DE602005002430D1 - Zelllinie - Google Patents
ZelllinieInfo
- Publication number
- DE602005002430D1 DE602005002430D1 DE602005002430T DE602005002430T DE602005002430D1 DE 602005002430 D1 DE602005002430 D1 DE 602005002430D1 DE 602005002430 T DE602005002430 T DE 602005002430T DE 602005002430 T DE602005002430 T DE 602005002430T DE 602005002430 D1 DE602005002430 D1 DE 602005002430D1
- Authority
- DE
- Germany
- Prior art keywords
- cell line
- cell lines
- relates
- present
- accession nos
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/46—Amines, e.g. putrescine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
- C12N2501/392—Sexual steroids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Developmental Biology & Embryology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Semiconductor Memories (AREA)
- Semiconductor Lasers (AREA)
- Internal Circuitry In Semiconductor Integrated Circuit Devices (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0421753 | 2004-09-30 | ||
GB0421753A GB0421753D0 (en) | 2004-09-30 | 2004-09-30 | Cell line |
GB0425767 | 2004-11-23 | ||
GB0425767A GB0425767D0 (en) | 2004-11-23 | 2004-11-23 | Cell line |
GB0427830 | 2004-12-20 | ||
GB0427830A GB0427830D0 (en) | 2004-12-20 | 2004-12-20 | Cell line |
Publications (2)
Publication Number | Publication Date |
---|---|
DE602005002430D1 true DE602005002430D1 (de) | 2007-10-25 |
DE602005002430T2 DE602005002430T2 (de) | 2008-06-19 |
Family
ID=35744948
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005002430T Active DE602005002430T2 (de) | 2004-09-30 | 2005-09-23 | Zelllinie |
Country Status (9)
Country | Link |
---|---|
US (3) | US7416888B2 (de) |
EP (1) | EP1645626B1 (de) |
JP (1) | JP5036156B2 (de) |
AT (1) | ATE373081T1 (de) |
AU (1) | AU2005218041B2 (de) |
CA (1) | CA2521421C (de) |
DE (1) | DE602005002430T2 (de) |
DK (1) | DK1645626T3 (de) |
ES (1) | ES2294650T3 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9518606D0 (en) * | 1995-09-12 | 1995-11-15 | Inst Of Psychiatry | Neural transplantation |
DE602005002430T2 (de) * | 2004-09-30 | 2008-06-19 | Reneuron Ltd., Guildford | Zelllinie |
GB0822246D0 (en) | 2008-12-05 | 2009-01-14 | Reneuron Ltd | Composition |
GB0902034D0 (en) | 2009-02-06 | 2009-03-11 | Reneuron Ltd | Method |
WO2011015573A1 (en) | 2009-08-03 | 2011-02-10 | Galapagos Nv | Molecular targets and compounds, and methods to identify the same, useful in the treatment of neurodegenerative diseases |
GB201011589D0 (en) * | 2010-07-09 | 2010-08-25 | Reneuron Ltd | Therapeutic cells |
GB201302468D0 (en) | 2013-02-12 | 2013-03-27 | Reneuron Ltd | Stem cell product |
SG11201406336YA (en) * | 2012-04-03 | 2014-11-27 | Reneuron Ltd | Stem cell microparticles |
CA2879322A1 (en) | 2012-07-19 | 2014-01-23 | Reneuron Limited | Stem cell microparticles |
CA2900897A1 (en) | 2013-02-12 | 2014-08-21 | Reneuron Limited | Method of producing microparticles |
GB201317887D0 (en) | 2013-10-09 | 2013-11-20 | Reneuron Ltd | Product |
GB201317889D0 (en) | 2013-10-09 | 2013-11-20 | Reneuron Ltd | Product and use |
US20200108100A1 (en) * | 2018-10-08 | 2020-04-09 | Reneuron Limited | Neural stem cell therapy for stroke |
US20210371828A1 (en) | 2018-10-12 | 2021-12-02 | Reneuron Limited | Induced pluripotent cell comprising a controllable transgene for conditional immortalization |
GB201911464D0 (en) | 2019-08-09 | 2019-09-25 | Reneuron Ltd | Genetic modification site |
