DK1360312T3 - Fremgangsmåde til fremstilling af L-threonin - Google Patents

Fremgangsmåde til fremstilling af L-threonin

Info

Publication number
DK1360312T3
DK1360312T3 DK02701741T DK02701741T DK1360312T3 DK 1360312 T3 DK1360312 T3 DK 1360312T3 DK 02701741 T DK02701741 T DK 02701741T DK 02701741 T DK02701741 T DK 02701741T DK 1360312 T3 DK1360312 T3 DK 1360312T3
Authority
DK
Denmark
Prior art keywords
threonine
preparation
microorganism
carboxylase gene
threonine operon
Prior art date
Application number
DK02701741T
Other languages
English (en)
Inventor
Kap-Soo - Samsung Apt Noh
Dai-Chul - Hwanggolmaeul Kim
Yeong-Chul - Hanyang Apt Kim
Jae-Yong Park
Jin-Ho Lee
Seung-Han Ok
Original Assignee
Cheil Jedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cheil Jedang Corp filed Critical Cheil Jedang Corp
Application granted granted Critical
Publication of DK1360312T3 publication Critical patent/DK1360312T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK02701741T 2001-02-13 2002-02-14 Fremgangsmåde til fremstilling af L-threonin DK1360312T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR10-2001-0006976A KR100397423B1 (ko) 2001-02-13 2001-02-13 Ｌ-쓰레오닌의 제조방법

Publications (1)

Publication Number Publication Date
DK1360312T3 true DK1360312T3 (da) 2006-04-10

Family

ID=36143610

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02701741T DK1360312T3 (da) 2001-02-13 2002-02-14 Fremgangsmåde til fremstilling af L-threonin

Country Status (10)

Country Link
US (1) US7011961B2 (da)
EP (1) EP1360312B1 (da)
JP (1) JP3930431B2 (da)
KR (1) KR100397423B1 (da)
CN (1) CN1252278C (da)
AT (1) ATE311468T1 (da)
DE (1) DE60207685T2 (da)
DK (1) DK1360312T3 (da)
ES (1) ES2252422T3 (da)
WO (1) WO2002064808A1 (da)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100426807B1 (ko) * 2001-06-19 2004-04-13 씨제이 주식회사 엘-쓰레오닌 생산 미생물 및 이를 이용한 엘-쓰레오닌 제조방법
KR100426808B1 (ko) * 2001-06-19 2004-04-13 씨제이 주식회사 엘-쓰레오닌 생산 미생물 및 이를 이용한 엘-쓰레오닌 제조방법
DE60225288T2 (de) * 2001-07-18 2009-03-26 Evonik Degussa Gmbh Verfahren zur herstellung von l-aminosäuren unter verwendung von stämmen aus der familie der enterobacteriaceae die ein attenuiertes ugpb-gen enthalten
US7378267B1 (en) 2002-05-16 2008-05-27 Cheil Jedang Corporation Method for L-threonine production
KR100505797B1 (ko) * 2002-10-11 2005-08-04 씨제이 주식회사 염색체 상의 ｆａｄＲ 유전자가 불활성화된 Ｌ-쓰레오닌 생성 변이 미생물과 이를 이용한 Ｌ-쓰레오닌의 제조방법
DE10303571A1 (de) 2003-01-30 2004-08-12 Degussa Ag Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
KR100498971B1 (ko) * 2003-04-04 2005-07-04 씨제이 주식회사 염색체 내 ｔｄｃＢＣ 및 ｐｃｋＡ 유전자가 불활성화된 미생물 및 이를 이용하여 Ｌ-쓰레오닌을 제조하는 방법
DE10316109A1 (de) 2003-04-09 2004-10-21 Degussa Ag Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
KR100478468B1 (ko) 2003-09-06 2005-03-23 씨제이 주식회사 Ｌ―쓰레오닌의 제조방법
KR100576342B1 (ko) * 2004-02-05 2006-05-03 씨제이 주식회사 ｇａｌＲ 유전자가 불활성화된 Ｌ-쓰레오닌 생성 미생물,그를 제조하는 방법 및 상기 미생물을 이용한Ｌ-쓰레오닌의 제조방법
KR100608085B1 (ko) 2004-02-05 2006-08-02 씨제이 주식회사 ｔｙｒＲ 유전자가 불활성화된 Ｌ-쓰레오닌 생성 미생물,그를 제조하는 방법 및 상기 미생물을 이용한Ｌ-쓰레오닌의 제조방법
DE102004005836A1 (de) 2004-02-06 2005-09-15 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
KR100576344B1 (ko) * 2004-08-21 2006-05-03 씨제이 주식회사 프롤린에 의한 길항조절이 해제된 글루타밀 키나제변이체를 코딩하는 핵산, 그를 포함하는 벡터 및 숙주세포및 상기 숙주세포를 이용한 ｌ－트레오닌의 생산방법
KR100596372B1 (ko) * 2004-12-06 2006-07-04 씨제이 주식회사 염색체 상의 ｌｙｓＲ유전자가 불활성화된 Ｌ-쓰레오닌생성 미생물, 그를 제조하는 방법 및 상기 미생물을이용한 Ｌ-쓰레오닌의 제조방법
DE102005018835A1 (de) 2005-04-22 2006-11-02 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung verbesserter Stämme der Familie Enterobacteriaceae
DE102007051024A1 (de) 2007-03-05 2008-09-11 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
KR100858913B1 (ko) 2007-03-09 2008-09-17 한국과학기술원 부위특이적 변이에 의해 제조된 고수율의 ｌ－쓰레오닌생산균주 및 이를 이용한 ｌ－쓰레오닌의 제조방법
EP1975241A1 (de) 2007-03-29 2008-10-01 Evonik Degussa GmbH Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
DE102007044134A1 (de) 2007-09-15 2009-03-19 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
DE102007052270A1 (de) 2007-11-02 2009-05-07 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
EP2060636A1 (de) 2007-11-14 2009-05-20 Evonik Degussa GmbH Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
EP2098597A1 (de) 2008-03-04 2009-09-09 Evonik Degussa GmbH Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
DE102008002309A1 (de) 2008-06-09 2009-12-10 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
DE102008044768A1 (de) 2008-08-28 2010-03-04 Evonik Degussa Gmbh Verfahren zur Herstellung von organisch-chemischen Verbindungen unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
EP2267145A1 (de) 2009-06-24 2010-12-29 Evonik Degussa GmbH Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
EP2363489A1 (en) 2010-03-03 2011-09-07 Technische Universität Hamburg-Harburg Enzyme Aspartokinase III having a reduced L-lysine feedback inhibition
EP2374873A1 (en) 2010-04-08 2011-10-12 Technische Universität Hamburg-Harburg Modified aspartate kinase from corynebacterium and its application for amino acid production
EP2495317A1 (en) 2011-03-01 2012-09-05 Technische Universität Hamburg-Harburg Modified phosphoenolpyruvate carboxylase from Corynebacterium glutamicum and uses thereof
RU2697005C2 (ru) * 2013-10-11 2019-08-08 СиДжей ЧЕИЛДЗЕДАНГ КОРП. Способ получения l-аминокислот
EP2860256B1 (en) * 2013-10-11 2017-03-08 CJ Cheiljedang Corporation Method of producing l-amino acids
KR101518860B1 (ko) * 2013-10-11 2015-05-12 씨제이제일제당 (주) L-아미노산의 생산 방법
EP3608409A1 (en) 2018-08-09 2020-02-12 Evonik Operations GmbH Process for preparing l amino acids using improved strains of the enterobacteriaceae family
CN111363757B (zh) * 2020-01-19 2022-08-09 江南大学 一种温度开关系统及其在提高氨基酸产量中的应用
CN116622597A (zh) * 2022-02-10 2023-08-22 廊坊梅花生物技术开发有限公司 高产苏氨酸工程菌的构建方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5236831A (en) * 1981-12-29 1993-08-17 Kiowa Hakko Kogyo Co., Ltd. Amino acid synthesis in corynebacteria using E. coli genes
WO1990004636A1 (en) * 1988-10-25 1990-05-03 Vsesojuzny Nauchno-Issledovatelsky Institut Genetiki I Selektsii Promyshlennykh Mikroorganizmov (Vniigenetika) Strain of bacteria escherichia coli, producer of l-threonine
JPH0632626B2 (ja) 1989-02-20 1994-05-02 東レ株式会社 発酵法によるｌ―スレオニンの製造法
KR920009598B1 (ko) 1990-10-11 1992-10-21 주식회사삼성전자 풀림방지용 체결기구
KR960009321B1 (en) 1992-12-17 1996-07-18 Cheil Foods & Chem Making method of l-threonin by recombinant microorganism
US5876983A (en) * 1993-08-24 1999-03-02 Ajinomoto Co., Inc. Mutant phosphoenolpyruvate carboxylase, its gene, and production method of amino acid
US5998178A (en) * 1994-05-30 1999-12-07 Ajinomoto Co., Ltd. L-isoleucine-producing bacterium and method for preparing L-isoleucine through fermentation
US5939307A (en) * 1996-07-30 1999-08-17 The Archer-Daniels-Midland Company Strains of Escherichia coli, methods of preparing the same and use thereof in fermentation processes for l-threonine production
JP4075087B2 (ja) * 1996-12-05 2008-04-16 味の素株式会社 Ｌ−リジンの製造法
AU1206801A (en) 1999-10-13 2001-04-23 University Of Georgia Research Foundation, Inc., The High yield protein expression system and methods
JP4265093B2 (ja) * 2000-08-11 2009-05-20 味の素株式会社 スレオニン及びイソロイシンの製造法

Also Published As

Publication number Publication date
KR100397423B1 (ko) 2003-09-13
EP1360312A4 (en) 2005-01-05
DE60207685T2 (de) 2006-07-13
CN1252278C (zh) 2006-04-19
US7011961B2 (en) 2006-03-14
CN1457365A (zh) 2003-11-19
ATE311468T1 (de) 2005-12-15
DE60207685D1 (de) 2006-01-05
EP1360312A1 (en) 2003-11-12
WO2002064808A1 (en) 2002-08-22
ES2252422T3 (es) 2006-05-16
JP2004518439A (ja) 2004-06-24
KR20020066662A (ko) 2002-08-21
JP3930431B2 (ja) 2007-06-13
US20030153057A1 (en) 2003-08-14
EP1360312B1 (en) 2005-11-30

Similar Documents

Publication Publication Date Title
DK1360312T3 (da) Fremgangsmåde til fremstilling af L-threonin
AU2001283963A1 (en) Polysiloxane polymers, method for their production and the use thereof
DK0966447T3 (da) Anvendelige små molekyler til behandling af betændelsessygdomme
HUP0303738A2 (hu) Új peszticid toxinok
ATE346156T1 (de) Umkehrtransfektionsverfahren
MX342777B (es) Inhibidores tnfa para usarse en el tratamiento de trastornos relacionados con tnfa.
BR0307432B1 (pt) difluormetiltiazolilcarboxanilidas
AU2001258316A1 (en) Process for the fermentative preparation of l-threonine
DE60323340D1 (de) Verfahren zur herstellung interferierender rna-moleküle in säugetierzellen und therapeutische anwendungen solcher moleküle
DE602007013447D1 (de) Glutaminsäure in hoher ausbeute produzierender mikroorganismus und verfahren zur produktion von glutaminsäure damit
ATE269105T1 (de) Mucoadhäsive polymere, deren verwendung sowie deren herstellungsverfahren
FR2813314B1 (fr) Procede de mutagenese dirigee massive
DE602006005207D1 (de) Mikroorganismen des Genus Corynebakteriums mit Resistenz gegen Kanamycin und erhöhter L-Lysin-Produktivität und Verfahren zur Herstellung von L-Lysin damit
AU2003224490A1 (en) The microorganism of which the fadr gene was knocked out on the chromosome and a process for producing l-threonine by fermentation with the same mutant
DE50102671D1 (de) Diethyloctandioldicarbamate und diethyloctandioldiallophanate, verfahren zu ihrer herstellung und ihre verwendung
UA83203C2 (uk) Тіазол-(бі)циклоалкілкарбоксаніліди, засіб на їх основі та застосування для боротьби з небажаними мікроорганізмами
ATE403663T1 (de) Nukleinsäureamplifikation mit duplexzwischenprodukten
ATE353959T1 (de) Allele des siga gens aus coryneformen bakterien
ZA200604654B (en) Pyrazolopyrimidines
ES2185196T3 (es) Un procedimiento para la preparacion de tetraazamacrociclos.
DK1458869T3 (da) Alleler af glucokinasegenet af coryneforme bakterier
WO2003027290A1 (fr) Procede pour conferer ou reguler la fertilite d'un cytoplasme a sterilite male de riz bt au moyen d'un gene de restauration de la fertilite, et procede d'estimation de la presence d'un gene de restauration de la fertilite
PT1591520T (pt) Microrganismo produtor de l-treonina possuindo um gene tyr inativado, método de produção do mesmo e método de produção de l-treonina utilizando o microrganismo
RS20050887A (en) Nutritional composition and method of inhibiting smooth muscle cell contraction thereof
DK1352050T3 (da) Mikrobiologisk fremgangsmåde til fremstilling af amider