ATE405293T1 - Selbstemulgierende und selbstmicroemulgierende formulierungen zur oralen verabreichung von taxoiden - Google Patents

Selbstemulgierende und selbstmicroemulgierende formulierungen zur oralen verabreichung von taxoiden

Info

Publication number
ATE405293T1
ATE405293T1 AT04741330T AT04741330T ATE405293T1 AT E405293 T1 ATE405293 T1 AT E405293T1 AT 04741330 T AT04741330 T AT 04741330T AT 04741330 T AT04741330 T AT 04741330T AT E405293 T1 ATE405293 T1 AT E405293T1
Authority
AT
Austria
Prior art keywords
self
microemulsifiing
emulsifiing
taxoids
formulations
Prior art date
Application number
AT04741330T
Other languages
English (en)
Inventor
Maria-Teresa Peracchia
Sophie Cote
Gilbert Gaudel
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of ATE405293T1 publication Critical patent/ATE405293T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT04741330T 2003-07-18 2004-07-15 Selbstemulgierende und selbstmicroemulgierende formulierungen zur oralen verabreichung von taxoiden ATE405293T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03291798A EP1498143A1 (de) 2003-07-18 2003-07-18 Selbstemulgierende und selbstmicroemulgierende Formulierungen zur oralen Verabreichung von Taxoiden

Publications (1)

Publication Number Publication Date
ATE405293T1 true ATE405293T1 (de) 2008-09-15

Family

ID=33462261

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04741330T ATE405293T1 (de) 2003-07-18 2004-07-15 Selbstemulgierende und selbstmicroemulgierende formulierungen zur oralen verabreichung von taxoiden

Country Status (17)

