ATE94755T1 - Pharmazeutische zusammensetzungen zum einatmen. - Google Patents

Pharmazeutische zusammensetzungen zum einatmen.

Info

Publication number
ATE94755T1
ATE94755T1 AT87901468T AT87901468T ATE94755T1 AT E94755 T1 ATE94755 T1 AT E94755T1 AT 87901468 T AT87901468 T AT 87901468T AT 87901468 T AT87901468 T AT 87901468T AT E94755 T1 ATE94755 T1 AT E94755T1
Authority
AT
Austria
Prior art keywords
inhalation
pharmaceutical compositions
microgranules
conglomerate
lubricant
Prior art date
Application number
AT87901468T
Other languages
English (en)
Inventor
Paolo Chiesi
Luciana Pavesi
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Application granted granted Critical
Publication of ATE94755T1 publication Critical patent/ATE94755T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT87901468T 1986-03-04 1987-02-27 Pharmazeutische zusammensetzungen zum einatmen. ATE94755T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT19625/86A IT1204826B (it) 1986-03-04 1986-03-04 Composizioni farmaceutiche per inalazione
PCT/EP1987/000118 WO1987005213A1 (en) 1986-03-04 1987-02-27 New pharmaceutical compositions for inhalation
EP87901468A EP0258356B1 (de) 1986-03-04 1987-02-27 Pharmazeutische zusammensetzungen zum einatmen

Publications (1)

Publication Number Publication Date
ATE94755T1 true ATE94755T1 (de) 1993-10-15

Family

ID=11159814

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87901468T ATE94755T1 (de) 1986-03-04 1987-02-27 Pharmazeutische zusammensetzungen zum einatmen.

Country Status (17)

Country Link
EP (2) EP0258356B1 (de)
JP (1) JPS63502895A (de)
KR (1) KR940000099B1 (de)
AT (1) ATE94755T1 (de)
AU (1) AU597964B2 (de)
CA (1) CA1297012C (de)
DE (2) DE3787502T2 (de)
ES (1) ES2031839T3 (de)
FI (1) FI90015C (de)
GR (2) GR880300017T1 (de)
HU (1) HU202748B (de)
IT (1) IT1204826B (de)
MY (1) MY102928A (de)
NO (1) NO874590L (de)
NZ (1) NZ219484A (de)
WO (1) WO1987005213A1 (de)
ZA (1) ZA871523B (de)

