ATE508202T1 - Verfahren zur diagnose von brustkrebs - Google Patents

Verfahren zur diagnose von brustkrebs

Info

Publication number
ATE508202T1
ATE508202T1 AT04773526T AT04773526T ATE508202T1 AT E508202 T1 ATE508202 T1 AT E508202T1 AT 04773526 T AT04773526 T AT 04773526T AT 04773526 T AT04773526 T AT 04773526T AT E508202 T1 ATE508202 T1 AT E508202T1
Authority
AT
Austria
Prior art keywords
breast cancer
brc
cells
methods
discriminates
Prior art date
Application number
AT04773526T
Other languages
German (de)
English (en)
Inventor
Yusuke Nakamura
Toyomasa Katagiri
Shuichi Nakatsuru
Original Assignee
Oncotherapy Science Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Oncotherapy Science Inc filed Critical Oncotherapy Science Inc
Application granted granted Critical
Publication of ATE508202T1 publication Critical patent/ATE508202T1/de

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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57515Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/04Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT04773526T 2003-09-24 2004-09-24 Verfahren zur diagnose von brustkrebs ATE508202T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50557103P 2003-09-24 2003-09-24
PCT/JP2004/014438 WO2005028676A2 (en) 2003-09-24 2004-09-24 Method of diagnosing breast cancer

Publications (1)

Publication Number Publication Date
ATE508202T1 true ATE508202T1 (de) 2011-05-15

Family

ID=34375580

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04773526T ATE508202T1 (de) 2003-09-24 2004-09-24 Verfahren zur diagnose von brustkrebs

Country Status (9)

Country Link
US (3) US7531300B2 (enExample)
EP (2) EP1668354A2 (enExample)
JP (3) JP4579246B2 (enExample)
CN (2) CN1898563B (enExample)
AT (1) ATE508202T1 (enExample)
DE (1) DE602004032556D1 (enExample)
ES (1) ES2365732T3 (enExample)
TW (2) TW200512298A (enExample)
WO (2) WO2005029067A2 (enExample)

Families Citing this family (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ547955A (en) * 2003-12-05 2010-03-26 Erasmus Mc Predicting response and outcome of metastatic breast cancer anti-estrogen therapy
FR2875512B1 (fr) * 2004-09-17 2011-02-04 Diagnogene S A Biopuce de diagnostic du caractere metastatique ou localise d'une tumeur mammaire, procede et kit d'utilisation
EP1854473A1 (en) * 2005-03-03 2007-11-14 Takeda Pharmaceutical Company Limited Preventive/therapeutic agent for cancer
EP1863530B1 (en) * 2005-03-11 2010-07-14 Oncotherapy Science, Inc. Methods for damaging cells using effector functions of anti-gfra1 antibodies
EP1915462A2 (en) * 2005-07-28 2008-04-30 Oncotherapy Science, Inc. Cancer related gene rasgef1a
DE602006021315D1 (de) * 2005-07-29 2011-05-26 Oncotherapy Science Inc Gen und polypeptid in zusammenhang mit brustkrebs
JP2007037421A (ja) * 2005-08-01 2007-02-15 Osaka Univ 大腸癌リンパ節転移の有無を予測するための遺伝子セット
EP1946118A4 (en) * 2005-11-10 2009-01-21 Aurelium Biopharma Inc TISSUE DIAGNOSIS OF BREAST CANCER
WO2007061770A2 (en) * 2005-11-17 2007-05-31 University Of Maryland Method and system for analysis of time-series molecular quantities
JPWO2007088971A1 (ja) * 2006-02-03 2009-06-25 メッセンジャー・スケープ株式会社 がん予後判定に利用できる遺伝子群
CN101415440A (zh) 2006-02-10 2009-04-22 肿瘤疗法科学股份有限公司 治疗肺癌的方法
US20080108065A1 (en) * 2006-04-28 2008-05-08 Indra Poola Systems and diagnostic methods for breast cancer using mmp-1 markers
KR20090064378A (ko) 2006-08-10 2009-06-18 온코세라피 사이언스 가부시키가이샤 유방암 관련 유전자 및 폴리펩티드
EP3135773A1 (en) * 2006-09-27 2017-03-01 Sividon Diagnostics GmbH Methods for breast cancer prognosis
EP2128621A4 (en) * 2007-02-01 2011-05-18 Oriental Yeast Co Ltd METHOD FOR DETECTING BREAST CANCER CELLS
US8105796B2 (en) 2007-02-15 2012-01-31 Universita' Degli Studi Di Torino Regulation of expression of PI3Kβ protein in tumors
TW200908998A (en) * 2007-06-27 2009-03-01 Oncotherapy Science Inc Compositions and methods of treating cancer
PT2186889E (pt) * 2007-08-20 2015-06-17 Oncotherapy Science Inc Péptido cdca1 e agente farmacêutico que o compreende
MX2010002002A (es) 2007-08-20 2010-03-11 Oncotherapy Science Inc Peptido foxm1 y agente medicinal que lo contiene.
WO2009045179A1 (en) * 2007-10-04 2009-04-09 Agency For Science, Technology And Research (A*Star) Taz/wwtr1 for diagnosis and treatment of cancer
US8088715B2 (en) * 2007-11-13 2012-01-03 Ikonisys, Inc. Detection of circulating tumor cells in peripheral blood with an automated scanning fluorescence microscope
WO2009089548A2 (en) * 2008-01-11 2009-07-16 H. Lee Moffitt Cancer & Research Institute, Inc. Malignancy-risk signature from histologically normal breast tissue
WO2009116860A1 (en) * 2008-03-17 2009-09-24 Vereniging Het Nederlands Kanker Instituut Markers providing prognosis of metastasis among cancer patients
TWI526219B (zh) * 2008-06-19 2016-03-21 腫瘤療法 科學股份有限公司 Cdca1抗原決定位胜肽及含此胜肽的疫苗
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same
US20100055705A1 (en) * 2008-08-29 2010-03-04 Wilson Gerald M Compositions and methods for diagnosing and treating cancer
TWI469791B (zh) 2009-02-18 2015-01-21 Oncotherapy Science Inc Foxm1胜肽以及含此胜肽之疫苗
KR101174369B1 (ko) 2009-05-01 2012-08-16 한국생명공학연구원 유방암 진단용 바이오마커 및 유방암 진단제
WO2010138826A1 (en) * 2009-05-29 2010-12-02 University Of Utah Research Foundation Methods and compositions related to cellular assays
US20110217701A1 (en) * 2010-03-03 2011-09-08 Carter Scott L Prognostic Marker for Endometrial Carcinoma
JP2013523186A (ja) * 2010-04-13 2013-06-17 ザ トラスティース オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク 多癌侵襲関連機構に基づくバイオマーカー
EP2426216A1 (en) * 2010-09-01 2012-03-07 Institut Gustave Roussy (IGR) Prognostic and/or predictive biomarkers and biological applications thereof
DK3091085T3 (da) 2010-10-06 2019-05-06 Inst Catalana Recerca Estudis Avancats Fremgangsmåde til at designe en terapi mod brystcancermetastase
US9139881B2 (en) 2010-10-26 2015-09-22 Yamaguchi University Method for assessing breast cancer susceptibility
WO2012066093A1 (en) * 2010-11-19 2012-05-24 Santaris Pharma A/S Compounds for the modulation of pdz-binding kinase (pbk) expression
AU2011351990A1 (en) * 2010-12-29 2013-07-18 Expression Pathology, Inc. Protein biomarkers of recurrent breast cancer
CN102312002A (zh) * 2011-09-20 2012-01-11 李艳 一种快速检测BRCA1基因mRNA表达量的试剂盒
EP2771464B1 (en) * 2011-10-27 2018-03-21 Yeda Research and Development Co. Ltd. Methods of treating cancer
CA3122778A1 (en) 2011-10-28 2013-05-02 Oncotherapy Science, Inc. Topk peptides and vaccines including the same
EP2650682A1 (en) 2012-04-09 2013-10-16 Fundació Privada Institut de Recerca Biomèdica Method for the prognosis and treatment of cancer metastasis
RU2619739C2 (ru) * 2012-05-30 2017-05-17 Федеральное государственное бюджетное учреждение "Российский научный центр рентгенорадиологии" Министерства здравоохранения российской федерации (ФГБУ "РНЦРР" Минздрава России) Способ диагностики и прогноза при гиперпролиферативных заболеваниях молочной железы
US9687538B2 (en) 2012-07-10 2017-06-27 Oncotherapy Science, Inc. CDCA1 epitope peptides for Th1 cells and vaccines containing the same
JP6283861B2 (ja) 2012-09-11 2018-02-28 オンコセラピー・サイエンス株式会社 Ube2tペプチドおよびそれを含むワクチン
ES2878196T3 (es) * 2012-12-26 2021-11-18 Koninklijke Philips Nv Evaluación de la actividad de la vía de señalización celular mediante el uso de una o más combinaciones lineales de expresiones de genes diana
TWI658049B (zh) 2013-03-12 2019-05-01 腫瘤療法 科學股份有限公司 Kntc2胜肽及含此胜肽之疫苗
AU2014333513B2 (en) * 2013-10-09 2020-11-26 Fundacio Institut De Recerca Biomedica (Irb Barcelona) Method for the prognosis and treatment of metastasizing cancer of the bone originating from breast cancer
JP2017512493A (ja) * 2014-03-14 2017-05-25 ブライアン ジェイ ツェルニキCZERNIECKI, Brian, J. 癌のcd4+tヘルパー1型応答の監視方法および免疫回復
CN113321704B (zh) 2014-08-04 2026-05-12 肿瘤疗法科学股份有限公司 Cdca1衍生的肽和含有它们的疫苗
US10311681B2 (en) 2015-08-19 2019-06-04 Mark A. Litman Electronic table game platform with secondary random event displays
US10380834B2 (en) 2015-07-22 2019-08-13 Mark A. Litman Replaceable flexible electronic table top with display function for gaming tables
JP6873482B2 (ja) 2015-10-08 2021-05-19 オンコセラピー・サイエンス株式会社 Foxm1由来ペプチドおよびそれを含むワクチン
US11609427B2 (en) 2015-10-16 2023-03-21 Ostendo Technologies, Inc. Dual-mode augmented/virtual reality (AR/VR) near-eye wearable displays
US11106273B2 (en) * 2015-10-30 2021-08-31 Ostendo Technologies, Inc. System and methods for on-body gestural interfaces and projection displays
KR102541256B1 (ko) 2015-11-30 2023-06-12 (주)아모레퍼시픽 Lipa 억제를 통한 흑색종 예방 또는 치료제, 및 그 스크리닝 방법
KR102475128B1 (ko) 2015-11-30 2022-12-07 (주)아모레퍼시픽 Entpd4 억제를 통한 흑색종 예방 또는 치료제, 및 그 스크리닝 방법
US10345594B2 (en) 2015-12-18 2019-07-09 Ostendo Technologies, Inc. Systems and methods for augmented near-eye wearable displays
US10578882B2 (en) 2015-12-28 2020-03-03 Ostendo Technologies, Inc. Non-telecentric emissive micro-pixel array light modulators and methods of fabrication thereof
US10353203B2 (en) 2016-04-05 2019-07-16 Ostendo Technologies, Inc. Augmented/virtual reality near-eye displays with edge imaging lens comprising a plurality of display devices
US10453431B2 (en) 2016-04-28 2019-10-22 Ostendo Technologies, Inc. Integrated near-far light field display systems
US10522106B2 (en) 2016-05-05 2019-12-31 Ostendo Technologies, Inc. Methods and apparatus for active transparency modulation
MX2018014279A (es) 2016-05-25 2019-07-08 Inbiomotion Sl Tratamiento terapeutico de cancer de mama con base en estado de c-maf.
PT3466978T (pt) * 2016-06-03 2021-05-07 Univ Kyushu Nat Univ Corp Proteína de fusão para melhorar a expressão proteica de arnm alvo
AU2017346972B2 (en) 2016-10-19 2023-01-19 Jetti Resources, Llc Process for leaching metal sulfides with reagents having thiocarbonyl functional groups
EP3548035A4 (en) 2016-11-30 2020-07-22 Case Western Reserve University COMBINATIONS OF 15-PGDH INHIBITORS WITH CORCOSTEROIDS AND / OR TNF INHIBITORS AND THEIR USES
AU2018215678A1 (en) 2017-02-06 2019-08-22 Board Of Regents Of The University Of Texas System Compositions and methods of modulating short-chain dehydrogenase activity
KR102091747B1 (ko) * 2017-11-15 2020-03-20 주식회사 프로탄바이오 유방암 진단용 바이오마커 및 이의 용도
US11654153B2 (en) 2017-11-22 2023-05-23 Inbiomotion S.L. Therapeutic treatment of breast cancer based on c-MAF status
CN108441559B (zh) * 2018-02-27 2021-01-05 海门善准生物科技有限公司 一种免疫相关基因群作为标志物在制备评估高增殖性乳腺癌远处转移风险的产品中的应用
TW202023581A (zh) 2018-08-02 2020-07-01 日商腫瘤療法 科學股份有限公司 來自cdca1的胜肽及含有此的疫苗
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
CN109234384A (zh) * 2018-10-31 2019-01-18 中国医学科学院阜外医院 Hmgcl作为诊断标志物和治疗靶点在致密化不全型心肌病的应用
CA3118585A1 (en) * 2018-11-04 2020-05-07 Pfs Genomics, Inc. Methods and genomic classifiers for prognosis of breast cancer and predicting benefit from adjuvant radiotherapy
IL321451A (en) 2018-11-21 2025-08-01 Univ Case Western Reserve Compositions and methods of modulating short-chain dehydrogenase activity
CN109811059B (zh) * 2019-03-31 2021-10-19 青岛泱深生物医药有限公司 生物标志物uggt1在宫颈疾病中的应用
MX2022010258A (es) 2020-02-21 2023-01-24 Univ Case Western Reserve Composiciones y métodos para tratar la lesión renal.
EP4185862A4 (en) * 2020-09-14 2024-12-25 Duke University COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF DYSTONIA
PE20230857A1 (es) 2020-09-18 2023-05-29 Jetti Resources Llc Extraccion de metales base con un agente humectante y un reactivo de grupo funcional de tiocarbonilo
CN113025720B (zh) * 2021-04-28 2022-12-27 深圳市人民医院 一种用于检测原发性乳腺弥漫性大b细胞淋巴瘤的标志物及其试剂盒和应用
CN113466447B (zh) * 2021-05-28 2024-03-08 天津市肿瘤医院(天津医科大学肿瘤医院) 诊断胰腺癌预后的肿瘤标志物bzw1及检测试剂盒
CN114931665B (zh) * 2021-12-14 2024-09-27 广州医科大学 六型胶原α2亚基在神经修复产品中的应用
CN114334147A (zh) * 2021-12-24 2022-04-12 广东省人民医院 组合的stat信号通路相关基因在结直肠癌预后模型中的应用
CN114561358B (zh) * 2022-03-09 2023-10-03 广州源井生物科技有限公司 一种提高细胞慢病毒感染率的增强感染培养基及方法
CN114561470B (zh) * 2022-03-19 2024-03-01 新乡医学院 三阴性乳腺癌分子标志物及其应用
CN115616214B (zh) * 2022-09-20 2026-03-03 湖南中医药大学 Sox10抗体的应用、试剂盒
US12340627B2 (en) 2022-09-26 2025-06-24 Pison Technology, Inc. System and methods for gesture inference using computer vision
US12366920B2 (en) 2022-09-26 2025-07-22 Pison Technology, Inc. Systems and methods for gesture inference using transformations
US12366923B2 (en) 2022-09-26 2025-07-22 Pison Technology, Inc. Systems and methods for gesture inference using ML model selection
US12502110B2 (en) 2023-10-24 2025-12-23 Pison Technology, Inc. Systems and methods for determining physiological state based on surface biopotentials
CN118243927A (zh) * 2024-04-29 2024-06-25 东莞市石碣医院 eIF3b作为乳腺癌耐药检测靶点的应用
CN119007982A (zh) * 2024-07-26 2024-11-22 大连医科大学附属第二医院 基于肿瘤浸润边缘e-tls预测非小细胞肺癌预后的方法和设备
CN119955854B (zh) * 2025-01-20 2025-09-09 中国人民解放军军事科学院军事医学研究院 一种侏儒症小鼠模型的构建方法及应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
EP1876241A3 (en) * 1996-01-11 2008-07-30 Corixa Corporation Compositions and methods for the treatment and diagnosis of breast cancer
US5968747A (en) * 1997-12-12 1999-10-19 Incyte Pharmaceuticals, Inc. Ubiquitin-like conjugating protein
EP1343886A2 (en) * 2000-07-11 2003-09-17 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US20050064402A1 (en) * 2000-10-03 2005-03-24 Goldsworthy Susan Mcdonald Tumor marker and methods of use
US20030157544A1 (en) * 2000-10-30 2003-08-21 Eos Biotechnology, Inc. Novel methods of diagnosing breast cancer, compositions, and methods of screening for breast cancer modulators
US20030104418A1 (en) * 2001-04-27 2003-06-05 Chao Zhang Diagnostic markers for breast cancer
US7189507B2 (en) * 2001-06-18 2007-03-13 Pdl Biopharma, Inc. Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
AU2003260965A1 (en) 2002-09-30 2004-04-23 Japan As Represented By The President Of The University Of Tokyo Method for diagnosing testicular seminomas
JP5109131B2 (ja) 2005-02-10 2012-12-26 オンコセラピー・サイエンス株式会社 膀胱癌を診断する方法
KR20090064378A (ko) 2006-08-10 2009-06-18 온코세라피 사이언스 가부시키가이샤 유방암 관련 유전자 및 폴리펩티드
TW200908998A (en) * 2007-06-27 2009-03-01 Oncotherapy Science Inc Compositions and methods of treating cancer

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CN1890381B (zh) 2011-06-22
JP2007506426A (ja) 2007-03-22
TW200521243A (en) 2005-07-01
EP1668354A2 (en) 2006-06-14
JP4579246B2 (ja) 2010-11-10
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ES2365732T3 (es) 2011-10-10
US7531300B2 (en) 2009-05-12
CN1890381A (zh) 2007-01-03
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EP1668156B9 (en) 2012-02-22
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US8044193B2 (en) 2011-10-25
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WO2005028676A3 (en) 2005-09-15
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