ATE505720T1 - Vorrichtung zur tiefenselektiven raman- spektroskopie - Google Patents

Vorrichtung zur tiefenselektiven raman- spektroskopie

Info

Publication number
ATE505720T1
ATE505720T1 AT05809242T AT05809242T ATE505720T1 AT E505720 T1 ATE505720 T1 AT E505720T1 AT 05809242 T AT05809242 T AT 05809242T AT 05809242 T AT05809242 T AT 05809242T AT E505720 T1 ATE505720 T1 AT E505720T1
Authority
AT
Austria
Prior art keywords
depth
raman spectroscopy
collected
light
selective
Prior art date
Application number
AT05809242T
Other languages
English (en)
Inventor
Pavel Matousek
Anthony Parker
Original Assignee
Stfc Science & Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34073439&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE505720(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Stfc Science & Technology filed Critical Stfc Science & Technology
Application granted granted Critical
Publication of ATE505720T1 publication Critical patent/ATE505720T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/45—For evaluating or diagnosing the musculoskeletal system or teeth
    • A61B5/4504—Bones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N2021/653—Coherent methods [CARS]
    • G01N2021/656—Raman microprobe
AT05809242T 2004-12-09 2005-11-25 Vorrichtung zur tiefenselektiven raman- spektroskopie ATE505720T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0426993.2A GB0426993D0 (en) 2004-12-09 2004-12-09 Apparatus for depth-selective raman spectroscopy
US66988005P 2005-04-11 2005-04-11
PCT/GB2005/004535 WO2006061566A1 (en) 2004-12-09 2005-11-25 Apparatus for depth-selective raman spectroscopy

Publications (1)

Publication Number Publication Date
ATE505720T1 true ATE505720T1 (de) 2011-04-15

Family

ID=34073439

Family Applications (2)

Application Number Title Priority Date Filing Date
AT05808577T ATE520974T1 (de) 2004-12-09 2005-11-25 Raman-spektralanalyse von unter der oberfläche liegenden geweben und flüssigkeiten
AT05809242T ATE505720T1 (de) 2004-12-09 2005-11-25 Vorrichtung zur tiefenselektiven raman- spektroskopie

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT05808577T ATE520974T1 (de) 2004-12-09 2005-11-25 Raman-spektralanalyse von unter der oberfläche liegenden geweben und flüssigkeiten

Country Status (10)

Country Link
US (3) US7652763B2 (de)
EP (2) EP1831673B1 (de)
JP (2) JP2008523375A (de)
CN (2) CN101115987B (de)
AT (2) ATE520974T1 (de)
AU (2) AU2005313144A1 (de)
CA (2) CA2591303A1 (de)
DE (1) DE602005027485D1 (de)
GB (1) GB0426993D0 (de)
WO (2) WO2006061566A1 (de)

