ATE82499T1 - Okulare hypotensivagenzien. - Google Patents

Okulare hypotensivagenzien.

Info

Publication number
ATE82499T1
ATE82499T1 AT88308299T AT88308299T ATE82499T1 AT E82499 T1 ATE82499 T1 AT E82499T1 AT 88308299 T AT88308299 T AT 88308299T AT 88308299 T AT88308299 T AT 88308299T AT E82499 T1 ATE82499 T1 AT E82499T1
Authority
AT
Austria
Prior art keywords
hypotensive agents
ocular hypotensive
ocular
show
agents
Prior art date
Application number
AT88308299T
Other languages
English (en)
Inventor
Ryuzo Ueno
Ryuji Ueno
Tomio Oda
Original Assignee
R Tech Ueno Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26532381&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE82499(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by R Tech Ueno Ltd filed Critical R Tech Ueno Ltd
Application granted granted Critical
Publication of ATE82499T1 publication Critical patent/ATE82499T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT88308299T 1987-09-18 1988-09-08 Okulare hypotensivagenzien. ATE82499T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP23589087 1987-09-18
JP33403787 1987-12-29
EP88308299A EP0308135B1 (de) 1987-09-18 1988-09-08 Okulare Hypotensivagenzien

Publications (1)

Publication Number Publication Date
ATE82499T1 true ATE82499T1 (de) 1992-12-15

Family

ID=26532381

Family Applications (2)

Application Number Title Priority Date Filing Date
AT88308299T ATE82499T1 (de) 1987-09-18 1988-09-08 Okulare hypotensivagenzien.
AT91108317T ATE108330T1 (de) 1987-09-18 1988-09-08 Hypotensive okulare mittel.

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT91108317T ATE108330T1 (de) 1987-09-18 1988-09-08 Hypotensive okulare mittel.

Country Status (11)

Country Link
US (1) US5001153A (de)
EP (2) EP0308135B1 (de)
JP (2) JPH02108A (de)
KR (1) KR930000051B1 (de)
AT (2) ATE82499T1 (de)
CA (1) CA1328075C (de)
DE (2) DE3850676T2 (de)
ES (1) ES2052735T3 (de)
GB (1) GB2209939B (de)
GR (1) GR3006319T3 (de)
NZ (1) NZ226197A (de)

Families Citing this family (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1322749C (en) * 1987-01-28 1993-10-05 Ryuzo Ueno Prostaglandins of the d series, and tranquilizers and soporifics containing the same
US5236907A (en) * 1988-10-01 1993-08-17 R-Tech Ueno Ltd. Ocular hypotensive agents
US6420422B1 (en) 1987-09-18 2002-07-16 Sucampo Pharmaceuticals, Inc. Ocular hypotensive agents
JP2597629B2 (ja) 1988-02-26 1997-04-09 株式会社 上野製薬応用研究所 １３，１４−ジヒドロ−１５−ケトプロスタグランジン類の安定化
US6187813B1 (en) 1990-04-10 2001-02-13 Pharmacia & Upjohn Aktiebolag Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
US5296504A (en) * 1988-09-06 1994-03-22 Kabi Pharmacia Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
US5321128A (en) * 1988-09-06 1994-06-14 Kabi Pharmacia Ab Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
EP1300149A3 (de) * 1988-09-06 2003-05-14 Pharmacia Aktiebolag Prostaglandin-Derivate zur Behandlung von Glaukom oder Augenüberdruck
DE1300150T1 (de) * 1988-09-06 2003-09-18 Pharmacia Ab, Stockholm Prostaglandin-Derivate zur Behandlung von Glaukom oder Augenüberdruck
ATE111736T1 (de) * 1988-10-01 1994-10-15 R Tech Ueno Ltd Okulare hypotensive mittel.
US5194429A (en) * 1988-10-01 1993-03-16 K.K. Ueno Seiyaku Oyo Kenkyujo Ocular hypotensive agents
DE69019431T2 (de) * 1989-07-27 1995-09-14 Ueno Seiyaku Oyo Kenkyujo Kk Verwendung von 15-Keto-Prostansäure-Derivaten zur Herstellung eines Medikaments für die Verbesserung der Ausscheidung des Kaliumions.
US5234954A (en) * 1989-07-27 1993-08-10 K.K. Ueno Seiyaku Oyo Kenkyujo Treatment of hyperlipidemia with 15-keto-prostaglandin compounds
DE69018903T2 (de) * 1989-08-09 1995-08-24 Ueno Seiyaku Oyo Kenkyujo Kk Verwendung von Prostansäurederivaten zur Herstellung von Arzneimitteln zur Verbesserung der Ausscheidung von Nichtprotein in die Därme.
CA2027814C (en) * 1989-10-20 1996-07-30 Ryuji Ueno Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds
US5254588A (en) * 1989-11-22 1993-10-19 Kabushikikaisha Ueno Seiyaku Oyo Kenkyujo Treatment of pulmonary dysfunction with 15-ketoprostaglandin compounds
CA2030345C (en) * 1989-11-22 1998-12-08 Ryuji Ueno Use of 15-keto-prostaglandin compound for improvement of encephalic function
US5256696A (en) * 1989-11-22 1993-10-26 Kabushikikaisha Ueno Seiyaku Oyo Kenkyujo Treatment of cardiac dysfunction with 15-ketoprostaglandin compounds
EP0471856B1 (de) * 1990-03-08 1995-03-22 Shionogi & Co., Ltd. 15-deoxyprostaglandinderivat
TW249226B (de) * 1990-04-04 1995-06-11 Aderk Ueno Kk
CA2041417C (en) * 1990-05-01 2002-05-21 Ryuji Ueno Treatment of pancreatic disease with 15-keto-prostaglandin compounds
ES2059058T3 (es) * 1990-05-22 1994-11-01 R Tech Ueno Ltd Combinacion sinergica para uso oftalmico.
EP0458590B1 (de) * 1990-05-22 1996-01-10 R-Tech Ueno Ltd. Behandlung von intraokularem Druck mit einer synergischen Kombination
CA2042934C (en) * 1990-05-22 2002-04-23 Ryuji Ueno Treatment of ocular hypertension with an ocular synergistic combination
ES2067864T3 (es) * 1990-05-22 1995-04-01 R Tech Ueno Ltd Tratamiento de la hipertension ocular con una combinacion sinergica para administracion ocular.
US5175189A (en) * 1990-05-22 1992-12-29 K.K. Ueno Seiyaku Oyo Kenkyujo Treatment of ocular hypertension with a synergistic combination for ophthalmic use
CA2046069C (en) * 1990-07-10 2002-04-09 Ryuji Ueno Treatment of inflammatory diseases with 15-keto-prostaglandin compounds
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US5139491A (en) * 1990-12-06 1992-08-18 Allergan, Inc. 2-decarboxyl-2-alkoxyalkyl prostaglandins as ocular hypotensives
TW210287B (de) * 1991-03-01 1993-08-01 Kabushikaisha Ueno Seiyaku Oyo Kenkyujo
DK0503887T3 (da) * 1991-03-14 1996-09-16 R Tech Ueno Ltd Fremme af sårheling med 15-ketoprostaglandinforbindelser
CA2065889C (en) * 1991-10-02 2002-08-27 Tetsuya Sugiyama Increasing the choroidal blood flow
EP0668076B1 (de) * 1992-08-26 2002-09-04 Sucampo AG Stabilisierung von Prostansäurederivaten
FR2707295A1 (fr) * 1993-06-07 1995-01-13 Rhone Poulenc Agrochimie Fongicides pyrazoles substitués en position 3 par un hétérocycle.
US6184250B1 (en) 1993-08-03 2001-02-06 Alcon Laboratories, Inc. Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
US5510383A (en) * 1993-08-03 1996-04-23 Alcon Laboratories, Inc. Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension
US5387608A (en) * 1993-08-17 1995-02-07 Allergan, Inc. Cyclopentane(ene) heptanoic or cyclopentane(ene) heptenoic acid, 2-hydrocarbyl sulfonamidomethyl and derivatives thereof as therapeutic agents
CA2138181A1 (en) * 1993-12-15 1995-06-16 Verney L. Sallee Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension
US5807892A (en) * 1994-09-30 1998-09-15 Alcon Laboratories, Inc. Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension
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ATE202557T1 (de) * 1996-11-12 2001-07-15 Alcon Lab Inc 15-fluoro-prostaglandine als augendrucksenkende mittel
AU750039B2 (en) 1997-02-04 2002-07-11 Murray A. Johnstone Method of enhancing hair growth
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ATE326972T1 (de) 1997-10-13 2006-06-15 R Tech Ueno Ltd Heilende zusammensetzung für intraokulare hypertension oder glaukom
US6156785A (en) * 1998-01-23 2000-12-05 Merck Sharp & Dohme B.V. Method for increasing oxygen tension in the optic nerve and retina
US6096783A (en) * 1998-12-15 2000-08-01 Alcon Laboratories, Inc. Cyclobutane prostaglandin analogues as ocular hypotensive agents
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SE9900672D0 (sv) 1999-02-25 1999-02-25 Synphora Ab Method and composition for prevention of scar formation in glaucoma filtration bleb and drainage fistula
ES2232434T3 (es) 1999-03-05 2005-06-01 Duke University Analogos de prostaglandinas c-16 fp selectivas insaturadas.
TWI225398B (en) 1999-07-14 2004-12-21 R Tech Ueno Ltd Composition for treatment of external secretion disorders
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US6548535B2 (en) * 2000-01-18 2003-04-15 Merck & Co., Inc. Method for treating ocular hypertension
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US6458836B1 (en) 2000-03-16 2002-10-01 Sucampo, A.G. Treatment of ocular hypertension and glaucoma
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US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020013294A1 (en) * 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
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US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
PE20020146A1 (es) * 2000-07-13 2002-03-31 Upjohn Co Formulacion oftalmica que comprende un inhibidor de ciclooxigenasa-2 (cox-2)
US20020035148A1 (en) * 2000-07-20 2002-03-21 Ryuji Ueno Treatment of ocular hypertension
US6414021B1 (en) * 2000-08-25 2002-07-02 Sucampo Ag Control of intraocular pressure during surgery
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US6291522B1 (en) * 2000-09-27 2001-09-18 Allergan Sales, Inc. Cyclopentane heptan(ENE)oic acid, 2-thiocarbamoyloxy and 2-carbamoyloxy compounds as therapeutic agents
US20040254230A1 (en) * 2001-12-03 2004-12-16 Ogidigben Miller J. Method for treating ocular hypertension
US7351404B2 (en) * 2002-02-04 2008-04-01 Allergan, Inc. Method of enhancing hair growth
US8758733B2 (en) 2002-02-04 2014-06-24 Allergan, Inc. Topical treatment for chemotherapy induced eyelash loss or hypotrichosis using prostamide F2 alpha agonists
US9216183B2 (en) 2002-02-04 2015-12-22 Allergan, Inc. Topical treatment for chemotherapy induced eyelash loss or hypotrichosis using prostamide F2 alpha agonists
EP1487438A4 (de) * 2002-03-15 2007-08-15 Merck & Co Inc Zusammensetzungen und verfahren zur behandlung von glaukom und okularer hypertonie
AU2003233731A1 (en) * 2002-06-06 2003-12-22 Xavier Billot 1,5-disubstituted imidazolidin-2-one derivatives for use as ep4 receptor agonists in the treatment of eye and bone diseases
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KR101092048B1 (ko) * 2002-08-29 2011-12-12 산텐 세이야꾸 가부시키가이샤 Ｒｈｏ 키나아제 억제제 및 프로스타글란딘류를 포함하는녹내장 치료제
WO2004037786A2 (en) * 2002-10-25 2004-05-06 Merck Frosst Canada & Co. 2-pyrrolidones as ep4 receptor agonists
EP1568382B1 (de) 2002-11-18 2013-11-06 Santen Pharmaceutical Co., Ltd. HEILMITTEL FÜR GRÜNEN STAR, UMFASSEND Rho-KINASE UND beta-BLOCKER
CA2519899A1 (en) * 2003-03-27 2004-10-14 Merck & Co., Inc. Ophthalmic compositions for treating ocular hypertension
EP1666043B1 (de) * 2003-07-31 2009-12-02 Santen Pharmaceutical Co., Ltd. Prostaglandin enthaltendes produkt
TWI348386B (en) * 2003-08-12 2011-09-11 R Tech Ueno Ltd Composition and method for promoting hair growth
KR101091461B1 (ko) 2003-11-07 2011-12-07 센주 세이야꾸 가부시키가이샤 프로스타글란딘 함유 의약 조성물
WO2006062184A1 (ja) * 2004-12-09 2006-06-15 Santen Pharmaceutical Co., Ltd. 分子内にフッ素原子を有するプロスタグランジン含有製品
PL1829545T3 (pl) * 2004-12-24 2012-09-28 Santen Pharmaceutical Co Ltd Produkty zawierające pochodną prostaglandyny F2 alfa
WO2006070942A1 (en) * 2004-12-29 2006-07-06 R-Tech Ueno, Ltd Composition and method for scalp and hair treatment
AR055038A1 (es) * 2005-03-04 2007-08-01 Sucampo Ag Metodo y compuesto para tratar enfermedades vasculares perifericas
JP4648340B2 (ja) * 2006-02-07 2011-03-09 株式会社アールテック・ウエノ １５−ケトプロスタグランジンｅ誘導体の製造法
BRPI0708891A2 (pt) * 2006-03-13 2011-06-28 R Tech Ueno Ltd composição aquosa
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US20100204335A1 (en) * 2008-12-01 2010-08-12 Allergan, Inc. Kit and composition for eyelash growth
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TW202446398A (zh) 2011-02-04 2024-12-01 日商興和股份有限公司 具眼壓下降作用之醫藥
JP2014510022A (ja) 2011-04-07 2014-04-24 スキャンポ・アーゲー 眼精疲労の処置方法
BR112014002712A8 (pt) * 2011-08-05 2017-06-20 Sucampo Ag método para tratamento da esquizofrenia
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Family Cites Families (10)

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GB1476661A (en) * 1974-05-13 1977-06-16 American Cyanamid Co Prostaglandins
US4599353A (en) * 1982-05-03 1986-07-08 The Trustees Of Columbia University In The City Of New York Use of eicosanoids and their derivatives for treatment of ocular hypertension and glaucoma
JPH0643313B2 (ja) * 1986-03-13 1994-06-08 ザ・トラステイ−ズ・オブ・コロンビア・ユニヴア−シテイ・イン・ザ・シテイ・オブ・ニユ−・ヨ−ク 緑内障の局所治療用組成物
US4824857A (en) * 1986-05-16 1989-04-25 Yasumasa Goh Use of prostaglandin D2 -active substances
CA1323364C (en) * 1987-01-28 1993-10-19 Ryuzo Ueno Prostaglandins e and anti ulcer agents containing same
CA1322749C (en) * 1987-01-28 1993-10-05 Ryuzo Ueno Prostaglandins of the d series, and tranquilizers and soporifics containing the same
CA1324129C (en) * 1987-04-30 1993-11-09 Ryuzo Ueno Prostaglandins of the f series
EP0292177B1 (de) * 1987-05-15 1992-03-25 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Fiebersteigende Zusammensetzung
JPS6453101A (en) * 1987-05-25 1989-03-01 Kurashiki Boseki Kk Equal tilt angle interference type film thickness gauge
JP2597629B2 (ja) * 1988-02-26 1997-04-09 株式会社 上野製薬応用研究所 １３，１４−ジヒドロ−１５−ケトプロスタグランジン類の安定化

