AU2001251453A1 - Device for detecting analytes related to sample ph - Google Patents
Device for detecting analytes related to sample phInfo
- Publication number
- AU2001251453A1 AU2001251453A1 AU2001251453A AU5145301A AU2001251453A1 AU 2001251453 A1 AU2001251453 A1 AU 2001251453A1 AU 2001251453 A AU2001251453 A AU 2001251453A AU 5145301 A AU5145301 A AU 5145301A AU 2001251453 A1 AU2001251453 A1 AU 2001251453A1
- Authority
- AU
- Australia
- Prior art keywords
- holding structure
- analyte
- sample
- kit
- assay
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000003556 assay Methods 0.000 claims description 82
- 210000003296 saliva Anatomy 0.000 claims description 71
- ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 claims description 70
- 239000012491 analyte Substances 0.000 claims description 66
- 238000012360 testing method Methods 0.000 claims description 61
- 239000000523 sample Substances 0.000 claims description 59
- 229960003920 cocaine Drugs 0.000 claims description 36
- 239000000700 radioactive tracer Substances 0.000 claims description 29
- 239000012488 sample solution Substances 0.000 claims description 19
- 210000004369 blood Anatomy 0.000 claims description 17
- 239000008280 blood Substances 0.000 claims description 17
- 239000000463 material Substances 0.000 claims description 16
- 238000003018 immunoassay Methods 0.000 claims description 12
- MYWUZJCMWCOHBA-VIFPVBQESA-N methamphetamine Chemical compound CN[C@@H](C)CC1=CC=CC=C1 MYWUZJCMWCOHBA-VIFPVBQESA-N 0.000 claims description 12
- 229960001252 methamphetamine Drugs 0.000 claims description 12
- 238000001139 pH measurement Methods 0.000 claims description 10
- 229920002678 cellulose Polymers 0.000 claims description 6
- 239000001913 cellulose Substances 0.000 claims description 6
- 239000002184 metal Substances 0.000 claims description 6
- 229910052751 metal Inorganic materials 0.000 claims description 6
- 239000004033 plastic Substances 0.000 claims description 6
- 230000004888 barrier function Effects 0.000 claims description 4
- 210000001124 body fluid Anatomy 0.000 claims description 4
- 230000002209 hydrophobic effect Effects 0.000 claims description 4
- 150000002894 organic compounds Chemical class 0.000 claims description 4
- UDSAIICHUKSCKT-UHFFFAOYSA-N bromophenol blue Chemical compound C1=C(Br)C(O)=C(Br)C=C1C1(C=2C=C(Br)C(O)=C(Br)C=2)C2=CC=CC=C2S(=O)(=O)O1 UDSAIICHUKSCKT-UHFFFAOYSA-N 0.000 claims description 3
- STZCRXQWRGQSJD-GEEYTBSJSA-M methyl orange Chemical compound [Na+].C1=CC(N(C)C)=CC=C1\N=N\C1=CC=C(S([O-])(=O)=O)C=C1 STZCRXQWRGQSJD-GEEYTBSJSA-M 0.000 claims description 3
- 229940012189 methyl orange Drugs 0.000 claims description 3
- CEQFOVLGLXCDCX-WUKNDPDISA-N methyl red Chemical compound C1=CC(N(C)C)=CC=C1\N=N\C1=CC=CC=C1C(O)=O CEQFOVLGLXCDCX-WUKNDPDISA-N 0.000 claims description 3
- 231100000614 poison Toxicity 0.000 claims description 3
- 239000003440 toxic substance Substances 0.000 claims description 3
- 239000010839 body fluid Substances 0.000 claims description 2
- 238000011109 contamination Methods 0.000 claims description 2
- 208000015181 infectious disease Diseases 0.000 claims description 2
- 230000002458 infectious effect Effects 0.000 claims description 2
- 231100000252 nontoxic Toxicity 0.000 claims description 2
- 230000003000 nontoxic effect Effects 0.000 claims description 2
- 238000001514 detection method Methods 0.000 claims 8
- 239000003086 colorant Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 description 45
- 229940079593 drug Drugs 0.000 description 44
- 239000003153 chemical reaction reagent Substances 0.000 description 20
- 210000002381 plasma Anatomy 0.000 description 19
- 239000012528 membrane Substances 0.000 description 12
