AU2005216904B2 - Modulation of inflammatory and metastatic processes - Google Patents

Modulation of inflammatory and metastatic processes Download PDF

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Publication number
AU2005216904B2
AU2005216904B2 AU2005216904A AU2005216904A AU2005216904B2 AU 2005216904 B2 AU2005216904 B2 AU 2005216904B2 AU 2005216904 A AU2005216904 A AU 2005216904A AU 2005216904 A AU2005216904 A AU 2005216904A AU 2005216904 B2 AU2005216904 B2 AU 2005216904B2
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AU
Australia
Prior art keywords
groups
substituted
benzimidazol
unsubstituted
amino
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005216904A
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English (en)
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AU2005216904A1 (en
Inventor
Carla C. Heise
Sang H. Lee
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Novartis Vaccines and Diagnostics Inc
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Novartis Vaccines and Diagnostics Inc
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Application filed by Novartis Vaccines and Diagnostics Inc filed Critical Novartis Vaccines and Diagnostics Inc
Publication of AU2005216904A1 publication Critical patent/AU2005216904A1/en
Assigned to NOVARTIS VACCINES AND DIAGNOSTICS, INC. reassignment NOVARTIS VACCINES AND DIAGNOSTICS, INC. Request for Assignment Assignors: CHIRON CORPORATION
Assigned to NOVARTIS VACCINES AND DIAGNOSTICS, INC. reassignment NOVARTIS VACCINES AND DIAGNOSTICS, INC. Alteration of Name(s) of Applicant(s) under S113 Assignors: CHIRON CORPORATION
Application granted granted Critical
Publication of AU2005216904B2 publication Critical patent/AU2005216904B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2005216904A 2004-02-20 2005-02-18 Modulation of inflammatory and metastatic processes Ceased AU2005216904B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US54639504P 2004-02-20 2004-02-20
US60/546,395 2004-02-20
US54710304P 2004-02-23 2004-02-23
US60/547,103 2004-02-23
US55477104P 2004-03-19 2004-03-19
US60/554,771 2004-03-19
PCT/US2005/005316 WO2005082340A2 (en) 2004-02-20 2005-02-18 Modulation of inflammatory and metastatic processes

Publications (2)

Publication Number Publication Date
AU2005216904A1 AU2005216904A1 (en) 2005-09-09
AU2005216904B2 true AU2005216904B2 (en) 2010-11-25

Family

ID=34916329

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005216904A Ceased AU2005216904B2 (en) 2004-02-20 2005-02-18 Modulation of inflammatory and metastatic processes

Country Status (10)

Country Link
US (1) US7875624B2 (enExample)
EP (1) EP1718306A2 (enExample)
JP (1) JP5019884B2 (enExample)
CN (1) CN1960731B (enExample)
AU (1) AU2005216904B2 (enExample)
BR (1) BRPI0507891A (enExample)
CA (1) CA2556872C (enExample)
IL (1) IL177574A0 (enExample)
RU (1) RU2377988C2 (enExample)
WO (1) WO2005082340A2 (enExample)

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US8404718B2 (en) 2005-01-21 2013-03-26 Astex Therapeutics Limited Combinations of pyrazole kinase inhibitors
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WO2006077428A1 (en) * 2005-01-21 2006-07-27 Astex Therapeutics Limited Pharmaceutical compounds
KR101387985B1 (ko) * 2005-01-27 2014-04-25 노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 전이 종양의 치료
PT1885187E (pt) * 2005-05-13 2013-12-16 Novartis Ag Métodos para o tratamento de cancro resistente a fármacos
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RU2425041C2 (ru) * 2005-05-23 2011-07-27 Новартис Аг Кристаллические и другие формы солей, образованных из молочной кислоты и 4-амино-5-фтор-3-[6-(4-метилпиперазин-1-ил)-1н-бензимидазол-2-ил]-1н-хинолин-2-она
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CA2556872C (en) 2015-05-12
RU2006133536A (ru) 2008-03-27
US20050239825A1 (en) 2005-10-27
EP1718306A2 (en) 2006-11-08
US7875624B2 (en) 2011-01-25
WO2005082340A2 (en) 2005-09-09
WO2005082340A3 (en) 2006-05-04
RU2377988C2 (ru) 2010-01-10
JP2007523185A (ja) 2007-08-16
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