UY30572A1 - N-(1-ftalazin-1-il-piperidin-4-il)-amidas como moduladores del receptor ep2 - Google Patents

N-(1-ftalazin-1-il-piperidin-4-il)-amidas como moduladores del receptor ep2

Info

Publication number
UY30572A1
UY30572A1 UY30572A UY30572A UY30572A1 UY 30572 A1 UY30572 A1 UY 30572A1 UY 30572 A UY30572 A UY 30572A UY 30572 A UY30572 A UY 30572A UY 30572 A1 UY30572 A1 UY 30572A1
Authority
UY
Uruguay
Prior art keywords
piperidin
ftalazin
amidas
modulators
receiver
Prior art date
Application number
UY30572A
Other languages
English (en)
Inventor
Antonius Ter Laak
Tim Wintermantel
Olaf Peters
Bernhard Lindenthal
Gernot Langer
Marcus Koppitz
Bernd Buchmann
Nico Braeuer
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of UY30572A1 publication Critical patent/UY30572A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

La presente invencion se refiere a ftalazin-1-il-piperidin-4-il-amidas de la formula general I, a procedimientos para su preparacion, así como a su uso para la preparacion de agentes farmacéuticos para el tratamiento de enfermedades e indicaciones que están relacionadas con el receptor EP2.
UY30572A 2006-09-07 2007-09-05 N-(1-ftalazin-1-il-piperidin-4-il)-amidas como moduladores del receptor ep2 UY30572A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06090159A EP1900731A1 (de) 2006-09-07 2006-09-07 N-(1-Phthalazin-1-yl-piperidin-4-yl)-amide als EP2-Rezeptor Modulatoren

Publications (1)

Publication Number Publication Date
UY30572A1 true UY30572A1 (es) 2008-05-02

Family

ID=37649444

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30572A UY30572A1 (es) 2006-09-07 2007-09-05 N-(1-ftalazin-1-il-piperidin-4-il)-amidas como moduladores del receptor ep2

Country Status (7)

Country Link
US (1) US20080146576A1 (es)
EP (1) EP1900731A1 (es)
AR (1) AR062695A1 (es)
CL (1) CL2007002578A1 (es)
TW (1) TW200817356A (es)
UY (1) UY30572A1 (es)
WO (1) WO2008028689A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2723042A1 (en) 2008-04-29 2009-11-05 Eli Lilly And Company Disubstituted phthalazine hedgehog pathway antagonists
EP2149554A1 (de) 2008-07-30 2010-02-03 Bayer Schering Pharma Aktiengesellschaft Indolylamide als Modulatoren des EP2-Rezeptors
EP2149551A1 (de) 2008-07-30 2010-02-03 Bayer Schering Pharma AG N-(Indol-3-ylalkyl)-(hetero)arylamidderivate als Modulatoren des EP2-Rezeptors
EP2149552A1 (de) 2008-07-30 2010-02-03 Bayer Schering Pharma AG 5,6 substituierte Benzamid-Derivate als Modulatoren des EP2-Rezeptors
DK2364185T3 (da) 2008-11-03 2013-06-03 Lilly Co Eli Disubstituerede phthalazin-hedgehog-pathway-antagonister
EP2358703B1 (en) 2008-11-17 2013-12-25 Eli Lilly and Company Tetrasubstituted pyridazines hedgehog pathway antagonists
PT2358698E (pt) 2008-11-17 2012-10-24 Lilly Co Eli Antagonistas da via hedgehog de piridazina tetrasubstituída
AR077014A1 (es) * 2009-06-19 2011-07-27 Lilly Co Eli Compuesto derivado de ftalazina 1,4-disustituida, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para el tratamiento de cancer
DE102009049662A1 (de) 2009-10-13 2011-04-14 Bayer Schering Pharma Aktiengesellschaft 2,5-Disubstituierte 2H-Indazole als EP2-Rezeptor-Antagonisten
AR083199A1 (es) 2010-09-29 2013-02-06 Intervet Internationale B V Compuestos de n-heteroarilo con unidad de puente ciclico
CN105294549B (zh) 2010-09-29 2017-12-26 英特维特国际股份有限公司 N‑杂芳基化合物
US9045435B2 (en) 2010-10-05 2015-06-02 Purdue Pharma, L.P. Quinazoline compounds as sodium channel blockers
TW201326154A (zh) 2011-11-28 2013-07-01 拜耳知識產權公司 作為ｅｐ２受體拮抗劑之新穎２ｈ－吲唑
AU2013241854B2 (en) 2012-03-28 2017-11-02 Intervet International B.V. Heteroaryl compounds with cyclic bridging unit for use in the treatment helminth infection
EP2831042B1 (en) 2012-03-28 2019-07-31 Intervet International B.V. Heteroaryl compounds with a-cyclic bridging unit
GB201309508D0 (en) * 2013-05-28 2013-07-10 Redx Pharma Ltd Compounds
ES2670550T3 (es) 2013-10-14 2018-05-30 Eisai R&D Management Co., Ltd. Derivados de quinolina selectivamente sustituidos
PT3057964T (pt) 2013-10-14 2020-02-25 Eisai R&D Man Co Ltd Compostos de quinolina seletivamente substituídos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN148482B (es) * 1977-06-03 1981-03-07 Pfizer
US4370328A (en) * 1977-11-03 1983-01-25 Pfizer Inc. Cardiac stimulant 1-(3- or 4-substituted piperidino)phthalazines
WO2003030911A1 (en) * 2001-10-08 2003-04-17 Medical Research Council Use of prostaglandin e synthase inhibitors, or ep2 or ep4 receptor antagonists, in the treatment of a pathological condition of the uterus

Also Published As

Publication number Publication date
WO2008028689A1 (en) 2008-03-13
CL2007002578A1 (es) 2008-07-04
US20080146576A1 (en) 2008-06-19
TW200817356A (en) 2008-04-16
EP1900731A1 (de) 2008-03-19
AR062695A1 (es) 2008-11-26

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20170726