Families Citing this family (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0512336A (pt) 2004-06-22 2008-03-04 Crescent Diagnostics Ireland L métodos de diagnósticos para osteoporose
GB0426993D0 (en) 2004-12-09 2005-01-12 Council Cent Lab Res Councils Apparatus for depth-selective raman spectroscopy
JP2007007267A (ja) * 2005-07-01 2007-01-18 Kanazawa Univ 骨密度計測装置
US7729749B2 (en) * 2005-09-01 2010-06-01 The Regents Of The University Of Michigan Method and apparatus for evaluating connective tissue conditions
CA2550390C (en) 2005-09-16 2014-10-21 The Regents Of The University Of Michigan Method and system for measuring sub-surface composition of a sample
GB0606891D0 (en) 2006-04-05 2006-05-17 Council Cent Lab Res Councils Raman Analysis Of Pharmaceutical Tablets
FR2899972B1 (fr) * 2006-04-14 2008-12-19 Centre Nat Machinisme Agricole Dispositif et procede d'analyse d'echantillon biologique par spectroscopie resolue spatialement
US7742166B2 (en) * 2006-04-27 2010-06-22 C8 Medisensors Inc. Enhancing selectivity and/or sensitivity of spectroscopic measurements in media
EP2023812B1 (de) 2006-05-19 2016-01-27 The Queen's Medical Center Bewegungsverfolgungssystem für adaptive echtzeitabbildung und -spektroskopie
GB2447497A (en) * 2007-03-15 2008-09-17 Council Cent Lab Res Councils Illumination of diffusely scattering media
JP4674910B2 (ja) * 2007-03-29 2011-04-20 セキテクノトロン株式会社 ラマン分光法による結晶多形の自動判定方法及びその装置
GB2448546B (en) * 2007-04-20 2009-12-23 Crescent Diagnostics Apparatus for acquiring data relative to the structure of fingernail material
EP2081017A1 (de) * 2008-01-16 2009-07-22 FOSS Analytical AB Offset-Sonde
WO2009137740A1 (en) * 2008-05-09 2009-11-12 Hugh Beckman Medical device for diagnosing and treating anomalous tissue and method for doing the same
CN104939806B (zh) 2008-05-20 2021-12-10 大学健康网络 用于基于荧光的成像和监测的装置和方法
US9020581B2 (en) * 2008-12-05 2015-04-28 Vanderbilt University Spatially offset Raman spectroscopy of layered soft tissues and applications of same
SE533454C2 (sv) * 2008-12-18 2010-10-05 Portendo Ab Detektion av små mängder av ämnen
KR20110034265A (ko) * 2009-09-28 2011-04-05 엘지전자 주식회사 생체 검사 기능을 갖는 캡슐 내시경 및 그 제어방법
JP5709368B2 (ja) * 2009-11-04 2015-04-30 キヤノン株式会社 生体情報取得装置
CA2781393C (en) 2009-11-19 2017-08-08 Modulated Imaging, Inc. Method and apparatus for analysis of turbid media via single-element detection using structured illumination
GB201000179D0 (en) 2010-01-07 2010-02-24 Rsp Systems As Apparatus for non-invasive in vivo measurement by raman spectroscopy
US10561318B2 (en) 2010-01-25 2020-02-18 University Health Network Device, system and method for quantifying fluorescence and optical properties
JP5060580B2 (ja) * 2010-04-09 2012-10-31 トヨタ自動車株式会社 スペクトル測定装置
CN101949840B (zh) * 2010-08-17 2011-11-16 中国农业大学 生肉肌红蛋白快速无损检测方法及系统
GB201219189D0 (en) * 2012-10-25 2012-12-12 Renishaw Plc Spectroscopic apparatus and methods
AT511512B1 (de) 2011-05-20 2013-02-15 Univ Wien Tech Vorrichtung zur detektion von reflektiertem, in einem objekt gestreuten licht
US9606209B2 (en) 2011-08-26 2017-03-28 Kineticor, Inc. Methods, systems, and devices for intra-scan motion correction
US20130090537A1 (en) * 2011-10-07 2013-04-11 2M Engineering Limited Blood glucose sensor
