AU2000246280A1 - Tosylate salts of 4-(p-fluorophenyl)-piperidine-3-carbinols - Google Patents

Tosylate salts of 4-(p-fluorophenyl)-piperidine-3-carbinols

Info

Publication number
AU2000246280A1
AU2000246280A1 AU2000246280A AU4628000A AU2000246280A1 AU 2000246280 A1 AU2000246280 A1 AU 2000246280A1 AU 2000246280 A AU2000246280 A AU 2000246280A AU 4628000 A AU4628000 A AU 4628000A AU 2000246280 A1 AU2000246280 A1 AU 2000246280A1
Authority
AU
Australia
Prior art keywords
carbinols
fluorophenyl
piperidine
tosylate salts
tosylate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2000246280A
Other languages
English (en)
Inventor
Jacobus Maria Lemmens
Theodorus Hendricus Antonius Peters
Pavel Slanina
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthon BV
Original Assignee
Synthon BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthon BV filed Critical Synthon BV
Publication of AU2000246280A1 publication Critical patent/AU2000246280A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2000246280A 2000-05-12 2000-05-12 Tosylate salts of 4-(p-fluorophenyl)-piperidine-3-carbinols Abandoned AU2000246280A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/NL2000/000320 WO2001085688A1 (en) 2000-05-12 2000-05-12 TOSYLATE SALTS OF 4-(p-FLUOROPHENYL)-PIPERIDINE-3-CARBINOLS

Publications (1)

Publication Number Publication Date
AU2000246280A1 true AU2000246280A1 (en) 2001-11-20

Family

ID=19760688

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2000246280A Abandoned AU2000246280A1 (en) 2000-05-12 2000-05-12 Tosylate salts of 4-(p-fluorophenyl)-piperidine-3-carbinols

Country Status (6)

Country Link
US (1) US6521758B2 (cs)
EP (1) EP1280775A1 (cs)
AU (1) AU2000246280A1 (cs)
CZ (1) CZ20023694A3 (cs)
NL (1) NL1016012C1 (cs)
WO (1) WO2001085688A1 (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9930577D0 (en) * 1999-12-23 2000-02-16 Smithkline Beecham Plc Novel process
CN101205211B (zh) * 2006-12-19 2011-12-14 北京德众万全药物技术开发有限公司 一种盐酸帕罗西汀重要中间体的制备方法
EP2268639A2 (en) * 2008-05-22 2011-01-05 Teva Pharmaceutical Industries Ltd. Varenicline tosylate, an intermediate in the preparation process of varenicline l-tartrate
US8178537B2 (en) 2009-06-22 2012-05-15 Teva Pharmaceutical Industries Ltd. Solid state forms of varenicline salts and processes for preparation thereof
CN104402800A (zh) * 2014-12-02 2015-03-11 千辉药业（安徽）有限责任公司 一种反式-4-(4-氟苯基)-3-羟甲基-1-甲基哌啶的制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
US4585777A (en) 1984-02-07 1986-04-29 A/S Ferrosan (-)-Trans-4-(4-fluorophenyl)-3-(4-methoxyphenoxy)methylpiperidine for potentiating 5-HT
EP0190496A3 (en) * 1984-12-13 1987-05-27 Beecham Group Plc Piperidine derivatives having a gastro-intestinal activity
EP0223334B1 (en) * 1985-08-10 1991-07-10 Beecham Group Plc Process for the preparation of aryl-piperidine carbinols
GB8714707D0 (en) 1987-06-23 1987-07-29 Beecham Group Plc Chemical process
GB9209687D0 (en) 1992-05-06 1992-06-17 Smithkline Beecham Plc Novel process
US5258517A (en) 1992-08-06 1993-11-02 Sepracor, Inc. Method of preparing optically pure precursors of paroxetine
AU721257B2 (en) 1995-05-17 2000-06-29 Novo Nordisk A/S Process for preparing 4-aryl-piperidine derivatives
JP3446468B2 (ja) 1996-04-15 2003-09-16 旭硝子株式会社 ピペリジンカルビノール類の製造方法
JP3882224B2 (ja) 1996-05-31 2007-02-14 旭硝子株式会社 パロキセチンの製造方法
EP0812827B1 (en) 1996-06-13 2009-09-02 Sumitomo Chemical Company, Limited Piperidine derivative as intermediates for the preparation of paroxetine and process for their preparation
HU221921B1 (hu) 1996-07-08 2003-02-28 Richter Gedeon Vegyészeti Gyár Rt. N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására
GB9710004D0 (en) * 1997-05-17 1997-07-09 Knoll Ag Chemical process
DK0994872T3 (da) * 1997-06-10 2001-05-28 Synthon Bv 4-phenylpiperidin-forbindelser
WO2000026187A1 (en) * 1998-11-02 2000-05-11 Synthon B.V. Process for producing 4-arylpiperidine-3-carbinols and related compounds
PT1286965E (pt) * 2000-05-12 2004-04-30 Synthon Bv Compostos de piperidina e processo para a sua producao

Also Published As

Publication number Publication date
NL1016012C1 (nl) 2001-01-30
EP1280775A1 (en) 2003-02-05
US20020082277A1 (en) 2002-06-27
WO2001085688A1 (en) 2001-11-15
CZ20023694A3 (cs) 2003-05-14
US6521758B2 (en) 2003-02-18

Similar Documents

Publication Publication Date Title
AU2001263021A1 (en) Alkylamine derivatives of dihydropyridine npy antagonists
AU2002225855A1 (en) Preparation of nanocrystallites
AU2001262150A1 (en) 2-(nitrogen-heterocyclic)pyrimidone derivatives
AU2001255733A1 (en) Thiourea derivatives of dihydropyridine npy antagonists
AU2001257373A1 (en) Squarate derivatives of dihydropyridine npy antagonists
AU2002226486A1 (en) Novel c-glycoside derivatives and use thereof
AU2001234128A1 (en) Novel imidazoline compounds
AU2002226487A1 (en) Novel c-glycoside derivatives and use thereof
AU2001244634A1 (en) Diazepane derivatives or salts thereof
AU2002349777A1 (en) Novel benzophenone derivatives or salts thereof
AU2001252679A1 (en) Plaster
AU2002344107A1 (en) Alkyl ether derivatives or salts thereof
AU2002216314A1 (en) Heterocyclic angiogenesis inhibitors
AU2002234010A1 (en) Benzamidine derivatives
AU5248601A (en) Novel amorphous form of omeprazole salts
AU2001267852A1 (en) Novel pyrazinone derivatives
AU2001294824A1 (en) Piperazine based inhibitors of factor xa
AU2002217071A1 (en) Novel use of polyhydroxy compounds
AU2001266081A1 (en) Improvement of itraconazole bioavailability
AU2001258841A1 (en) Heterocyclic compounds
AU2000246280A1 (en) Tosylate salts of 4-(p-fluorophenyl)-piperidine-3-carbinols
AU1018801A (en) Use of 3,4-substituted piperidines
AU2002211281A1 (en) Quaternary amidino based inhibitors of factor xa
AU5029801A (en) Copolymers of allylphosphonium salts
NO20023785L (no) Vanndispergerbar formulering av paroxetin