ATE503024T1 - Nachweis chromosomaler störungen - Google Patents
Nachweis chromosomaler störungenInfo
- Publication number
- ATE503024T1 ATE503024T1 AT05740284T AT05740284T ATE503024T1 AT E503024 T1 ATE503024 T1 AT E503024T1 AT 05740284 T AT05740284 T AT 05740284T AT 05740284 T AT05740284 T AT 05740284T AT E503024 T1 ATE503024 T1 AT E503024T1
- Authority
- AT
- Austria
- Prior art keywords
- dna
- targeted
- chromosomal disorders
- spots
- imaging
- Prior art date
Links
- 208000011359 Chromosome disease Diseases 0.000 title abstract 4
- 208000024971 chromosomal disease Diseases 0.000 title abstract 4
- 238000001514 detection method Methods 0.000 title 1
- 108020004414 DNA Proteins 0.000 abstract 6
- 238000003384 imaging method Methods 0.000 abstract 3
- 238000003752 polymerase chain reaction Methods 0.000 abstract 3
- 238000002493 microarray Methods 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000053602 DNA Human genes 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- 108020005187 Oligonucleotide Probes Proteins 0.000 abstract 1
- 108020004682 Single-Stranded DNA Proteins 0.000 abstract 1
- 208000036878 aneuploidy Diseases 0.000 abstract 1
- 231100001075 aneuploidy Toxicity 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 210000000349 chromosome Anatomy 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 239000002751 oligonucleotide probe Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Organic Insulating Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/840,208 US7468249B2 (en) | 2004-05-05 | 2004-05-05 | Detection of chromosomal disorders |
| PCT/US2005/013070 WO2005111237A1 (en) | 2004-05-05 | 2005-04-18 | Detection of chromosomal disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE503024T1 true ATE503024T1 (de) | 2011-04-15 |
Family
ID=34967157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05740284T ATE503024T1 (de) | 2004-05-05 | 2005-04-18 | Nachweis chromosomaler störungen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7468249B2 (https=) |
| EP (1) | EP1759011B1 (https=) |
| JP (1) | JP5032304B2 (https=) |
| KR (1) | KR101176091B1 (https=) |
| CN (1) | CN1981052A (https=) |
| AT (1) | ATE503024T1 (https=) |
| DE (1) | DE602005027067D1 (https=) |
| WO (1) | WO2005111237A1 (https=) |
Families Citing this family (84)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6913697B2 (en) | 2001-02-14 | 2005-07-05 | Science & Technology Corporation @ Unm | Nanostructured separation and analysis devices for biological membranes |
| CA2500392C (en) | 2002-09-27 | 2012-11-27 | The General Hospital Corporation | Microfluidic device for cell separation and uses thereof |
| US8024128B2 (en) * | 2004-09-07 | 2011-09-20 | Gene Security Network, Inc. | System and method for improving clinical decisions by aggregating, validating and analysing genetic and phenotypic data |
| US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
| EP2477029A1 (en) | 2005-06-02 | 2012-07-18 | Fluidigm Corporation | Analysis using microfluidic partitioning devices |
| US11111544B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US11111543B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US10081839B2 (en) | 2005-07-29 | 2018-09-25 | Natera, Inc | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US8515679B2 (en) * | 2005-12-06 | 2013-08-20 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US8532930B2 (en) | 2005-11-26 | 2013-09-10 | Natera, Inc. | Method for determining the number of copies of a chromosome in the genome of a target individual using genetic data from genetically related individuals |
| US20070027636A1 (en) * | 2005-07-29 | 2007-02-01 | Matthew Rabinowitz | System and method for using genetic, phentoypic and clinical data to make predictions for clinical or lifestyle decisions |
| US10083273B2 (en) | 2005-07-29 | 2018-09-25 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US20070178501A1 (en) * | 2005-12-06 | 2007-08-02 | Matthew Rabinowitz | System and method for integrating and validating genotypic, phenotypic and medical information into a database according to a standardized ontology |
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
| WO2007080583A2 (en) * | 2006-01-10 | 2007-07-19 | Applied Spectral Imaging Ltd. | Methods and systems for analyzing biological samples |
| EP2589668A1 (en) * | 2006-06-14 | 2013-05-08 | Verinata Health, Inc | Rare cell analysis using sample splitting and DNA tags |
| WO2007147074A2 (en) | 2006-06-14 | 2007-12-21 | Living Microsystems, Inc. | Use of highly parallel snp genotyping for fetal diagnosis |
| US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
| US20080090239A1 (en) * | 2006-06-14 | 2008-04-17 | Daniel Shoemaker | Rare cell analysis using sample splitting and dna tags |
| US20080050739A1 (en) | 2006-06-14 | 2008-02-28 | Roland Stoughton | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
| US20080090237A1 (en) * | 2006-10-13 | 2008-04-17 | Zohar Yakhini | Methods and compositions for comparing chromosomal copy number between genomic samples |
| KR100920134B1 (ko) | 2007-06-29 | 2009-10-08 | 차의과학대학교 산학협력단 | Ｙ 염색체 미세결실 검출용 마이크로어레이 및 이를이용한 검출방법 |
| CA2717320A1 (en) | 2008-03-11 | 2009-09-17 | Sequenom, Inc. | Nucleic acid-based tests for prenatal gender determination |
| CN102171565B (zh) | 2008-08-04 | 2015-04-29 | 纳特拉公司 | 等位基因调用和倍性调用的方法 |
| US8476013B2 (en) | 2008-09-16 | 2013-07-02 | Sequenom, Inc. | Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
| US8962247B2 (en) | 2008-09-16 | 2015-02-24 | Sequenom, Inc. | Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses |
| HUE031848T2 (en) | 2008-09-20 | 2017-08-28 | Univ Leland Stanford Junior | Non-invasive diagnosis of fetal aneuploidy by sequencing |
| EP2373817A4 (en) * | 2008-12-10 | 2013-01-02 | Illumina Inc | METHOD AND COMPOSITIONS FOR HYBRIDIZING NUCLEIC ACIDS |
| US20120215459A1 (en) * | 2009-09-04 | 2012-08-23 | Marianne Stef | High throughput detection of genomic copy number variations |
| US20120185176A1 (en) | 2009-09-30 | 2012-07-19 | Natera, Inc. | Methods for Non-Invasive Prenatal Ploidy Calling |
| EP3088532B1 (en) | 2009-12-22 | 2019-10-30 | Sequenom, Inc. | Processes and kits for identifying aneuploidy |
| US8774488B2 (en) | 2010-03-11 | 2014-07-08 | Cellscape Corporation | Method and device for identification of nucleated red blood cells from a maternal blood sample |
| US12545960B2 (en) | 2010-05-18 | 2026-02-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| EP2572003A4 (en) | 2010-05-18 | 2016-01-13 | Natera Inc | METHOD FOR NONINVASIVE PRANATAL PLOIDIE ASSIGNMENT |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11332793B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11339429B2 (en) | 2010-05-18 | 2022-05-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11332785B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| US11326208B2 (en) | 2010-05-18 | 2022-05-10 | Natera, Inc. | Methods for nested PCR amplification of cell-free DNA |
| CN102465123B (zh) * | 2010-11-04 | 2013-06-12 | 北京金菩嘉医疗科技有限公司 | 一种核酸探针、含有该核酸探针的组合物及其用途 |
| WO2012088456A2 (en) | 2010-12-22 | 2012-06-28 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| AU2011358564B9 (en) | 2011-02-09 | 2017-07-13 | Natera, Inc | Methods for non-invasive prenatal ploidy calling |
| WO2012149339A2 (en) | 2011-04-29 | 2012-11-01 | Sequenom, Inc. | Quantification of a minority nucleic acid species |
| CN102703578B (zh) * | 2011-07-06 | 2013-12-04 | 郭奇伟 | Y染色体微缺失多重实时荧光pcr检测试剂盒 |
| CN102559872B (zh) * | 2011-12-09 | 2014-01-15 | 上海交通大学 | 检测Angelman综合征的基因芯片及使用方法、试剂盒 |
| HK1206055A1 (en) | 2012-03-02 | 2015-12-31 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| EP2852682B1 (en) | 2012-05-21 | 2017-10-04 | Fluidigm Corporation | Single-particle analysis of particle populations |
| US10504613B2 (en) | 2012-12-20 | 2019-12-10 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US9920361B2 (en) | 2012-05-21 | 2018-03-20 | Sequenom, Inc. | Methods and compositions for analyzing nucleic acid |
| US20150154352A1 (en) * | 2012-06-21 | 2015-06-04 | Gigagen, Inc. | System and Methods for Genetic Analysis of Mixed Cell Populations |
| US20140093873A1 (en) | 2012-07-13 | 2014-04-03 | Sequenom, Inc. | Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
| HK1216655A1 (zh) | 2013-03-13 | 2016-11-25 | Sequenom, Inc. | 用於dna甲基化分析的引物 |
| WO2015045741A1 (ja) * | 2013-09-26 | 2015-04-02 | 東洋鋼鈑株式会社 | ハイブリダイゼーション用バッファー組成物及びハイブリダイゼーション方法 |
| US9499870B2 (en) | 2013-09-27 | 2016-11-22 | Natera, Inc. | Cell free DNA diagnostic testing standards |
| US10577655B2 (en) | 2013-09-27 | 2020-03-03 | Natera, Inc. | Cell free DNA diagnostic testing standards |
| US10262755B2 (en) | 2014-04-21 | 2019-04-16 | Natera, Inc. | Detecting cancer mutations and aneuploidy in chromosomal segments |
| US11365447B2 (en) | 2014-03-13 | 2022-06-21 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| EP3957749A1 (en) | 2014-04-21 | 2022-02-23 | Natera, Inc. | Detecting tumour specific mutations in biopsies with whole exome sequencing and in cell-free samples |
| US12492429B2 (en) | 2014-04-21 | 2025-12-09 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| US20180173845A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| WO2016183106A1 (en) | 2015-05-11 | 2016-11-17 | Natera, Inc. | Methods and compositions for determining ploidy |
| US9422547B1 (en) | 2015-06-09 | 2016-08-23 | Gigagen, Inc. | Recombinant fusion proteins and libraries from immune cell repertoires |
| WO2017181202A2 (en) | 2016-04-15 | 2017-10-19 | Natera, Inc. | Methods for lung cancer detection |
| EP3448886A4 (en) * | 2016-04-26 | 2019-12-11 | Ultivue, Inc. | SUPER-HIGH-RESOLUTION IMMUNOFLUORESCENCE WITH BINDING-LIMITED PREVIEW |
| US11485996B2 (en) | 2016-10-04 | 2022-11-01 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
| US10894976B2 (en) | 2017-02-21 | 2021-01-19 | Natera, Inc. | Compositions, methods, and kits for isolating nucleic acids |
| EP3662480A4 (en) * | 2017-08-04 | 2021-05-19 | BillionToOne, Inc. | MOLECULES ASSOCIATED WITH A TARGET FOR A CHARACTERIZATION ASSOCIATED WITH BIOLOGICAL TARGETS |
| JP2021506342A (ja) | 2017-12-14 | 2021-02-22 | ティーエーアイ ダイアグノスティックス インコーポレイテッドＴａｉ Ｄｉａｇｎｏｓｔｉｃｓ，Ｉｎｃ． | 移植のための移植片適合性の評価 |
| US12398389B2 (en) | 2018-02-15 | 2025-08-26 | Natera, Inc. | Methods for isolating nucleic acids with size selection |
| CA3090426A1 (en) | 2018-04-14 | 2019-10-17 | Natera, Inc. | Methods for cancer detection and monitoring by means of personalized detection of circulating tumor dna |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| WO2020191365A1 (en) | 2019-03-21 | 2020-09-24 | Gigamune, Inc. | Engineered cells expressing anti-viral t cell receptors and methods of use thereof |
| EP3980559A1 (en) | 2019-06-06 | 2022-04-13 | Natera, Inc. | Methods for detecting immune cell dna and monitoring immune system |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6040138A (en) * | 1995-09-15 | 2000-03-21 | Affymetrix, Inc. | Expression monitoring by hybridization to high density oligonucleotide arrays |
| US5213961A (en) | 1989-08-31 | 1993-05-25 | Brigham And Women's Hospital | Accurate quantitation of RNA and DNA by competetitive polymerase chain reaction |
| WO1994003638A1 (en) | 1992-07-30 | 1994-02-17 | Applied Biosystems, Inc. | Method of detecting aneuploidy by amplified short tandem repeats |
| US5643765A (en) | 1993-04-06 | 1997-07-01 | University Of Rochester | Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction |
| US5639606A (en) | 1993-04-06 | 1997-06-17 | The University Of Rochester | Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction |
| JPH0723800A (ja) | 1993-07-08 | 1995-01-27 | Tanabe Seiyaku Co Ltd | 核酸の検出方法 |
| US5716784A (en) | 1996-02-05 | 1998-02-10 | The Perkin-Elmer Corporation | Fluorescence detection assay for homogeneous PCR hybridization systems |
| US5888740A (en) * | 1997-09-19 | 1999-03-30 | Genaco Biomedical Products, Inc. | Detection of aneuploidy and gene deletion by PCR-based gene- dose co-amplification of chromosome specific sequences with synthetic sequences with synthetic internal controls |
| GB9815799D0 (en) | 1998-07-21 | 1998-09-16 | Pharmagene Lab Limited | Quantitative analysis of gene expression |
| US6268147B1 (en) | 1998-11-02 | 2001-07-31 | Kenneth Loren Beattie | Nucleic acid analysis using sequence-targeted tandem hybridization |
