AU2006290435A1 - Modulation of immunostimulatory properties of short interfering ribonucleic acid (siRNA) by nucleotide modification - Google Patents

Modulation of immunostimulatory properties of short interfering ribonucleic acid (siRNA) by nucleotide modification Download PDF

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Publication number
AU2006290435A1
AU2006290435A1 AU2006290435A AU2006290435A AU2006290435A1 AU 2006290435 A1 AU2006290435 A1 AU 2006290435A1 AU 2006290435 A AU2006290435 A AU 2006290435A AU 2006290435 A AU2006290435 A AU 2006290435A AU 2006290435 A1 AU2006290435 A1 AU 2006290435A1
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Australia
Prior art keywords
modification
sense strand
sugar
modified nucleotide
sirna
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Abandoned
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AU2006290435A
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English (en)
Inventor
Ioanna Andreou
Marion Jurk
Stefan Pitsch
Christian Schetter
Eugen Uhlmann
Jorg Vollmer
Martin Weber
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Qiagen GmbH
Coley Pharmaceutical GmbH
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Qiagen GmbH
Coley Pharmaceutical GmbH
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Application filed by Qiagen GmbH, Coley Pharmaceutical GmbH filed Critical Qiagen GmbH
Publication of AU2006290435A1 publication Critical patent/AU2006290435A1/en
Abandoned legal-status Critical Current

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AU2006290435A 2005-09-16 2006-09-15 Modulation of immunostimulatory properties of short interfering ribonucleic acid (siRNA) by nucleotide modification Abandoned AU2006290435A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71759705P 2005-09-16 2005-09-16
US60/717,597 2005-09-16
PCT/IB2006/003356 WO2007031877A2 (en) 2005-09-16 2006-09-15 Modulation of immunostimulatory properties of short interfering ribonucleic acid (sirna) by nucleotide modification

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AU2006290435A1 true AU2006290435A1 (en) 2007-03-22

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AU2006290435A Abandoned AU2006290435A1 (en) 2005-09-16 2006-09-15 Modulation of immunostimulatory properties of short interfering ribonucleic acid (siRNA) by nucleotide modification

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US (1) US20090306177A1 (enExample)
EP (1) EP1924692A2 (enExample)
JP (1) JP2009508842A (enExample)
KR (1) KR20080047463A (enExample)
CN (1) CN101321868A (enExample)
AU (1) AU2006290435A1 (enExample)
BR (1) BRPI0616069A2 (enExample)
CA (1) CA2622761A1 (enExample)
EA (1) EA013375B1 (enExample)
IL (1) IL190154A0 (enExample)
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Cited By (1)

* Cited by examiner, † Cited by third party
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CN102770541A (zh) * 2010-01-07 2012-11-07 夸克医药公司 包含非核苷酸突出的寡核苷酸化合物

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US7935675B1 (en) 1994-07-15 2011-05-03 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US20030026782A1 (en) * 1995-02-07 2003-02-06 Arthur M. Krieg Immunomodulatory oligonucleotides
US6239116B1 (en) 1994-07-15 2001-05-29 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US6406705B1 (en) 1997-03-10 2002-06-18 University Of Iowa Research Foundation Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
ES2272069T3 (es) 1998-05-22 2007-04-16 Ottawa Health Research Institute Metodos y productos para inducir inmunidad en mucosas.
US7585847B2 (en) 2000-02-03 2009-09-08 Coley Pharmaceutical Group, Inc. Immunostimulatory nucleic acids for the treatment of asthma and allergy
ATE440618T1 (de) 2000-06-22 2009-09-15 Univ Iowa Res Found Kombination von cpg und antikírpern gegen cd19, cd20,cd22 oder cd40 zur prävention oder behandlung von krebs.
EP1499187B1 (en) 2002-04-04 2015-06-17 Zoetis Belgium S.A. Immunostimulatory g,u-containing oligoribonucleotides
US20040053880A1 (en) 2002-07-03 2004-03-18 Coley Pharmaceutical Group, Inc. Nucleic acid compositions for stimulating immune responses
US7569553B2 (en) 2002-07-03 2009-08-04 Coley Pharmaceutical Group, Inc. Nucleic acid compositions for stimulating immune responses
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