- 239000011230 binding agent Substances 0.000 description 8
- 238000000034 method Methods 0.000 description 6
- 239000000126 substance Substances 0.000 description 6
- 230000036765 blood level Effects 0.000 description 5
- 238000012552 review Methods 0.000 description 5
- 102000004190 Enzymes Human genes 0.000 description 4
- 108090000790 Enzymes Proteins 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 4
- 239000000427 antigen Substances 0.000 description 4
- 102000036639 antigens Human genes 0.000 description 4
- 108091007433 antigens Proteins 0.000 description 4
- 238000003255 drug test Methods 0.000 description 4
- 239000012530 fluid Substances 0.000 description 4
- 238000005259 measurement Methods 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 239000000020 Nitrocellulose Substances 0.000 description 3
- 239000012042 active reagent Substances 0.000 description 3
- 238000004364 calculation method Methods 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 229920001220 nitrocellulos Polymers 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 230000002285 radioactive effect Effects 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 239000004677 Nylon Substances 0.000 description 2
- 101710120037 Toxin CcdB Proteins 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 238000006664 bond formation reaction Methods 0.000 description 2
- OROGSEYTTFOCAN-DNJOTXNNSA-N codeine Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC OROGSEYTTFOCAN-DNJOTXNNSA-N 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 238000002967 competitive immunoassay Methods 0.000 description 2
- 230000009260 cross reactivity Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 230000002255 enzymatic effect Effects 0.000 description 2
- 239000003365 glass fiber Substances 0.000 description 2
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 description 2
- 229920001778 nylon Polymers 0.000 description 2
- 239000004417 polycarbonate Substances 0.000 description 2
- 229920000515 polycarbonate Polymers 0.000 description 2
- 229920002981 polyvinylidene fluoride Polymers 0.000 description 2
- 239000012070 reactive reagent Substances 0.000 description 2
- 102000005962 receptors Human genes 0.000 description 2
- 108020003175 receptors Proteins 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- 238000012935 Averaging Methods 0.000 description 1
- KZFBHCCLJSAHBQ-UHFFFAOYSA-N Benzoylecgonine Natural products CN1C2CCC1C(C(C2)OC(=C)c3ccccc3)C(=O)O KZFBHCCLJSAHBQ-UHFFFAOYSA-N 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 235000012766 Cannabis sativa ssp. sativa var. sativa Nutrition 0.000 description 1
- 235000012765 Cannabis sativa ssp. sativa var. spontanea Nutrition 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 238000013096 assay test Methods 0.000 description 1
- 239000012888 bovine serum Substances 0.000 description 1
- RMRJXGBAOAMLHD-IHFGGWKQSA-N buprenorphine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)CN2CC1CC1 RMRJXGBAOAMLHD-IHFGGWKQSA-N 0.000 description 1
- 229960001736 buprenorphine Drugs 0.000 description 1
- 238000011088 calibration curve Methods 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229960004126 codeine Drugs 0.000 description 1
- 238000012875 competitive assay Methods 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 230000000875 corresponding effect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 231100000673 dose–response relationship Toxicity 0.000 description 1
- 238000009513 drug distribution Methods 0.000 description 1
- GVGYEFKIHJTNQZ-RFQIPJPRSA-N ecgonine benzoate Chemical compound O([C@@H]1[C@@H]([C@H]2CC[C@@H](C1)N2C)C(O)=O)C(=O)C1=CC=CC=C1 GVGYEFKIHJTNQZ-RFQIPJPRSA-N 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- -1 enzymes Chemical class 0.000 description 1
- 229960004756 ethanol Drugs 0.000 description 1
- 210000000416 exudates and transudate Anatomy 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 238000002290 gas chromatography-mass spectrometry Methods 0.000 description 1
- 239000000383 hazardous chemical Substances 0.000 description 1
- OROGSEYTTFOCAN-UHFFFAOYSA-N hydrocodone Natural products C1C(N(CCC234)C)C2C=CC(O)C3OC2=C4C1=CC=C2OC OROGSEYTTFOCAN-UHFFFAOYSA-N 0.000 description 1
- GPRLSGONYQIRFK-UHFFFAOYSA-N hydron Chemical compound [H+] GPRLSGONYQIRFK-UHFFFAOYSA-N 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229960005181 morphine Drugs 0.000 description 1
- 229960004715 morphine sulfate Drugs 0.000 description 1
- GRVOTVYEFDAHCL-RTSZDRIGSA-N morphine sulfate pentahydrate Chemical compound O.O.O.O.O.OS(O)(=O)=O.O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O.O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O GRVOTVYEFDAHCL-RTSZDRIGSA-N 0.000 description 1
- JTJMJGYZQZDUJJ-UHFFFAOYSA-N phencyclidine Chemical compound C1CCCCN1C1(C=2C=CC=CC=2)CCCCC1 JTJMJGYZQZDUJJ-UHFFFAOYSA-N 0.000 description 1
- 229950010883 phencyclidine Drugs 0.000 description 1
- 230000036470 plasma concentration Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000012207 quantitative assay Methods 0.000 description 1
- 238000012206 semi-quantitative assay Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 229940126585 therapeutic drug Drugs 0.000 description 1
- 238000010200 validation analysis Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/816—Alkaloids, amphetamines, and barbiturates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/901—Drugs of abuse, e.g. narcotics, amphetamine
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2006201307A AU2006201307A1 (en) | 2000-04-14 | 2006-03-29 | Device for detecting analytes related to sample pH |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09549725 | 2000-04-14 | ||
| US09/549,725 US6391261B1 (en) | 2000-04-14 | 2000-04-14 | Device for detecting analytes related to sample pH |
| PCT/US2001/011437 WO2001079838A1 (en) | 2000-04-14 | 2001-04-06 | Device for detecting analytes related to sample ph |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001251453A1 true AU2001251453A1 (en) | 2001-10-30 |
Family
ID=24194151
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001251453A Abandoned AU2001251453A1 (en) | 2000-04-14 | 2001-04-06 | Device for detecting analytes related to sample ph |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6391261B1 (ja) |
| EP (1) | EP1277052A4 (ja) |
| JP (1) | JP2003531375A (ja) |
| AU (1) | AU2001251453A1 (ja) |
| CA (1) | CA2404240A1 (ja) |
| NZ (1) | NZ521712A (ja) |
| WO (1) | WO2001079838A1 (ja) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040053417A1 (en) * | 2002-09-14 | 2004-03-18 | Sinsky Jerome L. | Diagnostic device and method of using same |
| US20040052684A1 (en) * | 2002-09-14 | 2004-03-18 | Sinsky Jerome L. | Diagnostic kit and method of using same |
| DE10309349B4 (de) * | 2003-03-03 | 2005-11-10 | Micronas Holding Gmbh | Vorrichtung zur Untersuchung eines Analyten |
| US7887750B2 (en) * | 2004-05-05 | 2011-02-15 | Bayer Healthcare Llc | Analytical systems, devices, and cartridges therefor |
| US20060133338A1 (en) * | 2004-11-23 | 2006-06-22 | Interdigital Technology Corporation | Method and system for securing wireless communications |
| US7993283B1 (en) * | 2007-07-23 | 2011-08-09 | Pop Test LLC | Method and apparatus for non-invasive analysis of saliva |
| JP5982920B2 (ja) * | 2012-03-22 | 2016-08-31 | 王子ホールディングス株式会社 | 吸収性物品 |
| JP5940861B2 (ja) * | 2012-03-30 | 2016-06-29 | アークレイ株式会社 | 唾液分泌促進用具 |