US20130237849A1 (en) * 2012-03-12 2013-09-12 Ivwatch, Llc Geometry of a Transcutaneous Sensor
US9155473B2 (en) * 2012-03-21 2015-10-13 Korea Electrotechnology Research Institute Reflection detection type measurement apparatus for skin autofluorescence
US20150018646A1 (en) * 2013-07-12 2015-01-15 Sandeep Gulati Dynamic sample mapping noninvasive analyzer apparatus and method of use thereof
WO2014060983A1 (en) * 2012-10-18 2014-04-24 Koninklijke Philips N.V. Arrangement for an analysis system, analysis system having the arrangement and method for use of the arrangement
EP2917734A4 (de) * 2012-11-06 2016-09-07 Chemimage Corp System und verfahren für serumbasierte krebserkennung
EP3401678B1 (de) 2012-11-07 2020-04-08 Modulated Imaging Inc. Effiziente modulierte bildgebung
US9717461B2 (en) 2013-01-24 2017-08-01 Kineticor, Inc. Systems, devices, and methods for tracking and compensating for patient motion during a medical imaging scan
US9305365B2 (en) 2013-01-24 2016-04-05 Kineticor, Inc. Systems, devices, and methods for tracking moving targets
US10327708B2 (en) 2013-01-24 2019-06-25 Kineticor, Inc. Systems, devices, and methods for tracking and compensating for patient motion during a medical imaging scan
WO2014120734A1 (en) 2013-02-01 2014-08-07 Kineticor, Inc. Motion tracking system for real time adaptive motion compensation in biomedical imaging
US9629629B2 (en) 2013-03-14 2017-04-25 Ethicon Endo-Surgey, LLC Control systems for surgical instruments
US9888855B2 (en) * 2013-03-18 2018-02-13 Korea Electrotechnology Research Institute Reflection detection type measurement apparatus and method for skin autofluorescence
US20150201840A1 (en) * 2013-03-18 2015-07-23 Korea Electrotechnology Research Institute Reflection detection type measurement apparatus for skin autofluorescence
AU2014261003B2 (en) 2013-05-02 2019-03-28 Atonarp Inc. Monitor and system for monitoring living organisms
JP2016523608A (ja) 2013-06-06 2016-08-12 プロフサ，インコーポレイテッド 埋込センサからの光信号を検出する装置及び方法
US9645086B2 (en) * 2013-08-30 2017-05-09 Kabushiki Kaisha Toshiba Componential analysis method, componential analysis apparatus and non-transitory computer-readable recording medium
US10004462B2 (en) 2014-03-24 2018-06-26 Kineticor, Inc. Systems, methods, and devices for removing prospective motion correction from medical imaging scans
WO2016014718A1 (en) 2014-07-23 2016-01-28 Kineticor, Inc. Systems, devices, and methods for tracking and compensating for patient motion during a medical imaging scan
ES2894912T3 (es) 2014-07-24 2022-02-16 Univ Health Network Recopilación y análisis de datos con fines de diagnóstico
US10352862B2 (en) * 2014-08-18 2019-07-16 Nanophoton Corporation Raman spectroscopic microscope and Raman scattered light observation method
TWI673497B (zh) * 2014-08-29 2019-10-01 亞多納富有限公司 監視生物體的監視器及其控制方法及健康管理系統
US10436716B2 (en) * 2014-09-24 2019-10-08 Smiths Detection, Inc. Ubiquitous transmissive raman spectroscopy for stand-off detection
US10072984B2 (en) * 2014-10-02 2018-09-11 Mks Technology, Inc. Spectrometer
KR102323212B1 (ko) * 2014-11-07 2021-11-09 삼성전자주식회사 위치 변동을 보상할 수 있는 분광 시스템 및 이를 이용한 분광 방법
KR102395773B1 (ko) * 2014-11-07 2022-05-09 삼성전자주식회사 생체 시료의 분석 시스템 및 이를 이용한 분석 방법
CN104545812A (zh) * 2014-12-30 2015-04-29 中国科学院长春光学精密机械与物理研究所 探测深度可控的人体生化指标无创检测装置