| US6251601B1 (en) * | 1999-02-02 | 2001-06-26 | Vysis, Inc. | Simultaneous measurement of gene expression and genomic abnormalities using nucleic acid microarrays |
| US6319674B1 (en) * | 1999-09-16 | 2001-11-20 | Agilent Technologies, Inc. | Methods for attaching substances to surfaces |
| US20030054386A1 (en) * | 2001-06-22 | 2003-03-20 | Stylianos Antonarakis | Method for detecting diseases caused by chromosomal imbalances |
| EP1329517A1 (en) * | 2002-01-22 | 2003-07-23 | Wolfgang Prof. Holzgreve | Method for the non-invasive prenatal diagnosis of chromosomal and/or genetic abnormalities |
| US20050191636A1 (en) * | 2004-03-01 | 2005-09-01 | Biocept, Inc. | Detection of STRP, such as fragile X syndrome |
-
2004
- 2004-05-05 US US10/840,208 patent/US7468249B2/en not_active Expired - Fee Related
-
2005
- 2005-04-18 CN CNA2005800205301A patent/CN1981052A/zh active Pending
- 2005-04-18 AT AT05740284T patent/ATE503024T1/de active
- 2005-04-18 WO PCT/US2005/013070 patent/WO2005111237A1/en not_active Ceased
- 2005-04-18 JP JP2007511389A patent/JP5032304B2/ja not_active Expired - Fee Related
- 2005-04-18 KR KR1020067025434A patent/KR101176091B1/ko not_active Expired - Fee Related
- 2005-04-18 EP EP05740284A patent/EP1759011B1/en not_active Expired - Lifetime
- 2005-04-18 DE DE602005027067T patent/DE602005027067D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005111237A1 (en) | 2005-11-24 |
| US7468249B2 (en) | 2008-12-23 |
| JP5032304B2 (ja) | 2012-09-26 |
| KR101176091B1 (ko) | 2012-08-22 |
| KR20070031923A (ko) | 2007-03-20 |
| US20050250111A1 (en) | 2005-11-10 |
| DE602005027067D1 (de) | 2011-05-05 |
| JP2007535928A (ja) | 2007-12-13 |
| CN1981052A (zh) | 2007-06-13 |
| EP1759011B1 (en) | 2011-03-23 |
| EP1759011A1 (en) | 2007-03-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE503024T1 (de) | Nachweis chromosomaler störungen | |
| US10760123B2 (en) | Sequential sequencing | |
| Krjutškov et al. | Development of a single tube 640-plex genotyping method for detection of nucleic acid variations on microarrays | |
| JP2007535928A5 (https=) | ||
| JP2021510541A (ja) | 新規なプライマーおよびその使用 | |
| US20160068907A1 (en) | Profiling Expression at Transcriptome Scale | |
| JP2013509871A5 (https=) | ||
| RU2012109893A (ru) | Зонд td и его применения | |
| CA2528577A1 (en) | Methods and compositions for whole genome amplification and genotyping | |
| ATE288964T1 (de) | Methoden für externe kontrollen zur nukleinsäure amplifizierung | |
| WO1999040226A3 (en) | Determination of a genotype of an amplification product at multiple allelic sites | |
| RU2009146054A (ru) | Способы скрининга нуклеиновых кислот для выявления одиночных нуклеотидных вариаций | |
| EP3175236A1 (en) | Detection of target nucleic acids using hybridization | |
| CA2609017A1 (en) | Susceptibility genes for age-related maculopathy (arm) on chromosome 10q26 | |
| US20220145284A1 (en) | Method of detecting multiple targets based on single detection probe using tag sequence snp | |
| WO2020142631A3 (en) | Quantitative amplicon sequencing for multiplexed copy number variation detection and allele ratio quantitation | |
| US20150141256A1 (en) | Compositions and methods for bisulfite converted sequence capture | |
| Watanabe et al. | Evaluation of a blood-specific DNA methylated region and trial for allele-specific blood identification from mixed body fluid DNA | |
| US20210340611A1 (en) | Digital polymerase chain reaction method for detecting nucleic acids in samples | |
| US20120021949A1 (en) | Methylation Ligation-Dependent Macroarray (MLM) | |
| EP3987056A1 (en) | Methods for differentially quantifying nucleic acids | |
| JP6728556B2 (ja) | 一塩基多型検出用キット及び方法 | |
| CA2451394A1 (en) | Il-4 receptor sequence variation associated with type 1 diabetes | |
| Bavykin et al. | Discrimination of Bacillus anthracis and closely related microorganisms by analysis of 16S and 23S rRNA with oligonucleotide microarray | |
| Pack et al. | Accurate guanine: cytosine discrimination in T4 DNA ligase-based single nucleotide polymorphism analysis using an oxanine-containing ligation fragment |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1759011 Country of ref document: EP |