Also Published As

Publication number Publication date
GB8821104D0 (en) 1988-10-05
EP0308135A3 (en) 1989-06-14
AU2231388A (en) 1989-03-23
ATE108330T1 (de) 1994-07-15
DE3850676D1 (de) 1994-08-18
JPH02108A (ja) 1990-01-05
JPH0680571A (ja) 1994-03-22
NZ226197A (en) 1992-02-25
JPH0571567B2 (de) 1993-10-07
CA1328075C (en) 1994-03-29
DE3876050D1 (de) 1992-12-24
EP0455264B1 (de) 1994-07-13
EP0308135A2 (de) 1989-03-22
KR890004707A (ko) 1989-05-09
EP0455264A2 (de) 1991-11-06
ES2052735T3 (es) 1994-07-16
JP2592204B2 (ja) 1997-03-19
DE3876050T2 (de) 1993-03-25
KR930000051B1 (ko) 1993-01-06
GR3006319T3 (de) 1993-06-21
EP0308135B1 (de) 1992-11-19
GB2209939A (en) 1989-06-01
DE3850676T2 (de) 1994-11-03
AU600168B2 (en) 1990-08-02
GB2209939B (en) 1992-01-02
US5001153A (en) 1991-03-19
EP0455264A3 (en) 1991-11-27

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