Country Link
US (2) US20050025792A1 (de)
EP (2) EP1498143A1 (de)
JP (1) JP2009513557A (de)
KR (1) KR20060052834A (de)
CN (1) CN100566758C (de)
AR (1) AR045911A1 (de)
AT (1) ATE405293T1 (de)
AU (1) AU2004262495B2 (de)
BR (1) BRPI0412740A (de)
CA (1) CA2532566A1 (de)
DE (1) DE602004015994D1 (de)
HK (1) HK1089951A1 (de)
IL (1) IL173112A0 (de)
MX (1) MXPA06000633A (de)
MY (1) MY139106A (de)
TW (1) TWI337870B (de)
WO (1) WO2005014048A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006112541A1 (ja) * 2005-04-20 2006-10-26 Chugai Seiyaku Kabushiki Kaisya 自己乳化型製剤処方の設計方法
ES2336575T3 (es) 2005-09-22 2010-04-14 Biocompatibles Uk Limited Polipeptidos de fusion glp-1 (peptido-1 similar al glucagon) con resistencia aumentada a la peptidasa.
FR2922107B1 (fr) * 2007-10-10 2010-02-26 Aventis Pharma Sa Nouvelles compositions a base de taxoides
CA2742388C (en) * 2007-11-08 2019-02-19 Virginia Tech Intellectual Properties, Inc. Thiolated paclitaxels for reaction with gold nanoparticles as drug delivery agents
CN101829052B (zh) * 2010-03-16 2011-12-14 王国强 紫杉烷类化合物的自乳化制剂及其制备方法
CN102228431A (zh) * 2010-03-16 2011-11-02 王国强 紫杉烷类化合物的自乳化药物组合物
MX341082B (es) 2010-05-03 2016-08-08 Teikoku Pharma Usa Inc Formulaciones de pro-emulsion de taxano no acuosas y metodos para hacer y usar las mismas.
JP2013209294A (ja) * 2010-07-30 2013-10-10 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 液状医薬組成物
GB2488788B (en) * 2011-03-07 2013-07-10 Natco Pharma Ltd Oral formulation of phenylaminopyrymidine compound with enhanced bioavailability and pharmacological response
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
KR101542364B1 (ko) * 2014-10-31 2015-08-07 대화제약 주식회사 탁산을 포함하는 경구 투여용 약학 조성물
TWI752750B (zh) * 2015-09-30 2022-01-11 香港商慧源香港創新有限公司 口服紫杉烷組合物及方法
CN109589305B (zh) * 2018-12-03 2021-03-19 昆明积大制药股份有限公司 多西他赛-环孢素a共包载自乳化制剂及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698582A (en) * 1991-07-08 1997-12-16 Rhone-Poulenc Rorer S.A. Compositions containing taxane derivatives
EP0746331B1 (de) * 1992-10-16 2000-09-13 IBAH, Inc. Konvertierbare mikroemulsionsformulierungen
EP0684834A4 (de) * 1993-02-17 1996-09-25 Smithkline Beecham Corp Mikroemulsionen, die therapeutische peptide enthalten.
US6964946B1 (en) * 1995-10-26 2005-11-15 Baker Norton Pharmaceuticals, Inc. Oral pharmaceutical compositions containing taxanes and methods of treatment employing the same
BE1011216A3 (fr) * 1997-06-13 1999-06-01 Thissen En Abrege L T B Lab Forme pharmaceutique pour l'administration de paclitaxel, procede de preparation d'une composition de paclitaxel prete a l'emploi et utilisation de cette composition.
AU756752B2 (en) * 1998-04-01 2003-01-23 Skyepharma Canada Inc. Anticancer compositions
CA2302735A1 (en) * 1998-07-14 2000-01-27 Em Industries, Inc. Microdisperse drug delivery systems
IL143580A0 (en) * 1998-12-11 2002-04-21 Pharmasolutions Inc Pharmaceutical compositions containing lipophilic drugs and methods for the preparation thereof
US6267985B1 (en) * 1999-06-30 2001-07-31 Lipocine Inc. Clear oil-containing pharmaceutical compositions
DE19925211B4 (de) * 1999-06-01 2006-01-12 PBS Pharmaceutical Bulk Substances SA Kit zur Herstellung einer Formulierung von Paclitaxel
AU7638300A (en) * 1999-10-20 2001-04-30 Vesifact Ag Microemulsion preconcentrates and microemulsions
EP1365759A2 (de) * 2001-01-18 2003-12-03 PHARMACIA & UPJOHN COMPANY Paclitaxel-enthaltende chemotherapeutische mikroemulsionen mit verbesserter oraler bioverfügbarkeit
US20020192280A1 (en) * 2001-05-01 2002-12-19 Angiotech Pharmaceuticals, Inc. Compositions and methods for treating inflammatory conditions utilizing protein or polysaccharide containing anti-microtubule agents
AU2002357012A1 (en) * 2001-11-27 2003-06-10 Transform Pharmaceuticals, Inc. Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof
EP1498120A1 (de) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Halbfeste Formulierung für die orale Verabreichung des Taxols

Also Published As

Publication number Publication date
MXPA06000633A (es) 2006-04-19
BRPI0412740A (pt) 2006-09-26
DE602004015994D1 (de) 2008-10-02
AR045911A1 (es) 2005-11-16
CN100566758C (zh) 2009-12-09
KR20060052834A (ko) 2006-05-19
MY139106A (en) 2009-08-28
WO2005014048A1 (en) 2005-02-17
EP1498143A1 (de) 2005-01-19
HK1089951A1 (en) 2006-12-15
EP1648517A1 (de) 2006-04-26
JP2009513557A (ja) 2009-04-02
CN1822859A (zh) 2006-08-23
US20090069411A1 (en) 2009-03-12
AU2004262495A1 (en) 2005-02-17
TW200518772A (en) 2005-06-16
CA2532566A1 (en) 2005-02-17
AU2004262495B2 (en) 2011-02-03
US20050025792A1 (en) 2005-02-03
TWI337870B (en) 2011-03-01
EP1648517B1 (de) 2008-08-20
IL173112A0 (en) 2006-06-11

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