ATE500821T1 - Brauseformen von opiaten zur oralen anwendung und verfahren zur verabreichung von oxycodon - Google Patents
Brauseformen von opiaten zur oralen anwendung und verfahren zur verabreichung von oxycodonInfo
- Publication number
- ATE500821T1 ATE500821T1 AT04815715T AT04815715T ATE500821T1 AT E500821 T1 ATE500821 T1 AT E500821T1 AT 04815715 T AT04815715 T AT 04815715T AT 04815715 T AT04815715 T AT 04815715T AT E500821 T1 ATE500821 T1 AT E500821T1
- Authority
- AT
- Austria
- Prior art keywords
- administration
- opiatives
- effortable
- oxycodone
- forms
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53361903P | 2003-12-31 | 2003-12-31 | |
US61566504P | 2004-10-04 | 2004-10-04 | |
US61578504P | 2004-10-04 | 2004-10-04 | |
PCT/US2004/043702 WO2005065318A2 (en) | 2003-12-31 | 2004-12-30 | Effervescent oral opiate dosage form |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE500821T1 true ATE500821T1 (de) | 2011-03-15 |
Family
ID=34753692
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04815715T ATE500821T1 (de) | 2003-12-31 | 2004-12-30 | Brauseformen von opiaten zur oralen anwendung und verfahren zur verabreichung von oxycodon |
Country Status (16)
Country | Link |
---|---|
US (2) | US7862833B2 (xx) |
EP (1) | EP1708685B1 (xx) |
JP (2) | JP5244318B2 (xx) |
KR (1) | KR101212437B1 (xx) |
AT (1) | ATE500821T1 (xx) |
AU (1) | AU2004311879B2 (xx) |
BR (1) | BRPI0418213A (xx) |
CA (1) | CA2549642C (xx) |
DE (1) | DE602004031771D1 (xx) |
HK (1) | HK1100166A1 (xx) |
IL (1) | IL176452A (xx) |
MX (1) | MXPA06007453A (xx) |
NO (1) | NO338567B1 (xx) |
NZ (1) | NZ548215A (xx) |
WO (1) | WO2005065318A2 (xx) |
ZA (1) | ZA200606173B (xx) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6974590B2 (en) * | 1998-03-27 | 2005-12-13 | Cima Labs Inc. | Sublingual buccal effervescent |
US20030091629A1 (en) * | 1998-03-27 | 2003-05-15 | Cima Labs Inc. | Sublingual buccal effervescent |
US20030118645A1 (en) * | 1998-04-29 | 2003-06-26 | Pather S. Indiran | Pharmaceutical compositions for rectal and vaginal administration |
US20030068356A1 (en) * | 2001-07-10 | 2003-04-10 | Pather S. Indiran | Sequential drug delivery systems |
WO2005065319A2 (en) * | 2003-12-31 | 2005-07-21 | Cima Labs Inc. | Generally linear effervescent oral fentanyl dosage form and methods of administering |
US7858121B2 (en) | 2003-12-31 | 2010-12-28 | Cima Labs, Inc. | Effervescent oral fentanyl dosage form and methods of administering fentanyl |
AU2004311879B2 (en) * | 2003-12-31 | 2010-08-05 | Cima Labs Inc. | Effervescent oral opiate dosage form |
US8865743B2 (en) | 2006-01-06 | 2014-10-21 | Acelrx Pharmaceuticals, Inc. | Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain |
US8535714B2 (en) | 2006-01-06 | 2013-09-17 | Acelrx Pharmaceuticals, Inc. | Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain |
US8357114B2 (en) | 2006-01-06 | 2013-01-22 | Acelrx Pharmaceuticals, Inc. | Drug dispensing device with flexible push rod |
US8753308B2 (en) | 2006-01-06 | 2014-06-17 | Acelrx Pharmaceuticals, Inc. | Methods for administering small volume oral transmucosal dosage forms using a dispensing device |
US8252328B2 (en) * | 2006-01-06 | 2012-08-28 | Acelrx Pharmaceuticals, Inc. | Bioadhesive drug formulations for oral transmucosal delivery |
US8252329B2 (en) | 2007-01-05 | 2012-08-28 | Acelrx Pharmaceuticals, Inc. | Bioadhesive drug formulations for oral transmucosal delivery |
US8202535B2 (en) | 2006-01-06 | 2012-06-19 | Acelrx Pharmaceuticals, Inc. | Small-volume oral transmucosal dosage forms |
US9066847B2 (en) * | 2007-01-05 | 2015-06-30 | Aceirx Pharmaceuticals, Inc. | Storage and dispensing devices for administration of oral transmucosal dosage forms |
US9289583B2 (en) | 2006-01-06 | 2016-03-22 | Acelrx Pharmaceuticals, Inc. | Methods for administering small volume oral transmucosal dosage forms using a dispensing device |
US20070260491A1 (en) * | 2006-05-08 | 2007-11-08 | Pamela Palmer | System for delivery and monitoring of administration of controlled substances |
US20070299687A1 (en) * | 2006-06-23 | 2007-12-27 | Pamela Palmer | Inpatient system for patient-controlled delivery of oral transmucosal medications dosed as needed |
US20080090874A1 (en) * | 2006-09-20 | 2008-04-17 | Messina John C Jr | Treatment of breakthrough pain in patients suffering from chronic low back pain |
US20090214442A1 (en) * | 2006-12-01 | 2009-08-27 | Cephalon, Inc. | Oral Transmucosal Nicotine Dosage Form |
WO2008069921A2 (en) * | 2006-12-01 | 2008-06-12 | Cima Labs Inc. | Oral transmucosal nicotine dosage form |
US20080287494A1 (en) * | 2007-04-24 | 2008-11-20 | Cephalon, Inc. | Transmucosal treatment methods in patients with mucositis |
AU2008248228B2 (en) | 2007-05-01 | 2012-10-18 | Cephalon, Inc. | Composition for transmucosal delivery of polypeptides |
US8945592B2 (en) | 2008-11-21 | 2015-02-03 | Acelrx Pharmaceuticals, Inc. | Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same |
DK2442650T3 (en) | 2009-06-12 | 2015-12-07 | Cynapsus Therapeutics Inc | sublingual apomorphine |
NZ612686A (en) | 2010-12-16 | 2015-11-27 | Cynapsus Therapeutics Inc | Sublingual films |
CA2853764C (en) * | 2011-11-22 | 2017-05-16 | Watson Pharmaceuticals, Inc. | Immediate release abuse deterrent tablet |
PL2849730T3 (pl) | 2012-05-02 | 2017-05-31 | Orexo Ab | Nowa kompozycja zawierająca alfentanyl do leczenia ostrego bólu |
MX362838B (es) | 2012-07-12 | 2019-02-19 | SpecGx LLC | Composiciones farmacéuticas de liberación prolongada para disuadir el abuso de opioides que comprenden un plastómero, un elastómero y un plastificante delicuescente. |
JP5988936B2 (ja) * | 2013-09-04 | 2016-09-07 | 富士フイルム株式会社 | 撥水膜、成膜方法、ノズルプレート、インクジェットヘッド、及びインクジェット記録装置 |
MX2017008428A (es) | 2014-12-23 | 2018-03-23 | Acelrx Pharmaceuticals Inc | Sistemas, dispositivos y métodos para dispensar formas de dosificación transmucosa oral. |
JP7211706B2 (ja) | 2015-04-21 | 2023-01-24 | サノヴィオン ファーマシュティカルズ インコーポレーテッド | 口腔粘膜へのアポモルフィンの投与によるパーキンソン病の治療方法 |
US9943513B1 (en) | 2015-10-07 | 2018-04-17 | Banner Life Sciences Llc | Opioid abuse deterrent dosage forms |
US10335405B1 (en) | 2016-05-04 | 2019-07-02 | Patheon Softgels, Inc. | Non-burst releasing pharmaceutical composition |
NO20171457A1 (no) * | 2016-12-20 | 2018-06-21 | X Ing As | Effervesent sugetablett |
US10335375B2 (en) | 2017-05-30 | 2019-07-02 | Patheon Softgels, Inc. | Anti-overingestion abuse deterrent compositions |
Family Cites Families (128)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1262888A (en) | 1917-02-20 | 1918-04-16 | Albert Westlake | Mouth-tablet. |
US1263888A (en) | 1918-01-10 | 1918-04-23 | J T Vail | Wave-motor. |
US2887437A (en) * | 1956-08-22 | 1959-05-19 | Pfizer & Co C | Palatable vitamin tablet containing an amino acid |
US3131123A (en) | 1959-03-13 | 1964-04-28 | Lab Francais De Therapeutique | Enteric tablets and manufacture thereof |
US3042531A (en) * | 1959-12-09 | 1962-07-03 | Leslie Salt Company | Method of making a compressed tablet |
US3577490A (en) | 1967-10-02 | 1971-05-04 | Miles Lab | Effervescent tablet and process for making same |
GB1212704A (en) | 1967-11-21 | 1970-11-18 | Prodotti Antibiotici Spa | Vaginal suppositories |
US3888976A (en) | 1972-09-21 | 1975-06-10 | William P Mlkvy | Zinc and strontium ion containing effervescent mouthwash tablet |
NL7302521A (en) | 1973-02-23 | 1974-08-27 | Foaming, effervescent capsules - contg. therapeutic agents for rectal and vaginal use | |
US3962417A (en) | 1974-03-27 | 1976-06-08 | Howell Charles J | Dentifrice |
JPS5157813A (en) | 1974-11-14 | 1976-05-20 | Sankyo Co | Ll dooba mataha sonojudotaiseizaino seiho |
US3972995A (en) | 1975-04-14 | 1976-08-03 | American Home Products Corporation | Dosage form |
US4126684A (en) * | 1976-02-11 | 1978-11-21 | Ciba-Geigy Corporation | 4-amino-3-p-halophenylbutyric acids and their derivatives used in the control of narcotic abuse |
US4147768A (en) | 1976-09-13 | 1979-04-03 | Interx Research Corporation | Enteric coated digoxin and therapeutic use thereof |
US4370160A (en) * | 1978-06-27 | 1983-01-25 | Dow Corning Corporation | Process for preparing silicone microparticles |
US4187286A (en) | 1979-01-02 | 1980-02-05 | G&W Laboratories, Inc. | Contraceptive suppository |
US4289751A (en) | 1979-06-29 | 1981-09-15 | Merck & Co., Inc. | Effervescent enteric-coated formulation of soluble form of erythromycin and therapeutic use thereof |
JPS58152809A (ja) | 1982-03-05 | 1983-09-10 | Eisai Co Ltd | 安定な発泡性「膣」坐剤 |
US4443428A (en) | 1982-06-21 | 1984-04-17 | Euroceltique, S.A. | Extended action controlled release compositions |
US4503031A (en) | 1982-12-17 | 1985-03-05 | Glassman Jacob A | Super-fast-starting-sustained release tablet |
US4493848A (en) | 1983-07-14 | 1985-01-15 | The Procter & Gamble Company | Compositions and methods useful for producing analgesia |
US4599342A (en) | 1984-01-16 | 1986-07-08 | The Procter & Gamble Company | Pharmaceutical products providing enhanced analgesia |
GB8410290D0 (en) | 1984-04-19 | 1984-05-31 | Callingham B A | Pharmaceutical compositions |
US4613497A (en) | 1984-02-29 | 1986-09-23 | Health Products Development, Inc. | Dry, water-foamable pharmaceutical compositions |
US4725427A (en) | 1984-03-13 | 1988-02-16 | Albion International, Inc. | Effervescent vitamin-mineral granule preparation |
US4863737A (en) | 1985-05-01 | 1989-09-05 | University Of Utah | Compositions and methods of manufacture of compressed powder medicaments |
GB8421226D0 (en) | 1984-08-21 | 1984-09-26 | Int Conferences Ab | Tooth cleaning tablet |
US4639368A (en) | 1984-08-23 | 1987-01-27 | Farmacon Research Corporation | Chewing gum containing a medicament and taste maskers |
GB8426152D0 (en) * | 1984-10-16 | 1984-11-21 | Reckitt & Colmann Prod Ltd | Medicinal compositions |
IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
US4756710A (en) | 1985-04-05 | 1988-07-12 | Merck & Co., Inc. | pH-Mediated drug delivery system |
US4671953A (en) | 1985-05-01 | 1987-06-09 | University Of Utah Research Foundation | Methods and compositions for noninvasive administration of sedatives, analgesics, and anesthetics |
US5288497A (en) * | 1985-05-01 | 1994-02-22 | The University Of Utah | Compositions of oral dissolvable medicaments |
US5785989A (en) | 1985-05-01 | 1998-07-28 | University Utah Research Foundation | Compositions and methods of manufacturing of oral dissolvable medicaments |
US4687662A (en) | 1985-08-30 | 1987-08-18 | Warner-Lambert Company | Therapeutic effervescent composition |
US5053396A (en) | 1985-08-27 | 1991-10-01 | Blass David H | Therapeutic composition |
US4764375A (en) | 1985-09-11 | 1988-08-16 | Kv Pharmaceutical Company | Sachet drug delivery system |
IT1209667B (it) | 1985-11-12 | 1989-08-30 | Zambon Spa | Composizione effeverscente adattivita' analgesica. |
US4876039A (en) * | 1986-11-04 | 1989-10-24 | Dow Corning Corporation | Process for preparing silicone microparticles cured by a Michael addition reaction |
IE873172L (en) | 1986-12-29 | 1988-06-29 | Harvard College | Continuous process for producing a comestible tablet |
GB8724763D0 (en) | 1987-10-22 | 1987-11-25 | Aps Research Ltd | Sustained-release formulations |
US5234957A (en) * | 1991-02-27 | 1993-08-10 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
FR2633181B1 (fr) * | 1988-06-24 | 1992-01-10 | Glaxo Lab Sa | Composition pharmaceutique a base de ranitidine et son procede de preparation |
GB8820327D0 (en) * | 1988-08-26 | 1988-09-28 | May & Baker Ltd | New compositions of matter |
US5004601A (en) * | 1988-10-14 | 1991-04-02 | Zetachron, Inc. | Low-melting moldable pharmaceutical excipient and dosage forms prepared therewith |
US5135752A (en) | 1988-10-14 | 1992-08-04 | Zetachron, Inc. | Buccal dosage form |
DE3838431A1 (de) | 1988-11-12 | 1990-05-17 | Bayer Ag | Ibuprofen-brausezubereitungen |
US5073374A (en) * | 1988-11-30 | 1991-12-17 | Schering Corporation | Fast dissolving buccal tablet |
US5002771A (en) | 1989-02-06 | 1991-03-26 | Rorer Pharmaceutical Corp. | Calcitonin suppository formulations |
GB8909793D0 (en) | 1989-04-28 | 1989-06-14 | Beecham Group Plc | Pharmaceutical formulation |
US5223264A (en) | 1989-10-02 | 1993-06-29 | Cima Labs, Inc. | Pediatric effervescent dosage form |
US5178878A (en) | 1989-10-02 | 1993-01-12 | Cima Labs, Inc. | Effervescent dosage form with microparticles |
IT1246382B (it) | 1990-04-17 | 1994-11-18 | Eurand Int | Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon |
US5102666A (en) | 1990-09-11 | 1992-04-07 | Oramed, Inc. | Calcium polycarbophil controlled release composition and method |
US5468504A (en) | 1990-12-21 | 1995-11-21 | Laboratoires Glaxo S.A. | Effervescent pharmaceutical compositions |
TW212139B (xx) | 1991-04-15 | 1993-09-01 | Yamanouchi Pharma Co Ltd | |
US5559096A (en) | 1991-04-15 | 1996-09-24 | Applied Microbiology, Inc. | Pharmaceutical compositions against gastric disorders |
US5464632C1 (en) | 1991-07-22 | 2001-02-20 | Prographarm Lab | Rapidly disintegratable multiparticular tablet |