FR3032527B1 (fr) * 2015-02-06 2020-03-13 Commissariat A L'energie Atomique Et Aux Energies Alternatives Dispositif de mesure d'un signal optique retrodiffuse par un echantillon
US10288814B2 (en) 2015-03-25 2019-05-14 Board Of Regents Of The University Of Texas System Variable spatial offset fiber optic probe for optical spectography and imaging
GB201511318D0 (en) * 2015-06-29 2015-08-12 Secr Defence Improved spatially-offset raman spectroscopy
GB201511574D0 (en) 2015-07-01 2015-08-12 Stfc Science & Technology Clinical thermometer
GB201511696D0 (en) 2015-07-03 2015-08-19 Cobalt Light Systems Ltd Scanner for spatially offset raman spectrscopy
US9943247B2 (en) 2015-07-28 2018-04-17 The University Of Hawai'i Systems, devices, and methods for detecting false movements for motion correction during a medical imaging scan
TWI696822B (zh) * 2015-10-05 2020-06-21 財團法人工業技術研究院 載子濃度的量測方法及其設備
WO2017070637A1 (en) 2015-10-23 2017-04-27 The Trustees Of Columbia University In The City Of New York Laser induced collagen crosslinking in tissue
JP6786338B2 (ja) * 2015-10-29 2020-11-18 アークレイ株式会社 血液測定装置
CN105352934B (zh) * 2015-11-05 2019-03-08 北京农业智能装备技术研究中心 便携式拉曼探头及检测装置
WO2017091479A1 (en) 2015-11-23 2017-06-01 Kineticor, Inc. Systems, devices, and methods for tracking and compensating for patient motion during a medical imaging scan
CN105520719A (zh) * 2016-01-25 2016-04-27 上海电力学院 一种基于红外光谱的早期癌细胞检测系统
KR101801115B1 (ko) * 2016-04-04 2017-11-27 스페클립스 주식회사 레이저 조사 장치를 이용한 질병 진단 및 피부 나이 측정 장치와 탈부착 핸드피스
KR101778047B1 (ko) * 2016-04-04 2017-09-13 스페클립스 주식회사 질병 진단과 피부 나이 측정이 가능한 시스템과 이에 사용되는 핸드피스
WO2017214604A1 (en) 2016-06-10 2017-12-14 The Trustees Of Columbia University In The City Of New York Devices, methods, and systems for detection of collagen tissue features
CN106198490B (zh) * 2016-08-17 2023-08-18 中国原子能科学研究院 一种空间偏移拉曼光谱探测系统
CN107870399A (zh) * 2016-09-27 2018-04-03 福州高意光学有限公司 一种特殊光接受结构
GB201618260D0 (en) 2016-10-28 2016-12-14 Science And Tech Facilities Council The Detection of pH
KR20180051196A (ko) * 2016-11-08 2018-05-16 삼성전자주식회사 분광기, 생체정보 측정 장치 및 방법
US10119917B2 (en) 2016-11-11 2018-11-06 B & W Tek LLC Apparatus and method for bidirectional Raman spectroscopy
US10126244B2 (en) 2016-11-11 2018-11-13 B&W Tek Llc Apparatuses and methods for performing spectroscopic analysis of a subject
US10119916B2 (en) 2016-11-11 2018-11-06 B&W Tek Llc Light delivery and collection device for measuring Raman scattering of a sample
US10113969B2 (en) 2016-11-11 2018-10-30 B&W Tek Llc Methods and devices for measuring Raman scattering of a sample
CN106404746B (zh) * 2016-11-24 2019-09-10 中国科学院长春光学精密机械与物理研究所 一种CaF2光学基底表面和亚表面损伤探测方法
WO2018134980A1 (ja) * 2017-01-20 2018-07-26 オリンパス株式会社 軟骨組織の分析装置
BR112019015561B1 (pt) * 2017-01-30 2023-12-12 Medibeacon Inc Método para monitorar uma fluorescência variável no tempo emitida de um agente fluorescente exógeno de dentro de um meio refletor difuso
US11035797B2 (en) 2017-04-28 2021-06-15 Biospex, Inc. Hybrid time-resolved and time-shifted spectroscopy for measuring biological analytes
US10548481B2 (en) * 2017-04-28 2020-02-04 Biospex, Inc. Non-invasive measurement of biological analytes
US10876892B2 (en) * 2017-04-28 2020-12-29 Biospex, Inc. Measuring biological analytes using time-resolved spectroscopy
CN109425572B (zh) 2017-08-30 2023-07-25 三星电子株式会社 用于光谱仪的收集光学系统和拉曼光谱系统
EP3454023A1 (de) * 2017-08-30 2019-03-13 Samsung Electronics Co., Ltd. Sammeloptiksystem für spektrometer und raman-spektralsystem
KR102526757B1 (ko) * 2017-08-30 2023-04-27 삼성전자주식회사 분광기용 집광 광학계 및 이를 포함하는 라만 분광 시스템
CN109752361A (zh) * 2017-11-03 2019-05-14 桂林电子科技大学 推挽式光纤拉曼谱仪
US11666481B1 (en) 2017-12-01 2023-06-06 The Trustees Of Columbia University In The City Of New York Diagnosis and treatment of collagen-containing tissues
CN108802005B (zh) * 2018-06-05 2021-08-24 河海大学常州校区 基于粒子-波导耦合结构的拉曼散射增强基底及制备方法
GB2572662B (en) 2018-10-05 2020-06-03 Res & Innovation Uk Raman spectrometer
US10760969B1 (en) 2019-02-28 2020-09-01 Biospex, Inc. Fluorescence and systemic noise reduction in time-gated spectroscopy
WO2020191347A1 (en) * 2019-03-21 2020-09-24 Dawatek, Llc Offset raman imaging system and methods of use
CN112292065A (zh) 2019-03-22 2021-01-29 斯佩克里普斯公司 使用激光诱导击穿光谱法的诊断方法及执行该方法的诊断装置
WO2020206420A1 (en) * 2019-04-05 2020-10-08 Cytoveris Inc. Angular depth resolved raman spectroscopy apparatus and method
US10881301B2 (en) 2019-05-07 2021-01-05 Biospex, Inc. Spatial optimization for measuring biological analytes
JP7325736B2 (ja) * 2019-07-08 2023-08-15 学校法人早稲田大学 光学測定装置
US11326944B2 (en) 2019-07-12 2022-05-10 Biospex, Inc. Wearable spectrometer with filtered sensor
US11454540B2 (en) 2019-07-12 2022-09-27 Biospex, Inc. Wearable spectroscopy using filtered sensor
GB201910801D0 (en) 2019-07-29 2019-09-11 Agilent Tech Lda Uk Limited Raman analysis of pharmaceutical dosage forms
CN110501321B (zh) * 2019-07-31 2022-03-01 西北大学 集拉曼光谱快速成像和深层光谱快速检测于一体的便携式光路系统
US20210059582A1 (en) * 2019-08-30 2021-03-04 Jeon Woong Kang Non-Invasive Glucose Monitoring by Raman Spectroscopy
CN110680515A (zh) * 2019-10-28 2020-01-14 郑超 一种术中实时检测乳腺癌切缘的光纤探头及装置
CN110987898A (zh) * 2019-12-06 2020-04-10 中国科学院合肥物质科学研究院 一种空间外差偏移拉曼光谱检测装置及其检测方法
KR20210075648A (ko) 2019-12-13 2021-06-23 삼성전자주식회사 소형 라만 센서 및 생체성분 추정 장치
US20210228083A1 (en) * 2020-01-23 2021-07-29 Precision Healing, Inc. Skin diagnostics using optical signatures
GB202004010D0 (en) 2020-03-19 2020-05-06 Res & Innovation Uk Detection of water content in tissue
EP4127678A1 (de) * 2020-03-26 2023-02-08 Innovative Photonic Solutions, Inc. Verfahren zur auswahl von ramananregungswellenlängen in einer ramansonde mit mehreren quellen
EP3901618A1 (de) * 2020-03-30 2021-10-27 TimeGate Instruments Oy Verfahren und vorrichtung zur messung des spektrums von raman-gestreutem licht unter verwendung von zeitgesteuerter detektion
GB2596804A (en) 2020-07-06 2022-01-12 Agilent Tech Lda Uk Limited Raman analysis of pharmaceutical dosage forms
WO2022039255A1 (ja) * 2020-08-20 2022-02-24 アトナープ株式会社 インプラント、生体監視システムおよび生体管理システム
GB2600152A (en) 2020-10-23 2022-04-27 Rsp Systems As Apparatus and method for non-invasive in vivo measurements of analyte presence or concentration
CN113252636B (zh) * 2021-05-06 2022-10-04 河北大学 深度识别拉曼光谱分析系统及分析方法
CN113970539B (zh) * 2021-10-08 2022-12-20 上海交通大学 一种快速检测包装容器内物质的拉曼光谱方法
GB2615370A (en) 2022-02-08 2023-08-09 Res & Innovation Uk Detection using SERS probes
CN115436340B (zh) * 2022-11-08 2023-03-07 北京工业大学 一种无损、快速检测医用导管表面覆有功能涂层的方法

