ATE528283T1 - Verfahren zur herstellung von n-(2-amino-1,2- dicyanovinyl)imidaten und verfahren zur herstellung von aminoimidazolderivaten - Google Patents
Verfahren zur herstellung von n-(2-amino-1,2- dicyanovinyl)imidaten und verfahren zur herstellung von aminoimidazolderivatenInfo
- Publication number
- ATE528283T1 ATE528283T1 AT08740560T AT08740560T ATE528283T1 AT E528283 T1 ATE528283 T1 AT E528283T1 AT 08740560 T AT08740560 T AT 08740560T AT 08740560 T AT08740560 T AT 08740560T AT E528283 T1 ATE528283 T1 AT E528283T1
- Authority
- AT
- Austria
- Prior art keywords
- producing
- dicyanovinyl
- amino
- imidates
- following formula
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 5
- DEPDDPLQZYCHOH-UHFFFAOYSA-N 1h-imidazol-2-amine Chemical class NC1=NC=CN1 DEPDDPLQZYCHOH-UHFFFAOYSA-N 0.000 title abstract 2
- 150000002463 imidates Chemical class 0.000 title abstract 2
- 238000007363 ring formation reaction Methods 0.000 abstract 2
- DPZSNGJNFHWQDC-ARJAWSKDSA-N (z)-2,3-diaminobut-2-enedinitrile Chemical compound N#CC(/N)=C(/N)C#N DPZSNGJNFHWQDC-ARJAWSKDSA-N 0.000 abstract 1
- DVNYTAVYBRSTGK-UHFFFAOYSA-N 5-aminoimidazole-4-carboxamide Chemical compound NC(=O)C=1N=CNC=1N DVNYTAVYBRSTGK-UHFFFAOYSA-N 0.000 abstract 1
- 210000005097 arteria cerebelosa anteroinferior Anatomy 0.000 abstract 1
- JOWVYROMILUUHH-UHFFFAOYSA-N n'-(2-amino-1,2-dicyanoethenyl)methanimidamide Chemical compound NC=NC(C#N)=C(N)C#N JOWVYROMILUUHH-UHFFFAOYSA-N 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/12—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to hydrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/04—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines without replacement of the other oxygen atom of the carboxyl group, e.g. imino-ethers
- C07C257/06—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines without replacement of the other oxygen atom of the carboxyl group, e.g. imino-ethers having carbon atoms of imino-carboxyl groups bound to hydrogen atoms, to acyclic carbon atoms, or to carbon atoms of rings other than six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007111038A JP5004643B2 (ja) | 2007-04-19 | 2007-04-19 | Ｎ−（２−アミノ−１，２−ジシアノビニル）ホルムアミジンの製造方法 |
| JP2007111041A JP5112737B2 (ja) | 2007-04-19 | 2007-04-19 | アミノイミダゾール誘導体の製造方法 |
| JP2007111039A JP5064872B2 (ja) | 2007-04-19 | 2007-04-19 | Ｎ−（２−アミノ−１，２−ジシアノビニル）イミデート類の製造方法 |
| PCT/JP2008/057490 WO2008133169A1 (ja) | 2007-04-19 | 2008-04-17 | Ｎ－（２－アミノ－１，２－ジシアノビニル）イミデート類、ｎ－（２－アミノ－１，２－ジシアノビニル）ホルムアミジン、およびアミノイミダゾール誘導体の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE528283T1 true ATE528283T1 (de) | 2011-10-15 |
Family
ID=39925625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08740560T ATE528283T1 (de) | 2007-04-19 | 2008-04-17 | Verfahren zur herstellung von n-(2-amino-1,2- dicyanovinyl)imidaten und verfahren zur herstellung von aminoimidazolderivaten |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US8273899B2 (de) |
| EP (1) | EP2138480B1 (de) |
| KR (3) | KR101161602B1 (de) |
| CN (2) | CN102850238B (de) |
| AT (1) | ATE528283T1 (de) |
| WO (1) | WO2008133169A1 (de) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3778446A (en) * | 1971-07-23 | 1973-12-11 | Du Pont | 2-substituted-4,5-dicyanoimidazoles and their preparation from diaminomaleonitrile |
| AU7385994A (en) * | 1993-07-26 | 1995-02-20 | Ciba-Geigy Ag | Process for the preparation of substituted 4,6-diamino-5-cyanopyrimidines |
| JP4768109B2 (ja) | 1999-09-20 | 2011-09-07 | 日本曹達株式会社 | １ｈ−２−置換−４（５）−アミノ−５（４）−カルボキサミド−イミダゾールの製造方法 |
| JP4699582B2 (ja) | 1999-11-19 | 2011-06-15 | 日本曹達株式会社 | １ｈ−４（５）−アミノイミダゾール−５（４）−カルボキサミドの製造方法 |
| KR100538958B1 (ko) * | 1999-09-20 | 2005-12-26 | 닛뽕소다 가부시키가이샤 | 4(5)-아미노-5(4)-카르복사미도이미다졸 및 그의 중간체의 제조방법 |
| JP4461468B2 (ja) | 2000-04-18 | 2010-05-12 | 日本曹達株式会社 | Ｎ−（２−アミノ−１，２−ジシアノビニル）ギ酸誘導体の製造方法 |
| JP4790901B2 (ja) | 2000-11-17 | 2011-10-12 | 日本曹達株式会社 | ４−アミノ−５−シアノイミダゾール誘導体及びその中間体の製造方法 |
| JP2003246779A (ja) * | 2001-12-20 | 2003-09-02 | Nippon Soda Co Ltd | ４，５−ジアルコキシカルボニル又は４，５−ジシアノイミダゾールの製造方法 |
| JP4261839B2 (ja) | 2002-08-19 | 2009-04-30 | 日本曹達株式会社 | アミノイミダゾール化合物の製造方法 |
| AU2003272991A1 (en) * | 2002-10-16 | 2004-05-04 | Nippon Soda Co., Ltd. | Process for producing n-(2-amino-1,2-dicyanovinyl)formamidine |
