ATE510917T1 - Desensibilisierte aspartokinase - Google Patents

Desensibilisierte aspartokinase

Info

Publication number
ATE510917T1
ATE510917T1 AT00917314T AT00917314T ATE510917T1 AT E510917 T1 ATE510917 T1 AT E510917T1 AT 00917314 T AT00917314 T AT 00917314T AT 00917314 T AT00917314 T AT 00917314T AT E510917 T1 ATE510917 T1 AT E510917T1
Authority
AT
Austria
Prior art keywords
amino acid
dna
coryneform bacterium
aspartokinase
lysine
Prior art date
Application number
AT00917314T
Other languages
English (en)
Inventor
Haruhiko Yokoi
Junko Ohnishi
Keiko Ochiai
Yoshiyuki Yonetani
Akio Ozaki
Original Assignee
Kyowa Hakko Bio Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Bio Co Ltd filed Critical Kyowa Hakko Bio Co Ltd
Application granted granted Critical
Publication of ATE510917T1 publication Critical patent/ATE510917T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
AT00917314T 1999-04-19 2000-04-14 Desensibilisierte aspartokinase ATE510917T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP11043799 1999-04-19
PCT/JP2000/002456 WO2000063388A1 (fr) 1999-04-19 2000-04-14 Nouvelle aspartokinase desensibilisee

Publications (1)

Publication Number Publication Date
ATE510917T1 true ATE510917T1 (de) 2011-06-15

Family

ID=14535714

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00917314T ATE510917T1 (de) 1999-04-19 2000-04-14 Desensibilisierte aspartokinase

Country Status (10)

Country Link
US (1) US6893848B1 (de)
EP (1) EP1172437B1 (de)
JP (1) JP4526710B2 (de)
KR (1) KR100671785B1 (de)
CN (1) CN100540668C (de)
AT (1) ATE510917T1 (de)
AU (1) AU3837400A (de)
HK (1) HK1042321B (de)
MX (1) MXPA01010413A (de)
WO (1) WO2000063388A1 (de)

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BR0211745A (pt) * 2001-08-06 2004-10-13 Degussa Bactérias corineformes que produzem compostos quìmicos ii
US7160711B2 (en) 2001-08-06 2007-01-09 Degussa Ag Coryneform bacteria which produce chemical compounds I
DE10210527A1 (de) 2002-03-09 2003-09-18 Degussa Allele des aceA-Gens aus coryneformen Bakterien
DE10239073A1 (de) * 2002-08-26 2004-03-11 Basf Ag Verfahren zur fermentativen Herstellung schwefelhaltiger Feinchemikalien
DE10359661A1 (de) * 2003-12-18 2005-07-28 Basf Ag Genvarianten die für Proteine aus dem Stoffwechselweg von Feinchemikalien codieren
DE102004011248A1 (de) * 2004-03-09 2005-09-22 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
CN101351551A (zh) 2005-11-29 2009-01-21 协和发酵工业株式会社 新型蛋白质和编码该蛋白质的dna
JP5592059B2 (ja) 2005-12-27 2014-09-17 協和発酵バイオ株式会社 Ｌ−グルタミンの製造法
EP1996714A1 (de) * 2006-03-09 2008-12-03 Basf Se VERFAHREN ZUR HERSTELLUNG VON ß-LYSIN
ES2592887T3 (es) * 2006-03-30 2016-12-02 Basf Se Procedimiento la producción de cadaverina
EP2386650B1 (de) * 2006-04-07 2013-07-03 Evonik Degussa GmbH Verfahren zur Herstellung von L-Lysin unter Verwendung des gap Promotors
DE102006032634A1 (de) 2006-07-13 2008-01-17 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
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JP5064396B2 (ja) 2006-09-01 2012-10-31 協和発酵バイオ株式会社 Ｌ‐グルタミンの製造法
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DE102008001874A1 (de) 2008-05-20 2009-11-26 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
CN102089437B (zh) 2008-07-09 2014-11-05 味之素株式会社 生产氨基羟基苯甲酸盐类化合物的方法
JP5170012B2 (ja) * 2009-06-26 2013-03-27 東レ株式会社 カダベリン発酵コリネ型細菌を用いたポリアミドの製造方法
US20120295317A1 (en) 2009-12-17 2012-11-22 Basf Se Processes and Recombinant Microorganisms for the Production of Cadaverine
KR101512432B1 (ko) 2010-06-15 2015-04-16 백광산업 주식회사 미생물을 이용한 아스파테이트 계열 아미노산의 생산방법
US9745608B2 (en) 2011-02-22 2017-08-29 Basf Se Processes and recombinant microorganisms for the production of cadaverine
DE102011118019A1 (de) 2011-06-28 2013-01-03 Evonik Degussa Gmbh Varianten des Promotors des für die Glyzerinaldehyd-3-phosphat-Dehydrogenase kodierenden gap-Gens
EP2857510A4 (de) 2012-05-29 2016-02-10 Ajinomoto Kk Verfahren zur herstellung von 3-acetylamino-4-hydroxybenzoesäure
DE102014208199A1 (de) 2014-04-30 2015-11-05 Evonik Degussa Gmbh Verfahren zur Produktion von L-Aminosäuren unter Verwendung eines alkaliphilen Bakteriums
EP2940143B1 (de) 2014-04-30 2020-02-05 Evonik Operations GmbH Verfahren zur Produktion von L-Aminosäuren unter Verwendung eines alkaliphilen Bakteriums
EP2940039A1 (de) 2014-04-30 2015-11-04 Evonik Degussa GmbH Verfahren zur Produktion von L-Aminosäuren in Corynebakterien unter Verwendung eines Glycin spaltenden Systems
EP2940144A1 (de) 2014-04-30 2015-11-04 Evonik Degussa GmbH Verfahren zur Produktion von L-Lysin unter Verwendung eines alkaliphilen Bakteriums
EP3456833A1 (de) 2017-09-18 2019-03-20 Evonik Degussa GmbH Methode zur fermentativen production von l-aminosäuren
EP3467099A1 (de) * 2017-10-05 2019-04-10 Evonik Degussa GmbH Verfahren zur fermentativen herstellung von l-aminosäuren
EP3498853A1 (de) 2017-12-14 2019-06-19 Evonik Degussa GmbH Verfahren zur fermentativen herstellung von l-lysin
EP3594355A1 (de) 2018-07-12 2020-01-15 Evonik Operations GmbH Verfahren zur fermentativen herstellung von l-lysin
EP3599282B1 (de) 2018-07-24 2021-03-17 Evonik Operations GmbH Verfahren zur fermentativen herstellung von l-lysin
RU2019128538A (ru) 2018-09-26 2021-03-11 Эвоник Оперейшенс ГмбХ Способ ферментативного получения l-лизина
EP3660158A1 (de) 2018-11-29 2020-06-03 Evonik Operations GmbH Verfahren zur fermentativen herstellung von l-lysin
EP3670525A1 (de) 2018-12-18 2020-06-24 Evonik Operations GmbH Verfahren zur fermentativen herstellung von l-lysin unter verwendung von c.-glutamicum-stämmen mit einem mutierten kup-transporter
US10829746B2 (en) 2019-01-23 2020-11-10 Evonik Operations Gmbh Method for the fermentative production of L-lysine
WO2021048353A1 (en) 2019-09-11 2021-03-18 Evonik Operations Gmbh Coryneform bacteria with a heterologous threonine transporter and their use in the production of l-threonine
WO2023041425A1 (en) 2021-09-20 2023-03-23 Evonik Operations Gmbh Method for the fermentative production of l-lysine using c. glutamicum strains expressing modified gluconate repressor proteins gntr1 and gntr2
WO2023222515A1 (en) 2022-05-18 2023-11-23 Evonik Operations Gmbh Biotechnological production of bisucaberins, desferrioxamines and analogs thereof
WO2023222505A1 (en) 2022-05-18 2023-11-23 Evonik Operations Gmbh Biotechnological production of monomers of bisucaberins, desferrioxamines and analogs thereof
WO2023222510A1 (en) 2022-05-18 2023-11-23 Evonik Operations Gmbh Biotechnological production of desferrioxamines and analogs thereof
CN117327677A (zh) * 2023-09-26 2024-01-02 江南大学 天冬氨酸激酶突变体及其应用

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JPS5886094A (ja) 1981-11-13 1983-05-23 Kyowa Hakko Kogyo Co Ltd 発酵法によるｌ−リジンノ製造法
JPS5828292A (ja) 1981-08-10 1983-02-19 Kyowa Hakko Kogyo Co Ltd 発酵法によるｌ−リジンの製造法
US5236831A (en) 1981-12-29 1993-08-17 Kiowa Hakko Kogyo Co., Ltd. Amino acid synthesis in corynebacteria using E. coli genes
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JPH0673318B2 (ja) 1986-09-02 1994-09-14 理化学研究所 マイクロ波導入装置
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US5096502A (en) 1990-12-03 1992-03-17 The Babcock & Wilcox Company Advanced water lance control system based on peak furnace wall emissivity
JPH0511959A (ja) 1991-07-04 1993-01-22 Matsushita Electric Ind Co Ltd マルチウインドウ制御装置
JP3473042B2 (ja) 1992-04-28 2003-12-02 味の素株式会社 変異型アスパルトキナーゼ遺伝子
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Also Published As

Publication number Publication date
US6893848B1 (en) 2005-05-17
WO2000063388A1 (fr) 2000-10-26
EP1172437A4 (de) 2002-08-14
MXPA01010413A (es) 2002-11-29
CN1355849A (zh) 2002-06-26
EP1172437B1 (de) 2011-05-25
CN100540668C (zh) 2009-09-16
JP4526710B2 (ja) 2010-08-18
KR100671785B1 (ko) 2007-01-19
HK1042321A1 (en) 2002-08-09
EP1172437A1 (de) 2002-01-16
KR20020006539A (ko) 2002-01-19
HK1042321B (zh) 2012-02-24
AU3837400A (en) 2000-11-02

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