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6058820B2 (ja) 1979-07-31 1985-12-21 工業技術院長 透明物質の表面分析方法
US4570638A (en) 1983-10-14 1986-02-18 Somanetics Corporation Method and apparatus for spectral transmissibility examination and analysis
US5139025A (en) 1983-10-14 1992-08-18 Somanetics Corporation Method and apparatus for in vivo optical spectroscopic examination
JPH0368070A (ja) * 1989-08-08 1991-03-25 Sony Corp 行列データ乗算装置
US5261410A (en) 1991-02-07 1993-11-16 Alfano Robert R Method for determining if a tissue is a malignant tumor tissue, a benign tumor tissue, or a normal or benign tissue using Raman spectroscopy
US6690966B1 (en) * 1991-02-26 2004-02-10 Massachusetts Institute Of Technology Methods of molecular spectroscopy to provide for the diagnosis of tissue
US5194913A (en) 1991-03-20 1993-03-16 The United States Of America As Represented By The United States Department Of Energy Fiber-optic apparatus and method for measurement of luminescence and raman scattering
US5371368A (en) * 1992-07-23 1994-12-06 Alfano; Robert R. Ultrafast optical imaging of objects in a scattering medium
US5746210A (en) * 1993-02-26 1998-05-05 David A. Benaron Device and method for detection, localization, and characterization of inhomogeneities in turbid media
US5421329A (en) * 1994-04-01 1995-06-06 Nellcor, Inc. Pulse oximeter sensor optimized for low saturation
US5565982A (en) * 1994-05-31 1996-10-15 Recon Exploration Apparatus and method for time resolved spectroscopy
US5625458A (en) 1994-11-10 1997-04-29 Research Foundation Of City College Of New York Method and system for imaging objects in turbid media using diffusive fermat photons
US5660181A (en) 1994-12-12 1997-08-26 Physical Optics Corporation Hybrid neural network and multiple fiber probe for in-depth 3-D mapping
US5919140A (en) 1995-02-21 1999-07-06 Massachusetts Institute Of Technology Optical imaging using time gated scattered light
US5615673A (en) 1995-03-27 1997-04-01 Massachusetts Institute Of Technology Apparatus and methods of raman spectroscopy for analysis of blood gases and analytes
US5999836A (en) 1995-06-06 1999-12-07 Nelson; Robert S. Enhanced high resolution breast imaging device and method utilizing non-ionizing radiation of narrow spectral bandwidth
US5636633A (en) 1995-08-09 1997-06-10 Rio Grande Medical Technologies, Inc. Diffuse reflectance monitoring apparatus
JP3588880B2 (ja) * 1995-11-17 2004-11-17 株式会社日立製作所 生体光計測装置
CA2210703C (en) 1995-11-17 2001-10-09 Hitachi, Ltd. Optical measurement instrument for living body
US5842995A (en) 1996-06-28 1998-12-01 Board Of Regents, The Univerisity Of Texas System Spectroscopic probe for in vivo measurement of raman signals
US5873831A (en) 1997-03-13 1999-02-23 The University Of Utah Technology Transfer Office Method and system for measurement of macular carotenoid levels
US6483581B1 (en) 1997-07-02 2002-11-19 Spectra Code, Inc. Raman system for rapid sample indentification
AU2473699A (en) * 1998-01-27 1999-08-09 Lightouch Medical, Inc. Method and device for tissue modulation
US6078833A (en) * 1998-03-25 2000-06-20 I.S.S. (Usa) Inc. Self referencing photosensor
EP1073366B1 (de) 1998-04-24 2004-06-23 Lightouch Medical, Inc. Gerät und verfahren zur thermischen modulation von gewebe
ATE225142T1 (de) 1998-07-07 2002-10-15 Lightouch Medical Inc Verfahren zur gewebemodulation für die quantitative nichtinvasive in vivo spektroskopische analyse von gewebe
JP2000065696A (ja) * 1998-08-19 2000-03-03 Mitsubishi Chemicals Corp フィルタ装置及びフィルタ装置を有する硫黄分析システム
GB9819732D0 (en) 1998-09-11 1998-11-04 Renishaw Plc Tool conditioning monitoring
WO2000020843A1 (en) 1998-10-07 2000-04-13 Ecole Polytechnique Federale De Lausanne (Epfl) Method and apparatus for measuring locally and superficially the scattering and absorption properties of turbid media
US6352502B1 (en) 1998-12-03 2002-03-05 Lightouch Medical, Inc. Methods for obtaining enhanced spectroscopic information from living tissue, noninvasive assessment of skin condition and detection of skin abnormalities
JP4107456B2 (ja) * 1999-01-14 2008-06-25 微小循環研究所 有限会社 毛細血管血流観測装置
JP3743191B2 (ja) * 1999-02-08 2006-02-08 Ｊｆｅスチール株式会社 渦流探傷法
JP3796086B2 (ja) 1999-12-27 2006-07-12 株式会社日立製作所 生体光計測装置
AU2001231042A1 (en) 2000-01-21 2001-07-31 Stephen T Flock Optical measurements of bone composition
DE10027100C2 (de) * 2000-05-31 2002-08-08 Klaus Mueller-Dethlefs Verfahren und Vorrichtung zum Nachweisen von Substanzen in Körperflüssigkeiten
ATE417543T1 (de) 2000-07-13 2009-01-15 Univ Virginia Commonwealth Verwendung von ultraviolett, nahultraviolett und nahinfrarot-resonanzrmanspektroskopie und fluoresenzspektoskopie zur gewebeuntersuchung auf schockzustand, kritische krankheiten oder andere krankheitszustände
JP2002085385A (ja) 2000-09-21 2002-03-26 Sadako Honda 血糖値の測定方法および測定装置
IL138683A0 (en) * 2000-09-25 2001-10-31 Vital Medical Ltd Apparatus and method for monitoring tissue vitality parameters
JP4486743B2 (ja) * 2000-10-31 2010-06-23 株式会社町田製作所 血管内壁の付着物質の分析システム
US6609015B2 (en) * 2001-01-18 2003-08-19 Koninklijke Philips Electronics N.V. Analysis of a composition
EP1365033A4 (de) * 2001-03-01 2004-04-07 Fujisawa Pharmaceutical Co Verfahren zur molekularen diagnose chronischer myelogener leukämie
US6954667B2 (en) 2001-06-28 2005-10-11 Chemimage Corporation Method for Raman chemical imaging and characterization of calcification in tissue
JP2003010189A (ja) 2001-07-04 2003-01-14 Communication Research Laboratory 生体機能情報撮像装置
KR100976784B1 (ko) 2001-09-12 2010-08-19 게르잔 에스테블리쉬먼트 다이아몬드 검사
JP2003102672A (ja) * 2001-10-01 2003-04-08 Japan Science & Technology Corp 病変等の対象部位を自動的に検知かつ治療または採取する方法およびその装置
US6870165B2 (en) * 2001-10-19 2005-03-22 Biocal Technology, Inc. Multi-color multiplexed analysis in a bio-separation system
US20050037615A1 (en) 2001-11-06 2005-02-17 Dario Cabib In-line spectroscopy for process monitoring
US6825928B2 (en) 2001-12-19 2004-11-30 Wisconsin Alumni Research Foundation Depth-resolved fluorescence instrument
US6873868B2 (en) 2001-12-31 2005-03-29 Infraredx, Inc. Multi-fiber catheter probe arrangement for tissue analysis or treatment
EP1475037B1 (de) 2002-02-14 2012-09-12 Toshinori Kato Gerät zur beurteilung einer biologischen funktion
AU2002236343A1 (en) 2002-02-28 2003-09-09 Erasmus Universiteit Rotterdam Depth selective ph measurement and uv exposure measurement
US7647092B2 (en) 2002-04-05 2010-01-12 Massachusetts Institute Of Technology Systems and methods for spectroscopy of biological tissue
JP4588324B2 (ja) * 2002-04-05 2010-12-01 マサチユセツツ・インスチチユート・オブ・テクノロジイ 組織測定用プローブ
EP2522294A2 (de) * 2002-10-23 2012-11-14 Palomar Medical Technologies, Inc. Photobehandlungsvorrichtung zur Verwendung mit Kühlmitteln und topischen Substanzen
WO2004051242A1 (en) 2002-12-02 2004-06-17 Erasmus Universiteit Rotterdam Use of high wavenumber raman spectroscopy for measuring tissue
JP4136704B2 (ja) 2003-02-19 2008-08-20 株式会社島津製作所 光計測装置用のプローブとそれを用いたマルチチャンネル光計測装置
EP1601288B1 (de) * 2003-03-05 2012-05-09 InfraReDx, Inc. Kathetersondenanordnung für gewebeanalyse mittels strahlungsenergieabgabe und strahlungsenergiesammlung
JP2004294150A (ja) 2003-03-26 2004-10-21 Univ Waseda 分光分析装置及び分光分析法
WO2004097365A2 (en) 2003-04-30 2004-11-11 Mcgill University Method and system for measuring lactate levels in vivo
EP1638455A1 (de) 2003-07-01 2006-03-29 The Regents of The University of Michigan Methode und gerät zur diagnose von knochenzuständen
GB0426993D0 (en) * 2004-12-09 2005-01-12 Council Cent Lab Res Councils Apparatus for depth-selective raman spectroscopy
CA2550390C (en) 2005-09-16 2014-10-21 The Regents Of The University Of Michigan Method and system for measuring sub-surface composition of a sample

Also Published As

Publication number Publication date
CA2591306A1 (en) 2006-06-15
CN101115987B (zh) 2011-08-31
GB0426993D0 (en) 2005-01-12
US7652763B2 (en) 2010-01-26
JP2008522697A (ja) 2008-07-03
AU2005313145B2 (en) 2011-10-06
US20080129992A1 (en) 2008-06-05
DE602005027485D1 (de) 2011-05-26
CN101115987A (zh) 2008-01-30
CA2591303A1 (en) 2006-06-15
US20100091276A1 (en) 2010-04-15
WO2006061565A1 (en) 2006-06-15
JP2008523375A (ja) 2008-07-03
US8243269B2 (en) 2012-08-14
EP1828753A1 (de) 2007-09-05
US8159664B2 (en) 2012-04-17
ATE520974T1 (de) 2011-09-15
EP1831673A1 (de) 2007-09-12
AU2005313145A1 (en) 2006-06-15
EP1831673B1 (de) 2011-08-17
US20080076985A1 (en) 2008-03-27
CN101115986B (zh) 2011-08-31
EP1828753B1 (de) 2011-04-13
AU2005313144A1 (en) 2006-06-15
CN101115986A (zh) 2008-01-30
WO2006061566A1 (en) 2006-06-15

Similar Documents

Publication Publication Date Title
ATE505720T1 (de) Vorrichtung zur tiefenselektiven raman- spektroskopie
ATE476908T1 (de) System und diagnoseverfahren zur optischen detektion von verdächtigen stellen einer gewebeprobe
ATE404110T1 (de) Vorrichtung zur nichtinvasiven bestimmung des sauerstoffumsatzes in geweben
DE602004013101D1 (de) Automatische Vorrichtung zur Aufnahme und Sammeln von Urin
ATE532462T1 (de) Probenentnahmegerät zur entnahme mehrerer proben
ATE418259T1 (de) Verfahren zur bodenflächenanalyse und rasenpflege-roboter zur durchführung des verfahrens
ATE481032T1 (de) Vorrichtung, system und verfahren zur in-vivo- probenentnahme
WO2006052634A3 (en) Non-invasive measurement system and method for measuring the concentration of an optically-active substance
TW200643400A (en) Optical-based sensing devices
FR2872922B1 (fr) Procede et appareil d'acquisition vribratoire sismique
DE60304755D1 (de) Vorrichtung zur Bestimmung von Thrombosen tiefliegender Venen
WO2003096272A1 (en) Method of detecting biological pattern, biological pattern detector, method of biological certificate and biological certificate apparatus
WO2009076590A3 (en) Extended spectral sensitivity endoscope system and method of using the same
DE60325422D1 (de) Vorrichtung zur messung biologischer informationen
DE502005006309D1 (de) Vorrichtung und Verfahren zur Röntgenanalyse mit zweidimensionalem Array-Detektor
ATE509664T1 (de) Vorrichtung zur durchführung ästhetischer behandlungen
EP1627599A3 (de) Berrechnungsvorrichtung für biologische Information sowie entsprechendes Verfahren, Programm und Speichermedium
WO2009059072A3 (en) Analysis of endogenous fluorescence images to extract morphological/organization information about living samples
TW200716965A (en) Methods of using raman spectral information in determining analyte concentrations
WO2002003857A3 (en) Method of tissue modulation for noninvasive measurement of an analyte
WO2008024288A3 (en) Non-invasive methods of using spectral information in determining analyte concentrations
DE60300146D1 (de) Vorrichtung zur Bestimmung der muskularen Erschöpfung
DE60314388D1 (de) Vorrichtung zur Messung des Blutzuckerspiegels
DE602004023543D1 (de) Implantierbare medizinische vorrichtung
DE602004020882D1 (de) Vorrichtung zur differenziellen oberflächenplasmonenresonanzmessung und messverfahren

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties