으로의 분화 |
| US8008075B2 (en) | 2008-11-04 | 2011-08-30 | Viacyte, Inc. | Stem cell aggregate suspension compositions and methods of differentiation thereof |
| ES2743204T3 (es) | 2008-11-04 | 2020-02-18 | Viacyte Inc | Composiciones de suspensión de agregados de células madre y métodos para su diferenciación |
| US8895300B2 (en) | 2008-11-04 | 2014-11-25 | Viacyte, Inc. | Scalable primate pluripotent stem cell aggregate suspension culture and differentiation thereof |
| ES2667493T3 (es) * | 2008-11-14 | 2018-05-11 | Viacyte, Inc. | Encapsulación de células pancreáticas derivadas de células madre humanas pluripotentes |
| JP2012509085A (ja) | 2008-11-20 | 2012-04-19 | ヤンセン バイオテツク,インコーポレーテツド | マイクロキャリア上での多能性幹細胞の培養 |
| CA2744227C (en) | 2008-11-20 | 2018-10-02 | Centocor Ortho Biotech Inc. | Methods and compositions for cell attachment and cultivation on planar substrates |
| US9109245B2 (en) | 2009-04-22 | 2015-08-18 | Viacyte, Inc. | Cell compositions derived from dedifferentiated reprogrammed cells |
| US20100272695A1 (en) * | 2009-04-22 | 2010-10-28 | Alan Agulnick | Cell compositions derived from dedifferentiated reprogrammed cells |
| EP2435471A2 (en) * | 2009-05-29 | 2012-04-04 | Novo Nordisk A/S | INDUCED DERIVATION OF SPECIFIC ENDODERM FROM hPS CELL-DERIVED DEFINITIVE ENDODERM |
| KR101893021B1 (ko) * | 2009-07-20 | 2018-08-29 | 얀센 바이오테크 인코포레이티드 | 인간 배아 줄기 세포의 분화 |
| EP2456862A4 (en) | 2009-07-20 | 2013-02-27 | Janssen Biotech Inc | DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS |
| GB2485113B (en) * | 2009-07-20 | 2016-12-28 | Janssen Biotech Inc | Differentiation of human embryonic stem cells into cells of the pancreatic endoderm lineage |
| DK2516625T3 (da) | 2009-12-23 | 2024-09-09 | Janssen Biotech Inc | Differentiering af humane embryonale stamceller |
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| EP2823037A4 (en) | 2012-03-07 | 2015-09-16 | Janssen Biotech Inc | DEFINED MEDIA FOR THE EXPANSION AND CARE OF PLURIPOTENTAL STEM CELLS |
| JP6161603B2 (ja) | 2012-05-25 | 2017-07-12 | 学校法人 埼玉医科大学 | 膵臓ホルモン産生細胞の生産方法及び膵臓ホルモン産生細胞、並びに分化誘導促進剤 |
| CN108034633B (zh) | 2012-06-08 | 2022-08-02 | 詹森生物科技公司 | 人胚胎干细胞向胰腺内分泌细胞的分化 |
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| CN105705634A (zh) | 2012-12-31 | 2016-06-22 | 詹森生物科技公司 | 用于分化成胰腺内分泌细胞的人多能细胞的悬浮和群集 |
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