DK1645626T3 - Cellelinie - Google Patents

Cellelinie

Info

Publication number
DK1645626T3
DK1645626T3 DK05255932T DK05255932T DK1645626T3 DK 1645626 T3 DK1645626 T3 DK 1645626T3 DK 05255932 T DK05255932 T DK 05255932T DK 05255932 T DK05255932 T DK 05255932T DK 1645626 T3 DK1645626 T3 DK 1645626T3
Authority
DK
Denmark
Prior art keywords
cell line
cell lines
relates
present
accession nos
Prior art date
Application number
DK05255932T
Other languages
English (en)
Inventor
John Sinden
Kenneth Pollack
Paul Stroemer
Original Assignee
Reneuron Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0421753A external-priority patent/GB0421753D0/en
Priority claimed from GB0425767A external-priority patent/GB0425767D0/en
Priority claimed from GB0427830A external-priority patent/GB0427830D0/en
Application filed by Reneuron Ltd filed Critical Reneuron Ltd
Application granted granted Critical
Publication of DK1645626T3 publication Critical patent/DK1645626T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/46—Amines, e.g. putrescine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C12N2501/392—Sexual steroids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells
DK05255932T 2004-09-30 2005-09-23 Cellelinie DK1645626T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0421753A GB0421753D0 (en) 2004-09-30 2004-09-30 Cell line
GB0425767A GB0425767D0 (en) 2004-11-23 2004-11-23 Cell line
GB0427830A GB0427830D0 (en) 2004-12-20 2004-12-20 Cell line

Publications (1)

Publication Number Publication Date
DK1645626T3 true DK1645626T3 (da) 2008-01-21

Family

ID=35744948

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05255932T DK1645626T3 (da) 2004-09-30 2005-09-23 Cellelinie

Country Status (9)

Country Link
US (3) US7416888B2 (da)
EP (1) EP1645626B1 (da)
JP (1) JP5036156B2 (da)
AT (1) ATE373081T1 (da)
AU (1) AU2005218041B2 (da)
CA (1) CA2521421C (da)
DE (1) DE602005002430T2 (da)
DK (1) DK1645626T3 (da)
ES (1) ES2294650T3 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
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GB9518606D0 (en) * 1995-09-12 1995-11-15 Inst Of Psychiatry Neural transplantation
EP1645626B1 (en) * 2004-09-30 2007-09-12 Reneuron Limited Cell line
GB0822246D0 (en) 2008-12-05 2009-01-14 Reneuron Ltd Composition
GB0902034D0 (en) * 2009-02-06 2009-03-11 Reneuron Ltd Method
WO2011015573A1 (en) 2009-08-03 2011-02-10 Galapagos Nv Molecular targets and compounds, and methods to identify the same, useful in the treatment of neurodegenerative diseases
GB201011589D0 (en) * 2010-07-09 2010-08-25 Reneuron Ltd Therapeutic cells
GB201302468D0 (en) 2013-02-12 2013-03-27 Reneuron Ltd Stem cell product
AU2013245406B2 (en) * 2012-04-03 2017-07-20 Reneuron Limited Stem cell microparticles
CN104703609B (zh) 2012-07-19 2019-02-19 兰诺龙有限公司 干细胞微粒
SG11201506284RA (en) 2013-02-12 2015-09-29 Reneuron Ltd Method of producing microparticles
GB201317887D0 (en) 2013-10-09 2013-11-20 Reneuron Ltd Product
GB201317889D0 (en) 2013-10-09 2013-11-20 Reneuron Ltd Product and use
US20200108100A1 (en) * 2018-10-08 2020-04-09 Reneuron Limited Neural stem cell therapy for stroke
US20210371828A1 (en) 2018-10-12 2021-12-02 Reneuron Limited Induced pluripotent cell comprising a controllable transgene for conditional immortalization
GB201911464D0 (en) 2019-08-09 2019-09-25 Reneuron Ltd Genetic modification site
GB201919021D0 (en) 2019-12-20 2020-02-05 Reneuron Ltd Nucleic acid constructs for delivering polynucleotides into exosomes
GB202005494D0 (en) 2020-04-15 2020-05-27 Reneuron Ltd Induced pluripotent cell comprising a contollable transgene for conditional immortalisation
GB202114441D0 (en) 2021-10-08 2021-11-24 Reneuron Ltd Proteins and extracellular vesicles

Family Cites Families (39)

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NZ226750A (en) 1987-10-29 1990-09-26 Amrad Corp Ltd Immortalisation of neural precursor cells by introducing a retrovirus vector containing a myc-oncogene
DE68907220T2 (de) 1988-04-12 1994-01-27 Massachusetts Inst Technology Verfahren zur manipulation des zelltyps von eukaryonten.
US5270191A (en) 1988-04-12 1993-12-14 Massachusetts Institute Of Technology Method for manipulation of the cell types of eukaryotes
US5399493A (en) 1989-06-15 1995-03-21 The Regents Of The University Of Michigan Methods and compositions for the optimization of human hematopoietic progenitor cell cultures
WO1991009936A1 (en) 1989-12-26 1991-07-11 Hana Biologics, Inc. Proliferated neuron progenitor cell product and process
US5612211A (en) 1990-06-08 1997-03-18 New York University Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors
US5851832A (en) 1991-07-08 1998-12-22 Neurospheres, Ltd. In vitro growth and proliferation of multipotent neural stem cells and their progeny
WO1993001275A1 (en) 1991-07-08 1993-01-21 Neurospheres Ltd. NOVEL GROWTH FACTOR-RESPONSIVE PROGENITOR CELLS WHICH CAN BE PROLIFERATED $i(IN VITRO)
WO1993018137A1 (en) 1992-03-04 1993-09-16 Systemix, Inc. Culturing of hematopoietic stem cells and their genetic engineering
US5753491A (en) 1993-04-13 1998-05-19 Us Health Use of neuro-derived fetal cell lines for transplantation therapy
ES2170096T3 (es) 1993-04-13 2002-08-01 Us Gov Health & Human Serv Uso de lineas celulares fetales neuroderivadas para terapia de trasplantes.
EP0792351B1 (en) 1994-11-08 2004-03-10 Cellfactors PLC Method for producing a human neural cell line
KR970707272A (ko) 1994-11-14 1997-12-01 스코트 디. 코르맥 신경 간세포 증식 조절 방법(regulation of neural stem cell proliferation)
US5843780A (en) 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
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US5588692A (en) 1995-10-11 1996-12-31 General Motors Corporation Push-out vehicle side door
EP0773287A1 (en) * 1995-11-07 1997-05-14 Bayer Ag Immortalised embryonic hyppocampal cells and their use
US5770414A (en) * 1996-02-20 1998-06-23 The Regents Of The University Of California Regulatable retrovirus system for genetic modification of cells
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JP2002513545A (ja) 1998-05-07 2002-05-14 ザ ユニヴァーシティー オブ サウス フロリダ 脳および脊髄修復のためのニューロン源としての骨髄細胞
US5958767A (en) 1998-08-14 1999-09-28 The Children's Medical Center Corp. Engraftable human neural stem cells
GB9904281D0 (en) 1999-02-24 1999-04-21 Reneuron Ltd Transplantation
GB9907243D0 (en) 1999-03-29 1999-05-26 Reneuron Ltd Therapy
US6399384B1 (en) 1999-09-17 2002-06-04 Reneuron Limited Conditional immortalization of cells
US6465215B1 (en) 1999-12-14 2002-10-15 Reneuron Limited Identification of cells for transplantation
CA2393071A1 (en) * 1999-12-07 2001-06-14 Monash University Long-term cell culture compositions and genetically modified animals derived therefrom
EP1263930A4 (en) 2000-03-09 2004-07-21 Saneron Ccel Therapeutics Inc BLOOD CELLS OF THE HUMAN UBILICAL CORD USED AS A SOURCE OF NEURAL TISSUE FOR REPAIRING THE BRAIN AND THE SPINAL CORD
GB0005856D0 (en) * 2000-03-10 2000-05-03 Reneuron Ltd Genetic constructs
US7250294B2 (en) 2000-05-17 2007-07-31 Geron Corporation Screening small molecule drugs using neural cells differentiated from human embryonic stem cells
US7049072B2 (en) 2000-06-05 2006-05-23 University Of South Florida Gene expression analysis of pluri-differentiated mesenchymal progenitor cells and methods for diagnosing a leukemic disease state
AU2001264763A1 (en) 2000-06-05 2001-12-17 University Of South Florida Human mesenchymal progenitor cell
WO2003029432A2 (en) 2001-10-03 2003-04-10 University Of South Florida Human mesenchymal progenitor cell
GB0125773D0 (en) 2001-10-26 2001-12-19 Reneuron Ltd Constructs
US20040185429A1 (en) * 2002-12-09 2004-09-23 Judith Kelleher-Andersson Method for discovering neurogenic agents
EP1645626B1 (en) * 2004-09-30 2007-09-12 Reneuron Limited Cell line

Also Published As

Publication number Publication date
CA2521421A1 (en) 2006-03-30
US7416888B2 (en) 2008-08-26
AU2005218041B2 (en) 2010-09-16
JP5036156B2 (ja) 2012-09-26
AU2005218041A1 (en) 2006-04-13
ES2294650T3 (es) 2008-04-01
US20080118479A1 (en) 2008-05-22
EP1645626A1 (en) 2006-04-12
DE602005002430D1 (de) 2007-10-25
ATE373081T1 (de) 2007-09-15
JP2006122045A (ja) 2006-05-18
EP1645626B1 (en) 2007-09-12
US7666672B2 (en) 2010-02-23
DE602005002430T2 (de) 2008-06-19
US7419827B2 (en) 2008-09-02
US20060104959A1 (en) 2006-05-18
CA2521421C (en) 2013-08-06
US20060067918A1 (en) 2006-03-30

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