AU2002222695A1 - Novel 4'-demethyl-4'-o-substituted-1-deoxypodophyllotoxin derivative and geometric isomer thereof, process for the preparation thereof and anti-cancer composition comprising the same - Google Patents

Novel 4'-demethyl-4'-o-substituted-1-deoxypodophyllotoxin derivative and geometric isomer thereof, process for the preparation thereof and anti-cancer composition comprising the same

Info

Publication number
AU2002222695A1
AU2002222695A1 AU2002222695A AU2269502A AU2002222695A1 AU 2002222695 A1 AU2002222695 A1 AU 2002222695A1 AU 2002222695 A AU2002222695 A AU 2002222695A AU 2269502 A AU2269502 A AU 2269502A AU 2002222695 A1 AU2002222695 A1 AU 2002222695A1
Authority
AU
Australia
Prior art keywords
demethyl
substituted
novel
preparation
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002222695A
Other languages
English (en)
Inventor
Byung-Zun Ahn
Song-Bae Kim
Yong Kim
Young-Jae You
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR10-2001-0040806A external-priority patent/KR100433679B1/ko
Application filed by Individual filed Critical Individual
Publication of AU2002222695A1 publication Critical patent/AU2002222695A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AU2002222695A 2000-11-20 2001-11-19 Novel 4'-demethyl-4'-o-substituted-1-deoxypodophyllotoxin derivative and geometric isomer thereof, process for the preparation thereof and anti-cancer composition comprising the same Abandoned AU2002222695A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
KR20000069004 2000-11-20
KR0069004 2000-11-20
KR0140806 2001-07-09
KR10-2001-0040806A KR100433679B1 (ko) 2000-11-20 2001-07-09 신규의 4'-데메틸-4'-ｏ-치환-1-데옥시포도필로톡신유도체 및 그의 기하 이성체, 그의 제조방법 및 그를포함하는 항암제
PCT/KR2001/001972 WO2002040489A1 (en) 2000-11-20 2001-11-19 Novel 4'-demethyl-4'-o-substituted-1-deoxypodophyllotoxin derivative and geometric isomer thereof, process for the preparation thereof and anti-cancer composition comprising the same

Publications (1)

Publication Number Publication Date
AU2002222695A1 true AU2002222695A1 (en) 2002-05-27

Family

ID=26638551

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002222695A Abandoned AU2002222695A1 (en) 2000-11-20 2001-11-19 Novel 4'-demethyl-4'-o-substituted-1-deoxypodophyllotoxin derivative and geometric isomer thereof, process for the preparation thereof and anti-cancer composition comprising the same

Country Status (10)

Country Link
US (1) US6894075B2 (de)
EP (1) EP1335922B1 (de)
JP (1) JP4024148B2 (de)
CN (1) CN1256336C (de)
AT (1) ATE339423T1 (de)
AU (1) AU2002222695A1 (de)
DE (1) DE60123105T2 (de)
DK (1) DK1335922T3 (de)
ES (1) ES2271120T3 (de)
WO (1) WO2002040489A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0102168D0 (sv) * 2001-06-19 2001-06-19 Karolinska Innovations Ab New use and new compounds
CA2803646A1 (en) 2010-07-02 2012-01-05 Angiochem Inc. Short and d-amino acid-containing polypeptides for therapeutic conjugates and uses thereof
CN102070645B (zh) * 2011-01-07 2015-04-22 兰州大学 一种脱氧鬼臼毒素类化合物及其制备与应用
CN102260273B (zh) * 2011-05-13 2015-04-22 兰州大学 脱氧鬼臼与5-氟尿嘧啶的拼合物及其制备与用途
CN103214495A (zh) * 2013-03-29 2013-07-24 西南交通大学 抗癌用4’-去甲基-4’-氧-环丁甲酰基-去氧鬼臼毒及其制备方法
KR102378151B1 (ko) 2020-05-11 2022-03-24 주식회사 제이앤씨사이언스 베타-아포피크로포도필린의 신규한 유도체

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH454169A (de) * 1964-08-12 1968-04-15 Sandoz Ag Verfahren zur Herstellung von neuen Podophyllotoxin-Derivaten
IL119749A (en) * 1995-12-04 2001-03-19 Nippon Kayaku Kk Process for producing etoposide
US6051721A (en) * 1997-10-02 2000-04-18 The Board Of Regents Of The University Of Nebraska Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis

Also Published As

Publication number Publication date
ATE339423T1 (de) 2006-10-15
US6894075B2 (en) 2005-05-17
CN1474822A (zh) 2004-02-11
DK1335922T3 (da) 2007-01-15
US20040044058A1 (en) 2004-03-04
ES2271120T3 (es) 2007-04-16
CN1256336C (zh) 2006-05-17
EP1335922A1 (de) 2003-08-20
WO2002040489A1 (en) 2002-05-23
DE60123105D1 (de) 2006-10-26
EP1335922B1 (de) 2006-09-13
EP1335922A4 (de) 2004-08-11
JP2004513949A (ja) 2004-05-13
DE60123105T2 (de) 2007-04-26
JP4024148B2 (ja) 2007-12-19

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