AU2003219803B8 - Method of treating TRX mediated diseases - Google Patents

Method of treating TRX mediated diseases Download PDF

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Publication number
AU2003219803B8
AU2003219803B8 AU2003219803A AU2003219803A AU2003219803B8 AU 2003219803 B8 AU2003219803 B8 AU 2003219803B8 AU 2003219803 A AU2003219803 A AU 2003219803A AU 2003219803 A AU2003219803 A AU 2003219803A AU 2003219803 B8 AU2003219803 B8 AU 2003219803B8
Authority
AU
Australia
Prior art keywords
hdac inhibitor
trx
binding
group
thioredoxin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2003219803A
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English (en)
Other versions
AU2003219803A1 (en
AU2003219803B2 (en
Inventor
Lisa M. Butler
Paul A. Marks
Victoria M. Richon
Richard A. Rifkind
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Memorial Sloan Kettering Cancer Center
Original Assignee
Memorial Sloan Kettering Cancer Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Memorial Sloan Kettering Cancer Center filed Critical Memorial Sloan Kettering Cancer Center
Publication of AU2003219803A1 publication Critical patent/AU2003219803A1/en
Application granted granted Critical
Publication of AU2003219803B2 publication Critical patent/AU2003219803B2/en
Publication of AU2003219803B8 publication Critical patent/AU2003219803B8/en
Priority to AU2005227400A priority Critical patent/AU2005227400B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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AU2003219803A 2002-02-15 2003-02-14 Method of treating TRX mediated diseases Ceased AU2003219803B8 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2005227400A AU2005227400B2 (en) 2002-02-15 2005-10-28 Method of Treating TRX Mediated Diseases

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35738302P 2002-02-15 2002-02-15
US60/357,383 2002-02-15
PCT/US2003/004924 WO2003070188A2 (en) 2002-02-15 2003-02-14 Method of treating trx mediated diseases

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2005227400A Division AU2005227400B2 (en) 2002-02-15 2005-10-28 Method of Treating TRX Mediated Diseases

Publications (3)

Publication Number Publication Date
AU2003219803A1 AU2003219803A1 (en) 2003-09-09
AU2003219803B2 AU2003219803B2 (en) 2005-07-28
AU2003219803B8 true AU2003219803B8 (en) 2005-08-25

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ID=27757609

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003219803A Ceased AU2003219803B8 (en) 2002-02-15 2003-02-14 Method of treating TRX mediated diseases

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US (3) US20030235588A1 (enExample)
EP (1) EP1482962A4 (enExample)
JP (1) JP2005525345A (enExample)
AU (1) AU2003219803B8 (enExample)
CA (1) CA2476434A1 (enExample)
WO (1) WO2003070188A2 (enExample)

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BR0014254A (pt) * 1999-09-08 2002-08-27 Sloan Kettering Inst Cancer Nova classe de agentes de citodiferenciação e inibidores de desacetilase de histona, e métodos de uso dos mesmos
WO2002060933A2 (en) * 2001-01-30 2002-08-08 The Provost, Fellows And Scholars Of The College Of The Holy And Unidivided Trinity Of Queen Elizabeht Thioredoxin derived from h. pylori, which is capable of inhibiting nf-kappa b activation
EP1443928B1 (en) * 2001-10-16 2011-07-27 Sloan-Kettering Institute For Cancer Research Treatment of neurodegenerative diseases and cancer of the brain
US20030235588A1 (en) * 2002-02-15 2003-12-25 Richon Victoria M. Method of treating TRX mediated diseases
US20060276547A1 (en) * 2002-03-04 2006-12-07 Bacopoulos Nicholas G Methods of treating cancer with HDAC inhibitors
US7148257B2 (en) * 2002-03-04 2006-12-12 Merck Hdac Research, Llc Methods of treating mesothelioma with suberoylanilide hydroxamic acid
MXPA04008577A (es) * 2002-03-04 2005-07-13 Aton Pharma Inc Metodos para inducir diferenciacion terminal.
US20040132825A1 (en) * 2002-03-04 2004-07-08 Bacopoulos Nicholas G. Methods of treating cancer with HDAC inhibitors
US7456219B2 (en) * 2002-03-04 2008-11-25 Merck Hdac Research, Llc Polymorphs of suberoylanilide hydroxamic acid
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