AU2005299501B2 - Aromatic amides as inhibitors of c-fms kinase - Google Patents

Aromatic amides as inhibitors of c-fms kinase Download PDF

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Publication number
AU2005299501B2
AU2005299501B2 AU2005299501A AU2005299501A AU2005299501B2 AU 2005299501 B2 AU2005299501 B2 AU 2005299501B2 AU 2005299501 A AU2005299501 A AU 2005299501A AU 2005299501 A AU2005299501 A AU 2005299501A AU 2005299501 B2 AU2005299501 B2 AU 2005299501B2
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Prior art keywords
methyl
piperidin
carboxylic acid
cyano
phenyl
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AU2005299501A
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AU2005299501A1 (en
Inventor
Shelley K. Ballentine
Jinsheng Chen
Renee Desjarlais
Christopher M. Flores
Carl R. Illig
Carl L. Manthey
Sanath Meegalla
Christopher J. Molloy
Jonathan Rudolph
Mark J. Wall
Kenneth J. Wilson
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Janssen Pharmaceutica NV
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Janssen Pharmaceutica NV
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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AU2005299501A 2004-10-22 2005-10-20 Aromatic amides as inhibitors of c-fms kinase Ceased AU2005299501B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62119204P 2004-10-22 2004-10-22
US60/621,192 2004-10-22
PCT/US2005/038341 WO2006047504A1 (en) 2004-10-22 2005-10-20 Aromatic amides as inhibitors of c-fms kinase

Publications (2)

Publication Number Publication Date
AU2005299501A1 AU2005299501A1 (en) 2006-05-04
AU2005299501B2 true AU2005299501B2 (en) 2011-03-03

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AU2005299501A Ceased AU2005299501B2 (en) 2004-10-22 2005-10-20 Aromatic amides as inhibitors of c-fms kinase

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US (1) US7705042B2 (enExample)
EP (1) EP1807407B1 (enExample)
JP (1) JP5008569B2 (enExample)
CN (2) CN101084208A (enExample)
AT (1) ATE437864T1 (enExample)
AU (1) AU2005299501B2 (enExample)
DE (1) DE602005015742D1 (enExample)
WO (1) WO2006047504A1 (enExample)

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ES2430569T3 (es) 2005-02-18 2013-11-21 Astrazeneca Ab Compuestos antibacterianos derivados de piperidina
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US20060281788A1 (en) 2005-06-10 2006-12-14 Baumann Christian A Synergistic modulation of flt3 kinase using a flt3 inhibitor and a farnesyl transferase inhibitor
NL2000284C2 (nl) * 2005-11-04 2007-09-28 Pfizer Ltd Pyrazine-derivaten.
JP5182088B2 (ja) * 2006-04-19 2013-04-10 アステラス製薬株式会社 アゾールカルボキサミド誘導体
EP2016070B1 (en) 2006-04-20 2016-01-13 Janssen Pharmaceutica N.V. Inhibitors of c-fms kinase
KR101367645B1 (ko) 2006-04-20 2014-02-27 얀센 파마슈티카 엔.브이. Ｃ-ｆｍｓ 키나제의 저해제로서의 복소환식 화합물
JP2009534380A (ja) * 2006-04-20 2009-09-24 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ｃ−ｆｍｓキナーゼインヒビター
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SI2206707T1 (sl) 2007-10-24 2014-11-28 Astellas Pharma Inc. Azolkarboksamidna spojina ali njena sol
TWI498115B (zh) * 2007-12-27 2015-09-01 Daiichi Sankyo Co Ltd 咪唑羰基化合物
PL3354650T3 (pl) 2008-12-19 2022-06-13 Vertex Pharmaceuticals Incorporated Związki przydatne jako inhibitory kinazy atr
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JP2013526540A (ja) 2010-05-12 2013-06-24 バーテックス ファーマシューティカルズ インコーポレイテッド Ａｔｒキナーゼ阻害剤として有用な化合物
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JP5836367B2 (ja) 2010-05-12 2015-12-24 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ Ａｔｒキナーゼ阻害剤として有用な化合物
EP2627650A2 (en) * 2010-05-26 2013-08-21 Merck Sharp & Dohme Corp. N-phenyl imidazole carboxamide inhibitors of 3-phosphoinositide-dependent protein kinase-1
RU2018147217A (ru) 2011-09-30 2019-01-18 Вертекс Фармасьютикалз Инкорпорейтед Способы получения соединений, которые можно использовать в качестве ингибиторов киназы atr
AU2012315384B2 (en) 2011-09-30 2017-08-10 Vertex Pharmaceuticals Incorporated Treating pancreatic cancer and non-small cell lung cancer with ATR inhibitors
CN104582795B (zh) 2012-04-05 2018-04-20 沃泰克斯药物股份有限公司 可用作atr激酶抑制剂的化合物及其组合疗法
ES2607807T3 (es) * 2012-08-07 2017-04-04 Janssen Pharmaceutica Nv Procedimiento para la preparación de los inibidores de las quinasas c-fms
AU2013299922B2 (en) 2012-08-07 2018-06-21 Janssen Pharmaceutica Nv Process for the preparation of heterocyclic ester derivatives
DK2904406T3 (en) 2012-10-04 2018-06-18 Vertex Pharma METHOD OF DETERMINING THE ATR INHIBITION, INCREASED DNA DAMAGE
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WO2006047504A1 (en) 2006-05-04
JP5008569B2 (ja) 2012-08-22
EP1807407A1 (en) 2007-07-18
EP1807407B1 (en) 2009-07-29
US20060100201A1 (en) 2006-05-11
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