AU2005288689B2 - Methods and compositions relating to Alzheimer's disease - Google Patents
Methods and compositions relating to Alzheimer's disease Download PDFInfo
- Publication number
- AU2005288689B2 AU2005288689B2 AU2005288689A AU2005288689A AU2005288689B2 AU 2005288689 B2 AU2005288689 B2 AU 2005288689B2 AU 2005288689 A AU2005288689 A AU 2005288689A AU 2005288689 A AU2005288689 A AU 2005288689A AU 2005288689 B2 AU2005288689 B2 AU 2005288689B2
- Authority
- AU
- Australia
- Prior art keywords
- alzheimer
- protein
- disease
- proteins
- precursor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2011253636A AU2011253636B2 (en) | 2004-09-29 | 2011-11-23 | Methods and compositions relating to alzheimer's disease |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0421639.6 | 2004-09-29 | ||
| GBGB0421639.6A GB0421639D0 (en) | 2004-09-29 | 2004-09-29 | Methods and compositions relating to alzheimer's disease |
| PCT/GB2005/003756 WO2006035237A2 (en) | 2004-09-29 | 2005-09-29 | Methods and compositions relating to alzheimer's disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2011253636A Division AU2011253636B2 (en) | 2004-09-29 | 2011-11-23 | Methods and compositions relating to alzheimer's disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2005288689A1 AU2005288689A1 (en) | 2006-04-06 |
| AU2005288689B2 true AU2005288689B2 (en) | 2011-10-27 |
Family
ID=33397455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2005288689A Expired AU2005288689B2 (en) | 2004-09-29 | 2005-09-29 | Methods and compositions relating to Alzheimer's disease |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7897361B2 (cg-RX-API-DMAC7.html) |
| EP (3) | EP2562545A1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP5483816B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE495445T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2005288689B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2580532C (cg-RX-API-DMAC7.html) |
| DE (1) | DE602005025897D1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK2354795T3 (cg-RX-API-DMAC7.html) |
| GB (1) | GB0421639D0 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2006035237A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0421639D0 (en) * | 2004-09-29 | 2004-10-27 | Proteome Sciences Plc | Methods and compositions relating to alzheimer's disease |
| GB0426859D0 (en) * | 2004-12-07 | 2005-01-12 | Proteome Sciences Plc | Diagnosis of neurodegenerative disorders |
| GB2428240A (en) | 2005-07-14 | 2007-01-24 | Univ Gen Ve | Diagnostic method for brain damage-related disorders |
| ES2543341T3 (es) | 2005-09-13 | 2015-08-18 | National Research Council Of Canada | Métodos y composiciones para modular la actividad de células tumorales |
| GB0701626D0 (en) * | 2007-01-22 | 2007-03-07 | Cambridge Entpr Ltd | Methods and biomarkers for diagnosing and monitoring psychotic disorders |
| AT506819B1 (de) | 2008-06-12 | 2011-06-15 | Affiris Forschungs Und Entwicklungs Gmbh | Vakzin zur behandlung von alzheimer-krankheit |
| AU2009295357A1 (en) * | 2008-09-26 | 2010-04-01 | The University Of Melbourne | Alzheimer's disease biomarkers |
| IT1392551B1 (it) * | 2008-11-25 | 2012-03-09 | Bioindustry Park Del Canavese S P A | Biomarcatori per la diagnosi e per rilevare la progressione di malattie neurodegenerative, in particolare della sclerosi laterale amiotrofica |
| JP5755149B2 (ja) * | 2009-01-26 | 2015-07-29 | エレクトロフォレティクス リミテッドElectrophoretics Limited | 方法 |
