AU2003295396B2 - Heteroaryl-pyramidine derivatives as JAK inhibitors - Google Patents
Heteroaryl-pyramidine derivatives as JAK inhibitors Download PDFInfo
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- AU2003295396B2 AU2003295396B2 AU2003295396A AU2003295396A AU2003295396B2 AU 2003295396 B2 AU2003295396 B2 AU 2003295396B2 AU 2003295396 A AU2003295396 A AU 2003295396A AU 2003295396 A AU2003295396 A AU 2003295396A AU 2003295396 B2 AU2003295396 B2 AU 2003295396B2
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- iva
- ivb
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- hydrogen
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Landscapes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42357902P | 2002-11-04 | 2002-11-04 | |
| US60/423,579 | 2002-11-04 | ||
| PCT/US2003/035163 WO2004041814A1 (en) | 2002-11-04 | 2003-11-04 | Heteroaryl-pyramidine derivatives as jak inhibitors |
Publications (2)
| Publication Number | Publication Date |
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| AU2003295396A1 AU2003295396A1 (en) | 2004-06-07 |
| AU2003295396B2 true AU2003295396B2 (en) | 2009-02-26 |
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| Application Number | Title | Priority Date | Filing Date |
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| AU2003295396A Ceased AU2003295396B2 (en) | 2002-11-04 | 2003-11-04 | Heteroaryl-pyramidine derivatives as JAK inhibitors |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7259161B2 (https=) |
| EP (1) | EP1562938B1 (https=) |
| JP (2) | JP4688498B2 (https=) |
| AT (1) | ATE371656T1 (https=) |
| AU (1) | AU2003295396B2 (https=) |
| CA (1) | CA2506773A1 (https=) |
| DE (1) | DE60316013T2 (https=) |
| ES (1) | ES2289349T3 (https=) |
| WO (1) | WO2004041814A1 (https=) |
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| WO2002022605A1 (en) * | 2000-09-15 | 2002-03-21 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| TWI329105B (en) | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
| HRP20050089B1 (hr) | 2002-07-29 | 2015-06-19 | Rigel Pharmaceuticals | Upotreba 2,4 pirimidindiaminskog spoja za proizvodnju lijeka za lijeäśenje ili sprjeäśavanje autoimunosne bolesti |
| WO2005012294A1 (en) | 2003-07-30 | 2005-02-10 | Rigel Pharmaceuticals, Inc. | 2,4-pyrimidinediamine compounds for use in the treatment or prevention of autoimmune diseases |
| US20090054417A1 (en) * | 2004-07-28 | 2009-02-26 | Irm Llc | Compounds and compositions as modulators of steroid hormone nuclear receptors |
| EP1807418A2 (en) | 2004-10-22 | 2007-07-18 | Amgen, Inc | Substituted nitrogen-containing heterocycles as vanilloid receptor ligands and their uses as medicament |
| SI1814878T1 (sl) | 2004-11-24 | 2012-06-29 | Rigel Pharmaceuticals Inc | Spojine spiro-2,4-pirimidindiamina in njihova uporaba |
| KR20070114130A (ko) | 2005-02-14 | 2007-11-29 | 존슨 앤드 존슨 비젼 케어, 인코포레이티드 | 착용감이 편안한 안용 장치 및 이의 제조방법 |
| EP1883302A4 (en) * | 2005-05-03 | 2009-05-20 | Rigel Pharmaceuticals Inc | JAK KINASE HEMMER AND ITS USE |
| BRPI0610876B8 (pt) | 2005-06-08 | 2021-05-25 | Rigel Pharmaceuticals Inc | composto, formulação farmacêutica, e métodos de inibir uma atividade de uma jak cinase, e de inibir uma cascata de transdução de sinal em que jak3 cinase desempenha um papel |
| US20070203161A1 (en) | 2006-02-24 | 2007-08-30 | Rigel Pharmaceuticals, Inc. | Compositions and methods for inhibition of the jak pathway |
| JP5191391B2 (ja) | 2005-11-01 | 2013-05-08 | ターゲジェン インコーポレーティッド | キナーゼのビ−アリールメタ−ピリミジン阻害剤 |
| US8604042B2 (en) | 2005-11-01 | 2013-12-10 | Targegen, Inc. | Bi-aryl meta-pyrimidine inhibitors of kinases |
| US8133900B2 (en) | 2005-11-01 | 2012-03-13 | Targegen, Inc. | Use of bi-aryl meta-pyrimidine inhibitors of kinases |
| JP5249772B2 (ja) * | 2005-11-22 | 2013-07-31 | メルク・シャープ・アンド・ドーム・コーポレーション | キナーゼの阻害剤として有用な三環式化合物 |
| SG10202003901UA (en) | 2005-12-13 | 2020-05-28 | Incyte Holdings Corp | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors |
| KR20080110998A (ko) * | 2006-01-30 | 2008-12-22 | 엑셀리시스, 인코포레이티드 | Ｊａｋ２ 조절자로서 ４아릴２아미노피리미딘 또는 4아릴２아미노알킬피리미딘 및 이들을 포함하는 약제학적 조성물 |
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| GB9523675D0 (en) | 1995-11-20 | 1996-01-24 | Celltech Therapeutics Ltd | Chemical compounds |
| WO2001062233A2 (en) * | 2000-02-25 | 2001-08-30 | F. Hoffmann La Roche Ag | Adenosine receptor modulators |
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| CA2441733A1 (en) * | 2001-03-29 | 2002-10-10 | Vertex Pharmaceuticals Incorporated | Inhibitors of c-jun n-terminal kinases (jnk) and other protein kinases |
| WO2002083668A1 (en) * | 2001-04-10 | 2002-10-24 | Vertex Pharmaceuticals Incorporated | Isoxaxole derivatives as inhibitors of src and other protein kinases |
| CA2450769A1 (en) | 2001-06-15 | 2002-12-27 | Vertex Pharmaceuticals Incorporated | 5-(2-aminopyrimidin-4-yl) benzisoxazoles as protein kinase inhibitors |
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- 2003-11-04 JP JP2004550483A patent/JP4688498B2/ja not_active Expired - Fee Related
- 2003-11-04 WO PCT/US2003/035163 patent/WO2004041814A1/en not_active Ceased
- 2003-11-04 DE DE60316013T patent/DE60316013T2/de not_active Expired - Lifetime
- 2003-11-04 AT AT03786582T patent/ATE371656T1/de not_active IP Right Cessation
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- 2003-11-04 AU AU2003295396A patent/AU2003295396B2/en not_active Ceased
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| AU2003295396A1 (en) | 2004-06-07 |
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| EP1562938B1 (en) | 2007-08-29 |
| DE60316013T2 (de) | 2008-05-29 |
| ATE371656T1 (de) | 2007-09-15 |
| JP4688498B2 (ja) | 2011-05-25 |
| WO2004041814A1 (en) | 2004-05-21 |
| DE60316013D1 (de) | 2007-10-11 |
| CA2506773A1 (en) | 2004-05-21 |
| JP2006514006A (ja) | 2006-04-27 |
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