ATE523587T1 - Eigenschaften neuronaler vorläuferzellen zeigende zellen - Google Patents

Eigenschaften neuronaler vorläuferzellen zeigende zellen

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Publication number
ATE523587T1
ATE523587T1 AT05735066T AT05735066T ATE523587T1 AT E523587 T1 ATE523587 T1 AT E523587T1 AT 05735066 T AT05735066 T AT 05735066T AT 05735066 T AT05735066 T AT 05735066T AT E523587 T1 ATE523587 T1 AT E523587T1
Authority
AT
Austria
Prior art keywords
cells
pronector
neuronal
showing characteristics
stem cells
Prior art date
Application number
AT05735066T
Other languages
English (en)
Inventor
Mari Dezawa
Original Assignee
Sanbio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanbio Inc filed Critical Sanbio Inc
Application granted granted Critical
Publication of ATE523587T1 publication Critical patent/ATE523587T1/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/415—Wnt; Frizzeled
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/727—Kinases (EC 2.7.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
    • C12N2506/1353—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from bone marrow mesenchymal stem cells (BM-MSC)

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT05735066T 2004-04-12 2005-04-07 Eigenschaften neuronaler vorläuferzellen zeigende zellen ATE523587T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56161304P 2004-04-12 2004-04-12
PCT/US2005/011670 WO2005100552A2 (en) 2004-04-12 2005-04-07 Cells exhibiting neuronal progenitor cell characteristics

Publications (1)

Publication Number Publication Date
ATE523587T1 true ATE523587T1 (de) 2011-09-15

Family

ID=35150551

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05735066T ATE523587T1 (de) 2004-04-12 2005-04-07 Eigenschaften neuronaler vorläuferzellen zeigende zellen

Country Status (13)

Country Link
US (5) US20060251624A1 (de)
EP (2) EP2314674A1 (de)
JP (2) JP2007532112A (de)
KR (2) KR20130062359A (de)
CN (1) CN1973031B (de)
AT (1) ATE523587T1 (de)
AU (1) AU2005233582B2 (de)
CA (2) CA2562198C (de)
DK (1) DK1737950T3 (de)
ES (1) ES2372501T3 (de)
PL (1) PL1737950T3 (de)
PT (1) PT1737950E (de)
WO (1) WO2005100552A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1737950T3 (pl) * 2004-04-12 2012-02-29 Sanbio Inc Komórki wykazujące cechy neuronalnych komórek progenitorowych
US20060110440A1 (en) * 2004-10-22 2006-05-25 Kiminobu Sugaya Method and system for biasing cellular development
US20060216276A1 (en) * 2005-03-07 2006-09-28 Mari Dezawa Use of materials for treatment of central nervous system lesions
CA2667582A1 (en) 2006-10-27 2008-05-02 The University Of Western Ontario Method of treating conditions associated with proteoglycan production
WO2009023251A1 (en) * 2007-08-15 2009-02-19 Sanbio, Inc. Methods and compositions for treating neural degeneration
DK2222839T3 (en) 2007-12-03 2015-12-21 Sanbio Inc Methods and compositions for modulating differentiation of pluripotent cells
US10702554B2 (en) * 2007-12-03 2020-07-07 Sanbio, Inc. Extracellular matrix from pluripotent cells
WO2009134409A2 (en) 2008-04-30 2009-11-05 Sanbio, Inc. Neural regenerating cells with alterations in dna methylation
EP2694080B1 (de) 2011-04-06 2018-03-14 SanBio, Inc. Verfahren und zusammensetzungen zur modulierung der peripheren immunfunktionen
CN112386681A (zh) 2012-01-27 2021-02-23 桑比欧公司 用于调节血管生成和血管发生的方法和组合物
EP2849766B1 (de) 2012-05-16 2019-03-06 SanBio, Inc. Zellen zur verwendung in der behandlung von traumatischer gehirnschäden
EP2906293B1 (de) 2012-10-09 2018-12-12 SanBio, Inc. Verfahren und zusammensetzungen zur behandlung von netzhautdegeneration
WO2014176606A1 (en) 2013-04-26 2014-10-30 Memorial Sloan-Kettering Center Center Cortical interneurons and other neuronal cells produced by the directed differentiation of pluripotent and multipotent cells
WO2016161290A1 (en) 2015-04-01 2016-10-06 Sanbio, Inc. Methods and compositions for stimulation of cell proliferation and provision of biologically active mixtures of fgf2 isoforms
CA3030866A1 (en) 2016-07-21 2018-01-25 Sanbio, Inc. Msc growth predictor assays
JP7220149B2 (ja) 2016-12-28 2023-02-09 サンバイオ，インコーポレイティド 細胞送達システム及びその動作方法

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US5276204A (en) 1988-11-09 1994-01-04 Henkel Kommanditgesellschaft Auf Aktien Fatty alcohol mixtures and ethoxylates thereof showing improved low-temperature behavior
JPH031260A (ja) 1989-05-30 1991-01-07 Hitachi Ltd 計算機方式
US6653134B2 (en) 1995-03-28 2003-11-25 Cp Hahnemann University Isolated stromal cells for use in the treatment of diseases of the central nervous system
US6395205B1 (en) * 1996-07-17 2002-05-28 Chemical Lime Company Method of manufacturing an aerated autoclaved concrete material
WO1999056759A1 (en) 1998-05-07 1999-11-11 University Of South Florida Bone marrow cells as a source of neurons for brain and spinal cord repair
US7105150B2 (en) * 1999-02-12 2006-09-12 Stemcells California, Inc. In vivo screening methods using enriched neural stem cells
US6080747A (en) * 1999-03-05 2000-06-27 Hughes Institute JAK-3 inhibitors for treating allergic disorders
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KR100449141B1 (ko) * 2001-04-19 2004-09-21 (주)라이프코드 간엽 간세포를 신경세포로 분화시키는 방법
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CA2463930A1 (en) * 2001-08-08 2003-02-20 Celmed Biosciences Usa, Inc. Compositions and methods for isolation, propagation, and differentiation of human stem cells and uses thereof
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US20040062753A1 (en) * 2002-09-27 2004-04-01 Alireza Rezania Composite scaffolds seeded with mammalian cells
PL1737950T3 (pl) * 2004-04-12 2012-02-29 Sanbio Inc Komórki wykazujące cechy neuronalnych komórek progenitorowych

Also Published As

Publication number Publication date
US20090324561A1 (en) 2009-12-31
US20110229442A1 (en) 2011-09-22
WO2005100552A3 (en) 2006-10-12
ES2372501T3 (es) 2012-01-20
US20060251624A1 (en) 2006-11-09
DK1737950T3 (da) 2011-12-05
US20150267169A1 (en) 2015-09-24
US20130071924A1 (en) 2013-03-21
KR101277310B1 (ko) 2013-06-25
PL1737950T3 (pl) 2012-02-29
US9441199B2 (en) 2016-09-13
JP2012130348A (ja) 2012-07-12
CA2929754A1 (en) 2005-10-27
CN1973031A (zh) 2007-05-30
AU2005233582A1 (en) 2005-10-27
KR20070015542A (ko) 2007-02-05
CA2562198A1 (en) 2005-10-27
EP2314674A1 (de) 2011-04-27
CA2562198C (en) 2017-05-30
JP5756039B2 (ja) 2015-07-29
PT1737950E (pt) 2011-12-22
KR20130062359A (ko) 2013-06-12
EP1737950B1 (de) 2011-09-07
CN1973031B (zh) 2011-11-02
EP1737950B9 (de) 2012-04-18
EP1737950A2 (de) 2007-01-03
WO2005100552A2 (en) 2005-10-27
AU2005233582B2 (en) 2009-01-29
JP2007532112A (ja) 2007-11-15

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