FR2815345B1
(en)
*
|
2000-10-12 |
2002-12-13 |
Servier Lab |
NOVEL CYCLOBUTENE-DIONE DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
|
CN1496254A
(en)
*
|
2000-12-15 |
2004-05-12 |
������ҩ������˾ |
Treatment of male sexual dysfunction
|
US20040132694A1
(en)
*
|
2001-01-16 |
2004-07-08 |
Palovich Michael R. |
Il-8 receptor antagonists
|
GB0121709D0
(en)
*
|
2001-09-07 |
2001-10-31 |
Imp College Innovations Ltd |
Food inhibition agent
|
EP2050460A1
(en)
*
|
2001-09-24 |
2009-04-22 |
Imperial Innovations Limited |
PYY and agonists thereof for modification of feeding behaviour
|
US8058233B2
(en)
*
|
2002-01-10 |
2011-11-15 |
Oregon Health And Science University |
Modification of feeding behavior using PYY and GLP-1
|
US7105526B2
(en)
|
2002-06-28 |
2006-09-12 |
Banyu Pharmaceuticals Co., Ltd. |
Benzimidazole derivatives
|
AR041834A1
(en)
*
|
2002-10-29 |
2005-06-01 |
Smithkline Beecham Corp |
COMPOSITE DIFENILUREA REPLACED WITH SULFONAMIDE, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT AND ITS USE TO PREPARE SUCH COMPOSITION
|
GB0300571D0
(en)
*
|
2003-01-10 |
2003-02-12 |
Imp College Innovations Ltd |
Modification of feeding behaviour
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
JP4765627B2
(en)
|
2003-09-22 |
2011-09-07 |
Msd株式会社 |
Novel piperidine derivatives
|
US20080125403A1
(en)
|
2004-04-02 |
2008-05-29 |
Merck & Co., Inc. |
Method of Treating Men with Metabolic and Anthropometric Disorders
|
ES2325773T5
(en)
|
2004-11-01 |
2014-02-24 |
Amylin Pharmaceuticals, Llc. |
Treatment of obesity and related disorders
|
WO2007022123A2
(en)
|
2005-08-11 |
2007-02-22 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides with selectable properties
|
US7737155B2
(en)
|
2005-05-17 |
2010-06-15 |
Schering Corporation |
Nitrogen-containing heterocyclic compounds and methods of use thereof
|
US8138206B2
(en)
|
2005-05-30 |
2012-03-20 |
Msd. K.K. |
Piperidine derivative
|
GB0511986D0
(en)
*
|
2005-06-13 |
2005-07-20 |
Imp College Innovations Ltd |
Novel compounds and their effects on feeding behaviour
|
CA2618112A1
(en)
|
2005-08-10 |
2007-02-15 |
Banyu Pharmaceutical Co., Ltd. |
Pyridone compound
|
EP2330125A3
(en)
|
2005-08-11 |
2012-12-12 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides with selectable properties
|
EP1921065B1
(en)
|
2005-08-24 |
2010-10-20 |
Banyu Pharmaceutical Co., Ltd. |
Phenylpyridone derivative
|
US20090264426A1
(en)
|
2005-09-07 |
2009-10-22 |
Shunji Sakuraba |
Bicyclic aromatic substituted pyridone derivative
|
CN101277960A
(en)
|
2005-09-29 |
2008-10-01 |
默克公司 |
Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
|
WO2007048027A2
(en)
|
2005-10-21 |
2007-04-26 |
Novartis Ag |
Combination of a renin-inhibitor and an anti-dyslipidemic agent and/or an antiobesity agent
|
AU2006307046A1
(en)
|
2005-10-27 |
2007-05-03 |
Msd K.K. |
Novel benzoxathiin derivative
|
JP4371164B2
(en)
|
2005-11-10 |
2009-11-25 |
萬有製薬株式会社 |
Aza-substituted spiro derivatives
|
CN101495113A
(en)
*
|
2006-04-21 |
2009-07-29 |
史密丝克莱恩比彻姆公司 |
IL-8 receptor antagonists
|
US20090093451A1
(en)
|
2006-04-21 |
2009-04-09 |
Smithkline Beecham Corporation |
IL-8 Receptor Antagonists
|
TW200817006A
(en)
*
|
2006-06-23 |
2008-04-16 |
Smithkline Beecham Corp |
IL-8 receptor antagonist
|
CA2664113C
(en)
|
2006-09-22 |
2013-05-28 |
Merck & Co., Inc. |
Use of platencin and platensimycin as fatty acid synthesis inhibitors to treat obesity, diabetes and cancer
|
EP2072519A4
(en)
|
2006-09-28 |
2009-10-21 |
Banyu Pharma Co Ltd |
Diaryl ketimine derivative
|
TWI428346B
(en)
*
|
2006-12-13 |
2014-03-01 |
Imp Innovations Ltd |
Novel compounds and their effects on feeding behaviour
|
US8106086B2
(en)
|
2007-04-02 |
2012-01-31 |
Msd K.K. |
Indoledione derivative
|
WO2008151257A2
(en)
|
2007-06-04 |
2008-12-11 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
US20110015181A1
(en)
|
2008-03-06 |
2011-01-20 |
Makoto Ando |
Alkylaminopyridine derivative
|
CN101981025A
(en)
|
2008-03-28 |
2011-02-23 |
万有制药株式会社 |
Diarylmethylamide derivative having antagonistic activity on melanin-concentrating hormone receptor
|
AU2009256157B2
(en)
|
2008-06-04 |
2014-12-18 |
Bausch Health Ireland Limited |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
AU2009261248A1
(en)
|
2008-06-19 |
2009-12-23 |
Banyu Pharmaceutical Co., Ltd. |
Spirodiamine-diarylketoxime derivative
|
EP2321341B1
(en)
|
2008-07-16 |
2017-02-22 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
|
WO2010013595A1
(en)
|
2008-07-30 |
2010-02-04 |
萬有製薬株式会社 |
(5-membered)-(5-membered) or (5-membered)-(6-membered) fused ring cycloalkylamine derivative
|
MX2011004258A
(en)
|
2008-10-22 |
2011-06-01 |
Merck Sharp & Dohme |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents.
|
PE20110852A1
(en)
|
2008-10-30 |
2011-11-25 |
Merck Sharp & Dohme |
ISONICOTINAMIDE OREXIN RECEPTOR ANTAGONISTS
|
EP2362731B1
(en)
|
2008-10-31 |
2016-04-06 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
WO2010075069A1
(en)
|
2008-12-16 |
2010-07-01 |
Schering Corporation |
Bicyclic pyranone derivatives as nicotinic acid receptor agonists
|
US20110245209A1
(en)
|
2008-12-16 |
2011-10-06 |
Schering Corporation |
Pyridopyrimidine derivatives and methods of use thereof
|
CA2786314A1
(en)
|
2010-02-25 |
2011-09-01 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
BR122021002201A8
(en)
|
2011-02-25 |
2023-04-11 |
Merck Sharp & Dohme |
COMPOUND, COMPOSITION, USE OF A COMPOUND, AND METHOD OF TREATMENT OF A DISORDER, CONDITION OR DISEASE
|
AR088352A1
(en)
|
2011-10-19 |
2014-05-28 |
Merck Sharp & Dohme |
ANTAGONISTS OF THE RECEIVER OF 2-PIRIDILOXI-4-NITRILE OREXINE
|
KR20150036245A
(en)
|
2012-08-02 |
2015-04-07 |
머크 샤프 앤드 돔 코포레이션 |
Antidiabetic tricyclic compounds
|
MX2015010935A
(en)
|
2013-02-22 |
2015-10-29 |
Merck Sharp & Dohme |
Antidiabetic bicyclic compounds.
|
US9650375B2
(en)
|
2013-03-14 |
2017-05-16 |
Merck Sharp & Dohme Corp. |
Indole derivatives useful as anti-diabetic agents
|
AU2014235209B2
(en)
|
2013-03-15 |
2018-06-14 |
Bausch Health Ireland Limited |
Guanylate cyclase receptor agonists combined with other drugs
|
WO2014151206A1
(en)
|
2013-03-15 |
2014-09-25 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase and their uses
|
WO2014197720A2
(en)
|
2013-06-05 |
2014-12-11 |
Synergy Pharmaceuticals, Inc. |
Ultra-pure agonists of guanylate cyclase c, method of making and using same
|
WO2015051496A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
MX2017002610A
(en)
|
2014-08-29 |
2017-10-11 |
Tes Pharma S R L |
INHIBITORS OF A-AMINO-ß-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE.
|
RU2019114228A
(en)
|
2016-10-14 |
2020-11-16 |
Тес Фарма С.Р.Л. |
Α-AMINO-β-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE INHIBITORS
|
EP3551176A4
(en)
|
2016-12-06 |
2020-06-24 |
Merck Sharp & Dohme Corp. |
Antidiabetic heterocyclic compounds
|
US10968232B2
(en)
|
2016-12-20 |
2021-04-06 |
Merck Sharp & Dohme Corp. |
Antidiabetic spirochroman compounds
|
AU2019385644A1
(en)
|
2018-11-20 |
2021-06-03 |
Tes Pharma S.R.L. |
Inhibitors of α-Amino-β-carboxymuconic acid semialdehyde decarboxylase
|
TW202045476A
(en)
|
2019-02-13 |
2020-12-16 |
美商默沙東藥廠 |
5-alkyl pyrrolidine orexin receptor agonists
|
WO2021026047A1
(en)
|
2019-08-08 |
2021-02-11 |
Merck Sharp & Dohme Corp. |
Heteroaryl pyrrolidine and piperidine orexin receptor agonists
|
KR20230053639A
(en)
|
2020-08-18 |
2023-04-21 |
머크 샤프 앤드 돔 엘엘씨 |
Bicycloheptane pyrrolidine orexin receptor agonists
|