GB201919021D0 (en) | 2019-12-20 | 2020-02-05 | Reneuron Ltd | Nucleic acid constructs for delivering polynucleotides into exosomes |
GB202005494D0 (en) | 2020-04-15 | 2020-05-27 | Reneuron Ltd | Induced pluripotent cell comprising a contollable transgene for conditional immortalisation |
GB202114441D0 (en) | 2021-10-08 | 2021-11-24 | Reneuron Ltd | Proteins and extracellular vesicles |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ226750A (en) | 1987-10-29 | 1990-09-26 | Amrad Corp Ltd | Immortalisation of neural precursor cells by introducing a retrovirus vector containing a myc-oncogene |
US5270191A (en) | 1988-04-12 | 1993-12-14 | Massachusetts Institute Of Technology | Method for manipulation of the cell types of eukaryotes |
JPH03504799A (ja) | 1988-04-12 | 1991-10-24 | マサチューセッツ・インスティチュート・オブ・テクノロジー | 真核細胞の細胞型を操作する方法 |
US5399493A (en) | 1989-06-15 | 1995-03-21 | The Regents Of The University Of Michigan | Methods and compositions for the optimization of human hematopoietic progenitor cell cultures |
WO1991009936A1 (en) | 1989-12-26 | 1991-07-11 | Hana Biologics, Inc. | Proliferated neuron progenitor cell product and process |
US5612211A (en) | 1990-06-08 | 1997-03-18 | New York University | Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors |
US5851832A (en) | 1991-07-08 | 1998-12-22 | Neurospheres, Ltd. | In vitro growth and proliferation of multipotent neural stem cells and their progeny |
CA2113118C (en) | 1991-07-08 | 2002-09-17 | Samuel Weiss | Novel growth factor-responsive progenitor cells which can be proliferated in vitro |
KR950700403A (ko) | 1992-03-04 | 1995-01-16 | 죤 제이. 쉬바르츠 | 조혈 간세포의 배양 및 그것의 유전공학(culturing of hematopoietic stem cells and their genetic engineering) |
EP0696205B1 (de) | 1993-04-13 | 2002-01-23 | GOVERNMENT OF THE UNITED STATES OF AMERICA, as repr. by THE SECR. OF THE DEPT. OF HEALTH AND HUMAN SERVICES AND HIS SUCCESSORS | Verwendung von neuronalen fötalen zellinien für transplantationstherapie |
US5753491A (en) | 1993-04-13 | 1998-05-19 | Us Health | Use of neuro-derived fetal cell lines for transplantation therapy |
WO1996014400A1 (en) | 1994-11-08 | 1996-05-17 | Bradley Michael John Stringer | Human cell-lines |
JPH10509592A (ja) | 1994-11-14 | 1998-09-22 | ニューロスフィアーズ ホウルディングス リミテッド | 神経幹細胞増殖調節 |
US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
GB9517263D0 (en) | 1995-08-23 | 1995-10-25 | Cancer Res Campaign Tech | Expression systems |
GB9518606D0 (en) * | 1995-09-12 | 1995-11-15 | Inst Of Psychiatry | Neural transplantation |
US5588692A (en) | 1995-10-11 | 1996-12-31 | General Motors Corporation | Push-out vehicle side door |
EP0773287A1 (de) * | 1995-11-07 | 1997-05-14 | Bayer Ag | Unsterbliche embryonale Hippocampus-Zellen und deren Verwendung |
US5770414A (en) * | 1996-02-20 | 1998-06-23 | The Regents Of The University Of California | Regulatable retrovirus system for genetic modification of cells |
US7544511B2 (en) * | 1996-09-25 | 2009-06-09 | Neuralstem Biopharmaceuticals Ltd. | Stable neural stem cell line methods |
WO1998007841A1 (en) | 1996-08-19 | 1998-02-26 | University Of Massachusetts | Embryonic or stem-like cell lines produced by cross species nuclear transplantation |
US20020123143A1 (en) | 1997-08-22 | 2002-09-05 | Jean Toma | Multipotent stem cells from peripheral tissues and uses thereof |
US5968829A (en) | 1997-09-05 | 1999-10-19 | Cytotherapeutics, Inc. | Human CNS neural stem cells |
ES2246085T3 (es) | 1998-05-07 | 2006-02-01 | University Of South Florida | Celulas de medula osea como fuente de neuronas util para reparar la medula espinal y el cerebro. |
US5958767A (en) | 1998-08-14 | 1999-09-28 | The Children's Medical Center Corp. | Engraftable human neural stem cells |
GB9904281D0 (en) | 1999-02-24 | 1999-04-21 | Reneuron Ltd | Transplantation |
GB9907243D0 (en) | 1999-03-29 | 1999-05-26 | Reneuron Ltd | Therapy |
US6399384B1 (en) | 1999-09-17 | 2002-06-04 | Reneuron Limited | Conditional immortalization of cells |
US6465215B1 (en) | 1999-12-14 | 2002-10-15 | Reneuron Limited | Identification of cells for transplantation |
US20030143737A1 (en) * | 1999-12-07 | 2003-07-31 | Monash University | Long-term cell-culture compositions and genetically modified animals derived therefrom |
WO2001066698A1 (en) | 2000-03-09 | 2001-09-13 | Cryo-Cell International, Inc. | Human cord blood as a source of neural tissue for repair of the brain and spinal cord |
GB0005856D0 (en) * | 2000-03-10 | 2000-05-03 | Reneuron Ltd | Genetic constructs |
US7250294B2 (en) | 2000-05-17 | 2007-07-31 | Geron Corporation | Screening small molecule drugs using neural cells differentiated from human embryonic stem cells |
US7049072B2 (en) | 2000-06-05 | 2006-05-23 | University Of South Florida | Gene expression analysis of pluri-differentiated mesenchymal progenitor cells and methods for diagnosing a leukemic disease state |
WO2001094541A2 (en) | 2000-06-05 | 2001-12-13 | University Of South Florida | Human mesenchymal progenitor cell |
WO2003029432A2 (en) | 2001-10-03 | 2003-04-10 | University Of South Florida | Human mesenchymal progenitor cell |
GB0125773D0 (en) | 2001-10-26 | 2001-12-19 | Reneuron Ltd | Constructs |
US20040185429A1 (en) * | 2002-12-09 | 2004-09-23 | Judith Kelleher-Andersson | Method for discovering neurogenic agents |
DE602005002430T2 (de) * | 2004-09-30 | 2008-06-19 | Reneuron Ltd., Guildford | Zelllinie |
-
2005
- 2005-09-23 DE DE602005002430T patent/DE602005002430T2/de active Active
- 2005-09-23 EP EP05255932A patent/EP1645626B1/de active Active
- 2005-09-23 DK DK05255932T patent/DK1645626T3/da active
- 2005-09-23 ES ES05255932T patent/ES2294650T3/es active Active
- 2005-09-23 AT AT05255932T patent/ATE373081T1/de active
- 2005-09-28 JP JP2005282179A patent/JP5036156B2/ja active Active
- 2005-09-28 CA CA2521421A patent/CA2521421C/en active Active
- 2005-09-29 US US11/238,702 patent/US7416888B2/en active Active
- 2005-09-30 AU AU2005218041A patent/AU2005218041B2/en not_active Ceased
- 2005-11-21 US US11/283,621 patent/US7419827B2/en active Active
-
2008
- 2008-01-28 US US12/020,874 patent/US7666672B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20080118479A1 (en) | 2008-05-22 |
US7416888B2 (en) | 2008-08-26 |
US20060104959A1 (en) | 2006-05-18 |
AU2005218041A1 (en) | 2006-04-13 |
AU2005218041B2 (en) | 2010-09-16 |
DE602005002430T2 (de) | 2008-06-19 |
ATE373081T1 (de) | 2007-09-15 |
US7419827B2 (en) | 2008-09-02 |
ES2294650T3 (es) | 2008-04-01 |
US20060067918A1 (en) | 2006-03-30 |
EP1645626A1 (de) | 2006-04-12 |
JP5036156B2 (ja) | 2012-09-26 |
CA2521421A1 (en) | 2006-03-30 |
EP1645626B1 (de) | 2007-09-12 |
US7666672B2 (en) | 2010-02-23 |
CA2521421C (en) | 2013-08-06 |
DK1645626T3 (da) | 2008-01-21 |
JP2006122045A (ja) | 2006-05-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |