ATE533748T1 - Enantioselektive alkylierung von trizyklischen verbindungen - Google Patents

Enantioselektive alkylierung von trizyklischen verbindungen

Info

Publication number
ATE533748T1
ATE533748T1 AT10001106T AT10001106T ATE533748T1 AT E533748 T1 ATE533748 T1 AT E533748T1 AT 10001106 T AT10001106 T AT 10001106T AT 10001106 T AT10001106 T AT 10001106T AT E533748 T1 ATE533748 T1 AT E533748T1
Authority
AT
Austria
Prior art keywords
tricyclic compounds
enantioselective alkylation
enantioselective
alkylation
tricyclic
Prior art date
Application number
AT10001106T
Other languages
English (en)
Inventor
Frank X Chen
Yee-Shing Wong
Jeffrey M Eckert
Nanfei Zou
Feng Liang
Agnes S Kim-Meade
Marc Poirier
Tiruvettipuram K Thiruvengadam
George G Wu
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE533748T1 publication Critical patent/ATE533748T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/16Ring systems of three rings containing carbocyclic rings other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT10001106T 2002-10-03 2003-10-01 Enantioselektive alkylierung von trizyklischen verbindungen ATE533748T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41567302P 2002-10-03 2002-10-03
US41880602P 2002-10-15 2002-10-15

Publications (1)

Publication Number Publication Date
ATE533748T1 true ATE533748T1 (de) 2011-12-15

Family

ID=32073383

Family Applications (3)

Application Number Title Priority Date Filing Date
AT10001106T ATE533748T1 (de) 2002-10-03 2003-10-01 Enantioselektive alkylierung von trizyklischen verbindungen
AT03799375T ATE365157T1 (de) 2002-10-03 2003-10-01 Enantioselective alkylierung von trizyklischen verbindungen
AT07002950T ATE461921T1 (de) 2002-10-03 2003-10-01 Enantioselektive alkylierung von trizyklischen verbindungen

Family Applications After (2)

Application Number Title Priority Date Filing Date
AT03799375T ATE365157T1 (de) 2002-10-03 2003-10-01 Enantioselective alkylierung von trizyklischen verbindungen
AT07002950T ATE461921T1 (de) 2002-10-03 2003-10-01 Enantioselektive alkylierung von trizyklischen verbindungen

Country Status (17)

Country Link
US (2) US7049440B2 (de)
EP (3) EP1780203B1 (de)
JP (2) JP4679150B2 (de)
CN (2) CN101289425B (de)
AR (1) AR041466A1 (de)
AT (3) ATE533748T1 (de)
AU (1) AU2003277194A1 (de)
CA (1) CA2501292A1 (de)
CY (1) CY1107481T1 (de)
DE (2) DE60314535T2 (de)
DK (1) DK1556358T3 (de)
ES (3) ES2285252T3 (de)
MX (1) MXPA05003518A (de)
PT (1) PT1556358E (de)
SI (1) SI1556358T1 (de)
WO (1) WO2004031153A2 (de)
ZA (1) ZA200502581B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060205810A1 (en) * 2004-11-24 2006-09-14 Schering Corporation Platinum therapeutic combinations
US8784618B2 (en) 2010-08-19 2014-07-22 International Business Machines Corporation Working electrode design for electrochemical processing of electronic components
CN107021925B (zh) * 2017-05-23 2020-05-29 中节能万润股份有限公司 一种以氮杂二苯并环庚酮为核心的化合物及其在oled上的应用
EP3741743A4 (de) * 2018-01-19 2021-10-20 Yuki Gosei Kogyo Co., Ltd. Verfahren zur herstellung von 1-(1-tert-butoxycarbonyl-4-piperidylacetyl)-4-mesyloxypiperidin und 1-(1-tert-butoxycarbonyl-4-piperidylacetyl)-4-mesyloxypiperidin
CN111868031B (zh) * 2018-01-19 2023-10-03 有机合成药品工业株式会社 N-烷氧基羰基哌啶衍生物的制备方法及其中间体

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5264577A (en) 1992-04-22 1993-11-23 Warner-Lambert Company Cyclic amino acids and derivatives thereof
US5719148A (en) 1993-10-15 1998-02-17 Schering Corporation Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
US5874442A (en) 1995-12-22 1999-02-23 Schering-Plough Corporation Tricyclic amides useful for inhibition of G-protein function and for treatment of proliferative disease
MY119007A (en) * 1995-12-22 2005-03-31 Schering Corp Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases.
KR20000036111A (ko) * 1996-09-13 2000-06-26 둘락 노먼 씨. 파네실 단백질 트랜스페라제 억제제인 트리사이클릭 항종양성화합물
US5962741A (en) * 1996-11-19 1999-10-05 Novartis Ag Process for the production of aromatic halogen-amino compounds
US5998620A (en) 1997-03-25 1999-12-07 Schering Corporation Synthesis of intermediates useful in preparing tricyclic compounds
US5760232A (en) 1997-06-16 1998-06-02 Schering Corporation Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds
US6426352B1 (en) * 1997-06-17 2002-07-30 Schering Corporation Sulfonamide inhibitors of farnesyl-protein transferase
US6576639B1 (en) * 1997-06-17 2003-06-10 Schering Corporation Compounds for the inhibition of farnesyl protein transferase
US6372909B1 (en) 1998-11-20 2002-04-16 Schering Corporation Synthesis of intermediates useful in preparing tricyclic compounds
CA2352204C (en) * 1998-11-20 2007-10-16 Schering Corporation Enantioselective alkylation of tricyclic compounds
US6307048B1 (en) 1998-11-20 2001-10-23 Schering Corporation Enantioselective alkylation of tricyclic compounds

Also Published As

Publication number Publication date
CN1717392A (zh) 2006-01-04
JP4679150B2 (ja) 2011-04-27
US7049440B2 (en) 2006-05-23
EP2189447A1 (de) 2010-05-26
CY1107481T1 (el) 2013-04-18
EP1556358A2 (de) 2005-07-27
EP1780203A3 (de) 2007-07-11
ZA200502581B (en) 2006-02-20
AU2003277194A8 (en) 2004-04-23
ATE461921T1 (de) 2010-04-15
ATE365157T1 (de) 2007-07-15
JP2010202656A (ja) 2010-09-16
CN101289425A (zh) 2008-10-22
DE60314535D1 (de) 2007-08-02
EP2189447B1 (de) 2011-11-16
AU2003277194A1 (en) 2004-04-23
WO2004031153A3 (en) 2004-07-15
CN100404510C (zh) 2008-07-23
US20040122232A1 (en) 2004-06-24
US7582763B2 (en) 2009-09-01
DE60331870D1 (de) 2010-05-06
ES2285252T3 (es) 2007-11-16
JP2006511481A (ja) 2006-04-06
MXPA05003518A (es) 2005-06-03
SI1556358T1 (sl) 2007-10-31
CA2501292A1 (en) 2004-04-15
EP1780203B1 (de) 2010-03-24
EP1780203A2 (de) 2007-05-02
PT1556358E (pt) 2007-09-25
EP1556358B1 (de) 2007-06-20
ES2374705T3 (es) 2012-02-21
HK1072773A1 (en) 2005-09-09
DK1556358T3 (da) 2007-09-10
AR041466A1 (es) 2005-05-18
ES2340806T3 (es) 2010-06-09
HK1101910A1 (en) 2007-11-02
WO2004031153A2 (en) 2004-04-15
US20060074241A1 (en) 2006-04-06
CN101289425B (zh) 2011-04-13
DE60314535T2 (de) 2008-02-21

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