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JPH0558911A (ja) * 1991-08-27 1993-03-09 N D Shinyaku Kaihatsu Kenkyusho:Kk 鎮咳去痰剤
US5830853A (en) 1994-06-23 1998-11-03 Astra Aktiebolag Systemic administration of a therapeutic preparation
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
US6794357B1 (en) 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
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AUPM411494A0 (en) * 1994-02-25 1994-03-24 Central Sydney Area Health Service Method and device for the provocation of upper or lower airway narrowing and/or the induction of sputum
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DE4425255A1 (de) 1994-07-16 1996-01-18 Asta Medica Ag Formulierung zur inhalativen Applikation
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
SE9404468D0 (sv) * 1994-12-22 1994-12-22 Astra Ab Powder formulations
CN1088580C (zh) 1994-12-22 2002-08-07 阿斯特拉公司 气溶胶药物制剂
GB9501841D0 (en) * 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
GB9515182D0 (en) * 1995-07-24 1995-09-20 Co Ordinated Drug Dev Improvements in and relating to powders for use in dry powder inhalers
US6503537B2 (en) * 1997-03-20 2003-01-07 Schering Corporation Preparation of powder agglomerates
US6599883B1 (en) * 1998-10-30 2003-07-29 Nastech Pharmaceutical Company, Inc. Nasal delivery of xylitol
CA2347856C (en) * 1998-11-13 2009-02-17 Jagotec Ag Dry powder for inhalation
PL196951B1 (pl) 1999-03-05 2008-02-29 Chiesi Farma Spa Proszek do stosowania w inhalatorze suchego proszku, cząsteczki nośnika i sposób wytwarzania nośnika
ITMI991582A1 (it) 1999-07-16 2001-01-16 Chiesi Farma Spa Polveri costituite da particelle aventi la superficie perfettamente levigata da utilizzare come veicoli per la preparazione di miscele inala
PE20011227A1 (es) 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
GB0009469D0 (en) 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formalities for use in inhaler devices
IL153705A0 (en) 2000-06-27 2003-07-06 Vectura Ltd Method of making particles for use in a pharmaceutical composition
CA2413692C (en) * 2000-06-27 2011-10-18 Vectura Limited Method of making particles for use in a pharmaceutical composition
JP4380988B2 (ja) † 2000-11-30 2009-12-09 ヴェクトゥラ リミテッド 医薬組成物に用いられる粒子の製造方法
EP1337239B2 (de) 2000-11-30 2015-11-25 Vectura Limited Partikel zur verwendung in einer pharmazeutischen zusammensetzung
ES2587135T3 (es) 2000-11-30 2016-10-20 Vectura Limited Procedimiento de fabricación de partículas para su uso en una composición farmacéutica
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
DE10141377A1 (de) * 2001-08-23 2003-03-13 Boehringer Ingelheim Pharma Aufstreuverfahren zur Herstellung von Pulverformulierungen
DE10141376A1 (de) * 2001-08-23 2003-03-13 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Inhalationspulvern
US8337816B2 (en) 2001-09-17 2012-12-25 Glaxo Group Limited Dry powder medicament formulations
JP2005508220A (ja) * 2001-10-24 2005-03-31 パーリ・ゲーエムベーハー 薬用組成物調製用具
EP1417961A1 (de) * 2002-11-08 2004-05-12 Boehringer Ingelheim International GmbH Neue pharmazeutische Zubereitung enthaltend eine Kombination von Ambroxol oder Bromhexin und Isopropamid Jodid
JP2009513529A (ja) * 2003-07-11 2009-04-02 グラクソ グループ リミテッド ステアリン酸マグネシウムを含む医薬製剤
PE20050250A1 (es) 2003-07-17 2005-04-08 Glaxo Group Ltd Antagonistas de los receptores muscarinicos de la acetilcolina
DE602004030930D1 (de) 2003-10-14 2011-02-17 Glaxo Group Ltd Muscarinische acetylcholin-rezeptor-antagonisten
OA13270A (en) 2003-10-17 2007-01-31 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists.
TW200524577A (en) 2003-11-04 2005-08-01 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
GB0326632D0 (en) 2003-11-14 2003-12-17 Jagotec Ag Dry powder formulations
US7384946B2 (en) 2004-03-17 2008-06-10 Glaxo Group Limited M3 muscarinic acetylcholine receptor antagonists
AR050902A1 (es) 2004-04-27 2006-12-06 Glaxo Group Ltd Compuesto de quinuclidina, composicion farmaceutica que lo comprende y su usopara preparar dicha composicion
US7598267B2 (en) 2004-05-13 2009-10-06 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
US8524735B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
MX359219B (es) 2005-05-18 2018-09-19 Raptor Pharmaceuticals Inc Fluoroquinolonas aerosolizadas y sus usos.
EP1937068A4 (de) 2005-08-18 2010-08-04 Glaxo Group Ltd Antagonisten des muskarin acetylcholinrezeptors
GB0525254D0 (en) 2005-12-12 2006-01-18 Jagotec Ag Powder compositions for inhalation
US7832397B2 (en) 2005-12-28 2010-11-16 Philip Morris Usa Inc. Aerosol powder delivery device
GB0605723D0 (en) 2006-03-23 2006-05-03 3M Innovative Properties Co Powder filling processes
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PL3578169T3 (pl) 2009-02-26 2024-09-02 Glaxo Group Limited Preparaty farmaceutyczne zawierające 4-{(1r)-2-[(6-{2-[(2,6-dichlorobenzylo)oksy]etoksy}heksylo)amino]-1-hydroksyetylo}-2-(hydroksymetylo)fenol
SI2473170T1 (sl) 2009-09-04 2019-10-30 Horizon Orphan Llc Uporaba aerosoliziranega levofloksacina za zdravljenje cistične fibroze
GB0918249D0 (en) 2009-10-19 2009-12-02 Respivert Ltd Compounds
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
DK2560611T3 (en) * 2010-04-21 2018-02-26 Chiesi Farm Spa Process for providing particles with reduced electrostatic charges
TR201007250A2 (tr) 2010-09-01 2012-03-21 Bi̇lgi̇ç Mahmut Selobioz içeren formülasyon.
UY33337A (es) 2010-10-18 2011-10-31 Respivert Ltd DERIVADOS SUSTITUIDOS DE 1H-PIRAZOL[ 3,4-d]PIRIMIDINA COMO INHIBIDORES DE LAS FOSFOINOSITIDA 3-QUINASAS
CA2824432C (en) 2011-01-31 2021-10-19 Genoa Pharmaceuticals, Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
SI2834244T1 (sl) 2012-03-13 2016-12-30 Respivert Limited Inhibitorji kristalinične PI3 kinaze
EP2641900A1 (de) 2012-03-20 2013-09-25 Almirall, S.A. Neuartige polymorphe Kristallformen von 5-(2-{[6-(2,2-difluor-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxychinolin-2(1H)-on, Heminapadisylat als Agonist des beta2-adrenergen Rezeptors
EP2874928B1 (de) 2012-07-19 2016-06-15 Adamis Pharmaceuticals Corporation Pulverzufuhrvorrichtung
GB201305825D0 (en) * 2013-03-28 2013-05-15 Vectura Ltd New use
CA2919498C (en) 2013-07-31 2023-07-25 Windward Pharma, Inc. Aerosol nintedanib compounds and uses thereof
EP4491180A1 (de) 2014-01-10 2025-01-15 Avalyn Pharma Inc. Aerosol-pirfenidon- und pyridonanalogverbindungen und verwendungen davon
DE102016218604A1 (de) 2016-09-27 2018-03-29 Constantin Adams Partikuläres Stoffgemisch, vorzugsweise zur Verwendung bei der Prophylaxe und/oder Behandlung einer Atemwegsstörung
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung
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WO2023128916A1 (en) * 2021-12-31 2023-07-06 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi An apparatus with a grid (10) for the preparation of dry powder compositions for inhalation

