ATE546136T1 - Kardioprotektions- und neuroprotektionsverfahren durch intravenöse verabreichung von halogenierten flüchtigen narkosemitteln - Google Patents
Kardioprotektions- und neuroprotektionsverfahren durch intravenöse verabreichung von halogenierten flüchtigen narkosemittelnInfo
- Publication number
- ATE546136T1 ATE546136T1 AT03774657T AT03774657T ATE546136T1 AT E546136 T1 ATE546136 T1 AT E546136T1 AT 03774657 T AT03774657 T AT 03774657T AT 03774657 T AT03774657 T AT 03774657T AT E546136 T1 ATE546136 T1 AT E546136T1
- Authority
- AT
- Austria
- Prior art keywords
- cardioprotection
- neuroprotection
- procedures
- intravenous administration
- volatile anesthetic
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 239000003983 inhalation anesthetic agent Substances 0.000 title abstract 2
- 230000005961 cardioprotection Effects 0.000 title 1
- 238000001990 intravenous administration Methods 0.000 title 1
- 230000004112 neuroprotection Effects 0.000 title 1
- 230000000302 ischemic effect Effects 0.000 abstract 4
- 238000009472 formulation Methods 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 230000002107 myocardial effect Effects 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/02—Halogenated hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Ophthalmology & Optometry (AREA)
- Psychiatry (AREA)
- Gastroenterology & Hepatology (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41793402P | 2002-10-11 | 2002-10-11 | |
| PCT/US2003/031826 WO2004032858A2 (en) | 2002-10-11 | 2003-10-09 | Method for cardioprotection and neuroprotection by intravenous administration of halogenated volatile anesthetics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE546136T1 true ATE546136T1 (de) | 2012-03-15 |
Family
ID=32094122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03774657T ATE546136T1 (de) | 2002-10-11 | 2003-10-09 | Kardioprotektions- und neuroprotektionsverfahren durch intravenöse verabreichung von halogenierten flüchtigen narkosemitteln |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7999011B2 (enExample) |
| EP (1) | EP1558226B1 (enExample) |
| JP (1) | JP5210486B2 (enExample) |
| KR (2) | KR101403264B1 (enExample) |
| CN (2) | CN1703209A (enExample) |
| AT (1) | ATE546136T1 (enExample) |
| AU (1) | AU2003282464B2 (enExample) |
| BR (1) | BR0314617A (enExample) |
| CA (1) | CA2500310C (enExample) |
| DK (1) | DK1558226T3 (enExample) |
| ES (1) | ES2382911T3 (enExample) |
| HK (1) | HK1079703A1 (enExample) |
| IL (1) | IL167472A (enExample) |
| MX (1) | MXPA05003741A (enExample) |
| NZ (1) | NZ539298A (enExample) |
| PL (1) | PL219493B1 (enExample) |
| RU (1) | RU2350323C2 (enExample) |
| WO (1) | WO2004032858A2 (enExample) |
| ZA (1) | ZA200502741B (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003026611A2 (en) | 2001-09-26 | 2003-04-03 | Baxter International Inc. | Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal |
| US7449616B2 (en) | 2002-12-24 | 2008-11-11 | Pfizer Inc. | Anti-NGF antibodies and methods using same |
| ES2573253T3 (es) * | 2006-09-20 | 2016-06-06 | The Board Of Regents Of The University Of Texas System | Métodos para el suministro de anestésicos volátiles para anestesia regional y/o alivio del dolor |
| GB0619499D0 (en) | 2006-10-03 | 2006-11-08 | Lucent Technologies Inc | Encrypted data in a wireless telecommunications system |
| DE112008002914A5 (de) * | 2007-11-06 | 2010-09-30 | B. Braun Melsungen Ag | Einen hydrophoben Wirkstoff enthaltende wässrige Emulsionen |
| CN107661293A (zh) * | 2008-01-22 | 2018-02-06 | 得克萨斯大学体系董事会 | 用于局部麻醉和/或疼痛缓解的含有萃取溶剂的挥发性麻醉剂组合物 |
| AU2015200210B2 (en) * | 2008-01-22 | 2016-08-11 | The Board Of Regents Of The University Of Texas System | Volatile anesthetic compositions comprising extractive solvents for regional anesthesia and/or pain relief |
| US20110159078A1 (en) * | 2008-01-22 | 2011-06-30 | Vapogenix, Inc | Volatile Anesthetic Compositions and Methods of Use |
| AU2010245932B2 (en) * | 2009-05-05 | 2015-08-06 | Board Of Regents, The University Of Texas System | Novel formulations of volatile anesthetics and methods of use for reducing inflammation |
| RU2408396C1 (ru) * | 2009-07-30 | 2011-01-10 | Государственное образовательное учреждение высшего профессионального образования "Тверская государственная медицинская академия Федерального агентства по здравоохранению и федеральному развитию" | Комбинированная двухсегментарная регионарная анестезия при выполнении каротидной эндартерэктомии у больных критической ишемией нижних конечностей и выраженным болевым синдромом |
