ATE502645T1 - Zusammensetzung für knorpel-therapeutika und anwendungsverfahren dafür - Google Patents

Zusammensetzung für knorpel-therapeutika und anwendungsverfahren dafür

Info

Publication number
ATE502645T1
ATE502645T1 AT04808335T AT04808335T ATE502645T1 AT E502645 T1 ATE502645 T1 AT E502645T1 AT 04808335 T AT04808335 T AT 04808335T AT 04808335 T AT04808335 T AT 04808335T AT E502645 T1 ATE502645 T1 AT E502645T1
Authority
AT
Austria
Prior art keywords
cartilage
therapeutic composition
thrombin
fibrinogen
human
Prior art date
Application number
AT04808335T
Other languages
English (en)
Inventor
Cheong-Ho Chang
Chang-Kwon Ko
Jae-Deog Jang
Eun-Young Lee
Jeong-Yong Choi
Original Assignee
Sewon Cellontech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sewon Cellontech Co Ltd filed Critical Sewon Cellontech Co Ltd
Application granted granted Critical
Publication of ATE502645T1 publication Critical patent/ATE502645T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37Digestive system
    • A61K35/39Pancreas; Islets of Langerhans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/225Fibrin; Fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3817Cartilage-forming cells, e.g. pre-chondrocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843Connective tissue
    • A61L27/3852Cartilage, e.g. meniscus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30756Cartilage endoprostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/06Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Vascular Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Physiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AT04808335T 2003-12-23 2004-12-07 Zusammensetzung für knorpel-therapeutika und anwendungsverfahren dafür ATE502645T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2003-0095340A KR100531922B1 (ko) 2003-12-23 2003-12-23 연골치료제 조성물 및 그 사용방법
PCT/KR2004/003204 WO2005060987A1 (en) 2003-12-23 2004-12-07 A composition for cartilage therapeutics and using method thereof

Publications (1)

Publication Number Publication Date
ATE502645T1 true ATE502645T1 (de) 2011-04-15

Family

ID=36928821

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04808335T ATE502645T1 (de) 2003-12-23 2004-12-07 Zusammensetzung für knorpel-therapeutika und anwendungsverfahren dafür

Country Status (14)

Country Link
US (1) US20070087032A1 (de)
EP (1) EP1706132B1 (de)
JP (1) JP4542106B2 (de)
KR (1) KR100531922B1 (de)
CN (1) CN1897964A (de)
AT (1) ATE502645T1 (de)
CY (1) CY1111583T1 (de)
DE (1) DE602004031979D1 (de)
DK (1) DK1706132T3 (de)
ES (1) ES2361837T3 (de)
PL (1) PL1706132T3 (de)
PT (1) PT1706132E (de)
SI (1) SI1706132T1 (de)
WO (1) WO2005060987A1 (de)

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US7622562B2 (en) * 2002-06-26 2009-11-24 Zimmer Orthobiologics, Inc. Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue
ATE515245T1 (de) 2003-12-11 2011-07-15 Isto Technologies Inc Teilchenförmiges knorpelsystem
US8512730B2 (en) 2004-07-12 2013-08-20 Isto Technologies, Inc. Methods of tissue repair and compositions therefor
KR100751690B1 (ko) * 2005-06-13 2007-08-23 세원셀론텍(주) 조골 세포와 생체 기질 성분의 혼합물을 이용한 골 생성용조성물 및 그 제조방법
KR100774089B1 (ko) 2005-07-20 2007-11-06 세원셀론텍(주) 주입형 연골세포치료제의 이식방법
EP1916964A4 (de) 2005-08-26 2015-11-04 Zimmer Inc Implantate und verfahren zur behebung, ersetzung und behandlung von gelenkkrankheiten
EP1924146A4 (de) * 2005-09-02 2012-05-02 Interface Biotech As Zellimplantationsverfahren
EP1764117A1 (de) * 2005-09-20 2007-03-21 Zimmer GmbH Implantat zur Wiederherstellung von Knorpeldefekten und Verfahren zu seiner Herstellung
US20090208464A1 (en) * 2006-01-24 2009-08-20 Centeno Christopher J Mesenchymal stem cell isolation and transplantation method and system to be used in a clinical setting
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
US20090012629A1 (en) 2007-04-12 2009-01-08 Isto Technologies, Inc. Compositions and methods for tissue repair
EP2823829B1 (de) * 2007-04-23 2016-07-20 Baxter International Inc. Fibrinzusammensetzungen mit Strontiumverbindungen zur Knochenbildung
DE602007011574D1 (de) * 2007-05-02 2011-02-10 Klinikum Mannheim Gmbh Implantierbares System für eine Bandscheibe und Bandscheibenimplantat
US9095562B2 (en) 2007-07-05 2015-08-04 Regenerative Sciences, Inc. Methods and compositions for optimized expansion and implantation of mesenchymal stem cells
US20110200642A1 (en) 2007-12-19 2011-08-18 Regenerative Sciences, Llc Compositions and Methods to Promote Implantation and Engrafment of Stem Cells
WO2009114785A2 (en) 2008-03-14 2009-09-17 Regenerative Sciences, Inc. Compositions and methods for cartilage repair
KR20100056718A (ko) * 2008-11-20 2010-05-28 한국과학기술연구원 형상회복력을 갖는 고탄성 생분해성 고분자 지지체 및 이를이용한 관절 연골 손상의 치료
CN102325536A (zh) 2008-12-05 2012-01-18 再生科学有限责任公司 促进无血管组织修复的方法和组合物
KR101114773B1 (ko) * 2009-10-23 2012-03-05 세원셀론텍(주) 연골조직 수복용 조성물의 제조방법
WO2012141536A2 (ko) * 2011-04-15 2012-10-18 가톨릭대학교 산학협력단 결합조직 재생용 조성물 및 결합조직을 재생하는 방법
EP2726603B1 (de) 2011-06-29 2020-04-01 Biorestorative Therapies, Inc. Braunfettzellenzusamensetzungen und verfahren
KR101279812B1 (ko) * 2012-05-16 2013-06-28 세원셀론텍(주) 연골조직 수복용 조성물의 제조방법
US10245306B2 (en) 2012-11-16 2019-04-02 Isto Technologies Ii, Llc Flexible tissue matrix and methods for joint repair
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
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BR112020015615B1 (pt) * 2018-01-31 2023-04-04 Rokit Healthcare Inc Composição de biotinta para regeneração de cartilagem, método para fabricar arcabouço customizado para regeneração de cartilagem usando a mesma e arcabouço customizado para regeneração de cartilagem fabricado usando o método de fabricação
CN112672717A (zh) * 2018-06-11 2021-04-16 欧酷根公司 用于关节软骨修复的带有胶粘剂的支架
CN112336751A (zh) * 2020-11-27 2021-02-09 福建华民生物科技有限公司 一种治疗软骨损伤及关节炎的药物及其配套注入装置
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Also Published As

Publication number Publication date
PT1706132E (pt) 2011-05-31
SI1706132T1 (sl) 2011-07-29
KR20050064068A (ko) 2005-06-29
EP1706132A4 (de) 2009-07-15
DK1706132T3 (da) 2011-06-14
DE602004031979D1 (de) 2011-05-05
JP2007513730A (ja) 2007-05-31
EP1706132A1 (de) 2006-10-04
US20070087032A1 (en) 2007-04-19
WO2005060987A1 (en) 2005-07-07
JP4542106B2 (ja) 2010-09-08
EP1706132B1 (de) 2011-03-23
ES2361837T3 (es) 2011-06-22
CY1111583T1 (el) 2015-10-07
KR100531922B1 (ko) 2005-11-29
PL1706132T3 (pl) 2011-09-30
CN1897964A (zh) 2007-01-17

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