ATE409752T1 - Coryneforme bakterien, die chemische substanzen bilden ii - Google Patents

Coryneforme bakterien, die chemische substanzen bilden ii

Info

Publication number
ATE409752T1
ATE409752T1 AT02751164T AT02751164T ATE409752T1 AT E409752 T1 ATE409752 T1 AT E409752T1 AT 02751164 T AT02751164 T AT 02751164T AT 02751164 T AT02751164 T AT 02751164T AT E409752 T1 ATE409752 T1 AT E409752T1
Authority
AT
Austria
Prior art keywords
gene
coryneform bacteria
orf
allele
reading frame
Prior art date
Application number
AT02751164T
Other languages
English (en)
Inventor
Brigitte Bathe
Caroline Reynen
Bettina Moeckel
Georg Thierbach
Original Assignee
Evonik Degussa Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Degussa Gmbh filed Critical Evonik Degussa Gmbh
Application granted granted Critical
Publication of ATE409752T1 publication Critical patent/ATE409752T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
AT02751164T 2001-08-06 2002-07-30 Coryneforme bakterien, die chemische substanzen bilden ii ATE409752T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30987701P 2001-08-06 2001-08-06

Publications (1)

Publication Number Publication Date
ATE409752T1 true ATE409752T1 (de) 2008-10-15

Family

ID=23200062

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02751164T ATE409752T1 (de) 2001-08-06 2002-07-30 Coryneforme bakterien, die chemische substanzen bilden ii

Country Status (12)

Country Link
US (2) US20040043458A1 (de)
EP (1) EP1414986B1 (de)
KR (1) KR100943834B1 (de)
CN (2) CN101126075B (de)
AT (1) ATE409752T1 (de)
AU (1) AU2002355462A1 (de)
BR (1) BR0211745A (de)
CA (1) CA2456416A1 (de)
DE (1) DE60229139D1 (de)
DK (1) DK1414986T3 (de)
ES (1) ES2314076T3 (de)
WO (1) WO2003014330A2 (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
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US7160711B2 (en) * 2001-08-06 2007-01-09 Degussa Ag Coryneform bacteria which produce chemical compounds I
US6844176B1 (en) 2001-10-16 2005-01-18 Degussa Ag Alleles of the lysC gene from corynebacteria
AU2004320598A1 (en) * 2003-12-18 2005-12-22 Basf Aktiengesellschaft Methods for the preparation of a fine chemical by fermentation
AU2004299728A1 (en) * 2003-12-18 2005-06-30 Basf Aktiengesellschaft Methods for the preparation of a fine chemical by fermentation
KR100786987B1 (ko) 2004-01-30 2007-12-18 아지노모토 가부시키가이샤 Ｌ-아미노산 생산 미생물 및 ｌ-아미노산 생산 방법
EP1766002B1 (de) 2004-06-21 2015-11-18 Novozymes A/S Mehrere kopien wenigstens zweier offener leserrahmen stabil erhalten in gleicher orientierung
DE102005013676A1 (de) 2005-03-24 2006-09-28 Degussa Ag Allele des zwf-Gens aus coryneformen Bakterien
DE102005023829A1 (de) 2005-05-24 2006-11-30 Degussa Ag Allele des opcA-Gens aus coryneformen Bakterien
WO2007037459A1 (en) * 2005-09-27 2007-04-05 Ajinomoto Co., Inc. An l-amino acid-producing bacterium and a method for producing l-amino acids
DE102005047596A1 (de) 2005-10-05 2007-04-12 Degussa Ag Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
DE102006032634A1 (de) 2006-07-13 2008-01-17 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
EP1881076A1 (de) * 2006-07-17 2008-01-23 Evonik Degussa GmbH Verfahren zur Herstellung von L-Aminosäuren
DE102006048882A1 (de) * 2006-10-17 2008-04-24 Evonik Degussa Gmbh Allele des rel-Gens aus coryneformen Bakterien
DE102006050489A1 (de) * 2006-10-26 2008-04-30 Evonik Degussa Gmbh Allele des prpD1-Gens aus coryneformen Bakterien
DE102007005072A1 (de) 2007-02-01 2008-08-07 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von Cadaverin
DE102008001874A1 (de) 2008-05-20 2009-11-26 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
DE102009030342A1 (de) 2009-06-25 2010-12-30 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von organisch chemischen Verbindungen
DE102010003419B4 (de) 2010-03-30 2019-09-12 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von L-Ornithin
EP2479279A1 (de) 2011-01-20 2012-07-25 Evonik Degussa GmbH Verfahren zur fermentativen Herstellung schwefelhaltiger Aminosäuren
DE102011006716A1 (de) 2011-04-04 2012-10-04 Evonik Degussa Gmbh Mikroorganismus und Verfahren zur fermentativen Herstellung einer organisch-chemischen Verbindung
DE102011118019A1 (de) 2011-06-28 2013-01-03 Evonik Degussa Gmbh Varianten des Promotors des für die Glyzerinaldehyd-3-phosphat-Dehydrogenase kodierenden gap-Gens
KR101335853B1 (ko) * 2011-12-01 2013-12-02 씨제이제일제당 (주) Ｌ-아미노산 및 리보플라빈을 동시에 생산하는 미생물 및 이를 이용한 ｌ-아미노산 및 리보플라빈을 생산하는 방법
EP2628792A1 (de) 2012-02-17 2013-08-21 Evonik Industries AG Zelle mit verringerter ppGppase-Aktivität
EP2631298A1 (de) 2012-02-22 2013-08-28 Evonik Industries AG Biotechnologisches Verfahren zur Herstellung von Butanol und Buttersäure
CN104302765B (zh) 2012-04-27 2018-09-11 赢创工业化学有限公司 反馈抗性α-异丙基苹果酸合酶
EP2674489A1 (de) 2012-06-15 2013-12-18 Evonik Industries AG Biotechnologische Herstellung von 2-hydroxyisobuttersäure
PL2700715T3 (pl) 2012-08-20 2019-03-29 Evonik Degussa Gmbh Sposób fermentacyjnego wytwarzania L-aminokwasów z zastosowaniem ulepszonych szczepów z rodziny Enterobacteriaceae
EP2762571A1 (de) 2013-01-30 2014-08-06 Evonik Industries AG Mikroorganismus und Verfahren zur fermentativen Herstellung von Aminosäuren
DK2811028T3 (en) 2013-06-03 2017-05-01 Evonik Degussa Gmbh Process for Preparation of L-Valine Using Recombinant Coryn Bacteria Containing the Propionate Inducible IlvBN Operon
CN103374540B (zh) * 2013-08-13 2015-04-22 廊坊梅花生物技术开发有限公司 谷氨酸棒杆菌及其应用
EP2940039A1 (de) 2014-04-30 2015-11-04 Evonik Degussa GmbH Verfahren zur Produktion von L-Aminosäuren in Corynebakterien unter Verwendung eines Glycin spaltenden Systems
EP2940143B1 (de) 2014-04-30 2020-02-05 Evonik Operations GmbH Verfahren zur Produktion von L-Aminosäuren unter Verwendung eines alkaliphilen Bakteriums
EP2940144A1 (de) 2014-04-30 2015-11-04 Evonik Degussa GmbH Verfahren zur Produktion von L-Lysin unter Verwendung eines alkaliphilen Bakteriums
DE102014208199A1 (de) 2014-04-30 2015-11-05 Evonik Degussa Gmbh Verfahren zur Produktion von L-Aminosäuren unter Verwendung eines alkaliphilen Bakteriums
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
JP6821598B2 (ja) 2015-12-07 2021-01-27 ザイマージェン インコーポレイテッド Ｃｏｒｙｎｅｂａｃｔｅｒｉｕｍ ｇｌｕｔａｍｉｃｕｍ由来のプロモーター
US11208649B2 (en) 2015-12-07 2021-12-28 Zymergen Inc. HTP genomic engineering platform
US9988624B2 (en) 2015-12-07 2018-06-05 Zymergen Inc. Microbial strain improvement by a HTP genomic engineering platform
CN105734004B (zh) * 2016-03-02 2020-06-19 廊坊梅花生物技术开发有限公司 重组菌株及其制备方法、应用
JP2019519241A (ja) 2016-06-30 2019-07-11 ザイマージェン インコーポレイテッド グルコース透過酵素ライブラリーを生成するための方法およびその使用
EP3478833A4 (de) 2016-06-30 2019-10-02 Zymergen, Inc. Verfahren zum erzeugen einer bakteriellen hämoglobin-bibliothek und deren verwendung
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CA3064777A1 (en) 2017-06-07 2018-12-13 Zach Serber Promoters from corynebacterium glutamicum and uses thereof in regulating ancillary gene expression
EP3415622A1 (de) 2017-06-14 2018-12-19 Evonik Degussa GmbH Verfahren zur herstellung von feinchemikalien mittels eines corynebakteriums, welches modifizierte alpha-1,6-glucosidasen sezerniert
US20240254526A1 (en) 2018-09-07 2024-08-01 Archer Daniels Midland Company Engineered strains of corynebacteria
WO2021048353A1 (en) * 2019-09-11 2021-03-18 Evonik Operations Gmbh Coryneform bacteria with a heterologous threonine transporter and their use in the production of l-threonine
CN113201514B (zh) * 2020-10-16 2022-09-06 中国科学院天津工业生物技术研究所 具有天冬氨酸激酶活性的多肽及其在生产氨基酸中的应用
CN115786219B (zh) * 2022-08-15 2026-02-24 江南大学 一种高产四氢嘧啶的重组谷氨酸棒杆菌及其应用

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SK285013B6 (sk) * 1995-06-07 2006-04-06 Ajinomoto Co., Inc. Rekombinantná DNA, autonómne replikovateľná v bunkách koryneformných baktérií, koryneformná baktéria a spôsob výroby L-lyzínu
WO1999018228A2 (de) * 1997-10-04 1999-04-15 Forschungszentrum Jülich GmbH Verfahren zur mikrobiellen herstellung von aminosäuren der aspartat- und/oder glutamatfamilie und im verfahren einsetzbare mittel
DE19931317A1 (de) * 1999-07-07 2001-01-11 Degussa L-Lysin produzierende coryneforme Bakterien und Verfahren zur Herstellung von L-Lysin
US6893848B1 (en) * 1999-04-19 2005-05-17 Kyowa Hakko Kogyo Co., Ltd. Desensitized aspartokinase
US20030049804A1 (en) * 1999-06-25 2003-03-13 Markus Pompejus Corynebacterium glutamicum genes encoding metabolic pathway proteins
DE19950409A1 (de) * 1999-10-20 2001-04-26 Degussa Neue für das pck-Gen codierende Nukleotidsequenzen
DE19959328A1 (de) * 1999-12-09 2001-06-13 Degussa Neue für das zwa1-Gen codierende Nukleotidsequenzen
JP4623825B2 (ja) * 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド
CN1289781A (zh) * 2000-08-30 2001-04-04 北京东方龙基生物技术有限公司 截短型人胰岛素样生长因子－ⅰ及其制备方法
WO2002022632A2 (en) * 2000-09-12 2002-03-21 Degussa Ag Nucleotide sequences coding for the pknd gene

Also Published As

Publication number Publication date
KR100943834B1 (ko) 2010-02-24
AU2002355462A1 (en) 2003-02-24
US20040043458A1 (en) 2004-03-04
WO2003014330A3 (en) 2003-12-18
ES2314076T3 (es) 2009-03-16
EP1414986A2 (de) 2004-05-06
WO2003014330A2 (en) 2003-02-20
DK1414986T3 (da) 2009-01-19
EP1414986B1 (de) 2008-10-01
CN100336901C (zh) 2007-09-12
KR20040041576A (ko) 2004-05-17
CN101126075B (zh) 2012-05-09
CN101126075A (zh) 2008-02-20
CN1541274A (zh) 2004-10-27
DE60229139D1 (de) 2008-11-13
US20100255544A1 (en) 2010-10-07
BR0211745A (pt) 2004-10-13
CA2456416A1 (en) 2003-02-20

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