| JP6117499B2 (ja) * | 2012-08-23 | 2017-04-19 | 株式会社Kri | 唾液検査を用いた生活習慣病判定支援方法 |
| US20160018424A1 (en) * | 2013-03-01 | 2016-01-21 | Compassionate Analytic Inc. | Methods for cannabinoid quantification |
| EP2989461B1 (en) * | 2013-04-23 | 2019-03-06 | Cordant Research Solutions, LLC | Methods to determine body drug concentration from an oral fluid |
| WO2019169309A1 (en) * | 2018-03-02 | 2019-09-06 | Berger Russell Jay | Methods, apparatuses and kits for rapid testing of traumatic brain injuries |
| WO2024053464A1 (ja) * | 2022-09-06 | 2024-03-14 | 日東電工株式会社 | 分析システム、分析方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH065631Y2 (ja) * | 1987-03-05 | 1994-02-09 | ライオン株式会社 | 口腔用検査具 |
| US5069878A (en) * | 1987-03-24 | 1991-12-03 | Ehrenkranz Joel R L | Integrity preserving and determining urine sample collection apparatus |
| CA1303983C (en) | 1987-03-27 | 1992-06-23 | Robert W. Rosenstein | Solid phase assay |
| EP1248112A3 (en) | 1987-04-27 | 2004-08-25 | Inverness Medical Switzerland GmbH | Immunochromatographic specific binding assay device |
| US4943522A (en) | 1987-06-01 | 1990-07-24 | Quidel | Lateral flow, non-bibulous membrane assay protocols |
| JPH0199063U (ja) * | 1987-12-24 | 1989-07-03 | ||
| CA1331525C (en) * | 1988-05-19 | 1994-08-23 | Joel R. L. Ehrenkranz | Integrity preserving and determining urine sample collection apparatus |
| US5252496A (en) | 1989-12-18 | 1993-10-12 | Princeton Biomeditech Corporation | Carbon black immunochemical label |
| ES2089057T3 (es) * | 1990-07-18 | 1996-10-01 | Abbott Lab | Un reactivo sustituto de un analito para uso en metodos de ensayo de fijacion especifica, dispositivos y kits. |
| US5155022A (en) | 1991-02-08 | 1992-10-13 | Becton, Dickinson And Company | Assay for lyme disease |
| US5714341A (en) * | 1994-03-30 | 1998-02-03 | Epitope, Inc. | Saliva assay method and device |
| DE4444764A1 (de) * | 1994-12-16 | 1996-06-20 | Moell Claus Juergen | Testset zur Analyse von Körperflüssigkeiten, Verfahren zu seiner Herstellung und Analyseverfahren |
| US5726062A (en) * | 1995-04-19 | 1998-03-10 | Konica Corporation | Method of detecting protein and a kit detecting protein using the same |
| JPH095319A (ja) * | 1995-06-20 | 1997-01-10 | Showa Shell Sekiyu Kk | 尿中の被検出物質の検出方法およびそれに用いる検出用キット |
| JP3536268B2 (ja) * | 1995-10-09 | 2004-06-07 | アークレイ株式会社 | 多項目尿試験紙 |
| US5989840A (en) * | 1997-05-29 | 1999-11-23 | Americare International Diagnostics, Inc. | Estimation of active infection by heliobacter pylori |
| JP3786231B2 (ja) * | 1997-07-31 | 2006-06-14 | 久光製薬株式会社 | 検査用デバイス |
| US6102872A (en) * | 1997-11-03 | 2000-08-15 | Pacific Biometrics, Inc. | Glucose detector and method |
| JP2000009727A (ja) * | 1998-06-24 | 2000-01-14 | Daikin Ind Ltd | 唾液成分から血液成分への変換方法、その装置および診断装置 |
| US6022326A (en) * | 1998-10-30 | 2000-02-08 | Lifepoint, Inc. | Device and method for automatic collection of whole saliva |
-
2000
- 2000-04-14 US US09/549,725 patent/US6391261B1/en not_active Expired - Fee Related
-
2001
- 2001-04-06 EP EP01924835A patent/EP1277052A4/en not_active Withdrawn
- 2001-04-06 CA CA002404240A patent/CA2404240A1/en not_active Abandoned
- 2001-04-06 WO PCT/US2001/011437 patent/WO2001079838A1/en not_active Application Discontinuation
- 2001-04-06 AU AU2001251453A patent/AU2001251453A1/en not_active Abandoned
- 2001-04-06 JP JP2001576453A patent/JP2003531375A/ja active Pending
- 2001-04-06 NZ NZ521712A patent/NZ521712A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ521712A (en) | 2004-04-30 |
| JP2003531375A (ja) | 2003-10-21 |
| US6391261B1 (en) | 2002-05-21 |
| EP1277052A1 (en) | 2003-01-22 |
| WO2001079838A1 (en) | 2001-10-25 |
| CA2404240A1 (en) | 2001-10-25 |
| EP1277052A4 (en) | 2005-06-01 |
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