BR0211745A - Bactérias corineformes que produzem compostos quìmicos ii - Google Patents

Bactérias corineformes que produzem compostos quìmicos ii

Info

Publication number
BR0211745A
BR0211745A BR0211745-2A BR0211745A BR0211745A BR 0211745 A BR0211745 A BR 0211745A BR 0211745 A BR0211745 A BR 0211745A BR 0211745 A BR0211745 A BR 0211745A
Authority
BR
Brazil
Prior art keywords
chemical compounds
gene
orf
allele
reading frame
Prior art date
Application number
BR0211745-2A
Other languages
English (en)
Inventor
Brigitte Bathe
Caroline Reynen
Bettina Moeckel
Georg Thierbach
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of BR0211745A publication Critical patent/BR0211745A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)

Abstract

"BACTéRIAS CORINEFORMES QUE PRODUZEM COMPOSTOS QUìMICOS II". A presente invenção refere-se a bactérias corineformes, que, em vez da cópia única de um quadro de leitura aberto (ORF), gene ou alelo naturalmente presentes no sítio (local) desejado particular, têm pelo menos duas cópias do referido quadro de leitura aberto (ORF), gene ou alelo, de preferência em uma disposição em tandem, e, opcionalmente, pelo menos uma terceira cópia do referido quadro de leitura aberto (ORF), gene ou alelo em questão, em um outro sítio genético, e processos para preparação dos compostos químicos por fermentação dessas bactérias.
BR0211745-2A 2001-08-06 2002-07-30 Bactérias corineformes que produzem compostos quìmicos ii BR0211745A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30987701P 2001-08-06 2001-08-06
PCT/EP2002/008465 WO2003014330A2 (en) 2001-08-06 2002-07-30 Coryneform bacteria which produce chemical compounds ii

Publications (1)

Publication Number Publication Date
BR0211745A true BR0211745A (pt) 2004-10-13

Family

ID=23200062

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0211745-2A BR0211745A (pt) 2001-08-06 2002-07-30 Bactérias corineformes que produzem compostos quìmicos ii

Country Status (12)

Country Link
US (2) US20040043458A1 (pt)
EP (1) EP1414986B1 (pt)
KR (1) KR100943834B1 (pt)
CN (2) CN100336901C (pt)
AT (1) ATE409752T1 (pt)
AU (1) AU2002355462A1 (pt)
BR (1) BR0211745A (pt)
CA (1) CA2456416A1 (pt)
DE (1) DE60229139D1 (pt)
DK (1) DK1414986T3 (pt)
ES (1) ES2314076T3 (pt)
WO (1) WO2003014330A2 (pt)

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RU2006125498A (ru) * 2003-12-18 2008-01-27 БАСФ Акциенгезельшафт (DE) Способы получения химического продукта тонкого органического синтеза путем ферментации
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EP1766002B1 (en) 2004-06-21 2015-11-18 Novozymes A/S Stably maintained multiple copies of at least two orf in the same orientation
DE102005013676A1 (de) 2005-03-24 2006-09-28 Degussa Ag Allele des zwf-Gens aus coryneformen Bakterien
DE102005023829A1 (de) 2005-05-24 2006-11-30 Degussa Ag Allele des opcA-Gens aus coryneformen Bakterien
WO2007037459A1 (en) * 2005-09-27 2007-04-05 Ajinomoto Co., Inc. An l-amino acid-producing bacterium and a method for producing l-amino acids
DE102005047596A1 (de) 2005-10-05 2007-04-12 Degussa Ag Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
DE102006032634A1 (de) 2006-07-13 2008-01-17 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
EP1881076A1 (en) * 2006-07-17 2008-01-23 Evonik Degussa GmbH Method for producing L-amino acids
DE102006048882A1 (de) * 2006-10-17 2008-04-24 Evonik Degussa Gmbh Allele des rel-Gens aus coryneformen Bakterien
DE102006050489A1 (de) * 2006-10-26 2008-04-30 Evonik Degussa Gmbh Allele des prpD1-Gens aus coryneformen Bakterien
DE102007005072A1 (de) 2007-02-01 2008-08-07 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von Cadaverin
DE102008001874A1 (de) 2008-05-20 2009-11-26 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
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DE102009030342A1 (de) 2009-06-25 2010-12-30 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von organisch chemischen Verbindungen
DE102010003419B4 (de) 2010-03-30 2019-09-12 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von L-Ornithin
EP2479279A1 (de) 2011-01-20 2012-07-25 Evonik Degussa GmbH Verfahren zur fermentativen Herstellung schwefelhaltiger Aminosäuren
DE102011006716A1 (de) 2011-04-04 2012-10-04 Evonik Degussa Gmbh Mikroorganismus und Verfahren zur fermentativen Herstellung einer organisch-chemischen Verbindung
DE102011118019A1 (de) 2011-06-28 2013-01-03 Evonik Degussa Gmbh Varianten des Promotors des für die Glyzerinaldehyd-3-phosphat-Dehydrogenase kodierenden gap-Gens
KR101335853B1 (ko) * 2011-12-01 2013-12-02 씨제이제일제당 (주) Ｌ-아미노산 및 리보플라빈을 동시에 생산하는 미생물 및 이를 이용한 ｌ-아미노산 및 리보플라빈을 생산하는 방법
EP2628792A1 (de) 2012-02-17 2013-08-21 Evonik Industries AG Zelle mit verringerter ppGppase-Aktivität
EP2631298A1 (en) 2012-02-22 2013-08-28 Evonik Industries AG Biotechnological method for producing butanol and butyric acid
DK2841568T3 (en) 2012-04-27 2018-05-22 Evonik Technochemie Gmbh FEEDBACK-RESISTANT ALFA ISOPROPYL MALATE SYNTHETAS
EP2674489A1 (en) 2012-06-15 2013-12-18 Evonik Industries AG Biotechnological 2-hydroxyisobutyric acid production
EP2700715B1 (de) 2012-08-20 2018-07-25 Evonik Degussa GmbH Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
EP2762571A1 (de) 2013-01-30 2014-08-06 Evonik Industries AG Mikroorganismus und Verfahren zur fermentativen Herstellung von Aminosäuren
ES2623161T3 (es) 2013-06-03 2017-07-10 Evonik Degussa Gmbh Procedimiento para la preparación de L-valina utilizando corinebacterias recombinantes que contienen el operón ilvBN inducible por propionato
CN103374540B (zh) * 2013-08-13 2015-04-22 廊坊梅花生物技术开发有限公司 谷氨酸棒杆菌及其应用
EP2940144A1 (de) 2014-04-30 2015-11-04 Evonik Degussa GmbH Verfahren zur Produktion von L-Lysin unter Verwendung eines alkaliphilen Bakteriums
DE102014208199A1 (de) 2014-04-30 2015-11-05 Evonik Degussa Gmbh Verfahren zur Produktion von L-Aminosäuren unter Verwendung eines alkaliphilen Bakteriums
ES2778037T3 (es) 2014-04-30 2020-08-07 Evonik Operations Gmbh Procedimiento para la producción de L-aminoácidos bajo empleo de una bacteria alcalífila
EP2940039A1 (de) 2014-04-30 2015-11-04 Evonik Degussa GmbH Verfahren zur Produktion von L-Aminosäuren in Corynebakterien unter Verwendung eines Glycin spaltenden Systems
US9988624B2 (en) 2015-12-07 2018-06-05 Zymergen Inc. Microbial strain improvement by a HTP genomic engineering platform
KR20180084756A (ko) 2015-12-07 2018-07-25 지머젠 인코포레이티드 코리네박테리움 글루타미컴으로부터의 프로모터
US11208649B2 (en) 2015-12-07 2021-12-28 Zymergen Inc. HTP genomic engineering platform
CN105734004B (zh) * 2016-03-02 2020-06-19 廊坊梅花生物技术开发有限公司 重组菌株及其制备方法、应用
JP2019519241A (ja) 2016-06-30 2019-07-11 ザイマージェン インコーポレイテッド グルコース透過酵素ライブラリーを生成するための方法およびその使用
JP2019519242A (ja) 2016-06-30 2019-07-11 ザイマージェン インコーポレイテッド 細菌ヘモグロビンライブラリーを生成するための方法およびその使用
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CN110869504A (zh) 2017-06-07 2020-03-06 齐默尔根公司 来自谷氨酸棒状杆菌的启动子及其在调节辅助基因表达中的用途
EP3415622A1 (en) 2017-06-14 2018-12-19 Evonik Degussa GmbH Method for production of fine chemicals using a corynebacterium secreting modified alpha-1,6-glucosidases
WO2020051420A1 (en) 2018-09-07 2020-03-12 Archer Daniels Midland Company Engineered strains of corynebacteria
WO2021048353A1 (en) * 2019-09-11 2021-03-18 Evonik Operations Gmbh Coryneform bacteria with a heterologous threonine transporter and their use in the production of l-threonine

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HU222503B1 (hu) * 1995-06-07 2003-07-28 Ajinomoto Co., Inc. Eljárás L-lizin termelésére
US7267967B1 (en) * 1997-10-04 2007-09-11 Forschungszentrum Julich Gmbh Nucleic acid encoding pyruvate carboxylase from coryneform glutamicum
DE19931317A1 (de) * 1999-07-07 2001-01-11 Degussa L-Lysin produzierende coryneforme Bakterien und Verfahren zur Herstellung von L-Lysin
JP4526710B2 (ja) * 1999-04-19 2010-08-18 協和発酵バイオ株式会社 新規な脱感作型アスパルトキナーゼ
US20030049804A1 (en) * 1999-06-25 2003-03-13 Markus Pompejus Corynebacterium glutamicum genes encoding metabolic pathway proteins
DE19950409A1 (de) * 1999-10-20 2001-04-26 Degussa Neue für das pck-Gen codierende Nukleotidsequenzen
DE19959328A1 (de) * 1999-12-09 2001-06-13 Degussa Neue für das zwa1-Gen codierende Nukleotidsequenzen
JP4623825B2 (ja) * 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド
CN1289781A (zh) * 2000-08-30 2001-04-04 北京东方龙基生物技术有限公司 截短型人胰岛素样生长因子－ⅰ及其制备方法
ATE321862T1 (de) * 2000-09-12 2006-04-15 Degussa Coryneforme bakterien transformiert mit dem pknd- gen kodierenden nukleotidsequenzen und deren verwendung zur herstellung von l -aminosäuren

Also Published As

Publication number Publication date
WO2003014330A3 (en) 2003-12-18
ES2314076T3 (es) 2009-03-16
CN101126075A (zh) 2008-02-20
AU2002355462A1 (en) 2003-02-24
DK1414986T3 (da) 2009-01-19
US20040043458A1 (en) 2004-03-04
CN101126075B (zh) 2012-05-09
EP1414986A2 (en) 2004-05-06
ATE409752T1 (de) 2008-10-15
DE60229139D1 (de) 2008-11-13
KR100943834B1 (ko) 2010-02-24
WO2003014330A2 (en) 2003-02-20
US20100255544A1 (en) 2010-10-07
KR20040041576A (ko) 2004-05-17
EP1414986B1 (en) 2008-10-01
CA2456416A1 (en) 2003-02-20
CN100336901C (zh) 2007-09-12
CN1541274A (zh) 2004-10-27

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Legal Events

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25D Requested change of name of applicant approved

Owner name: DEGUSSA GMBH (DE)

Free format text: NOME ALTERADO DE: DEGUSSA AG

B25D Requested change of name of applicant approved

Owner name: EVONIK DEGUSSA GMBH (DE)

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B25G Requested change of headquarter approved

Owner name: EVONIK DEGUSSA GMBH (DE)

Free format text: ENDERECO ALTERADO CONFORME SOLICITADO NA PETICAO NO 020100037415/RJ DE 29/04/2010.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: A CLASSIFICACAO ANTERIOR ERA: C12P 13/08

Ipc: C12N 1/21 (2006.01), C12P 13/08 (2006.01), C12R 1/

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

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