DK1335922T3 - Fremgangsmåde til fremstilling af 4'-demethyl-4'-O-substituerede 1-deoxypodophyllotoxinderivater og geometriske isomerer deraf og anticancersammensætninger, der indeholder samme - Google Patents

Fremgangsmåde til fremstilling af 4'-demethyl-4'-O-substituerede 1-deoxypodophyllotoxinderivater og geometriske isomerer deraf og anticancersammensætninger, der indeholder samme

Info

Publication number
DK1335922T3
DK1335922T3 DK01996542T DK01996542T DK1335922T3 DK 1335922 T3 DK1335922 T3 DK 1335922T3 DK 01996542 T DK01996542 T DK 01996542T DK 01996542 T DK01996542 T DK 01996542T DK 1335922 T3 DK1335922 T3 DK 1335922T3
Authority
DK
Denmark
Prior art keywords
demethyl
substituted
preparation
deoxypodophyllotoxin
same
Prior art date
Application number
DK01996542T
Other languages
English (en)
Inventor
Song-Bae Kim
Byung-Zun Ahn
Yong Kim
Young-Jae You
Original Assignee
Kim Song Bae
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR10-2001-0040806A external-priority patent/KR100433679B1/ko
Application filed by Kim Song Bae filed Critical Kim Song Bae
Application granted granted Critical
Publication of DK1335922T3 publication Critical patent/DK1335922T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK01996542T 2000-11-20 2001-11-19 Fremgangsmåde til fremstilling af 4'-demethyl-4'-O-substituerede 1-deoxypodophyllotoxinderivater og geometriske isomerer deraf og anticancersammensætninger, der indeholder samme DK1335922T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20000069004 2000-11-20
KR10-2001-0040806A KR100433679B1 (ko) 2000-11-20 2001-07-09 신규의 4'-데메틸-4'-ｏ-치환-1-데옥시포도필로톡신유도체 및 그의 기하 이성체, 그의 제조방법 및 그를포함하는 항암제

Publications (1)

Publication Number Publication Date
DK1335922T3 true DK1335922T3 (da) 2007-01-15

Family

ID=26638551

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01996542T DK1335922T3 (da) 2000-11-20 2001-11-19 Fremgangsmåde til fremstilling af 4'-demethyl-4'-O-substituerede 1-deoxypodophyllotoxinderivater og geometriske isomerer deraf og anticancersammensætninger, der indeholder samme

Country Status (10)

Country Link
US (1) US6894075B2 (da)
EP (1) EP1335922B1 (da)
JP (1) JP4024148B2 (da)
CN (1) CN1256336C (da)
AT (1) ATE339423T1 (da)
AU (1) AU2002222695A1 (da)
DE (1) DE60123105T2 (da)
DK (1) DK1335922T3 (da)
ES (1) ES2271120T3 (da)
WO (1) WO2002040489A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0102168D0 (sv) 2001-06-19 2001-06-19 Karolinska Innovations Ab New use and new compounds
CA2803646A1 (en) 2010-07-02 2012-01-05 Angiochem Inc. Short and d-amino acid-containing polypeptides for therapeutic conjugates and uses thereof
CN102070645B (zh) * 2011-01-07 2015-04-22 兰州大学 一种脱氧鬼臼毒素类化合物及其制备与应用
CN102260273B (zh) * 2011-05-13 2015-04-22 兰州大学 脱氧鬼臼与5-氟尿嘧啶的拼合物及其制备与用途
CN103214495A (zh) * 2013-03-29 2013-07-24 西南交通大学 抗癌用4’-去甲基-4’-氧-环丁甲酰基-去氧鬼臼毒及其制备方法
KR102378151B1 (ko) 2020-05-11 2022-03-24 주식회사 제이앤씨사이언스 베타-아포피크로포도필린의 신규한 유도체

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH454169A (de) * 1964-08-12 1968-04-15 Sandoz Ag Verfahren zur Herstellung von neuen Podophyllotoxin-Derivaten
IL119749A (en) 1995-12-04 2001-03-19 Nippon Kayaku Kk Process for producing etoposide
US6051721A (en) 1997-10-02 2000-04-18 The Board Of Regents Of The University Of Nebraska Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis

Also Published As

Publication number Publication date
DE60123105T2 (de) 2007-04-26
WO2002040489A1 (en) 2002-05-23
JP4024148B2 (ja) 2007-12-19
US6894075B2 (en) 2005-05-17
EP1335922A1 (en) 2003-08-20
DE60123105D1 (de) 2006-10-26
JP2004513949A (ja) 2004-05-13
US20040044058A1 (en) 2004-03-04
ATE339423T1 (de) 2006-10-15
EP1335922B1 (en) 2006-09-13
CN1474822A (zh) 2004-02-11
EP1335922A4 (en) 2004-08-11
ES2271120T3 (es) 2007-04-16
AU2002222695A1 (en) 2002-05-27
CN1256336C (zh) 2006-05-17

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