AU2002216314A1 - Heterocyclic angiogenesis inhibitors - Google Patents

Heterocyclic angiogenesis inhibitors

Info

Publication number
AU2002216314A1
AU2002216314A1 AU2002216314A AU1631402A AU2002216314A1 AU 2002216314 A1 AU2002216314 A1 AU 2002216314A1 AU 2002216314 A AU2002216314 A AU 2002216314A AU 1631402 A AU1631402 A AU 1631402A AU 2002216314 A1 AU2002216314 A1 AU 2002216314A1
Authority
AU
Australia
Prior art keywords
angiogenesis inhibitors
heterocyclic
heterocyclic angiogenesis
inhibitors
angiogenesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002216314A
Inventor
Scott A Henderson
Barry R. Matthews
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU2002216314A1 publication Critical patent/AU2002216314A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/14—Thiadiazoles; Hydrogenated thiadiazoles condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2002216314A 2000-10-12 2001-10-12 Heterocyclic angiogenesis inhibitors Abandoned AU2002216314A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23927600P 2000-10-12 2000-10-12
US60/239,276 2000-10-12
PCT/IB2001/002722 WO2002030886A2 (en) 2000-10-12 2001-10-12 Heterocyclic angiogenesis inhibitors

Publications (1)

Publication Number Publication Date
AU2002216314A1 true AU2002216314A1 (en) 2002-04-22

Family

ID=22901433

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002216314A Abandoned AU2002216314A1 (en) 2000-10-12 2001-10-12 Heterocyclic angiogenesis inhibitors

Country Status (3)

Country Link
US (1) US20020128232A1 (en)
AU (1) AU2002216314A1 (en)
WO (1) WO2002030886A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003223930A1 (en) * 2002-06-14 2003-12-31 Novo Nordisk A/S Pharmaceutical use of boronic acids and esters thereof
MXPA06002017A (en) 2003-08-21 2006-05-31 Osi Pharm Inc N-substituted pyrazolyl-amidyl-benzimidazolyl c-kit inhibitors.
US7521448B2 (en) * 2003-08-21 2009-04-21 Osi Pharmaceuticals, Inc. N-substituted benzimidazolyl c-Kit inhibitors
US7442709B2 (en) 2003-08-21 2008-10-28 Osi Pharmaceuticals, Inc. N3-substituted imidazopyridine c-Kit inhibitors
EP1758891A2 (en) * 2004-06-15 2007-03-07 Pfizer Japan Inc. Benzimidazolone carboxylic acid derivatives
US7737163B2 (en) * 2004-06-15 2010-06-15 Pfizer Inc. Benzimidazolone carboxylic acid derivatives
KR20070086865A (en) * 2004-12-01 2007-08-27 오에스아이 파마슈티컬스, 인코포레이티드 N-substituted benzimidazolyl c-kit inhibitors and combinatorial benzimidazole library
JP4130220B1 (en) 2005-02-22 2008-08-06 ファイザー株式会社 Oxindole derivatives as 5HT4 receptor agonists
DE102006014685A1 (en) * 2006-03-28 2007-10-04 Sanofi-Aventis New bicyclic imidazolone derivatives useful as endothelial lipase inhibitors, e.g. for treating disorders of fat metabolism or glucose utilization
CN105399731A (en) * 2008-12-24 2016-03-16 比亚尔-珀特拉和Ca股份公司 Pharmaceutical Compounds
US8735406B2 (en) * 2009-09-09 2014-05-27 Dainippon Sumitomo Pharma Co., Ltd. 8-oxodihydropurine derivative
AU2018374469B2 (en) 2017-11-29 2022-06-16 F. Hoffmann-La Roche Ag Target interference suppressed anti-drug antibody assay
CN107915721A (en) * 2017-12-22 2018-04-17 田立志 A kind of sulfamide derivative and its application as Nampt inhibitor in antitumor drug
CN108042539A (en) * 2017-12-22 2018-05-18 田立志 A kind of sulfamide derivative, preparation method and its application in antitumor drug
CN108042538A (en) * 2017-12-22 2018-05-18 田立志 A kind of sulfamide derivative and its application as NAMPT inhibitor
CN107903246A (en) * 2017-12-22 2018-04-13 田立志 A kind of sulfamide derivative, preparation method and its it is antitumor in application
CN107954987A (en) * 2017-12-22 2018-04-24 田立志 A kind of sulfamide derivative and its application in antitumor drug
CN107987060A (en) * 2017-12-22 2018-05-04 田立志 A kind of sulfamide derivative and its application as NAMPT inhibitor in antitumor drug
CN107954988A (en) * 2017-12-22 2018-04-24 田立志 A kind of sulfamide derivative, preparation method and its application as NAMPT inhibitor in antitumor drug
AU2021294222A1 (en) 2020-06-16 2023-01-19 F. Hoffmann-La Roche Ag Method for determining the free antigen of an antibody in a sample

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3926982A (en) * 1974-07-03 1975-12-16 Squibb & Sons Inc Substituted benzimidazolinethiones
DD204258A1 (en) * 1981-12-28 1983-11-23 Adw Ddr PROCESS FOR THE PREPARATION OF BENZIMIDAZOLO / 1,2-D / (1,2,4) THIADIAZOLINENE
DD204259A1 (en) * 1981-12-28 1983-11-23 Adw Ddr PROCESS FOR THE PREPARATION OF BENZIMIDAZOLO / 2,1-B / (1,3,5) THIADIAZINES
AU5982298A (en) * 1997-03-07 1998-09-29 A/S Gea Farmaceutisk Fabrik Process for the preparation of 2-{{(2-pyridinyl)me thyl}sulfinyl}-1h-benzimidazoles and novel compounds of use for such purpos
AU1734401A (en) * 1999-12-09 2001-06-18 Mitsubishi Pharma Corporation Carboxyamido derivatives
US6506738B1 (en) * 2000-09-27 2003-01-14 Bristol-Myers Squibb Company Benzimidazolone antiviral agents

Also Published As

Publication number Publication date
US20020128232A1 (en) 2002-09-12
WO2002030886A2 (en) 2002-04-18
WO2002030886A3 (en) 2003-03-20

Similar Documents

Publication Publication Date Title
AU6623201A (en) Colchinol derivatives as angiogenesis inhibitors
IL153484A0 (en) Colchinol derivatives as angiogenesis inhibitors
AU2001258771A1 (en) -secretase inhibitors
AU2001237041A1 (en) Kinase inhibitors
SI1686119T1 (en) Pyrimidine-5-one derivatives as LDL-PLA2 inhibitors
AU4882101A (en) Mmp-12 inhibitors
AU2001244399A1 (en) Gamma-secretase inhibitors
AU2002250394A1 (en) Rho-kinase inhibitors
AU2002245709A1 (en) Rho-kinase inhibitors
AU2001296961A1 (en) 17-beta-hydroxysteroid dehydrogenase-ii inhibitors
AU2002216314A1 (en) Heterocyclic angiogenesis inhibitors
AU2001230537A1 (en) Pyridoxazine derivatives
AU2001285750A1 (en) Urokinase inhibitors
AU2002213978A1 (en) Substituted C-cyclohexylmethylamine derivatives
AU2002222627A1 (en) Tak1 inhibitors
AU2002232468A1 (en) Pharmaceutical heterocyclic compounds
AU2001258841A1 (en) Heterocyclic compounds
AU2001289937A1 (en) Substituted 1-aminobutan-3-ol derivatives
AU2002349621A1 (en) Angiogenesis inhibitor
AU3235100A (en) Prothease inhibitors
AU2001230565A1 (en) Perfluoroisopropylbenzene derivatives
AU1588901A (en) Protease inhibitors
AU1474801A (en) Protease inhibitors
AU2001255408A1 (en) Tetrahydro-azepinone derivatives as thrombin inhibitors
AU2001276354A1 (en) Hetaryl-substituted heterocycles