| JP2010271078A (ja) | 2009-05-19 | 2010-12-02 | Mcbi:Kk | 認知機能障害疾患を含む精神疾患のバイオマーカーおよび該バイオマーカーを用いた認知機能障害疾患を含む精神疾患の検出方法 |
| CA2709621A1 (en) * | 2009-09-11 | 2011-03-11 | Electrophoretics Limited | Markers and methods relating to the assessment of alzheimer's disease |
| RU2627163C2 (ru) | 2009-11-24 | 2017-08-03 | Алетиа Байотерапьютикс Инк. | Антикластериновые антитела и антигенсвязывающие фрагменты и их использование для уменьшения объема новообразований |
| JP6012923B2 (ja) | 2010-12-22 | 2016-10-25 | 株式会社Mcbi | 認知機能障害疾患のバイオマーカーおよび該バイオマーカーを用いる認知機能障害疾患の検出方法 |
| JP5906519B2 (ja) * | 2011-09-13 | 2016-04-20 | 国立大学法人 熊本大学 | 二次元電気泳動による蛋白質の分離方法 |
| HK1201328A1 (en) * | 2011-11-18 | 2015-08-28 | Alnylam Pharmaceuticals, Inc. | Quantification of transthyretin and its isoforms |
| MX2014010164A (es) | 2012-02-22 | 2014-11-25 | Alethia Biotherapeutics Inc | Co-uso de un inhibidor de clusterina con un inhibidor de egfr para tratar cancer. |
| JP2015520123A (ja) | 2012-03-29 | 2015-07-16 | アリゾナ ボード オブ リージェンツ ア ボディ コーポレート オブ ザ ステイト オブ アリゾナ アクティング フォー アンド オン ビハーフ オブ アリゾナ ステイト ユニバーシティーArizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University | 個々のタンパク質バリアントに選択的な試薬を調製するナノスケールの方法 |
| USRE49625E1 (en) | 2012-03-29 | 2023-08-29 | Arizona Board Of Regents, A Body Corporate Of The State Of Arizona | Nanoscale process to generate reagents selective for individual protein variants |
| US10501513B2 (en) | 2012-04-02 | 2019-12-10 | Modernatx, Inc. | Modified polynucleotides for the production of oncology-related proteins and peptides |
| EP2834260A4 (en) | 2012-04-02 | 2016-08-10 | Moderna Therapeutics Inc | MODIFIED POLYNUCLEOTIDES FOR THE PREPARATION OF MEMBRANE PROTEINS |
| US10501512B2 (en) | 2012-04-02 | 2019-12-10 | Modernatx, Inc. | Modified polynucleotides |
| EP3255435A1 (en) | 2012-04-13 | 2017-12-13 | Oasis Diagnostics Corporation | Specific salivary biomarkers for risk detection, early diagnosis, prognosis and monitoring of alzheimer's and parkinson's diseases |
| WO2014040042A2 (en) | 2012-09-10 | 2014-03-13 | The Johns Hopkins University | Diagnostic assay for alzheimer's disease |
| US9891108B2 (en) | 2012-10-03 | 2018-02-13 | The Research Foundation For The State University Of New York | Spectroscopic method for Alzheimer's disease diagnosis |
| US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
| JP6416793B2 (ja) * | 2013-02-28 | 2018-10-31 | カプリオン プロテオミクス インコーポレーテッド | 結核のバイオマーカー及びその使用 |
| US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
| GB201310150D0 (en) | 2013-06-07 | 2013-07-24 | Electrophoretics Ltd | Methods and compositions relating to alzheimer's disease |
| GB201310203D0 (en) * | 2013-06-07 | 2013-07-24 | Electrophoretics Ltd | Materials and methods relating to Alzheimer's disease |
| EP3039431A4 (en) * | 2013-08-27 | 2017-05-03 | CRC for Mental Health Ltd. | Method of identifying biomarkers of neurological diseases and diagnosis of neurological diseases |
| GB201322094D0 (en) | 2013-12-13 | 2014-01-29 | Electrophoretics Ltd | Methods and compositions relating to alzheimers disease |
| EP3092494A4 (en) * | 2014-01-06 | 2017-10-18 | Children's Medical Center Corporation | Biomarkers for dementia and dementia related neurological disorders |
| GB201403489D0 (en) * | 2014-02-27 | 2014-04-16 | Univ London Queen Mary | Biomarkers for endometriosis |
| WO2016160594A1 (en) * | 2015-03-27 | 2016-10-06 | The Research Foundation For The State University Of New York | Methods and materials for reducing amyloid beta levels within a mammal |
| US9904961B2 (en) | 2015-05-07 | 2018-02-27 | Kuwait University | System and method for determining the feedback capacity of information distributed in a complex network |
| JP6193942B2 (ja) * | 2015-09-09 | 2017-09-06 | 株式会社Mcbi | 認知機能障害疾患のバイオマーカーおよび該バイオマーカーを用いる認知機能障害疾患の検出方法 |
| CN105403649B (zh) * | 2015-12-01 | 2018-03-20 | 深圳大学 | 一种检测ad的尿液多肽组ad生物标记物 |
| JP6947450B2 (ja) * | 2016-06-29 | 2021-10-13 | 学校法人自治医科大学 | バイオマーカー、診断用組成物、及び診断用キット |
| JP6947451B2 (ja) * | 2016-06-29 | 2021-10-13 | 学校法人自治医科大学 | バイオマーカー、診断用組成物、及び診断用キット |
| WO2019013341A1 (ja) * | 2017-07-14 | 2019-01-17 | 株式会社島津製作所 | 疾患検出方法 |
| CN111201030B (zh) | 2017-07-25 | 2024-11-01 | 真和制药有限公司 | 通过阻断tim-3和其配体的相互作用治疗癌症 |
| JP6408087B2 (ja) * | 2017-07-25 | 2018-10-17 | 株式会社Mcbi | 認知機能障害疾患のバイオマーカーおよび該バイオマーカーを用いる認知機能障害疾患の検出方法 |
| CA3127113A1 (en) | 2019-01-30 | 2020-08-06 | Dongxu Sun | Anti-gal3 antibodies and uses thereof |
| CN113024651A (zh) * | 2019-12-25 | 2021-06-25 | 中国医学科学院药物研究所 | 阿尔茨海默病生物标志物及其应用 |
| JP2023528797A (ja) | 2020-05-26 | 2023-07-06 | トゥルーバインディング,インコーポレイテッド | ガレクチン-3を遮断することにより炎症性疾患を処置する方法 |
| US20220260559A1 (en) * | 2020-11-04 | 2022-08-18 | Seer, Inc. | Biomarkers for diagnosing alzheimer's disease |
| CN115808492A (zh) * | 2021-09-14 | 2023-03-17 | 中国科学院深圳先进技术研究院 | 一种阿尔兹海默症生物标志物天冬酰胺及其应用 |
| CA3268498A1 (en) * | 2022-10-18 | 2024-04-25 | Immungenetics Ag | IDENTIFICATION OF A SUBJECT SUFFERING FROM ALZHEIMER'S DISEASE OR PRESENTING A RISK OF DEVELOPING ALZHEIMER'S DISEASE |
| CN117831756B (zh) * | 2024-03-05 | 2024-06-28 | 精智未来(广州)智能科技有限公司 | 一种认知障碍的辅助分析方法、装置、设备及存储介质 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020174447A1 (en) * | 2001-01-23 | 2002-11-21 | Greenspan Ralph J. | Method for functional mapping of an alzheimer's disease gene network and for identifying therapeutic agents for the treatment of alzheimer's disease |
| WO2004030522A2 (en) * | 2002-10-02 | 2004-04-15 | Dmi Biosciences, Inc. | Diagnosis and monitoring of diseases |
| WO2004074837A1 (en) * | 2003-02-24 | 2004-09-02 | Digitalbiotech Co., Ltd. | Method for measuring the level of anti-beta-amyloid antibody in body fluids and diagnostic kit for alzheimer’s disease using same |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US4987071A (en) | 1986-12-03 | 1991-01-22 | University Patents, Inc. | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
| US6342350B1 (en) * | 1997-09-05 | 2002-01-29 | The General Hospital Corporation | Alpha-2-macroglobulin diagnostic test |
| US20030211622A1 (en) * | 1998-06-29 | 2003-11-13 | Roberts L. Jackson | Methods and compositions to assess oxidative brain injury |
| US20030131364A1 (en) | 1999-04-27 | 2003-07-10 | Karen Duff | Method for producing transgenic animal models with modulated phenotype and animals produced therefrom |
| JP2001249128A (ja) * | 2000-03-06 | 2001-09-14 | Ikagaku:Kk | 動脈硬化症またはアルツハイマー病の診断用キット |
| US6528309B2 (en) * | 2001-03-19 | 2003-03-04 | The Regents Of The University Of California | Vacuum-mediated desiccation protection of cells |
| US6451547B1 (en) * | 2001-04-25 | 2002-09-17 | Syn X Pharma | Process for differential diagnosis of Alzheimer's dementia and device therefor |
| DE10158180A1 (de) * | 2001-11-28 | 2003-09-11 | Biovision Ag | Verfahren zum Nachweis von Morbus Alzheimer und zur Unterscheidung von Morbus Alzheimer gegenüber anderen demenziellen Erkrankungen, zugehörige Peptide und deren Verwendung |
| AU2003253014A1 (en) * | 2002-06-21 | 2004-01-06 | Innogenetics N.V. | Method for the diagnosis and differential diagnosis of neurological diseases |
| EP1572932A4 (en) * | 2002-07-03 | 2008-05-14 | Univ Illinois | REAGENTS AND METHODS FOR IDENTIFYING AND MODULATING THE EXPRESSION OF TUMOR GENE SCENARIAS |
| GB0421639D0 (en) * | 2004-09-29 | 2004-10-27 | Proteome Sciences Plc | Methods and compositions relating to alzheimer's disease |
-
2004
- 2004-09-29 GB GBGB0421639.6A patent/GB0421639D0/en not_active Ceased
-
2005
- 2005-09-29 US US11/664,076 patent/US7897361B2/en not_active Expired - Lifetime
- 2005-09-29 WO PCT/GB2005/003756 patent/WO2006035237A2/en not_active Ceased
- 2005-09-29 AU AU2005288689A patent/AU2005288689B2/en not_active Expired
- 2005-09-29 EP EP12191625A patent/EP2562545A1/en not_active Withdrawn
- 2005-09-29 EP EP05788728A patent/EP1794594B1/en not_active Expired - Lifetime
- 2005-09-29 EP EP10010288.8A patent/EP2354795B1/en not_active Expired - Lifetime
- 2005-09-29 AT AT05788728T patent/ATE495445T1/de not_active IP Right Cessation
- 2005-09-29 DK DK10010288.8T patent/DK2354795T3/en active
- 2005-09-29 DE DE602005025897T patent/DE602005025897D1/de not_active Expired - Lifetime
- 2005-09-29 CA CA2580532A patent/CA2580532C/en not_active Expired - Lifetime
- 2005-09-29 JP JP2007534083A patent/JP5483816B2/ja not_active Expired - Lifetime
-
2011
- 2011-01-12 US US13/005,121 patent/US20110165146A1/en not_active Abandoned
- 2011-06-08 JP JP2011128088A patent/JP5893269B2/ja not_active Expired - Lifetime
-
2014
- 2014-08-05 JP JP2014159434A patent/JP2014209132A/ja active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020174447A1 (en) * | 2001-01-23 | 2002-11-21 | Greenspan Ralph J. | Method for functional mapping of an alzheimer's disease gene network and for identifying therapeutic agents for the treatment of alzheimer's disease |
| WO2004030522A2 (en) * | 2002-10-02 | 2004-04-15 | Dmi Biosciences, Inc. | Diagnosis and monitoring of diseases |
| WO2004074837A1 (en) * | 2003-02-24 | 2004-09-02 | Digitalbiotech Co., Ltd. | Method for measuring the level of anti-beta-amyloid antibody in body fluids and diagnostic kit for alzheimer’s disease using same |
Non-Patent Citations (3)
| Title |
|---|
| Andreasen, N. et al., Arch Neurol. 1999, Vol.56, pages 673-680 * |
| Kanai, M. et al., Annals of Neurology, 1998, Vol.44, No.1, pages 17-26 * |
| Tilleman, K. et al., Proteomics, 2002, Vol.2, pages 94-104 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP5483816B2 (ja) | 2014-05-07 |
| CA2580532A1 (en) | 2006-04-06 |
| AU2005288689A1 (en) | 2006-04-06 |
| JP2008514946A (ja) | 2008-05-08 |
| EP1794594A2 (en) | 2007-06-13 |
| US7897361B2 (en) | 2011-03-01 |
| JP2014209132A (ja) | 2014-11-06 |
| GB0421639D0 (en) | 2004-10-27 |
| ATE495445T1 (de) | 2011-01-15 |
| DE602005025897D1 (de) | 2011-02-24 |
| EP2562545A1 (en) | 2013-02-27 |
| EP2354795B1 (en) | 2014-12-17 |
| DK2354795T3 (en) | 2015-02-16 |
| EP2354795A1 (en) | 2011-08-10 |
| US20080070995A1 (en) | 2008-03-20 |
| WO2006035237A2 (en) | 2006-04-06 |
| WO2006035237A3 (en) | 2006-08-03 |
| JP5893269B2 (ja) | 2016-03-23 |
| JP2011209291A (ja) | 2011-10-20 |
| CA2580532C (en) | 2019-06-25 |
| US20110165146A1 (en) | 2011-07-07 |
| EP1794594B1 (en) | 2011-01-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |