AU2006239937A1 - Chromane and chromene derivatives and uses thereof - Google Patents
Chromane and chromene derivatives and uses thereof Download PDFInfo
- Publication number
- AU2006239937A1 AU2006239937A1 AU2006239937A AU2006239937A AU2006239937A1 AU 2006239937 A1 AU2006239937 A1 AU 2006239937A1 AU 2006239937 A AU2006239937 A AU 2006239937A AU 2006239937 A AU2006239937 A AU 2006239937A AU 2006239937 A1 AU2006239937 A1 AU 2006239937A1
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- Prior art keywords
- disorder
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- methyl
- chromen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/20—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 hydrogenated in the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67382005P | 2005-04-22 | 2005-04-22 | |
US60/673,820 | 2005-04-22 | ||
PCT/US2006/015208 WO2006116165A1 (en) | 2005-04-22 | 2006-04-21 | Chromane and chromene derivatives and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2006239937A1 true AU2006239937A1 (en) | 2006-11-02 |
Family
ID=36888961
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2006239937A Abandoned AU2006239937A1 (en) | 2005-04-22 | 2006-04-21 | Chromane and chromene derivatives and uses thereof |
Country Status (19)
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0210397D0 (en) | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
US20050261347A1 (en) * | 2003-10-24 | 2005-11-24 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
US7435837B2 (en) * | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
GT200500297A (es) * | 2004-10-21 | 2006-10-27 | Sintesis asimetrica de dehidrobenzofuranos sustituidos | |
GT200500296A (es) * | 2004-10-21 | 2006-10-02 | Sintesis asimetrica de derivados del dehidrobenzofurano | |
CN101198322A (zh) * | 2005-04-22 | 2008-06-11 | 惠氏公司 | 用于治疗或预防抑郁症的新治疗组合 |
JP2008538577A (ja) * | 2005-04-22 | 2008-10-30 | ワイス | ジヒドロベンゾフラン誘導体およびその使用 |
TW200716584A (en) * | 2005-04-22 | 2007-05-01 | Wyeth Corp | Dihydrobenzofuran derivatives and uses thereof |
US20060258713A1 (en) * | 2005-04-22 | 2006-11-16 | Wyeth | Treatment of pain |
EP1871755A1 (en) * | 2005-04-22 | 2008-01-02 | Wyeth | Dihydrobenzofuran derivatives and uses thereof |
WO2006116221A2 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Therapeutic combinations for the treatment or prevention of psychotic disorders |
CA2605587A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Chromane and chromene derivatives and uses thereof |
MX2007013021A (es) * | 2005-04-22 | 2008-01-11 | Wyeth Corp | Derivados de benzofuranil-alcanamina y usos de los mismos como agonistas de 5-ht2c. |
JP2008538575A (ja) * | 2005-04-22 | 2008-10-30 | ワイス | ベンゾジオキサンおよびベンゾジオキソラン誘導体ならびにそれらの使用 |
TW200716106A (en) * | 2005-04-24 | 2007-05-01 | Wyeth Corp | Methods for modulating bladder function |
BRPI0709133A2 (pt) * | 2006-03-24 | 2011-06-28 | Wyeth Corp | métodos para tratar distúrbios cognitivos e outros |
TW200815388A (en) * | 2006-04-18 | 2008-04-01 | Wyeth Corp | Chromane and chromene derivatives and uses thereof |
EP2727585A1 (en) | 2006-05-16 | 2014-05-07 | Takeda Pharmaceutical Company Limited | In-vivo screening method |
CL2007003043A1 (es) * | 2006-10-24 | 2008-05-30 | Wyeth Corp | Compuestos derivados de cromano; composicion farmaceutica que los comprende; y uso para el tratamiento de un trastorno psicotico, bipolar, depresivo y ansiedad entre otros. |
CL2007003066A1 (es) * | 2006-10-25 | 2008-01-25 | Wyeth Corp | Metodo de obtencion de derivados de 8-fenil-cromanos por reduccion de la correspondiente amida. |
US8399410B2 (en) | 2007-08-06 | 2013-03-19 | Allergan, Inc. | Methods and devices for desmopressin drug delivery |
WO2009063992A1 (ja) | 2007-11-15 | 2009-05-22 | Takeda Pharmaceutical Company Limited | 縮合ピリジン誘導体およびその用途 |
US8914112B2 (en) | 2008-01-23 | 2014-12-16 | Boston Scienctific Neuromodulation Corporation | Methods and systems of treating pancreatitis pain caused by sphincter of Oddi dysfunction |
US8676322B2 (en) | 2008-01-30 | 2014-03-18 | Boston Scientific Neuromodulation Corporation | Methods and systems of treating pancreatitis pain |
EP2116618A1 (en) | 2008-05-09 | 2009-11-11 | Agency for Science, Technology And Research | Diagnosis and treatment of Kawasaki disease |
US20100286045A1 (en) | 2008-05-21 | 2010-11-11 | Bjarke Mirner Klein | Methods comprising desmopressin |
ES2677548T3 (es) | 2008-05-21 | 2018-08-03 | Ferring B.V. | Desmopresina bucodispersable para aumentar el periodo inicial de sueño ininterrumpido por nicturia |
EP2510949A4 (en) | 2009-12-11 | 2013-11-13 | Astellas Pharma Inc | THERAPEUTICS FOR FIBROMYALGIA |
CN101921252B (zh) * | 2010-07-02 | 2012-05-09 | 中国科学院上海有机化学研究所 | 1-氧杂苯并杂环类化合物、合成方法和用途 |
MX344516B (es) | 2010-12-21 | 2016-12-19 | Colgate Palmolive Co | Bifenoles halogenados como agentes antibacterianos. |
MY195032A (en) * | 2012-12-18 | 2023-01-04 | Dsm Ip Assets Bv | (6R,10R)-6,10,14-Trimetylpentadecan-2-One Prepared From (R)-6,10,14-Trimetylpentadec-5-en-2-One |
KR101592560B1 (ko) * | 2013-06-21 | 2016-02-05 | 제주대학교 산학협력단 | 신규 플라보노이드 및 그 용도 |
WO2015066344A1 (en) | 2013-11-01 | 2015-05-07 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists and compositions and methods of use |
KR102601972B1 (ko) | 2015-02-11 | 2023-11-13 | 선오비온 파마슈티컬스 인코포레이티드 | 중추 신경계 질환을 치료하기 위한 1-헤테로사이클릴 이소크로만일 화합물 및 유사체 |
CN116283877A (zh) | 2016-07-29 | 2023-06-23 | 赛诺维信制药公司 | 化合物、组合物及其用途 |
KR20190065246A (ko) | 2016-07-29 | 2019-06-11 | 선오비온 파마슈티컬스 인코포레이티드 | 화합물 및 조성물 및 이들의 용도 |
WO2019028165A1 (en) | 2017-08-02 | 2019-02-07 | Sunovion Pharmaceuticals Inc. | ISOCHROMAN COMPOUNDS AND USES THEREOF |
WO2019131902A1 (ja) | 2017-12-27 | 2019-07-04 | 武田薬品工業株式会社 | 腹圧性尿失禁および便失禁の治療薬 |
US20220117975A1 (en) * | 2019-02-17 | 2022-04-21 | Neurawell Therapeutics | Compositions and methods for treatment of depression and other disorders |
KR20210139376A (ko) | 2019-03-14 | 2021-11-22 | 선오비온 파마슈티컬스 인코포레이티드 | 이소크로마닐 화합물의 염, 및 이의 결정성 형태, 제조방법, 치료 용도 및 약제학적 조성물 |
Family Cites Families (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1262078A (en) | 1968-05-24 | 1972-02-02 | Fisons Pharmaceuticals Ltd | Preparation of phenoxy fumaric acid compounds and chromone-2-carboxylic acid compounds therefrom |
US4536518A (en) * | 1979-11-01 | 1985-08-20 | Pfizer Inc. | Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
US4654362A (en) * | 1983-12-05 | 1987-03-31 | Janssen Pharmaceutica, N.V. | Derivatives of 2,2'-iminobisethanol |
GB8814057D0 (en) * | 1988-06-14 | 1988-07-20 | Lundbeck & Co As H | New enantiomers & their isolation |
US5089637A (en) * | 1990-03-21 | 1992-02-18 | Pfizer Inc. | Process and intermediates for 2r-benzyl-chroman-6-carbaldehyde |
JP3283114B2 (ja) * | 1992-09-07 | 2002-05-20 | クミアイ化学工業株式会社 | 縮合ヘテロ環誘導体及び農園芸用殺菌剤 |
US5731324A (en) * | 1993-07-22 | 1998-03-24 | Eli Lilly And Company | Glycoprotein IIb/IIIa antagonists |
KR100330696B1 (ko) * | 1993-08-19 | 2002-10-04 | 얀센 파마슈티카 엔.브이. | 혈관수축성디하이드로벤조피란유도체 |
US6150402A (en) * | 1994-08-15 | 2000-11-21 | Loma Linda University Medical Center | Natriuretic compounds |
DE4430089A1 (de) | 1994-08-25 | 1996-02-29 | Bayer Ag | Verfahren zur enzymatischen Herstellung von enantiomerenreinen Chroman-2-carbonsäuren und deren Derivaten |
ES2169102T3 (es) * | 1994-10-14 | 2002-07-01 | Merck Patent Gmbh | (r)-(-)-2-(5-(4-fluorfenil)-3-piridilmetilaminometil)-cromano como agente activo sobre el sistema nervioso central. |
US5658796A (en) * | 1995-06-07 | 1997-08-19 | Seprachem, Inc. | Optical resolution of alkyl chroman-2-carboxylates |
DK0971878T3 (da) * | 1997-02-27 | 2008-06-30 | Takeda Pharmaceutical | Aminforbindelser, fremstillingen og anvendelsen deraf som inhibitorer af amyloid-beta-produktion |
FR2763335B1 (fr) * | 1997-05-16 | 2000-11-24 | Adir | Nouveaux composes heterocycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US6133277A (en) * | 1997-12-05 | 2000-10-17 | Janssen Pharmaceutica N.V. | (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties |
US20060258176A1 (en) * | 1998-02-05 | 2006-11-16 | Asm Japan K.K. | Method for forming insulation film |
US6011035A (en) * | 1998-06-30 | 2000-01-04 | Neuromed Technologies Inc. | Calcium channel blockers |
FR2791675B1 (fr) | 1999-03-30 | 2001-05-04 | Synthelabo | Derives de n-[2-(4-aminophenyl) ethyl] -2,3-dihydro-1,4- benzodioxinne-2-methanamine, leur preparation et leur application en therapeutique |
DE10044091A1 (de) * | 2000-09-07 | 2002-04-04 | Merck Patent Gmbh | Chromanonderivate |
UA75898C2 (en) * | 2000-11-14 | 2006-06-15 | Merck Patent Gmbh | Method for prophylaxis and treatment of eye diseases using antagonist of integrin receptors |
DE10120619A1 (de) * | 2001-04-26 | 2002-10-31 | Merck Patent Gmbh | 2-(5-(4-Fluorphenyl)-3-pyridylmethylaminomethyl-chroman |
HUP0401605A3 (en) * | 2001-08-01 | 2012-09-28 | Merck Patent Gmbh | Integrin inhibitors for the treatment of eye diseases |
EP1432696A1 (en) * | 2001-10-04 | 2004-06-30 | Wyeth | Chroman derivatives as 5-hydroxytryptamine-6 ligands |
WO2003029239A1 (en) | 2001-10-04 | 2003-04-10 | Wyeth | Chroman and benzofuran derivatives as 5-hydroxytryptamine-6 ligands |
WO2003031428A1 (en) * | 2001-10-05 | 2003-04-17 | Wyeth | Stereospecific process for the synthesis of 2-yl chroman derivatives |
WO2003031439A1 (en) * | 2001-10-05 | 2003-04-17 | Wyeth | Antidepressant chroman and chromene derivatives of 3-(1,2,3,6-tetrahydro-4-pyridinyl)-1h-indole |
WO2003031429A1 (en) * | 2001-10-05 | 2003-04-17 | Wyeth | A process for the stereoselective synthesis of 2-hydroxymethyl-chromans |
EP1445324A4 (en) * | 2001-11-09 | 2005-02-16 | Kaneka Corp | PROCESS FOR PRODUCING OPTICALLY ACTIVE CHROMAN DERIVATIVE AND INTERMEDIATE PRODUCT |
US7196108B2 (en) * | 2002-03-08 | 2007-03-27 | Incyte San Diego Inc. | Bicyclic heterocycles for the treatment of diabetes and other diseases |
AU2003291012A1 (en) | 2002-11-15 | 2004-06-15 | Galileo Pharmaceuticals, Inc. | Chroman derivatives for the reduction of inflammation symptoms |
WO2005033092A1 (en) | 2003-09-19 | 2005-04-14 | Galileo Pharmaceuticals, Inc. | Chroman derivatives |
DE10348257A1 (de) | 2003-10-16 | 2005-05-25 | Merck Patent Gmbh | Verfahren zur Herstellung von enantiomereneinen in 2-Position substituierten Chromanderivaten |
US20050261347A1 (en) * | 2003-10-24 | 2005-11-24 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
US7728155B2 (en) * | 2003-10-24 | 2010-06-01 | Wyeth Llc | Dihydrobenzofuranyl alkanamines and methods for using same as cns agents |
US7435837B2 (en) * | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
DE102004011265A1 (de) | 2004-03-09 | 2005-09-29 | Lutz F. Prof. Dr. Tietze | Synthese von Vitamin E |
GT200500297A (es) * | 2004-10-21 | 2006-10-27 | Sintesis asimetrica de dehidrobenzofuranos sustituidos | |
GT200500296A (es) * | 2004-10-21 | 2006-10-02 | Sintesis asimetrica de derivados del dehidrobenzofurano | |
EP1844038A2 (en) | 2004-11-24 | 2007-10-17 | Abbott Laboratories | Chromanylurea compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor and uses thereof |
CN101198322A (zh) * | 2005-04-22 | 2008-06-11 | 惠氏公司 | 用于治疗或预防抑郁症的新治疗组合 |
JP2008538575A (ja) * | 2005-04-22 | 2008-10-30 | ワイス | ベンゾジオキサンおよびベンゾジオキソラン誘導体ならびにそれらの使用 |
TW200716584A (en) * | 2005-04-22 | 2007-05-01 | Wyeth Corp | Dihydrobenzofuran derivatives and uses thereof |
JP2008538581A (ja) * | 2005-04-22 | 2008-10-30 | ワイス | {[(2r)−7−(2,6−ジクロロフェニル)−5−フルオロ−2,3−ジヒドロ−1−ベンゾフラン−2−イル]メチル}アミン塩酸塩の結晶形態 |
US20060258713A1 (en) * | 2005-04-22 | 2006-11-16 | Wyeth | Treatment of pain |
WO2006116221A2 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Therapeutic combinations for the treatment or prevention of psychotic disorders |
JP2008538577A (ja) * | 2005-04-22 | 2008-10-30 | ワイス | ジヒドロベンゾフラン誘導体およびその使用 |
MX2007013021A (es) * | 2005-04-22 | 2008-01-11 | Wyeth Corp | Derivados de benzofuranil-alcanamina y usos de los mismos como agonistas de 5-ht2c. |
CA2605587A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Chromane and chromene derivatives and uses thereof |
CA2605069A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Treatment of drug abuse |
TW200716106A (en) * | 2005-04-24 | 2007-05-01 | Wyeth Corp | Methods for modulating bladder function |
-
2006
- 2006-04-21 CA CA002605587A patent/CA2605587A1/en not_active Abandoned
- 2006-04-21 AR ARP060101590A patent/AR056320A1/es unknown
- 2006-04-21 WO PCT/US2006/015208 patent/WO2006116165A1/en active Application Filing
- 2006-04-21 CN CNA2006800222674A patent/CN101203505A/zh active Pending
- 2006-04-21 EP EP06758490A patent/EP1874756A1/en not_active Withdrawn
- 2006-04-21 TW TW095114313A patent/TW200716595A/zh unknown
- 2006-04-21 MX MX2007013163A patent/MX2007013163A/es unknown
- 2006-04-21 RU RU2007139541/04A patent/RU2007139541A/ru unknown
- 2006-04-21 PE PE2006000415A patent/PE20061297A1/es not_active Application Discontinuation
- 2006-04-21 US US11/409,467 patent/US7365095B2/en not_active Expired - Fee Related
- 2006-04-21 BR BRPI0610027-9A patent/BRPI0610027A2/pt not_active Application Discontinuation
- 2006-04-21 JP JP2008507952A patent/JP2008538576A/ja active Pending
- 2006-04-21 GT GT200600166A patent/GT200600166A/es unknown
- 2006-04-21 KR KR1020077027247A patent/KR20080008378A/ko not_active Application Discontinuation
- 2006-04-21 AU AU2006239937A patent/AU2006239937A1/en not_active Abandoned
-
2007
- 2007-10-19 ZA ZA200709052A patent/ZA200709052B/xx unknown
- 2007-10-22 CO CO07110959A patent/CO6321153A2/es not_active Application Discontinuation
- 2007-10-22 IL IL186837A patent/IL186837A0/en unknown
- 2007-11-06 NO NO20075641A patent/NO20075641L/no not_active Application Discontinuation
-
2008
- 2008-03-19 US US12/051,368 patent/US20080182891A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ZA200709052B (en) | 2009-08-26 |
MX2007013163A (es) | 2008-01-21 |
IL186837A0 (en) | 2008-02-09 |
US7365095B2 (en) | 2008-04-29 |
KR20080008378A (ko) | 2008-01-23 |
US20080182891A1 (en) | 2008-07-31 |
NO20075641L (no) | 2007-11-20 |
GT200600166A (es) | 2007-03-14 |
CO6321153A2 (es) | 2011-09-20 |
JP2008538576A (ja) | 2008-10-30 |
AR056320A1 (es) | 2007-10-03 |
EP1874756A1 (en) | 2008-01-09 |
US20060258714A1 (en) | 2006-11-16 |
RU2007139541A (ru) | 2009-05-27 |
TW200716595A (en) | 2007-05-01 |
CA2605587A1 (en) | 2006-11-02 |
PE20061297A1 (es) | 2006-12-24 |
WO2006116165A1 (en) | 2006-11-02 |
CN101203505A (zh) | 2008-06-18 |
BRPI0610027A2 (pt) | 2010-05-18 |
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