AU2001248849A1 - Estra-1,3,5(10)-triene derivatives - Google Patents

Estra-1,3,5(10)-triene derivatives

Info

Publication number
AU2001248849A1
AU2001248849A1 AU2001248849A AU4884901A AU2001248849A1 AU 2001248849 A1 AU2001248849 A1 AU 2001248849A1 AU 2001248849 A AU2001248849 A AU 2001248849A AU 4884901 A AU4884901 A AU 4884901A AU 2001248849 A1 AU2001248849 A1 AU 2001248849A1
Authority
AU
Australia
Prior art keywords
estra
triene derivatives
triene
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001248849A
Inventor
Tsutomu Agatsuma
Shiro Akinaga
Nobuyoshi Amishiro
Kozue Hayashi
Yoji Ino
Mayumi Miyata
Chikara Murakata
Takeshi Takahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of AU2001248849A1 publication Critical patent/AU2001248849A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
AU2001248849A 2000-04-24 2001-04-24 Estra-1,3,5(10)-triene derivatives Abandoned AU2001248849A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000-121960 2000-04-24
JP2000121960 2000-04-24
PCT/JP2001/003505 WO2001081364A1 (en) 2000-04-24 2001-04-24 Estra-1,3,5(10)-triene derivatives

Publications (1)

Publication Number Publication Date
AU2001248849A1 true AU2001248849A1 (en) 2001-11-07

Family

ID=18632506

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001248849A Abandoned AU2001248849A1 (en) 2000-04-24 2001-04-24 Estra-1,3,5(10)-triene derivatives

Country Status (5)

Country Link
US (1) US6953785B2 (en)
EP (1) EP1284272A4 (en)
JP (1) JPWO2001081364A1 (en)
AU (1) AU2001248849A1 (en)
WO (1) WO2001081364A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040214807A1 (en) * 1993-08-06 2004-10-28 D'amato Robert J. Estrogenic compounds as anti-mitotic agents
US20050192258A1 (en) * 2000-08-18 2005-09-01 Agoston Gregory E. Antiangiogenic agents
US6995278B2 (en) * 2000-08-18 2006-02-07 Entre Med, Inc. Antiangiogenic agents
MXPA04004802A (en) * 2001-11-21 2004-08-11 Sterix Ltd 1,2,4-triazole derivatives containing a sulphamate group as aromatase inhibitors.
JPWO2004035089A1 (en) * 2002-10-09 2006-02-09 協和醗酵工業株式会社 Treatment for hormone-dependent cancer
GB0306717D0 (en) * 2003-03-24 2003-04-30 Sterix Ltd Compound
EP1608671B1 (en) * 2003-03-24 2010-01-06 Sterix Limited Oestrogen derivatives as inhibitors of steroid sulphatase
EP1633367A2 (en) * 2003-05-28 2006-03-15 EntreMed, Inc. Antiangiogenic agents
US20070004689A1 (en) * 2004-03-12 2007-01-04 Agoston Gregory E Antiangiogenic agents
CA2558014A1 (en) 2004-03-12 2005-09-29 Entremed, Inc. Antiangiogenic agents
DE102004025985A1 (en) * 2004-05-21 2005-12-15 Schering Ag Estriol and estetrol prodrugs
DE102004025966A1 (en) * 2004-05-21 2005-12-15 Schering Ag Estradiol prodrugs
GB0421106D0 (en) * 2004-09-22 2004-10-27 Sterix Ltd Compound
CA2587448A1 (en) * 2004-11-29 2006-06-01 Entremed, Inc. A method of administering anti-angiogenic agents and a method of treating disease using same
CA2646065C (en) 2006-03-20 2014-01-14 Entremed, Inc. Disease modifying anti-arthritic activity of 2-methoxyestradiol
US20080051380A1 (en) 2006-08-25 2008-02-28 Auerbach Alan H Methods and compositions for treating cancer
AP2014008179A0 (en) * 2012-07-10 2014-12-31 Bayer Pharma AG 3-Substituted estra-1,3,5(10), 16-tetraene derivativess, methods for the production thereof, pharmaceutical preparations containing same, and use thereof for the production of medicaments
BR112019001398A2 (en) 2016-07-29 2019-05-07 Janssen Pharmaceutica Nv Methods for Prostate Cancer Treatment

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9625334D0 (en) 1996-12-05 1997-01-22 Imperial College Compound
GB9118478D0 (en) * 1991-08-29 1991-10-16 Imperial College Steroid sulphatase inhibitors
GB9118465D0 (en) * 1991-08-29 1991-10-16 Imperial College Steroid sulphatase inhibitors
US5556847A (en) * 1994-10-27 1996-09-17 Duquesne University Of The Holy Ghost Methods of effecting memory enhancement mediated by steroid sulfatase inhibitors
US5571933A (en) * 1994-11-17 1996-11-05 Duquesne University Of The Holy Ghost Derivatives of estra 1,3,5(10)triene-17-one, 3-amino compounds and their use
CN1131238C (en) * 1996-09-12 2003-12-17 帝国脏器制药株式会社 3-substituted-d-homo-1,3,5 (10)-estratriene derivatives
US5763492A (en) * 1996-10-01 1998-06-09 Duguesne University Of The Holy Ghost Methods for effecting memory enhancement mediated by non-steroidal sulfatase inhibitors
US5763432A (en) * 1997-01-29 1998-06-09 Sri International Steriod inhibitors of estrone sulfatase and associated pharmaceutical compositions and methods of use
DE19712488A1 (en) * 1997-03-25 1998-10-01 Knoell Hans Forschung Ev Steroid sulfamates, processes for their preparation and use thereof
US6288050B1 (en) 1997-07-18 2001-09-11 Duquesne University Of The Holy Ghost Steroid sulfatase inhibitors and methods for making and using the same
US5880115A (en) * 1997-07-18 1999-03-09 Duquesne University Of The Holy Ghost Steroid sulfatase inhibitors and methods for making and using the same
GB2331987B (en) 1997-12-04 2002-11-27 Imperial College Polycyclic sulphamate inhibitors of oestrone sulphatase
GB2331988B (en) 1997-12-04 2003-04-16 Imperial College Polycyclic sulphamate inhibitors or oestrone sulphatase
US6046186A (en) * 1997-12-24 2000-04-04 Sri International Estrone sulfamate inhibitors of estrone sulfatase, and associated pharmaceutical compositions and methods of use
US6054446A (en) 1997-12-24 2000-04-25 Sri International Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
WO2000053620A1 (en) 1999-03-10 2000-09-14 Nippon Organon K. K. Novel estradiol derivatives
DE19943708B4 (en) 1999-09-08 2007-12-20 Bayer Schering Pharma Ag New C13-substituted Estra-1,3,5 (10) -trien-3-yl-sulfamates, processes for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP1284272A1 (en) 2003-02-19
WO2001081364A1 (en) 2001-11-01
EP1284272A4 (en) 2003-09-10
JPWO2001081364A1 (en) 2004-01-08
US20030216362A1 (en) 2003-11-20
US6953785B2 (en) 2005-10-11

Similar Documents

Publication Publication Date Title
AU2001230026A1 (en) 2,4-diaminothiazole derivatives
MXPA01011070A (en) Steroid derivatives.
AU2001260939A1 (en) Single seed sortation
AU2001243462A1 (en) Improved thoraco-lumbo-sacral orthosis
AU2001280099A1 (en) 4-acylaminopyrazole derivatives
IL152448A0 (en) 3-nitrogen-6, 7-dioxygen steroid derivatives and pharmaceutical compositions containing the same
AU2001230584A1 (en) 1h-imidazopyridine derivatives
AU2001258341A1 (en) 8beta-hydrocarbyl-substituted estratrienes for use as selective estrogens
AU2001284934A1 (en) Steroid derived antibiotics
AU2001248849A1 (en) Estra-1,3,5(10)-triene derivatives
AU2001230537A1 (en) Pyridoxazine derivatives
AU1405101A (en) Masks
AU2001281802A1 (en) 6-phenylpyrrolopyrimidinedione derivatives
AU2001278790A1 (en) 1h-imidazopyridine derivatives
AU9750398A (en) D-homo-9,10-secocholesta-23-yne-3,25-diol derivatives
EP1144431A3 (en) 16-hydroxyestratrienes as selective estrogens
AU6594401A (en) 6-heterocyclyl-3-oxo-3,4-dihydro-quinoxalines
AU2001254661A1 (en) Aminosulfonylbiphenyl derivatives
AU2001230565A1 (en) Perfluoroisopropylbenzene derivatives
AU2001220281A1 (en) Rollerboard for road-skiing
AU3883800A (en) Hob-bp2h compositions, methods and uses thereof
AU2001262489A1 (en) Triterpenoid derivatives
AU2002224133A1 (en) Remedies for dermatophytosis
AU2001252671A1 (en) Pyridobenzodiazine derivatives and processes for the preparation thereof
AU1110699A (en) Estra-1,3,5(10)-triene-7alpha-thioethers