AU2005288689B2 - Methods and compositions relating to Alzheimer's disease - Google Patents

Methods and compositions relating to Alzheimer's disease Download PDF

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Publication number
AU2005288689B2
AU2005288689B2 AU2005288689A AU2005288689A AU2005288689B2 AU 2005288689 B2 AU2005288689 B2 AU 2005288689B2 AU 2005288689 A AU2005288689 A AU 2005288689A AU 2005288689 A AU2005288689 A AU 2005288689A AU 2005288689 B2 AU2005288689 B2 AU 2005288689B2
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AU
Australia
Prior art keywords
alzheimer
protein
disease
proteins
precursor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU2005288689A
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English (en)
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AU2005288689A1 (en
Inventor
Christian Baumann
Helen Byers
Abdul Hye
Richard Joubert
Stefan Kienle
Karsten Kuhn
Simon Lovestone
Stephen Lynham
Petra Prefot
Thorsten Prinz
Juergen Schaefer
Malcolm Ward
Jules Westbrook
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kings College London
Proteome Sciences PLC
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Kings College London
Proteome Sciences PLC
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Publication date
Application filed by Kings College London, Proteome Sciences PLC filed Critical Kings College London
Publication of AU2005288689A1 publication Critical patent/AU2005288689A1/en
Application granted granted Critical
Publication of AU2005288689B2 publication Critical patent/AU2005288689B2/en
Priority to AU2011253636A priority Critical patent/AU2011253636B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
    • G01N2800/2821Alzheimer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
AU2005288689A 2004-09-29 2005-09-29 Methods and compositions relating to Alzheimer's disease Expired AU2005288689B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2011253636A AU2011253636B2 (en) 2004-09-29 2011-11-23 Methods and compositions relating to alzheimer's disease

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0421639.6 2004-09-29
GBGB0421639.6A GB0421639D0 (en) 2004-09-29 2004-09-29 Methods and compositions relating to alzheimer's disease
PCT/GB2005/003756 WO2006035237A2 (en) 2004-09-29 2005-09-29 Methods and compositions relating to alzheimer's disease

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2011253636A Division AU2011253636B2 (en) 2004-09-29 2011-11-23 Methods and compositions relating to alzheimer's disease

Publications (2)

Publication Number Publication Date
AU2005288689A1 AU2005288689A1 (en) 2006-04-06
AU2005288689B2 true AU2005288689B2 (en) 2011-10-27

Family

ID=33397455

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005288689A Expired AU2005288689B2 (en) 2004-09-29 2005-09-29 Methods and compositions relating to Alzheimer's disease

Country Status (10)

Country Link
US (2) US7897361B2 (cg-RX-API-DMAC7.html)
EP (3) EP2562545A1 (cg-RX-API-DMAC7.html)
JP (3) JP5483816B2 (cg-RX-API-DMAC7.html)
AT (1) ATE495445T1 (cg-RX-API-DMAC7.html)
AU (1) AU2005288689B2 (cg-RX-API-DMAC7.html)
CA (1) CA2580532C (cg-RX-API-DMAC7.html)
DE (1) DE602005025897D1 (cg-RX-API-DMAC7.html)
DK (1) DK2354795T3 (cg-RX-API-DMAC7.html)
GB (1) GB0421639D0 (cg-RX-API-DMAC7.html)
WO (1) WO2006035237A2 (cg-RX-API-DMAC7.html)

