AU2002215012A1 - Process for the production of racemic thioctic acid - Google Patents

Process for the production of racemic thioctic acid

Info

Publication number
AU2002215012A1
AU2002215012A1 AU2002215012A AU1501202A AU2002215012A1 AU 2002215012 A1 AU2002215012 A1 AU 2002215012A1 AU 2002215012 A AU2002215012 A AU 2002215012A AU 1501202 A AU1501202 A AU 1501202A AU 2002215012 A1 AU2002215012 A1 AU 2002215012A1
Authority
AU
Australia
Prior art keywords
group
racemic
acid
substituents
thioctic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002215012A
Other languages
English (en)
Inventor
Francesco Corcella
Stefano Maiorana
Annibale Salvi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorio Chimico Internazionale SpA
Original Assignee
Laboratorio Chimico Internazionale SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorio Chimico Internazionale SpA filed Critical Laboratorio Chimico Internazionale SpA
Publication of AU2002215012A1 publication Critical patent/AU2002215012A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
AU2002215012A 2000-10-10 2001-10-08 Process for the production of racemic thioctic acid Abandoned AU2002215012A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI2000A002186 2000-10-10
IT2000MI002186A IT1319194B1 (it) 2000-10-10 2000-10-10 Processo per la produzione dell'acido tiottico racemo.
PCT/EP2001/011577 WO2002030917A2 (en) 2000-10-10 2001-10-08 Process for the production of racemic thioctic acid

Publications (1)

Publication Number Publication Date
AU2002215012A1 true AU2002215012A1 (en) 2002-04-22

Family

ID=11445935

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002215012A Abandoned AU2002215012A1 (en) 2000-10-10 2001-10-08 Process for the production of racemic thioctic acid

Country Status (11)

Country Link
US (1) US6844450B2 (es)
EP (1) EP1330449B1 (es)
JP (1) JP4257572B2 (es)
KR (1) KR100822533B1 (es)
AT (1) ATE269319T1 (es)
AU (1) AU2002215012A1 (es)
CZ (1) CZ301711B6 (es)
DE (1) DE60103923T2 (es)
ES (1) ES2222399T3 (es)
IT (1) IT1319194B1 (es)
WO (1) WO2002030917A2 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10137381A1 (de) * 2001-07-31 2003-02-13 Viatris Gmbh Neue Modifikationen des Trometamolsalzes der R-Thioctsäure sowie Verfahren zu ihrer Herstellung
DE10201464B4 (de) * 2002-01-16 2005-06-16 Viatris Gmbh & Co. Kg Verfahren zur Herstellung reiner Thioctsäure
ITMI20030831A1 (it) 2003-04-22 2004-10-23 Laboratorio Chimico Int Spa Sale basico dell'acido tiottico con la l-carnitina.
ITMI20061024A1 (it) 2006-05-25 2007-11-26 Eurand Pharmaceuticals Ltd Pellet a base di acido lipoico
CN102558142A (zh) * 2010-12-23 2012-07-11 重庆药友制药有限责任公司 一种α-硫辛酸原料药的制备方法
CN106349323B (zh) * 2016-08-25 2018-04-10 桂林益天成生物科技有限公司 水解积雪草总皂苷制备积雪草皂苷元的方法
CN108774209A (zh) * 2018-08-03 2018-11-09 苏州富士莱医药股份有限公司 一种采用管式反应器制备硫辛酸乙酯的方法
CN112574171A (zh) * 2020-12-15 2021-03-30 南京新百药业有限公司 一种硫辛酸的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA608575A (en) * 1960-11-15 S. Acker Donald Preparation of lipoic acid
US2792406A (en) * 1954-06-01 1957-05-14 Du Pont Process of preparing alpha-lipoic acid using dichlorooctanoate and metal disulfide
DE3814163A1 (de) * 1988-04-27 1989-11-09 Rhein Chemie Rheinau Gmbh Verfahren zur herstellung von disulfiden
DE4342619A1 (de) * 1993-12-14 1995-06-22 Bayer Ag Verbessertes Verfahren zur Herstellung von 2,2'-Dinitrodiphenyldisulfid
GB9510858D0 (en) * 1995-05-30 1995-07-26 Chiroscience Ltd Process for preparing lipoic acid
DE19533881A1 (de) * 1995-09-13 1997-03-20 Dresden Arzneimittel Herstellung und Verwendung der reinen Enantiomere der 8-Chlor-6-sulfonyloxy-octansäuren und ihrer Alkylester und der reinen Enantiomere der 6,8-Dichlor-octansäure und ihrer Alkylester

Also Published As

Publication number Publication date
JP2004511475A (ja) 2004-04-15
US20040030157A1 (en) 2004-02-12
KR20030070002A (ko) 2003-08-27
WO2002030917A2 (en) 2002-04-18
IT1319194B1 (it) 2003-09-26
DE60103923T2 (de) 2005-06-30
EP1330449A2 (en) 2003-07-30
JP4257572B2 (ja) 2009-04-22
EP1330449B1 (en) 2004-06-16
CZ301711B6 (cs) 2010-06-02
DE60103923D1 (de) 2004-07-22
ATE269319T1 (de) 2004-07-15
ES2222399T3 (es) 2005-02-01
ITMI20002186A0 (it) 2000-10-10
US6844450B2 (en) 2005-01-18
ITMI20002186A1 (it) 2002-04-10
KR100822533B1 (ko) 2008-04-16
WO2002030917A3 (en) 2002-07-25

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