| US20120219596A1 (en) | 2009-07-30 | 2012-08-30 | Wendelin Stark | Injectable formulation for treatment and protection of patients having an inflammatory reaction or an ischemia-reperfusion event |
| FR2956323B1 (fr) * | 2010-02-15 | 2013-12-20 | Air Liquide | Medicament gazeux inhalable a base d'argon contre les deficiences ou defaillances d'organes peripheriques |
| JP2014520157A (ja) | 2011-06-24 | 2014-08-21 | ベイポジェニックス インコーポレイテッド | 皮膚科障害または皮膚科疾患を処置するための新規製剤および方法 |
| EP3854389A1 (en) * | 2013-03-15 | 2021-07-28 | Vapogenix, Inc. | Novel analgesic compositions |
| ITMO20130075A1 (it) * | 2013-03-22 | 2014-09-23 | Enrico Giuliani | Dispositivo di somministrazione |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1018773A (en) * | 1962-09-13 | 1966-02-02 | Bellon Labor Sa Roger | ª‡-phenyl-ª‰-2-furyl-propionitrile derivatives |
| US4073943A (en) | 1974-09-11 | 1978-02-14 | Apoteksvarucentralen Vitrum Ab | Method of enhancing the administration of pharmalogically active agents |
| US5628930A (en) | 1992-10-27 | 1997-05-13 | Alliance Pharmaceutical Corp. | Stabilization of fluorocarbon emulsions |
| US5635538A (en) | 1993-03-16 | 1997-06-03 | Alliance Pharmaceutical Corp. | Fluorocarbon emulsions with reduced pulmonary gas-trapping properties |
| JP2961034B2 (ja) * | 1993-09-16 | 1999-10-12 | アルプス電気株式会社 | 磁気ヘッド |
| DE69429524T2 (de) | 1993-09-24 | 2002-08-08 | The University Of British Columbia, Vancouver | Aminocyclohexylester und ihre anwendung |
| FR2726267B1 (fr) * | 1994-10-26 | 1998-01-02 | Smithkline Beecham Lab | Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer |
| GB2350297A (en) * | 1999-05-27 | 2000-11-29 | Abbott Lab | Injectable halogenated anesthetic formulation in emulsion form |
| CA2416535C (en) * | 2000-07-26 | 2010-11-16 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbiturate compounds as neuroprotective agents |
-
2003
- 2003-10-09 HK HK05112083.8A patent/HK1079703A1/zh unknown
- 2003-10-09 MX MXPA05003741A patent/MXPA05003741A/es active IP Right Grant
- 2003-10-09 BR BR0314617-0A patent/BR0314617A/pt not_active Application Discontinuation
- 2003-10-09 AU AU2003282464A patent/AU2003282464B2/en not_active Ceased
- 2003-10-09 JP JP2004543499A patent/JP5210486B2/ja not_active Expired - Lifetime
- 2003-10-09 ES ES03774657T patent/ES2382911T3/es not_active Expired - Lifetime
- 2003-10-09 EP EP03774657A patent/EP1558226B1/en not_active Expired - Lifetime
- 2003-10-09 AT AT03774657T patent/ATE546136T1/de active
- 2003-10-09 WO PCT/US2003/031826 patent/WO2004032858A2/en not_active Ceased
- 2003-10-09 NZ NZ539298A patent/NZ539298A/en not_active IP Right Cessation
- 2003-10-09 DK DK03774657.5T patent/DK1558226T3/da active
- 2003-10-09 US US10/682,303 patent/US7999011B2/en active Active
- 2003-10-09 KR KR1020057006049A patent/KR101403264B1/ko not_active Expired - Fee Related
- 2003-10-09 CN CNA2003801012256A patent/CN1703209A/zh active Pending
- 2003-10-09 CA CA2500310A patent/CA2500310C/en not_active Expired - Fee Related
- 2003-10-09 PL PL376217A patent/PL219493B1/pl unknown
- 2003-10-09 KR KR1020127005009A patent/KR20120030598A/ko not_active Ceased
- 2003-10-09 CN CN2011101820964A patent/CN102283821A/zh active Pending
- 2003-10-09 RU RU2005114008/14A patent/RU2350323C2/ru not_active IP Right Cessation
-
2005
- 2005-03-16 IL IL167472A patent/IL167472A/en active IP Right Grant
- 2005-04-05 ZA ZA200502741A patent/ZA200502741B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003282464B2 (en) | 2010-02-25 |
| PL219493B1 (pl) | 2015-05-29 |
| CA2500310A1 (en) | 2004-04-22 |
| AU2003282464A1 (en) | 2004-05-04 |
| HK1079703A1 (zh) | 2006-04-13 |
| RU2005114008A (ru) | 2005-10-27 |
| US20040127578A1 (en) | 2004-07-01 |
| NZ539298A (en) | 2008-11-28 |
| KR20050056230A (ko) | 2005-06-14 |
| WO2004032858A3 (en) | 2004-09-23 |
| EP1558226A4 (en) | 2008-04-02 |
| IL167472A (en) | 2013-10-31 |
| KR20120030598A (ko) | 2012-03-28 |
| KR101403264B1 (ko) | 2014-06-02 |
| CN1703209A (zh) | 2005-11-30 |
| CA2500310C (en) | 2013-03-12 |
| US7999011B2 (en) | 2011-08-16 |
| JP5210486B2 (ja) | 2013-06-12 |
| ES2382911T3 (es) | 2012-06-14 |
| RU2350323C2 (ru) | 2009-03-27 |
| DK1558226T3 (da) | 2012-05-07 |
| EP1558226A2 (en) | 2005-08-03 |
| ZA200502741B (en) | 2006-02-22 |
| EP1558226B1 (en) | 2012-02-22 |
| CN102283821A (zh) | 2011-12-21 |
| BR0314617A (pt) | 2005-08-02 |
| MXPA05003741A (es) | 2005-06-17 |
| JP2006504740A (ja) | 2006-02-09 |
| PL376217A1 (en) | 2005-12-27 |
| WO2004032858A2 (en) | 2004-04-22 |
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