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US3957965A (en) * 1967-08-08 1976-05-18 Fisons Limited Sodium chromoglycate inhalation medicament
DE3012136C2 (de) * 1980-03-28 1984-02-16 Bauer, Kurt Heinz, Prof. Dr., 7800 Freiburg Verfahren zur Herstellung eines Granulats

Also Published As

Publication number Publication date
EP0239798A1 (de) 1987-10-07
FI874710A0 (fi) 1987-10-26
EP0258356B1 (de) 1993-09-22
KR880700666A (ko) 1988-04-11
KR940000099B1 (ko) 1994-01-05
CA1297012C (en) 1992-03-10
FI874710L (fi) 1987-10-26
JPS63502895A (ja) 1988-10-27
WO1987005213A1 (en) 1987-09-11
HU202748B (en) 1991-04-29
DE3787502T2 (de) 1994-01-20
NO874590L (no) 1987-12-30
HUT46533A (en) 1988-11-28
FI90015B (fi) 1993-09-15
DE3787502D1 (de) 1993-10-28
NZ219484A (en) 1989-10-27
GR880300017T1 (en) 1988-10-18
EP0258356A1 (de) 1988-03-09
NO874590D0 (no) 1987-11-03
AU7164587A (en) 1987-09-28
IT1204826B (it) 1989-03-10
AU597964B2 (en) 1990-06-14
GR3000879T3 (en) 1991-11-15
MY102928A (en) 1993-03-31
FI90015C (fi) 1993-12-27
IT8619625A0 (it) 1986-03-04
DE258356T1 (de) 1988-09-01
ES2031839T3 (es) 1993-01-01
ZA871523B (en) 1987-08-24
EP0239798B1 (de) 1990-09-26

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee