ATE530549T1 - 9-substituierte 8-oxoadeninverbindungen als modulatoren des toll-like-receptor (tlr7) - Google Patents

9-substituierte 8-oxoadeninverbindungen als modulatoren des toll-like-receptor (tlr7)

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Publication number
ATE530549T1
ATE530549T1 AT08718791T AT08718791T ATE530549T1 AT E530549 T1 ATE530549 T1 AT E530549T1 AT 08718791 T AT08718791 T AT 08718791T AT 08718791 T AT08718791 T AT 08718791T AT E530549 T1 ATE530549 T1 AT E530549T1
Authority
AT
Austria
Prior art keywords
tlr7
toll
modulators
receptor
substituted
Prior art date
Application number
AT08718791T
Other languages
English (en)
Inventor
Roger Bonnert
Thomas Mcinally
Stephen Thom
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE530549T1 publication Critical patent/ATE530549T1/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
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AT08718791T 2007-03-19 2008-03-19 9-substituierte 8-oxoadeninverbindungen als modulatoren des toll-like-receptor (tlr7) ATE530549T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89550007P 2007-03-19 2007-03-19
PCT/GB2008/000952 WO2008114006A1 (en) 2007-03-19 2008-03-19 9-substituted-8-oxo-adenine compounds as toll-like receptor (tlr7) modulators

Publications (1)

Publication Number Publication Date
ATE530549T1 true ATE530549T1 (de) 2011-11-15

Family

ID=39535206

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08718791T ATE530549T1 (de) 2007-03-19 2008-03-19 9-substituierte 8-oxoadeninverbindungen als modulatoren des toll-like-receptor (tlr7)

Country Status (6)

Country Link
US (1) US8063051B2 (de)
EP (1) EP2139894B1 (de)
JP (1) JP5329444B2 (de)
AT (1) ATE530549T1 (de)
ES (1) ES2373616T3 (de)
WO (1) WO2008114006A1 (de)

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