IT1251114B (it) | 1991-07-26 | 1995-05-04 | Farcon Ag | Forme farmaceutiche antivirali per applicazione vaginale |
IT1253711B (it) | 1991-12-17 | 1995-08-23 | Alfa Wassermann Spa | Formulazioni farmaceutiche vaginali contenenti rifaximin e loro uso nel trattamento delle infezioni vaginali |
JP3069458B2 (ja) | 1992-01-29 | 2000-07-24 | 武田薬品工業株式会社 | 口腔内崩壊型錠剤およびその製造法 |
US5503846A (en) | 1993-03-17 | 1996-04-02 | Cima Labs, Inc. | Base coated acid particles and effervescent formulation incorporating same |
US5851553A (en) | 1993-09-10 | 1998-12-22 | Fuisz Technologies, Ltd. | Process and apparatus for making rapidly dissolving dosage units and product therefrom |
US5635210A (en) * | 1994-02-03 | 1997-06-03 | The Board Of Regents Of The University Of Oklahoma | Method of making a rapidly dissolving tablet |
US5458879A (en) * | 1994-03-03 | 1995-10-17 | The Procter & Gamble Company | Oral vehicle compositions |
WO1995024172A1 (en) | 1994-03-07 | 1995-09-14 | Theratech, Inc. | Drug-containing adhesive composite transdermal delivery device |
CA2185803C (en) | 1994-03-18 | 2006-07-11 | Edward M. Rudnic | Emulsified drug delivery systems |
IE940292A1 (en) | 1994-04-06 | 1995-10-18 | Elan Corp Plc | Biodegradable microcapsules and method for their manufacture |
JP3170139B2 (ja) | 1994-04-08 | 2001-05-28 | エスエス製薬株式会社 | 発泡性錠剤 |
EP0755244A1 (en) | 1994-04-13 | 1997-01-29 | Novartis AG | Temporally controlled drug delivery systems |
AU697456B2 (en) | 1994-06-15 | 1998-10-08 | Dumex-Alpharma A/S | Pellets |
US5958458A (en) | 1994-06-15 | 1999-09-28 | Dumex-Alpharma A/S | Pharmaceutical multiple unit particulate formulation in the form of coated cores |
GB9417524D0 (en) | 1994-08-31 | 1994-10-19 | Cortecs Ltd | Pharmaceutical compositions |
US5550861A (en) * | 1994-09-27 | 1996-08-27 | Novalink Technologies, Inc. | Modular PCMCIA modem and pager |
CA2160423A1 (en) | 1994-11-02 | 1996-05-03 | Hemant N. Joshi | Salts of nefazodone having improved dissolution rates |
FR2729858B1 (fr) | 1995-01-30 | 1997-04-18 | Mission Soc Civ | Composition effervescente a base de polyvinylpyrrolidone iodee et utilisation pour la desinfection |
FR2732217B1 (fr) | 1995-03-29 | 1997-06-06 | Hesnard Xavier | Forme d'administration solide a usage oral |
US5656284A (en) | 1995-04-24 | 1997-08-12 | Balkin; Michael S. | Oral transmucosal delivery tablet and method of making it |
GB9510830D0 (en) | 1995-05-27 | 1995-07-19 | Zeneca Ltd | Proteins |
US5607697A (en) | 1995-06-07 | 1997-03-04 | Cima Labs, Incorporated | Taste masking microparticles for oral dosage forms |
CA2218370C (en) | 1995-07-31 | 2006-10-03 | Gerhard Gergely | Chewable tablet with effervescent action |
GB9517062D0 (en) | 1995-08-18 | 1995-10-25 | Scherer Ltd R P | Pharmaceutical compositions |
WO1997017067A1 (en) | 1995-11-06 | 1997-05-15 | Somerset Pharmaceuticals, Inc. | Sublingual and buccal administration of selegiline |
GB9523136D0 (en) | 1995-11-11 | 1996-01-10 | Procter & Gamble | Silicone-containing powders |
GB2307857B (en) | 1995-12-04 | 1999-01-27 | Euro Celtique Sa | An effervescent formulation |
US5958455A (en) | 1996-02-09 | 1999-09-28 | Quadrant Holdings Cambridge Ltd | Oral solid dosage forms, methods of making same and compositions thereof |
DE19606151C2 (de) * | 1996-02-20 | 1999-05-12 | Losan Pharma Gmbh | Ibuprofen-Brausezubereitung sowie Verfahren zur Herstellung derselben |
US5646151A (en) | 1996-03-08 | 1997-07-08 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
US5853759A (en) | 1996-05-17 | 1998-12-29 | Merck & Co.. Inc. | Effervescent alendronate formulation |
AU712710B2 (en) | 1996-05-17 | 1999-11-11 | Merck Sharp & Dohme Corp. | Effervescent bisphosphonate formulation |
US5914129A (en) * | 1996-07-23 | 1999-06-22 | Mauskop; Alexander | Analgesic composition for treatment of migraine headaches |
US6071539A (en) | 1996-09-20 | 2000-06-06 | Ethypharm, Sa | Effervescent granules and methods for their preparation |
US6488961B1 (en) | 1996-09-20 | 2002-12-03 | Ethypharm, Inc. | Effervescent granules and methods for their preparation |
US6649186B1 (en) * | 1996-09-20 | 2003-11-18 | Ethypharm | Effervescent granules and methods for their preparation |
US20010006677A1 (en) | 1996-10-29 | 2001-07-05 | Mcginity James W. | Effervescence polymeric film drug delivery system |
DE69838393T2 (de) | 1997-04-01 | 2008-01-17 | Cima Labs Inc., Eden Prairie | Blisterverpackung für tabletten |
US6024981A (en) | 1997-04-16 | 2000-02-15 | Cima Labs Inc. | Rapidly dissolving robust dosage form |
FR2766089B1 (fr) | 1997-07-21 | 2000-06-02 | Prographarm Lab | Comprime multiparticulaire perfectionne a delitement rapide |
ES2173364T5 (es) * | 1997-10-27 | 2005-04-16 | DR. GERGELY & CO. | Composicion efervescente con extracto vegetal. |
JP4372347B2 (ja) | 1998-03-11 | 2009-11-25 | あすか製薬株式会社 | 発泡性腸溶製剤 |
US20030118645A1 (en) | 1998-04-29 | 2003-06-26 | Pather S. Indiran | Pharmaceutical compositions for rectal and vaginal administration |
US6974590B2 (en) | 1998-03-27 | 2005-12-13 | Cima Labs Inc. | Sublingual buccal effervescent |
US6200604B1 (en) * | 1998-03-27 | 2001-03-13 | Cima Labs Inc. | Sublingual buccal effervescent |
US20030091629A1 (en) | 1998-03-27 | 2003-05-15 | Cima Labs Inc. | Sublingual buccal effervescent |
US6576250B1 (en) | 1998-03-27 | 2003-06-10 | Cima Labs Inc. | Pharmaceutical compositions for rectal and vaginal administration |
US6350470B1 (en) | 1998-04-29 | 2002-02-26 | Cima Labs Inc. | Effervescent drug delivery system for oral administration |
DE19814257A1 (de) | 1998-03-31 | 1999-10-07 | Asta Medica Ag | Brauseformulierungen |
US6368625B1 (en) | 1998-08-12 | 2002-04-09 | Cima Labs Inc. | Orally disintegrable tablet forming a viscous slurry |
SE9803239D0 (sv) | 1998-09-24 | 1998-09-24 | Diabact Ab | Composition for the treatment of acute pain |
SE9803240D0 (sv) | 1998-09-24 | 1998-09-24 | Diabact Ab | A pharmaceutical composition having a rapid action |
US6680071B1 (en) | 1999-03-03 | 2004-01-20 | R. P. Scherer Technologies, Inc. | Opioid agonist in a fast dispersing dosage form |
US6835194B2 (en) * | 1999-03-18 | 2004-12-28 | Durect Corporation | Implantable devices and methods for treatment of pain by delivery of fentanyl and fentanyl congeners |
US6210699B1 (en) * | 1999-04-01 | 2001-04-03 | Watson Pharmaceuticals, Inc. | Oral transmucosal delivery of drugs or any other ingredients via the inner buccal cavity |
US6326384B1 (en) | 1999-08-26 | 2001-12-04 | Robert R. Whittle | Dry blend pharmaceutical unit dosage form |
US6264981B1 (en) | 1999-10-27 | 2001-07-24 | Anesta Corporation | Oral transmucosal drug dosage using solid solution |
US6262062B1 (en) * | 2000-08-15 | 2001-07-17 | Cpd, Llc | Method of treating the syndrome of coronary heart disease risk factors in humans |
WO2002045713A2 (en) * | 2000-12-04 | 2002-06-13 | Sepracor, Inc. | Orally-bioavailable formulations of fentanyl and congeners thereof |
US20030035839A1 (en) * | 2001-05-15 | 2003-02-20 | Peirce Management, Llc | Pharmaceutical composition for both intraoral and oral administration |
US20030068356A1 (en) * | 2001-07-10 | 2003-04-10 | Pather S. Indiran | Sequential drug delivery systems |
EP1587514B3 (en) | 2003-01-31 | 2011-06-22 | Orexo AB | A rapid-acting pharmaceutical composition |
US20050042281A1 (en) * | 2003-08-21 | 2005-02-24 | Singh Nikhilesh N. | Compositions for delivering therapeutic agents across the oral mucosa |
US20070036853A1 (en) | 2003-12-31 | 2007-02-15 | Cima Labs Inc. | Generally linear effervescent oral fentanyl dosage form and methods of administering |
AU2004311879B2 (en) * | 2003-12-31 | 2010-08-05 | Cima Labs Inc. | Effervescent oral opiate dosage form |
US7858121B2 (en) | 2003-12-31 | 2010-12-28 | Cima Labs, Inc. | Effervescent oral fentanyl dosage form and methods of administering fentanyl |
WO2005065319A2 (en) * | 2003-12-31 | 2005-07-21 | Cima Labs Inc. | Generally linear effervescent oral fentanyl dosage form and methods of administering |
TWI387466B (zh) | 2004-10-04 | 2013-03-01 | Cima Labs Inc | 一般線型起泡的口服吩坦尼(fentanyl)劑型及投藥方法 |
FR2883179B1 (fr) * | 2005-03-18 | 2009-04-17 | Ethypharm Sa | Comprime enrobe |
US20090263476A1 (en) * | 2008-04-16 | 2009-10-22 | Jobdevairakkam Christopher N | Composition of Rapid Disintegrating Direct Compression Buccal Tablet |
-
2004
- 2004-12-30 AU AU2004311879A patent/AU2004311879B2/en active Active
- 2004-12-30 MX MXPA06007453A patent/MXPA06007453A/es active IP Right Grant
- 2004-12-30 WO PCT/US2004/043702 patent/WO2005065318A2/en active Application Filing
- 2004-12-30 JP JP2006547498A patent/JP5244318B2/ja active Active
- 2004-12-30 NZ NZ548215A patent/NZ548215A/xx unknown
- 2004-12-30 US US11/026,759 patent/US7862833B2/en active Active
- 2004-12-30 BR BRPI0418213-8A patent/BRPI0418213A/pt not_active Application Discontinuation
- 2004-12-30 DE DE602004031771T patent/DE602004031771D1/de active Active
- 2004-12-30 CA CA2549642A patent/CA2549642C/en active Active
- 2004-12-30 AT AT04815715T patent/ATE500821T1/de not_active IP Right Cessation
- 2004-12-30 EP EP04815715A patent/EP1708685B1/en active Active
-
2006
- 2006-06-20 IL IL176452A patent/IL176452A/en active IP Right Grant
- 2006-07-25 NO NO20063429A patent/NO338567B1/no unknown
- 2006-07-26 ZA ZA2006/06173A patent/ZA200606173B/en unknown
- 2006-07-28 KR KR1020067015395A patent/KR101212437B1/ko active IP Right Grant
-
2007
- 2007-05-29 HK HK07105662.9A patent/HK1100166A1/xx unknown
-
2010
- 2010-11-29 US US12/955,439 patent/US8298577B2/en active Active
-
2013
- 2013-02-12 JP JP2013024651A patent/JP5685611B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
ZA200606173B (en) | 2008-01-08 |
WO2005065318A2 (en) | 2005-07-21 |
AU2004311879B2 (en) | 2010-08-05 |
BRPI0418213A (pt) | 2007-04-27 |
HK1100166A1 (en) | 2007-09-07 |
EP1708685A4 (en) | 2007-12-26 |