-
2008
- 2008-04-17 WO PCT/JP2008/057490 patent/WO2008133169A1/ja not_active Ceased
- 2008-04-17 AT AT08740560T patent/ATE528283T1/de not_active IP Right Cessation
- 2008-04-17 CN CN201210295851.4A patent/CN102850238B/zh not_active Expired - Fee Related
- 2008-04-17 KR KR1020117015447A patent/KR101161602B1/ko not_active Expired - Fee Related
- 2008-04-17 EP EP08740560A patent/EP2138480B1/de not_active Not-in-force
- 2008-04-17 CN CN2012102958548A patent/CN102850277A/zh active Pending
- 2008-04-17 KR KR1020097021314A patent/KR101132590B1/ko not_active Expired - Fee Related
- 2008-04-17 KR KR1020117015448A patent/KR101156497B1/ko not_active Expired - Fee Related
- 2008-04-17 US US12/450,730 patent/US8273899B2/en not_active Expired - Fee Related
-
2012
- 2012-01-31 US US13/363,062 patent/US8258333B2/en not_active Expired - Fee Related
- 2012-01-31 US US13/363,091 patent/US8785654B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR101161602B1 (ko) | 2012-07-03 |
| US8785654B2 (en) | 2014-07-22 |
| CN102850238B (zh) | 2015-08-19 |
| EP2138480A1 (de) | 2009-12-30 |
| EP2138480A4 (de) | 2010-06-09 |
| US20120142957A1 (en) | 2012-06-07 |
| US20120130083A1 (en) | 2012-05-24 |
| KR20090122988A (ko) | 2009-12-01 |
| EP2138480B1 (de) | 2011-10-12 |
| CN102850238A (zh) | 2013-01-02 |
| US8273899B2 (en) | 2012-09-25 |
| WO2008133169A1 (ja) | 2008-11-06 |
| US20100087655A1 (en) | 2010-04-08 |
| KR101132590B1 (ko) | 2012-04-10 |
| KR20110086191A (ko) | 2011-07-27 |
| CN102850277A (zh) | 2013-01-02 |
| US8258333B2 (en) | 2012-09-04 |
| KR101156497B1 (ko) | 2012-06-18 |
| KR20110086770A (ko) | 2011-07-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE534629T1 (de) | Verfahren und verbindungen zur herstellung von cc-1065-analoga | |
| ES2531324T3 (es) | Intermedio para producir un derivado de gamma-aminoácido bicíclico | |
| TW200914429A (en) | Method for preparing 5-haloalkyl-4,5-dihydroisoxazole derivatives | |
| TW200640859A (en) | Substituted bis aryl and heteroaryl compounds as selective 5HT2A antagonists | |
| WO2005076990A3 (en) | Process for preparing 2-aminothiazole-5-carboxamides useful as kinase inhibitors | |
| MX2012015023A (es) | Derivado novedoso de nicotinamida o sal del mismo. | |
| WO2006021379A8 (de) | Dihydropteridinonderivate, verfahren zu deren herstellung und deren verwendung als arzneimittel | |
| CY1107846T1 (el) | Παραγωγα κιναζολινονης χρησιμα ως βανιλλοειδεις ανταγωνιστες | |
| ATE542803T1 (de) | Verfahren zur herstellung von dihydrochinazolinen | |
| WO2006021378A8 (de) | Dihydropteridinonderivate, verfahren zu deren herstellung und deren verwendung als arzneimittel | |
| MX2009007436A (es) | Derivados espirociclicos de acido tetronico. | |
| WO2009018065A3 (en) | Novel glucokinase activators and methods of using same | |
| NZ596025A (en) | [4-(6-halo-7-substituted-2,4-dioxo-1,4-dihydro-2h-quinazolin-3-yl)-phenyl]-5-chloro-thiophen-2-yl-sulfonylureas and forms and methods related thereto | |
| DE602006009698D1 (de) | Verfahren zur herstellung von expoxybutanol-zwischenprodukten | |
| MY148769A (en) | Process for the synthesis of derivatives of 3-amino-tetrahydrofuran-3-carboxylic acid and use thereof as medicaments | |
| DE602007008691D1 (de) | Cyclische sulfone, die zur verwendung als bace-inhibitoren geeignet sind | |
| UA100417C2 (en) | Method for producing bicyclic guanidines by use of a cyclic thiourea | |
| ATE525364T1 (de) | Verfahren zur herstellung von 3,6-dihydro-1,3,5- triazin-derivaten | |
| DE602006010365D1 (de) | Verfahren zur herstellung von isocyanatosilan und silylisocyanurat | |
| ATE532516T1 (de) | Verfahren zur synthese von glyt-1-hemmern | |
| ATE528283T1 (de) | Verfahren zur herstellung von n-(2-amino-1,2- dicyanovinyl)imidaten und verfahren zur herstellung von aminoimidazolderivaten | |
| IL183805A0 (en) | Process for preparing substituted thiophenesulfonyl isocyanates | |
| AR046851A1 (es) | Procesos para la preparacion de pirazolo(1,5-alfa)-1,3,5-triazinas e intermedios de las mismas | |
| TW200719889A (en) | Amino acid derivatives | |
| ATE523490T1 (de) | Verfahren zur herstellung von pleuromutilinen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |