AU2006204724A1 - Cinnamide and hydrocinnamide derivatives with raf-kinase inhibitory activity - Google Patents

Cinnamide and hydrocinnamide derivatives with raf-kinase inhibitory activity Download PDF

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Publication number
AU2006204724A1
AU2006204724A1 AU2006204724A AU2006204724A AU2006204724A1 AU 2006204724 A1 AU2006204724 A1 AU 2006204724A1 AU 2006204724 A AU2006204724 A AU 2006204724A AU 2006204724 A AU2006204724 A AU 2006204724A AU 2006204724 A1 AU2006204724 A1 AU 2006204724A1
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Australia
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ring
optionally substituted
alkyl
aliphatic
independently
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AU2006204724A
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Inventor
Ruth S. Adams
Emily F. Calderwood
Alexandra E. Gould
Paul D. Greenspan
Matthew J. Lamarche
Yuan Tian
Tricia J. Vos
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Millennium Pharmaceuticals Inc
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Millennium Pharmaceuticals Inc
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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