US20110071181A1 (en) | 2011-03-24 |
KR101212437B1 (ko) | 2012-12-14 |
JP2007517053A (ja) | 2007-06-28 |
WO2005065318A3 (en) | 2005-12-15 |
KR20060127945A (ko) | 2006-12-13 |
MXPA06007453A (es) | 2007-01-31 |
JP2013121983A (ja) | 2013-06-20 |
US7862833B2 (en) | 2011-01-04 |
NZ548215A (en) | 2009-08-28 |
JP5685611B2 (ja) | 2015-03-18 |
CA2549642C (en) | 2012-10-30 |
US8298577B2 (en) | 2012-10-30 |
EP1708685A2 (en) | 2006-10-11 |
NO338567B1 (no) | 2016-09-05 |
EP1708685B1 (en) | 2011-03-09 |
IL176452A (en) | 2014-12-31 |
JP5244318B2 (ja) | 2013-07-24 |
IL176452A0 (en) | 2006-10-05 |
US20050163838A1 (en) | 2005-07-28 |
CA2549642A1 (en) | 2005-07-21 |
NO20063429L (no) | 2006-09-28 |
AU2004311879A1 (en) | 2005-07-21 |
DE602004031771D1 (de) | 2011-04-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE500821T1 (de) | Brauseformen von opiaten zur oralen anwendung und verfahren zur verabreichung von oxycodon | |
DE602004031462D1 (de) | Allgemein lineare brauseform von fentanyl zur oralen anwendung und verfahren zur verabreichung | |
WO2005107726A3 (en) | Method for the treatment of back pain | |
ATE450251T1 (de) | Liposomale formulierungen mit dihydrosphingomyelin und verfahren zu ihrer verwendung | |
CY1106386T1 (el) | Υποκατεστημενα παραγωγα 3-πυρρολιδιν-ινδολης | |
WO2005009370A3 (en) | Beta-carboline compounds and analogues thereof and their use as mitogen-activated protein kinase-activated protein kinase-2 inhibitors | |
DE60329729D1 (de) | Implantierbare Vorrichtung zur Arzneimittelverabreichung | |
CY1118179T1 (el) | Φαρμακευτικη συνθεση | |
DE602004027936D1 (de) | Tocopherolmodifizierte therapeutische arzneimittelverbindung | |
IL169886A0 (en) | Method for producing an immediately decomposing oral form of administration which releases active ingredients | |
CY1109962T1 (el) | Υποκατεστημενες ενωσεις 1,4,8-τριαζασπειρο[4,5]δεκαν-2-ονης για τη θεραπεια παχυσαρκιας | |
CY1113116T1 (el) | Υποκατεστημενες 4-αμινοκυκλοεξανολες | |
CY1109366T1 (el) | Υποκατεστημενες ενωσεις 1,4,8-τριαζασπειρο[4.5]δεκαν-2-ονης | |
EA200401515A1 (ru) | Новые фармацевтические композиции, содержащие флибансерин в полиморфной модификации а | |
IS6558A (is) | Blandaðar sjúkdómsmeðferðir með æðaskaðandi virkni | |
EA200700403A1 (ru) | ТРИЦИКЛИЧЕСКИЕ δ-ОПИОИДНЫЕ МОДУЛЯТОРЫ | |
CY1107231T1 (el) | Υποκατεστημενα παραγωγα 4-αμινοκυκλοεξανολης | |
DE60202603D1 (de) | 8-(c-beta-d-glucopyranosyl)-7,3',4'-trihydroxyflavone, verfahren zur isolation aus pterocarpus marsupium und pharmazeutische zusammensetzung zur behandlung von diabetes | |
WO2004073615A8 (en) | Deazaflavin compounds and methods of use thereof | |
ATE405293T1 (de) | Selbstemulgierende und selbstmicroemulgierende formulierungen zur oralen verabreichung von taxoiden | |
DE60130659D1 (de) | Therapeutische verbindungen und verfahren | |
DK1537132T3 (da) | Salt af mortin-6-glucuronid | |
TW200611686A (en) | Effervescent oral opiate dosage forms and methods of administering opiates | |
ATE302183T1 (de) | Indenoindolin derivate, verfahren zur herstellung dieser derivate und diese enthaltende pharmazeutische präparate | |
ATE513834T1 (de) | Verfahren zur herstellung von (s)-(+)- clopidogrelbase und deren salzen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |