AR045911A1 - Formulaciones auto-emulsionables y formulaciones auto-microemulsionables para la administracion oral de taxoides - Google Patents

Formulaciones auto-emulsionables y formulaciones auto-microemulsionables para la administracion oral de taxoides

Info

Publication number
AR045911A1
AR045911A1 ARP040102492A ARP040102492A AR045911A1 AR 045911 A1 AR045911 A1 AR 045911A1 AR P040102492 A ARP040102492 A AR P040102492A AR P040102492 A ARP040102492 A AR P040102492A AR 045911 A1 AR045911 A1 AR 045911A1
Authority
AR
Argentina
Prior art keywords
self
formulations
oral administration
taxoids
microemulsionable
Prior art date
Application number
ARP040102492A
Other languages
English (en)
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of AR045911A1 publication Critical patent/AR045911A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Formulaciones auto-emulsionables y formulaciones auto-microemulsionables para la administración oral de taxoides. Nuevas formulaciones de taxoides para administración oral. Reivindicación 1: Una formulación auto-microemulsionable para la administración oral de taxoides, que comprende al menos un taxoide, al menos un co-tensioactivo, al menos un aceite y un tensioactivo (Cremophor EL®). Reivindicación 11: Una formulación auto-microemulsionable según las reivindicaciones 1 a 10, donde la formulación comprende 60 % de Crempohor EL, 20 % de Imwitor 888 y 20 % de Miglycol 812N (porcentaje en peso).
ARP040102492A 2003-07-18 2004-07-15 Formulaciones auto-emulsionables y formulaciones auto-microemulsionables para la administracion oral de taxoides AR045911A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03291798A EP1498143A1 (en) 2003-07-18 2003-07-18 Self-emulsifying and self-microemulsifying formulations for the oral administration of taxoids

Publications (1)

Publication Number Publication Date
AR045911A1 true AR045911A1 (es) 2005-11-16

Family

ID=33462261

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040102492A AR045911A1 (es) 2003-07-18 2004-07-15 Formulaciones auto-emulsionables y formulaciones auto-microemulsionables para la administracion oral de taxoides

Country Status (17)

Country Link
US (2) US20050025792A1 (es)
EP (2) EP1498143A1 (es)
JP (1) JP2009513557A (es)
KR (1) KR20060052834A (es)
CN (1) CN100566758C (es)
AR (1) AR045911A1 (es)
AT (1) ATE405293T1 (es)
AU (1) AU2004262495B2 (es)
BR (1) BRPI0412740A (es)
CA (1) CA2532566A1 (es)
DE (1) DE602004015994D1 (es)
HK (1) HK1089951A1 (es)
IL (1) IL173112A0 (es)
MX (1) MXPA06000633A (es)
MY (1) MY139106A (es)
TW (1) TWI337870B (es)
WO (1) WO2005014048A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5250258B2 (ja) * 2005-04-20 2013-07-31 中外製薬株式会社 自己乳化型製剤処方の設計方法
DK1767545T3 (da) 2005-09-22 2010-03-15 Biocompatibles Uk Ltd GLP-1 (Glucagon-lignende peptid-1)-fusionspolypeptider med forøget peptidaseresistens
FR2922107B1 (fr) * 2007-10-10 2010-02-26 Aventis Pharma Sa Nouvelles compositions a base de taxoides
EP2217063B1 (en) * 2007-11-08 2014-12-17 Virginia Tech Intellectual Properties, Inc. Thiolated paclitaxels for reaction with gold nanoparticles as drug delivery agents
CN102228431A (zh) * 2010-03-16 2011-11-02 王国强 紫杉烷类化合物的自乳化药物组合物
CN101829052B (zh) * 2010-03-16 2011-12-14 王国强 紫杉烷类化合物的自乳化制剂及其制备方法
MY167224A (en) 2010-05-03 2018-08-14 Teikoku Pharma Usa Inc Non-Aqueous Taxane Pro-Emulsion Formulations and Methods of Making and Using the Same
JP2013209294A (ja) * 2010-07-30 2013-10-10 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 液状医薬組成物
GB2488788B (en) * 2011-03-07 2013-07-10 Natco Pharma Ltd Oral formulation of phenylaminopyrymidine compound with enhanced bioavailability and pharmacological response
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
KR101542364B1 (ko) * 2014-10-31 2015-08-07 대화제약 주식회사 탁산을 포함하는 경구 투여용 약학 조성물
TWI715636B (zh) * 2015-09-30 2021-01-11 香港商慧源香港創新有限公司 口服紫杉烷組合物及方法
CN109589305B (zh) * 2018-12-03 2021-03-19 昆明积大制药股份有限公司 多西他赛-环孢素a共包载自乳化制剂及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698582A (en) * 1991-07-08 1997-12-16 Rhone-Poulenc Rorer S.A. Compositions containing taxane derivatives
AU679013B2 (en) * 1992-10-16 1997-06-19 Ibah, Inc. Convertible microemulsion formulations
EP0684834A4 (en) * 1993-02-17 1996-09-25 Smithkline Beecham Corp MICROEMULSIONS CONTAINING THERAPEUTIC PEPTIDES.
US6964946B1 (en) * 1995-10-26 2005-11-15 Baker Norton Pharmaceuticals, Inc. Oral pharmaceutical compositions containing taxanes and methods of treatment employing the same
BE1011216A3 (fr) * 1997-06-13 1999-06-01 Thissen En Abrege L T B Lab Forme pharmaceutique pour l'administration de paclitaxel, procede de preparation d'une composition de paclitaxel prete a l'emploi et utilisation de cette composition.
AU756752B2 (en) * 1998-04-01 2003-01-23 Skyepharma Canada Inc. Anticancer compositions
AU4989299A (en) * 1998-07-14 2000-02-07 Em Industries, Inc. Microdisperse drug delivery systems
KR100602725B1 (ko) * 1998-12-11 2006-07-20 파마솔루션스, 인코포레이티드 물에서 불충분하게 용해되는 약제를 위한 자가-유화용조성물
US6267985B1 (en) * 1999-06-30 2001-07-31 Lipocine Inc. Clear oil-containing pharmaceutical compositions
DE19925211B4 (de) * 1999-06-01 2006-01-12 PBS Pharmaceutical Bulk Substances SA Kit zur Herstellung einer Formulierung von Paclitaxel
WO2001028519A1 (de) * 1999-10-20 2001-04-26 Vesifact Ag Mikroemulsion-prekonzentrate und mikroemulsionen
CA2434641A1 (en) * 2001-01-18 2002-08-22 Pharmacia And Upjohn Company Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
WO2002087563A2 (en) * 2001-05-01 2002-11-07 Angiotech Pharmaceuticals Inc. Compositions comprising an anti-microtubule agent and a polypeptide or a polysaccharide and the use thereof for the preparation of a medicament for the treatment of inflammatory conditions
AU2002357012A1 (en) * 2001-11-27 2003-06-10 Transform Pharmaceuticals, Inc. Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof
EP1498120A1 (en) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Semi-solid formulations for the oral administration of taxoids

Also Published As

Publication number Publication date
AU2004262495B2 (en) 2011-02-03
BRPI0412740A (pt) 2006-09-26
KR20060052834A (ko) 2006-05-19
CN100566758C (zh) 2009-12-09
US20090069411A1 (en) 2009-03-12
CN1822859A (zh) 2006-08-23
MY139106A (en) 2009-08-28
JP2009513557A (ja) 2009-04-02
MXPA06000633A (es) 2006-04-19
TWI337870B (en) 2011-03-01
TW200518772A (en) 2005-06-16
EP1648517B1 (en) 2008-08-20
ATE405293T1 (de) 2008-09-15
US20050025792A1 (en) 2005-02-03
HK1089951A1 (en) 2006-12-15
WO2005014048A1 (en) 2005-02-17
AU2004262495A1 (en) 2005-02-17
CA2532566A1 (en) 2005-02-17
EP1498143A1 (en) 2005-01-19
EP1648517A1 (en) 2006-04-26
IL173112A0 (en) 2006-06-11
DE602004015994D1 (de) 2008-10-02

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