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GB0426859D0 (en) * 2004-12-07 2005-01-12 Proteome Sciences Plc Diagnosis of neurodegenerative disorders
GB2428240A (en) 2005-07-14 2007-01-24 Univ Gen Ve Diagnostic method for brain damage-related disorders
ES2543341T3 (es) 2005-09-13 2015-08-18 National Research Council Of Canada Métodos y composiciones para modular la actividad de células tumorales
GB0701626D0 (en) * 2007-01-22 2007-03-07 Cambridge Entpr Ltd Methods and biomarkers for diagnosing and monitoring psychotic disorders
AT506819B1 (de) 2008-06-12 2011-06-15 Affiris Forschungs Und Entwicklungs Gmbh Vakzin zur behandlung von alzheimer-krankheit
AU2009295357A1 (en) * 2008-09-26 2010-04-01 The University Of Melbourne Alzheimer's disease biomarkers
IT1392551B1 (it) * 2008-11-25 2012-03-09 Bioindustry Park Del Canavese S P A Biomarcatori per la diagnosi e per rilevare la progressione di malattie neurodegenerative, in particolare della sclerosi laterale amiotrofica
JP5755149B2 (ja) * 2009-01-26 2015-07-29 エレクトロフォレティクス リミテッドElectrophoretics Limited 方法
JP2010271078A (ja) 2009-05-19 2010-12-02 Mcbi:Kk 認知機能障害疾患を含む精神疾患のバイオマーカーおよび該バイオマーカーを用いた認知機能障害疾患を含む精神疾患の検出方法
CA2709621A1 (en) * 2009-09-11 2011-03-11 Electrophoretics Limited Markers and methods relating to the assessment of alzheimer's disease
RU2627163C2 (ru) 2009-11-24 2017-08-03 Алетиа Байотерапьютикс Инк. Антикластериновые антитела и антигенсвязывающие фрагменты и их использование для уменьшения объема новообразований
JP6012923B2 (ja) 2010-12-22 2016-10-25 株式会社Mcbi 認知機能障害疾患のバイオマーカーおよび該バイオマーカーを用いる認知機能障害疾患の検出方法
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USRE49625E1 (en) 2012-03-29 2023-08-29 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Nanoscale process to generate reagents selective for individual protein variants
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US9891108B2 (en) 2012-10-03 2018-02-13 The Research Foundation For The State University Of New York Spectroscopic method for Alzheimer's disease diagnosis
US9265458B2 (en) 2012-12-04 2016-02-23 Sync-Think, Inc. Application of smooth pursuit cognitive testing paradigms to clinical drug development
JP6416793B2 (ja) * 2013-02-28 2018-10-31 カプリオン プロテオミクス インコーポレーテッド 結核のバイオマーカー及びその使用
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GB201310203D0 (en) * 2013-06-07 2013-07-24 Electrophoretics Ltd Materials and methods relating to Alzheimer's disease
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WO2016160594A1 (en) * 2015-03-27 2016-10-06 The Research Foundation For The State University Of New York Methods and materials for reducing amyloid beta levels within a mammal
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JP6947450B2 (ja) * 2016-06-29 2021-10-13 学校法人自治医科大学 バイオマーカー、診断用組成物、及び診断用キット
JP6947451B2 (ja) * 2016-06-29 2021-10-13 学校法人自治医科大学 バイオマーカー、診断用組成物、及び診断用キット
WO2019013341A1 (ja) * 2017-07-14 2019-01-17 株式会社島津製作所 疾患検出方法
CN111201030B (zh) 2017-07-25 2024-11-01 真和制药有限公司 通过阻断tim-3和其配体的相互作用治疗癌症
JP6408087B2 (ja) * 2017-07-25 2018-10-17 株式会社Mcbi 認知機能障害疾患のバイオマーカーおよび該バイオマーカーを用いる認知機能障害疾患の検出方法
CA3127113A1 (en) 2019-01-30 2020-08-06 Dongxu Sun Anti-gal3 antibodies and uses thereof
CN113024651A (zh) * 2019-12-25 2021-06-25 中国医学科学院药物研究所 阿尔茨海默病生物标志物及其应用
JP2023528797A (ja) 2020-05-26 2023-07-06 トゥルーバインディング,インコーポレイテッド ガレクチン-3を遮断することにより炎症性疾患を処置する方法
US20220260559A1 (en) * 2020-11-04 2022-08-18 Seer, Inc. Biomarkers for diagnosing alzheimer's disease
CN115808492A (zh) * 2021-09-14 2023-03-17 中国科学院深圳先进技术研究院 一种阿尔兹海默症生物标志物天冬酰胺及其应用
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Also Published As

Publication number Publication date
JP5483816B2 (ja) 2014-05-07
CA2580532A1 (en) 2006-04-06
AU2005288689A1 (en) 2006-04-06
JP2008514946A (ja) 2008-05-08
EP1794594A2 (en) 2007-06-13
US7897361B2 (en) 2011-03-01
JP2014209132A (ja) 2014-11-06
GB0421639D0 (en) 2004-10-27
ATE495445T1 (de) 2011-01-15
DE602005025897D1 (de) 2011-02-24
EP2562545A1 (en) 2013-02-27
EP2354795B1 (en) 2014-12-17
DK2354795T3 (en) 2015-02-16
EP2354795A1 (en) 2011-08-10
US20080070995A1 (en) 2008-03-20
WO2006035237A2 (en) 2006-04-06
WO2006035237A3 (en) 2006-08-03
JP5893269B2 (ja) 2016-03-23
JP2011209291A (ja) 2011-10-20
CA2580532C (en) 2019-06-25
US20110165146A1 (en) 2011-07-07
EP1794594B1 (en) 2011-01-12

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